iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oan-073057

Ensembl Protein ID

ENSOANP00000024620.3

UniProt Accession

F7G4F4; F7G4F4_ORNAN

Protein Name

Uncharacterized protein

Gene Name

ARHGEF7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000015625.3	ENSOANT00000024624.2	ENSOANP00000024620.3
ENSOANG00000015625.3	ENSOANT00000024623.2	ENSOANP00000024619.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	6.70e-15	55.0	10	64

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++ ++++ +n+deL++ kGd+++v     +++gW++g  + +gk G fP+n+v++++
   Q: 10   VVRAKFNFQQTNEDELSFAKGDIIHVT--RVEEGGWWEG--THNGKTGWFPSNYVREIK 64
           68999*********************7..999*******..8**************997 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MTDNSNHQLV VRAKFNFQQT NEDELSFAKG DIIHVTRVEE GGWWEGTHNG KTGWFPSNYV 60
REIKSNEKPV SPKSGSLKSP PKGFDTSAIN KSYYNVVLQN ILETENEYAK ELQTILSTYL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAGACATCG GCCTGGGAAG CGACTCCGTA TGTACTCGGC CCTCGTCTCA TCGAATCAAG 60
TCCTTTGACT CCCTTGGATC CCAGTCTTTG CTCAGTCGGA GTTCAAAATT GTTCCAGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-1185--Reference proteome

Interpro

IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR032409--GEF_CC
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF16523--betaPIX_CC
PF00169--PH
PF00621--RhoGEF
PF07653--SH3_2

PRINTS

PR00452--SH3DOMAIN

SMART

SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0043005--C:neuron projection
GO:0043025--C:neuronal cell body
GO:0005886--C:plasma membrane
GO:0043234--C:protein complex
GO:0000322--C:storage vacuole
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0048041--P:focal adhesion assembly
GO:0007030--P:Golgi organization
GO:0002244--P:hematopoietic progenitor cell differentiation
GO:0035556--P:intracellular signal transduction
GO:0030032--P:lamellipodium assembly
GO:0043065--P:positive regulation of apoptotic process
GO:0010763--P:positive regulation of fibroblast migration
GO:0060124--P:positive regulation of growth hormone secretion
GO:2000394--P:positive regulation of lamellipodium morphogenesis
GO:0032092--P:positive regulation of protein binding
GO:1900026--P:positive regulation of substrate adhesion-dependent cell spreading
GO:1904424--P:regulation of GTP binding
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001259	Ailuropoda melanoleuca	92.67	0.00e+00	1023.00
IUUC-Aca-004591	Anolis carolinensis	93.48	0.00e+00	1129.00
IUUC-Ame-010759	Astyanax mexicanus	76.55	0.00e+00	1056.00
IUUC-Bta-013328	Bos taurus	92.48	0.00e+00	1214.00
IUUC-Bci-013864	Botrytis cinerea	41.54	3.00e-11	63.90
IUUC-Cja-018742	Callithrix jacchus	92.35	0.00e+00	1024.00
IUUC-Cfa-020756	Canis familiaris	92.25	0.00e+00	982.00
IUUC-Cpo-021284	Cavia porcellus	92.06	0.00e+00	1148.00
IUUC-Csa-023162	Chlorocebus sabaeus	93.33	0.00e+00	1204.00
IUUC-Cho-024736	Choloepus hoffmanni	69.57	7.00e-132	463.00
IUUC-Cin-025535	Ciona intestinalis	41.47	1.00e-95	343.00
IUUC-Cgl-026676	Colletotrichum gloeosporioides	42.86	1.00e-11	65.50
IUUC-Cne-026866	Cryptococcus neoformans	49.21	1.00e-12	68.60
IUUC-Dre-028646	Danio rerio	76.35	0.00e+00	1062.00
IUUC-Dno-029461	Dasypus novemcinctus	94.89	0.00e+00	1213.00
IUUC-Dor-030623	Dipodomys ordii	80.62	0.00e+00	845.00
IUUC-Dme-032219	Drosophila melanogaster	45.74	5.00e-102	365.00
IUUC-Ete-032236	Echinops telfairi	77.03	0.00e+00	656.00
IUUC-Eca-034137	Equus caballus	94.33	0.00e+00	1202.00
IUUC-Fca-035742	Felis catus	92.07	0.00e+00	949.00
IUUC-Fal-037205	Ficedula albicollis	95.46	0.00e+00	1217.00
IUUC-Fox-037757	Fusarium oxysporum	38.89	3.00e-11	64.30
IUUC-Fso-038433	Fusarium solani	40.28	8.00e-12	65.90
IUUC-Gmo-039475	Gadus morhua	67.94	0.00e+00	870.00
IUUC-Gga-040539	Gallus gallus	79.29	0.00e+00	999.00
IUUC-Gac-042615	Gasterosteus aculeatus	63.74	0.00e+00	790.00
IUUC-Ggo-044470	Gorilla gorilla	87.57	0.00e+00	1121.00
IUUC-Hsa-046398	Homo sapiens	92.35	0.00e+00	1025.00
IUUC-Kpa-049278	Komagataella pastoris	28.03	4.00e-17	83.20
IUUC-Loc-052146	Lepisosteus oculatus	86.10	0.00e+00	1155.00
IUUC-Lma-053273	Leptosphaeria maculans	40.32	2.00e-10	61.60
IUUC-Laf-053891	Loxodonta africana	94.47	0.00e+00	1258.00
IUUC-Mcc-055483	Macaca mulatta	92.18	0.00e+00	1024.00
IUUC-Mla-059044	Melampsora laricipopulina	26.16	5.00e-19	89.70
IUUC-Mga-059410	Meleagris gallopavo	95.04	0.00e+00	1215.00
IUUC-Mmr-060758	Microcebus murinus	93.00	0.00e+00	981.00
IUUC-Mdo-061900	Monodelphis domestica	80.14	0.00e+00	1016.00
IUUC-Mmu-063849	Mus musculus	90.55	0.00e+00	972.00
IUUC-Mpu-065876	Mustela putorius furo	91.35	0.00e+00	971.00
IUUC-Mlu-067970	Myotis lucifugus	94.18	0.00e+00	1204.00
IUUC-Ncr-068791	Neurospora crassa	47.37	2.00e-11	64.70
IUUC-Nle-069685	Nomascus leucogenys	74.33	0.00e+00	1003.00
IUUC-Opr-071132	Ochotona princeps	63.36	0.00e+00	635.00
IUUC-Ont-071815	Oreochromis niloticus	75.92	0.00e+00	1051.00
IUUC-Ola-086663	Oryzias latipes	73.94	0.00e+00	971.00
IUUC-Oga-088103	Otolemur garnettii	92.77	0.00e+00	1148.00
IUUC-Ptr-091162	Pan troglodytes	92.18	0.00e+00	1022.00
IUUC-Pan-092093	Papio anubis	82.07	0.00e+00	1061.00
IUUC-Pma-094261	Petromyzon marinus	65.82	7.00e-124	436.00
IUUC-Pfo-096736	Poecilia formosa	66.52	0.00e+00	865.00
IUUC-Pab-097641	Pongo abelii	91.89	0.00e+00	971.00
IUUC-Pva-102819	Pteropus vampyrus	89.74	0.00e+00	962.00
IUUC-Pgr-103400	Puccinia graminis	27.00	1.00e-19	91.70
IUUC-Pte-104123	Pyrenophora teres	42.86	3.00e-10	60.50
IUUC-Pyt-104567	Pyrenophora triticirepentis	42.86	3.00e-10	60.50
IUUC-Rno-106099	Rattus norvegicus	91.77	0.00e+00	1145.00
IUUC-Sha-106845	Sarcophilus harrisii	80.28	0.00e+00	1019.00
IUUC-Sja-107728	Schizosaccharomyces japonicus	22.84	6.00e-10	58.90
IUUC-Ssc-116036	Sus scrofa	90.45	0.00e+00	944.00
IUUC-Tgu-117498	Taeniopygia guttata	95.46	0.00e+00	1218.00
IUUC-Tru-118278	Takifugu rubripes	73.83	0.00e+00	985.00
IUUC-Tsy-118990	Tarsius syrichta	89.47	0.00e+00	800.00
IUUC-Tni-120394	Tetraodon nigroviridis	64.30	0.00e+00	841.00
IUUC-Tre-121917	Trichoderma reesei	45.61	1.00e-11	65.10
IUUC-Tvi-122534	Trichoderma virens	45.61	1.00e-11	65.10
IUUC-Ttr-128922	Tursiops truncatus	87.62	0.00e+00	933.00
IUUC-Xtr-132012	Xenopus tropicalis	85.98	0.00e+00	1070.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence