iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aml-001898

Ensembl Protein ID

ENSAMEP00000004029.1

UniProt Accession

G1LAV6; G1LAV6_AILME

Genbank Protein ID

ENSAMEP00000004029

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01043318

Gene Name

DDX58

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000003766.1	ENSAMET00000004193.1	ENSAMEP00000004029.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	2.80e-44	149.6	101	172

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 3    eeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktL..vqkegWfrefl 73
           eeyrlll++lq++++++  ++d+l  ++s +l+ +e+e+i++ +++kg m++ae++ ++L  ++ke+W+++++
   Q: 101  EEYRLLLKRLQPEFKTTVNPKDILP-EISGCLISQECEEIIQVCSNKGLMAGAEKMAECLlrSDKENWPKTLK 172
           9************************.********************************************985 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MSAEDRQNLH AFRDYVVKTL DPTYILSYMA PWFKDDKVQH IQAEKNNKGT TEAASLFLKF 60
LLELQEEGWF RGFLDALGHA GYSGLYEAIE TWDFRKIESL EEYRLLLKRL QPEFKTTVNP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGGCTG AGGATCGGCA GAATCTGCAC GCCTTCCGGG ACTATGTCGT GAAGACTCTG 60
GACCCTACGT ACATCCTGAG CTACATGGCC CCCTGGTTTA AGGACGGTGA GTGGTCCCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR031964--CARD_dom
IPR011029--DEATH-like_dom
IPR006935--Helicase/UvrB_N
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00271--Helicase_C
PF04851--ResIII
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005923--C:bicellular tight junction
GO:0005829--C:cytosol
GO:0032587--C:ruffle membrane
GO:0005524--F:ATP binding
GO:0003690--F:double-stranded DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0009597--P:detection of virus
GO:0045087--P:innate immune response
GO:0002230--P:positive regulation of defense response to virus by host
GO:0032725--P:positive regulation of granulocyte macrophage colony-stimulating factor production
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0032755--P:positive regulation of interleukin-6 production
GO:0032757--P:positive regulation of interleukin-8 production
GO:0042993--P:positive regulation of transcription factor import into nucleus
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0030334--P:regulation of cell migration
GO:0043330--P:response to exogenous dsRNA
GO:0039529--P:RIG-I signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003966	Anas platyrhynchos	52.31	0.00e+00	889.00
IUUC-Aca-004499	Anolis carolinensis	46.64	0.00e+00	790.00
IUUC-Ame-011950	Astyanax mexicanus	42.71	0.00e+00	699.00
IUUC-Bta-012489	Bos taurus	81.16	0.00e+00	1500.00
IUUC-Cel-018230	Caenorhabditis elegans	30.30	1.00e-72	268.00
IUUC-Cja-018716	Callithrix jacchus	78.52	0.00e+00	1478.00
IUUC-Cfa-020269	Canis familiaris	88.70	0.00e+00	1680.00
IUUC-Cpo-022507	Cavia porcellus	73.53	0.00e+00	1368.00
IUUC-Csa-024209	Chlorocebus sabaeus	78.95	0.00e+00	1487.00
IUUC-Cho-025104	Choloepus hoffmanni	72.59	0.00e+00	1166.00
IUUC-Cin-025792	Ciona intestinalis	32.55	2.00e-81	296.00
IUUC-Cgl-026385	Colletotrichum gloeosporioides	24.72	2.00e-19	92.00
IUUC-Dno-028954	Dasypus novemcinctus	76.93	0.00e+00	1392.00
IUUC-Eca-034039	Equus caballus	83.12	0.00e+00	1543.00
IUUC-Eeu-035009	Erinaceus europaeus	70.09	0.00e+00	920.00
IUUC-Fca-036169	Felis catus	87.65	0.00e+00	1648.00
IUUC-Fal-037579	Ficedula albicollis	52.90	0.00e+00	905.00
IUUC-Fso-038398	Fusarium solani	25.84	9.00e-20	93.20
IUUC-Ggo-045318	Gorilla gorilla	77.70	0.00e+00	1355.00
IUUC-Hsa-046671	Homo sapiens	79.70	0.00e+00	1470.00
IUUC-Itr-047996	Ictidomys tridecemlineatus	74.68	0.00e+00	1377.00
IUUC-Lch-050461	Latimeria chalumnae	50.22	0.00e+00	860.00
IUUC-Loc-052582	Lepisosteus oculatus	46.48	0.00e+00	822.00
IUUC-Laf-054324	Loxodonta africana	78.37	0.00e+00	1438.00
IUUC-Mcc-055390	Macaca mulatta	78.09	0.00e+00	1465.00
IUUC-Meu-056365	Macropus eugenii	61.85	6.00e-126	444.00
IUUC-Mpo-057328	Magnaporthe poae	25.35	3.10e-01	31.20
IUUC-Mmr-061407	Microcebus murinus	79.59	0.00e+00	1526.00
IUUC-Mmu-063939	Mus musculus	73.44	0.00e+00	1367.00
IUUC-Mpu-066226	Mustela putorius furo	89.29	0.00e+00	1566.00
IUUC-Mlu-068092	Myotis lucifugus	82.30	0.00e+00	1492.00
IUUC-Nfi-068405	Neosartorya fischeri	24.26	1.00e-20	95.90
IUUC-Opr-070246	Ochotona princeps	64.89	0.00e+00	654.00
IUUC-Oan-072742	Ornithorhynchus anatinus	59.26	0.00e+00	952.00
IUUC-Ocu-073959	Oryctolagus cuniculus	72.72	0.00e+00	1373.00
IUUC-Oga-089173	Otolemur garnettii	78.41	0.00e+00	1457.00
IUUC-Oar-089369	Ovis aries	80.65	0.00e+00	1463.00
IUUC-Ptr-091032	Pan troglodytes	79.70	0.00e+00	1470.00
IUUC-Pan-092383	Papio anubis	78.84	0.00e+00	1482.00
IUUC-Psi-093432	Pelodiscus sinensis	54.98	0.00e+00	1034.00
IUUC-Pma-094367	Petromyzon marinus	41.34	4.00e-114	405.00
IUUC-Pab-098416	Pongo abelii	80.11	0.00e+00	1380.00
IUUC-Pca-101006	Procavia capensis	80.00	0.00e+00	671.00
IUUC-Pva-102966	Pteropus vampyrus	82.58	0.00e+00	1540.00
IUUC-Pgr-103529	Puccinia graminis	26.02	9.00e-28	119.00
IUUC-Rno-105059	Rattus norvegicus	73.53	0.00e+00	890.00
IUUC-Ssl-108450	Sclerotinia sclerotiorum	27.78	6.00e-04	41.20
IUUC-Sar-113202	Sorex araneus	67.32	0.00e+00	1034.00
IUUC-Ssc-116120	Sus scrofa	80.32	0.00e+00	1467.00
IUUC-Tgu-117314	Taeniopygia guttata	52.33	0.00e+00	930.00
IUUC-Tsy-119453	Tarsius syrichta	78.14	0.00e+00	837.00
IUUC-Tre-122194	Trichoderma reesei	25.19	3.00e-16	81.60
IUUC-Ttr-128421	Tursiops truncatus	77.95	0.00e+00	1216.00
IUUC-Vpa-130602	Vicugna pacos	79.33	0.00e+00	1398.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence