iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-117074

UUCD1 version

UUC-TaG-00898

Ensembl Protein ID

ENSTGUP00000001738.1

UniProt Accession

B5FYL2; B5FYL2_TAEGU

Genbank Protein ID

ACH44123.1; ACH44124.1; ACH44125.1

Protein Name

Putative ubiquitin conjugating enzyme E2 variant 1; Putative ubiquitin conjugating enzyme E2 variant 2

Genbank Nucleotide ID

ABQF01020570; DQ214035; DQ214036

Gene Name

UBE2R2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000001683.1	ENSTGUT00000001754.1	ENSTGUP00000001738.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.10e-49	166.7	13	153

Active Site

Position(s)	Description	Evidence
93	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 2    lkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk... 87
           l+ elk+l+++p+eg+++++vdesdl++wev+i+Gp++t Yegg+Fk++i+fp dYP++PP+++fltk++hPn+yenG+vC+sil+   
   Q: 13   LMLELKSLQEEPVEGFRITLVDESDLYNWEVAIFGPPNTLYEGGYFKAHIKFPIDYPYSPPTFRFLTKMWHPNIYENGDVCISILHppv 101
           678**********************************************************************************9999 PP
   S: 88   ........eeekWspalsvesvllsiqsllaepnpesplneeaaellkknre 131
                   ++e+W+p+++v+++lls++sll+epn+ sp+n++a+ +++k+r 
   Q: 102  ddpqsgelPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMFRKWRD 153
           99999*9*************************************99998875 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

MAQQQMSSSQ KALMLELKSL QEEPVEGFRI TLVDESDLYN WEVAIFGPPN TLYEGGYFKA 60
HIKFPIDYPY SPPTFRFLTK MWHPNIYENG DVCISILHPP VDDPQSGELP SERWNPTQNV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGGTCAGCG CGAGCGGCGC CGTCACAAAA GGAAGTAGCG GCTGCGGGGC CGTCAGCGCG 60
AGGAGGGGCG GGGGCGGCAC CGGCACCGGT ACCGGCGCCA CCGGCAGCGG GAGCACCGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0070936--P:protein K48-linked ubiquitination
GO:0006513--P:protein monoubiquitination

KEGG

tgu:100049550

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003563	Anas platyrhynchos	98.64	3.00e-85	306.00
IUUC-Aca-004589	Anolis carolinensis	98.03	2.00e-118	417.00
IUUC-Ate-010563	Aspergillus terreus	45.16	4.00e-37	147.00
IUUC-Ame-011300	Astyanax mexicanus	95.48	3.00e-114	404.00
IUUC-Bta-012968	Bos taurus	99.47	7.00e-112	395.00
IUUC-Cel-018460	Caenorhabditis elegans	65.97	1.00e-74	271.00
IUUC-Cja-018764	Callithrix jacchus	99.01	2.00e-119	421.00
IUUC-Cfa-020955	Canis familiaris	99.01	2.00e-119	421.00
IUUC-Cpo-021451	Cavia porcellus	99.01	2.00e-119	421.00
IUUC-Csa-024239	Chlorocebus sabaeus	99.01	2.00e-119	421.00
IUUC-Cho-024999	Choloepus hoffmanni	81.67	3.00e-26	111.00
IUUC-Cin-025257	Ciona intestinalis	70.05	1.00e-85	308.00
IUUC-Csv-025954	Ciona savignyi	71.57	1.00e-87	315.00
IUUC-Dre-028153	Danio rerio	94.09	1.00e-114	404.00
IUUC-Dno-029368	Dasypus novemcinctus	99.47	7.00e-112	395.00
IUUC-Dor-030686	Dipodomys ordii	99.01	2.00e-119	421.00
IUUC-Dme-032106	Drosophila melanogaster	74.61	4.00e-89	320.00
IUUC-Ete-033001	Echinops telfairi	99.13	4.00e-64	236.00
IUUC-Eca-034221	Equus caballus	98.63	3.00e-84	303.00
IUUC-Fca-036381	Felis catus	97.97	7.00e-85	305.00
IUUC-Fal-037135	Ficedula albicollis	100.00	4.00e-115	406.00
IUUC-Gmo-039565	Gadus morhua	93.43	1.00e-111	394.00
IUUC-Gga-040477	Gallus gallus	100.00	3.00e-115	407.00
IUUC-Gac-041909	Gasterosteus aculeatus	92.42	5.00e-111	392.00
IUUC-Ggo-045150	Gorilla gorilla	98.52	1.00e-118	417.00
IUUC-Hsa-046611	Homo sapiens	99.01	2.00e-119	421.00
IUUC-Itr-047984	Ictidomys tridecemlineatus	91.63	9.00e-106	375.00
IUUC-Lch-050173	Latimeria chalumnae	99.01	1.00e-119	421.00
IUUC-Loc-051916	Lepisosteus oculatus	97.01	2.00e-114	404.00
IUUC-Laf-053860	Loxodonta africana	99.01	2.00e-119	421.00
IUUC-Mcc-054820	Macaca mulatta	99.01	2.00e-119	421.00
IUUC-Meu-056681	Macropus eugenii	94.09	5.00e-113	399.00
IUUC-Mmr-060666	Microcebus murinus	99.01	2.00e-119	421.00
IUUC-Mdo-062804	Monodelphis domestica	99.51	3.00e-120	423.00
IUUC-Mmu-063472	Mus musculus	99.01	2.00e-119	421.00
IUUC-Mlu-067397	Myotis lucifugus	94.42	1.00e-109	388.00
IUUC-Nle-070152	Nomascus leucogenys	99.08	3.00e-63	232.00
IUUC-Ont-071627	Oreochromis niloticus	92.50	3.00e-112	397.00
IUUC-Ocu-074229	Oryctolagus cuniculus	99.48	2.00e-112	397.00
IUUC-Ola-086587	Oryzias latipes	91.92	4.00e-111	393.00
IUUC-Oga-089161	Otolemur garnettii	99.47	7.00e-112	395.00
IUUC-Oar-089383	Ovis aries	99.01	2.00e-119	421.00
IUUC-Ptr-091096	Pan troglodytes	99.01	2.00e-119	421.00
IUUC-Pan-092560	Papio anubis	99.47	7.00e-112	395.00
IUUC-Psi-093263	Pelodiscus sinensis	99.32	6.00e-85	305.00
IUUC-Pma-094368	Petromyzon marinus	87.50	2.00e-75	273.00
IUUC-Pfo-096974	Poecilia formosa	92.93	1.00e-111	395.00
IUUC-Pab-098344	Pongo abelii	99.01	2.00e-119	421.00
IUUC-Rno-105821	Rattus norvegicus	99.01	2.00e-119	421.00
IUUC-Sha-107364	Sarcophilus harrisii	99.51	3.00e-120	423.00
IUUC-Sar-112992	Sorex araneus	95.02	5.00e-109	386.00
IUUC-Tru-118641	Takifugu rubripes	91.88	5.00e-110	389.00
IUUC-Tsy-118797	Tarsius syrichta	96.38	4.00e-77	279.00
IUUC-Tni-119817	Tetraodon nigroviridis	91.92	1.00e-110	392.00
IUUC-Tbe-128014	Tupaia belangeri	99.01	2.00e-119	421.00
IUUC-Ttr-129037	Tursiops truncatus	98.92	6.00e-107	379.00
IUUC-Vpa-130680	Vicugna pacos	99.31	2.00e-83	300.00
IUUC-Xtr-131819	Xenopus tropicalis	99.46	9.00e-109	385.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence