iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000002154.3	ENSXETT00000064138.1	ENSXETP00000060592.1
ENSXETG00000002154.3	ENSXETT00000004592.2	ENSXETP00000004592.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.20e-49	166.9	2	142

Active Site

Position(s)	Description	Evidence
93	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 2    lkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk... 87
           l+ elk+l+++p+eg+++++vdesdl++wev+i+Gp++t Yegg+Fk++i+fp dYP++PP+++fltk++hPn+yenG+vC+sil+   
   Q: 2    LMLELKSLQEEPVEGFRITLVDESDLYNWEVAIFGPPNTLYEGGYFKAHIKFPIDYPYSPPTFRFLTKMWHPNIYENGDVCISILHppv 90
           688**********************************************************************************9999 PP
   S: 88   ........eeekWspalsvesvllsiqsllaepnpesplneeaaellkknre 131
                   ++e+W+p+++v+++lls++sll+epn+ sp+n++a+ +++k+r 
   Q: 91   ddpqsgelPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMFRKWRD 142
           99999*9*************************************99998875 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

XLMLELKSLQ EEPVEGFRIT LVDESDLYNW EVAIFGPPNT LYEGGYFKAH IKFPIDYPYS 60
PPTFRFLTKM WHPNIYENGD VCISILHPPV DDPQSGELPS ERWNPTQNVR TILLSVISLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTGCCCCCC CCCCATACCC TGCTGGGAGA AGCACCCNNN NNNNNNNNNN NNNNNNNNNN 60
NNNNNNNNNN NNNNNNNNNN NNNNNNNCCT GATGTTGGAG CTGAAGTCCC TGCAGGAAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003563	Anas platyrhynchos	97.28	2.00e-83	300.00
IUUC-Aca-004589	Anolis carolinensis	97.91	2.00e-111	394.00
IUUC-Ate-010563	Aspergillus terreus	46.15	1.00e-36	145.00
IUUC-Ame-011300	Astyanax mexicanus	96.24	5.00e-107	380.00
IUUC-Bta-012968	Bos taurus	99.47	3.00e-111	393.00
IUUC-Cel-018460	Caenorhabditis elegans	67.96	2.00e-73	268.00
IUUC-Cja-018764	Callithrix jacchus	99.48	2.00e-112	398.00
IUUC-Cfa-020955	Canis familiaris	99.48	2.00e-112	398.00
IUUC-Cpo-021451	Cavia porcellus	99.48	2.00e-112	398.00
IUUC-Csa-024239	Chlorocebus sabaeus	99.48	2.00e-112	398.00
IUUC-Cho-024999	Choloepus hoffmanni	81.67	6.00e-26	110.00
IUUC-Cin-025257	Ciona intestinalis	70.68	5.00e-84	303.00
IUUC-Csv-025954	Ciona savignyi	72.25	2.00e-85	308.00
IUUC-Dre-028153	Danio rerio	94.76	8.00e-108	382.00
IUUC-Dno-029368	Dasypus novemcinctus	99.47	3.00e-111	393.00
IUUC-Dor-030686	Dipodomys ordii	99.48	2.00e-112	398.00
IUUC-Dme-032106	Drosophila melanogaster	74.35	3.00e-87	315.00
IUUC-Ete-033001	Echinops telfairi	99.13	1.00e-63	234.00
IUUC-Eca-034221	Equus caballus	98.63	9.00e-84	301.00
IUUC-Fca-036381	Felis catus	97.97	3.00e-84	303.00
IUUC-Fal-037135	Ficedula albicollis	98.95	4.00e-111	393.00
IUUC-Gmo-039565	Gadus morhua	94.62	4.00e-106	376.00
IUUC-Gga-040477	Gallus gallus	98.95	2.00e-111	394.00
IUUC-Gac-041909	Gasterosteus aculeatus	94.09	5.00e-106	376.00
IUUC-Ggo-045150	Gorilla gorilla	98.95	1.00e-111	395.00
IUUC-Hsa-046611	Homo sapiens	99.48	2.00e-112	398.00
IUUC-Itr-047984	Ictidomys tridecemlineatus	91.62	8.00e-99	352.00
IUUC-Lch-050173	Latimeria chalumnae	98.43	3.00e-111	394.00
IUUC-Loc-051916	Lepisosteus oculatus	97.34	1.00e-106	378.00
IUUC-Laf-053860	Loxodonta africana	99.48	2.00e-112	398.00
IUUC-Mcc-054820	Macaca mulatta	99.48	2.00e-112	398.00
IUUC-Meu-056681	Macropus eugenii	93.19	2.00e-104	371.00
IUUC-Mmr-060666	Microcebus murinus	99.48	2.00e-112	398.00
IUUC-Mdo-062804	Monodelphis domestica	98.95	9.00e-112	395.00
IUUC-Mmu-063472	Mus musculus	99.48	2.00e-112	398.00
IUUC-Mlu-067397	Myotis lucifugus	96.22	2.00e-104	371.00
IUUC-Nle-070152	Nomascus leucogenys	99.08	9.00e-63	231.00
IUUC-Ont-071627	Oreochromis niloticus	94.15	6.00e-107	379.00
IUUC-Ocu-074229	Oryctolagus cuniculus	99.48	1.00e-111	395.00
IUUC-Ola-086587	Oryzias latipes	93.55	7.00e-106	376.00
IUUC-Oga-089161	Otolemur garnettii	99.47	2.00e-111	394.00
IUUC-Oar-089383	Ovis aries	99.48	2.00e-112	398.00
IUUC-Ptr-091096	Pan troglodytes	99.48	2.00e-112	398.00
IUUC-Pan-092560	Papio anubis	99.47	3.00e-111	393.00
IUUC-Psi-093263	Pelodiscus sinensis	97.95	5.00e-83	299.00
IUUC-Pfo-096974	Poecilia formosa	94.09	3.00e-106	377.00
IUUC-Pab-098344	Pongo abelii	99.48	2.00e-112	398.00
IUUC-Rno-105821	Rattus norvegicus	99.48	2.00e-112	398.00
IUUC-Sha-107364	Sarcophilus harrisii	98.95	9.00e-112	395.00
IUUC-Sar-112992	Sorex araneus	95.83	2.00e-104	371.00
IUUC-Tgu-117074	Taeniopygia guttata	98.95	4.00e-111	393.00
IUUC-Tru-118641	Takifugu rubripes	92.97	1.00e-104	372.00
IUUC-Tsy-118797	Tarsius syrichta	97.10	3.00e-77	280.00
IUUC-Tbe-128014	Tupaia belangeri	99.48	2.00e-112	398.00
IUUC-Ttr-129037	Tursiops truncatus	98.92	3.00e-106	377.00
IUUC-Vpa-130680	Vicugna pacos	99.31	8.00e-83	298.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence