iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-007162

UUCD1 version

UUC-ArT-01600

Ensembl Protein ID

AT5G05080.2

UniProt Accession

Q9FF66; UBC22_ARATH

Genbank Protein ID

AAY44862.1; BAB11530.1; AED90825.1; AED90826.1; ANM71122.1; ANM71123.1; AAM51582.1; AAL16250.1; AAM65652.1

Protein Name

Ubiquitin-conjugating enzyme E2 22; E2 ubiquitin-conjugating enzyme 22; Ubiquitin carrier protein 22

Genbank Nucleotide ID

DQ027036; AB005245; CP002688; CP002688; CP002688; CP002688; AY116948; AF428320; AY088106

Gene Name

UBC22; At5g05080; MUG13.6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT5G05080	AT5G05080.2	AT5G05080.2

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E2/UBC	E2_UBC	19348673; 16339806

Classification

Family	E-value	Score	Start	End
E2/UBC	4.30e-37	127.8	15	148

Active Site

Position(s)	Description	Evidence
94	Glycyl thioester intermediate	{ECO:0000255\|PROSITE-ProRule:PRU00388, ECO:0000255\|PROSITE-ProRule:PRU10133}

Domain Profile

E2/UBC

   S: 2    lkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWspalsve 99
           l+kelk+l+++pp+gi++ ++de d+ ++ + i+Gp +tpYe+g+F++++ +++d+P +PPk  f+tkifhPnv +nG++C++ lk  ++W+p l ++
   Q: 15   LAKELKSLDESPPDGIKVVVNDE-DFSQICADIEGPVGTPYENGLFRMKLALSHDFPHSPPKGYFMTKIFHPNVASNGEICVNTLK--KDWNPSLGLR 109
           78********************9.9************************************************************9..********** PP
   S: 100  svllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           +vl  +  ll ep pes+lne+a ++l +n  ey +++r
   Q: 110  HVLSVVRCLLIEPFPESALNEQAGKMLLENYDEYARHAR 148
           **********************************99876 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.

Protein Sequence
(Fasta)

MASNENLPPN VIKQLAKELK SLDESPPDGI KVVVNDEDFS QICADIEGPV GTPYENGLFR 60
MKLALSHDFP HSPPKGYFMT KIFHPNVASN GEICVNTLKK DWNPSLGLRH VLSVVRCLLI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATAAAAATTC AATAATTGAA CCTCCTCTCT CTCTCTCTCT TCTCTCCCTT CTTCTTCTCC 60
GATTTCGACT TTGAATCATT TCTTCGAGAG AGGTAGCGAG AAAGGGATCG CCTTTTCTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0832--Ubl conjugation
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0000209--P:protein polyubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ath:AT5G05080

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000904	Aegilops tauschii	70.04	6.00e-88	316.00
IUUC-Aml-001979	Ailuropoda melanoleuca	65.33	2.00e-58	217.00
IUUC-Atr-002706	Amborella trichopoda	68.68	2.00e-85	308.00
IUUC-Aca-004432	Anolis carolinensis	64.02	1.00e-60	225.00
IUUC-Aly-005779	Arabidopsis lyrata	94.85	9.00e-124	435.00
IUUC-Acl-008107	Aspergillus clavatus	42.44	1.00e-34	140.00
IUUC-Afl-008578	Aspergillus flavus	48.48	1.00e-33	136.00
IUUC-Afu-009034	Aspergillus fumigatus	44.81	8.00e-35	140.00
IUUC-Ani-009151	Aspergillus nidulans	53.33	5.00e-35	141.00
IUUC-Ang-009649	Aspergillus niger	50.74	1.00e-36	147.00
IUUC-Ate-010468	Aspergillus terreus	54.35	1.00e-26	113.00
IUUC-Ame-010836	Astyanax mexicanus	59.62	5.00e-54	203.00
IUUC-Bta-012740	Bos taurus	65.16	3.00e-58	217.00
IUUC-Bdi-014057	Brachypodium distachyon	68.65	3.00e-85	307.00
IUUC-Bol-015087	Brassica oleracea	90.23	5.00e-118	416.00
IUUC-Bra-016867	Brassica rapa	90.61	3.00e-122	430.00
IUUC-Cja-019763	Callithrix jacchus	59.66	1.00e-58	218.00
IUUC-Cfa-020216	Canis familiaris	65.16	1.00e-58	218.00
IUUC-Cpo-021720	Cavia porcellus	60.12	1.00e-58	218.00
IUUC-Cre-022676	Chlamydomonas reinhardtii	58.28	3.00e-54	203.00
IUUC-Csa-023751	Chlorocebus sabaeus	60.23	4.00e-59	219.00
IUUC-Cho-024620	Choloepus hoffmanni	63.89	1.00e-40	157.00
IUUC-Cin-025632	Ciona intestinalis	58.33	2.00e-55	207.00
IUUC-Csv-025984	Ciona savignyi	57.69	2.00e-54	204.00
IUUC-Cne-026844	Cryptococcus neoformans	46.29	4.00e-48	183.00
IUUC-Cme-027294	Cyanidioschyzon merolae	54.66	2.00e-51	194.00
IUUC-Dre-027674	Danio rerio	60.26	1.00e-54	204.00
IUUC-Dno-029886	Dasypus novemcinctus	65.16	2.00e-58	217.00
IUUC-Dor-030440	Dipodomys ordii	64.74	1.00e-58	218.00
IUUC-Dse-031211	Dothistroma septosporum	42.02	2.00e-27	113.00
IUUC-Dme-031888	Drosophila melanogaster	62.09	2.00e-59	221.00
IUUC-Ete-032365	Echinops telfairi	71.43	1.00e-44	171.00
IUUC-Eca-033733	Equus caballus	64.90	5.00e-58	216.00
IUUC-Eeu-035342	Erinaceus europaeus	66.00	8.00e-58	215.00
IUUC-Fca-035964	Felis catus	64.15	2.00e-39	154.00
IUUC-Gmo-039357	Gadus morhua	60.93	3.00e-54	204.00
IUUC-Gga-040261	Gallus gallus	60.71	8.00e-38	149.00
IUUC-Gac-042593	Gasterosteus aculeatus	60.26	3.00e-54	203.00
IUUC-Gma-042876	Glycine max	90.50	4.00e-98	350.00
IUUC-Ggo-044626	Gorilla gorilla	63.78	3.00e-45	173.00
IUUC-Hsa-046058	Homo sapiens	64.74	5.00e-59	219.00
IUUC-Hvu-047281	Hordeum vulgare	70.47	2.00e-83	300.00
IUUC-Itr-048739	Ictidomys tridecemlineatus	64.74	3.00e-58	217.00
IUUC-Lch-049415	Latimeria chalumnae	71.43	1.00e-43	167.00
IUUC-Lpe-050956	Leersia perrieri	62.11	2.00e-70	257.00
IUUC-Lma-052996	Leptosphaeria maculans	51.38	4.00e-31	128.00
IUUC-Laf-053337	Loxodonta africana	65.33	6.00e-58	216.00
IUUC-Mcc-055485	Macaca mulatta	52.74	5.00e-55	206.00
IUUC-Meu-056123	Macropus eugenii	63.33	9.00e-57	212.00
IUUC-Mtr-058300	Medicago truncatula	84.92	5.00e-93	333.00
IUUC-Mla-059060	Melampsora laricipopulina	50.66	8.00e-46	175.00
IUUC-Mmr-061005	Microcebus murinus	65.16	2.00e-58	218.00
IUUC-Mdo-062979	Monodelphis domestica	65.60	4.00e-48	183.00
IUUC-Mmu-063778	Mus musculus	64.74	4.00e-58	216.00
IUUC-Mac-065490	Musa acuminata	72.73	3.00e-92	331.00
IUUC-Mpu-065829	Mustela putorius furo	64.74	8.00e-59	219.00
IUUC-Mlu-067498	Myotis lucifugus	64.29	3.00e-53	200.00
IUUC-Nfi-068520	Neosartorya fischeri	49.23	1.00e-34	140.00
IUUC-Nle-069727	Nomascus leucogenys	64.74	5.00e-59	219.00
IUUC-Opr-071066	Ochotona princeps	65.49	3.00e-41	159.00
IUUC-Ont-072363	Oreochromis niloticus	58.55	5.00e-52	196.00
IUUC-Oan-073383	Ornithorhynchus anatinus	68.57	3.00e-42	163.00
IUUC-Ocu-074599	Oryctolagus cuniculus	66.17	6.00e-52	196.00
IUUC-Oba-075186	Oryza barthii	68.22	6.00e-87	313.00
IUUC-Obr-076104	Oryza brachyantha	68.36	4.00e-86	310.00
IUUC-Ogl-077835	Oryza glaberrima	68.22	6.00e-87	312.00
IUUC-Ogu-078690	Oryza glumaepatula	68.22	6.00e-87	312.00
IUUC-Oin-080215	Oryza indica	68.22	6.00e-87	313.00
IUUC-Olo-080816	Oryza longistaminata	68.22	7.00e-87	313.00
IUUC-Ome-081657	Oryza meridionalis	68.22	1.00e-86	312.00
IUUC-Oni-082601	Oryza nivara	68.22	5.00e-87	313.00
IUUC-Opu-083367	Oryza punctata	68.22	2.00e-86	311.00
IUUC-Oru-084477	Oryza rufipogon	68.22	4.00e-87	313.00
IUUC-Osa-086119	Oryza sativa	68.22	5.00e-87	313.00
IUUC-Ola-086702	Oryzias latipes	58.97	1.00e-53	202.00
IUUC-Olu-087576	Ostreococcus lucimarinus	60.00	4.00e-57	213.00
IUUC-Oga-088946	Otolemur garnettii	63.87	8.00e-59	219.00
IUUC-Oar-089564	Ovis aries	64.90	5.00e-58	216.00
IUUC-Ptr-090620	Pan troglodytes	60.23	8.00e-59	219.00
IUUC-Pan-092382	Papio anubis	52.74	6.00e-55	206.00
IUUC-Psi-093891	Pelodiscus sinensis	62.83	6.00e-40	154.00
IUUC-Pma-094344	Petromyzon marinus	64.67	6.00e-58	216.00
IUUC-Pno-094981	Phaeosphaeria nodorum	49.55	1.00e-27	116.00
IUUC-Ppa-095452	Physcomitrella patens	58.66	4.00e-66	243.00
IUUC-Pfo-097288	Poecilia formosa	57.83	7.00e-55	206.00
IUUC-Pab-098506	Pongo abelii	60.23	6.00e-59	219.00
IUUC-Pop-098882	Populus trichocarpa	70.90	4.00e-106	376.00
IUUC-Pca-100749	Procavia capensis	65.16	2.00e-58	218.00
IUUC-Ppe-102084	Prunus persica	77.63	1.00e-97	348.00
IUUC-Pva-102755	Pteropus vampyrus	64.74	1.00e-58	218.00
IUUC-Pgr-103394	Puccinia graminis	52.90	6.00e-47	180.00
IUUC-Ptt-103750	Puccinia triticina	52.26	5.00e-47	180.00
IUUC-Pte-104240	Pyrenophora teres	47.06	6.00e-28	117.00
IUUC-Pyt-104483	Pyrenophora triticirepentis	47.06	5.00e-28	117.00
IUUC-Rno-105739	Rattus norvegicus	64.74	1.00e-58	218.00
IUUC-Smo-108939	Selaginella moellendorffii	60.00	5.00e-67	246.00
IUUC-Sit-109881	Setaria italica	77.14	6.00e-83	299.00
IUUC-Sly-111764	Solanum lycopersicum	71.48	1.00e-103	368.00
IUUC-Stu-111968	Solanum tuberosum	71.86	6.00e-104	369.00
IUUC-Sar-113093	Sorex araneus	64.76	8.00e-36	142.00
IUUC-Sbi-114015	Sorghum bicolor	69.14	5.00e-88	316.00
IUUC-Sre-115036	Sporisorium reilianum	43.42	2.00e-33	134.00
IUUC-Tru-117716	Takifugu rubripes	58.43	8.00e-55	206.00
IUUC-Tni-120210	Tetraodon nigroviridis	58.39	7.00e-55	206.00
IUUC-Tca-121315	Theobroma cacao	71.91	6.00e-106	375.00
IUUC-Tae-125572	Triticum aestivum	70.43	7.00e-88	315.00
IUUC-Tur-126669	Triticum urartu	67.98	2.00e-83	301.00
IUUC-Tme-127125	Tuber melanosporum	42.19	4.00e-38	150.00
IUUC-Tbe-128157	Tupaia belangeri	66.00	2.00e-58	217.00
IUUC-Ttr-128593	Tursiops truncatus	63.46	6.00e-56	209.00
IUUC-Uma-129592	Ustilago maydis	40.00	2.00e-38	150.00
IUUC-Vvi-131716	Vitis vinifera	74.13	2.00e-107	380.00
IUUC-Xtr-132592	Xenopus tropicalis	63.69	4.00e-60	223.00
IUUC-Xma-133064	Xiphophorus maculatus	56.10	3.00e-48	184.00
IUUC-Yli-134575	Yarrowia lipolytica	46.53	3.00e-35	140.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence