iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-068208

Ensembl Protein ID

ENSMLUP00000005705.2

UniProt Accession

G1P6K8; G1P6K8_MYOLU

Genbank Protein ID

ENSMLUP00000005705

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02030767

Gene Name

TRIM37

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000006229.2	ENSMLUT00000006247.2	ENSMLUP00000005705.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	92.24	0.00e+00	1603.00	IUUC-Hsa-046400
E3 activity/RING/RING	90.16	0.00e+00	1583.00	IUUC-Mmu-064161

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MDEQSVESIA EVFRCFICME KLRDARLCPH CSKLCCFSCI RRWLTEQRAQ CPHCRAPLQI 60
RELVNCRWAE EVTQQLDTLQ LCSLTKHEEN EKDKCENHHE KLSVFCWTCK KCICHQCALW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATGAAC AGAGTGTAGA GGTGAGGAGG TTTGAGGAGG TTGGTGGTTC GTGTCCCCAT 60
GCTACCCGCT GAGTGTTTTT TTAAGCGGGT CGCCTTTCCC TAGTCCTCTC CGGTAGGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003649--Bbox_C
IPR002083--MATH/TRAF_dom
IPR008974--TRAF-like
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50144--MATH
PS50119--ZF_BBOX
PS50089--ZF_RING_2

Pfam

PF00917--MATH
PF00643--zf-B_box

SMART

SM00502--BBC
SM00336--BBOX
SM00061--MATH

Gene Ontology

GO:0016235--C:aggresome
GO:0005829--C:cytosol
GO:0035098--C:ESC/E(Z) complex
GO:0005777--C:peroxisome
GO:0003682--F:chromatin binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0070842--P:aggresome assembly
GO:0036353--P:histone H2A-K119 monoubiquitination
GO:0046600--P:negative regulation of centriole replication
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0051865--P:protein autoubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002402	Ailuropoda melanoleuca	93.26	0.00e+00	1617.00
IUUC-Apl-003421	Anas platyrhynchos	78.48	0.00e+00	1285.00
IUUC-Aca-004895	Anolis carolinensis	74.49	0.00e+00	1234.00
IUUC-Aly-005536	Arabidopsis lyrata	30.00	2.00e-08	53.50
IUUC-Ath-007082	Arabidopsis thaliana	29.46	1.00e-08	53.90
IUUC-Ame-011010	Astyanax mexicanus	70.81	0.00e+00	980.00
IUUC-Bta-012395	Bos taurus	91.50	0.00e+00	1464.00
IUUC-Bol-016312	Brassica oleracea	31.01	4.00e-08	52.80
IUUC-Cja-019077	Callithrix jacchus	91.42	0.00e+00	1584.00
IUUC-Cfa-020944	Canis familiaris	92.23	0.00e+00	1549.00
IUUC-Cpo-021701	Cavia porcellus	87.78	0.00e+00	1526.00
IUUC-Csa-023468	Chlorocebus sabaeus	91.73	0.00e+00	1593.00
IUUC-Cho-024941	Choloepus hoffmanni	83.83	0.00e+00	792.00
IUUC-Cin-025184	Ciona intestinalis	71.47	2.00e-171	595.00
IUUC-Csv-026304	Ciona savignyi	64.29	2.00e-59	221.00
IUUC-Dre-027580	Danio rerio	62.02	0.00e+00	993.00
IUUC-Dno-029665	Dasypus novemcinctus	89.76	0.00e+00	1433.00
IUUC-Dor-030509	Dipodomys ordii	66.35	0.00e+00	670.00
IUUC-Ete-032665	Echinops telfairi	74.43	4.00e-166	578.00
IUUC-Eca-034388	Equus caballus	93.16	0.00e+00	1590.00
IUUC-Eeu-034530	Erinaceus europaeus	50.80	2.00e-79	290.00
IUUC-Fca-035842	Felis catus	93.78	0.00e+00	1625.00
IUUC-Fal-037490	Ficedula albicollis	91.13	0.00e+00	939.00
IUUC-Gmo-039700	Gadus morhua	96.84	7.00e-94	337.00
IUUC-Gga-040199	Gallus gallus	76.98	0.00e+00	1279.00
IUUC-Gac-041724	Gasterosteus aculeatus	73.44	0.00e+00	919.00
IUUC-Gma-043466	Glycine max	30.43	7.00e-08	50.80
IUUC-Ggo-045389	Gorilla gorilla	89.29	0.00e+00	1402.00
IUUC-Hsa-046400	Homo sapiens	92.24	0.00e+00	1592.00
IUUC-Itr-048382	Ictidomys tridecemlineatus	90.58	0.00e+00	1556.00
IUUC-Lch-049653	Latimeria chalumnae	68.64	0.00e+00	1073.00
IUUC-Loc-051900	Lepisosteus oculatus	62.69	0.00e+00	991.00
IUUC-Laf-053606	Loxodonta africana	92.56	0.00e+00	1580.00
IUUC-Mcc-054607	Macaca mulatta	92.04	0.00e+00	1598.00
IUUC-Meu-056746	Macropus eugenii	89.26	0.00e+00	780.00
IUUC-Mga-060028	Meleagris gallopavo	77.80	0.00e+00	1275.00
IUUC-Mmr-061345	Microcebus murinus	91.40	0.00e+00	1561.00
IUUC-Mdo-062615	Monodelphis domestica	82.77	0.00e+00	1404.00
IUUC-Mmu-064161	Mus musculus	90.05	0.00e+00	1543.00
IUUC-Mac-065602	Musa acuminata	28.26	3.00e-07	49.30
IUUC-Mpu-066437	Mustela putorius furo	92.03	0.00e+00	1581.00
IUUC-Nle-069104	Nomascus leucogenys	91.13	0.00e+00	1553.00
IUUC-Opr-070233	Ochotona princeps	98.68	1.00e-89	324.00
IUUC-Ont-071969	Oreochromis niloticus	84.10	0.00e+00	873.00
IUUC-Oan-072914	Ornithorhynchus anatinus	70.13	0.00e+00	708.00
IUUC-Ocu-074943	Oryctolagus cuniculus	90.06	0.00e+00	1528.00
IUUC-Oga-088371	Otolemur garnettii	90.17	0.00e+00	1577.00
IUUC-Oar-090383	Ovis aries	91.61	0.00e+00	1508.00
IUUC-Ptr-091450	Pan troglodytes	92.14	0.00e+00	1600.00
IUUC-Pan-091800	Papio anubis	87.92	0.00e+00	937.00
IUUC-Psi-093665	Pelodiscus sinensis	92.79	0.00e+00	918.00
IUUC-Pma-094559	Petromyzon marinus	75.78	0.00e+00	799.00
IUUC-Ppa-095483	Physcomitrella patens	41.59	3.00e-92	333.00
IUUC-Pfo-097163	Poecilia formosa	60.25	4.00e-134	471.00
IUUC-Pab-098742	Pongo abelii	92.10	0.00e+00	1556.00
IUUC-Pop-099648	Populus trichocarpa	31.39	9.00e-07	47.40
IUUC-Pca-100656	Procavia capensis	76.65	0.00e+00	742.00
IUUC-Ppe-101374	Prunus persica	31.06	1.00e-09	57.40
IUUC-Pva-103231	Pteropus vampyrus	81.09	0.00e+00	1152.00
IUUC-Rno-105564	Rattus norvegicus	90.05	0.00e+00	1566.00
IUUC-Smo-109220	Selaginella moellendorffii	36.60	1.00e-87	317.00
IUUC-Sar-112934	Sorex araneus	83.89	0.00e+00	714.00
IUUC-Ssc-116278	Sus scrofa	88.96	0.00e+00	931.00
IUUC-Tgu-117396	Taeniopygia guttata	91.46	0.00e+00	952.00
IUUC-Tru-118296	Takifugu rubripes	74.47	0.00e+00	932.00
IUUC-Tsy-119188	Tarsius syrichta	88.13	0.00e+00	729.00
IUUC-Tni-120147	Tetraodon nigroviridis	73.60	0.00e+00	919.00
IUUC-Tbe-127682	Tupaia belangeri	87.85	0.00e+00	717.00
IUUC-Ttr-129176	Tursiops truncatus	99.32	0.00e+00	860.00
IUUC-Vpa-130336	Vicugna pacos	85.17	0.00e+00	1320.00
IUUC-Vvi-131514	Vitis vinifera	34.88	9.00e-08	50.80
IUUC-Xtr-132646	Xenopus tropicalis	64.74	0.00e+00	1074.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence