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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Cel-018132
UUCD1 version UUC-CaE-00737
Ensembl Protein ID F38A5.1a
UniProt Accession Q94218; Q86MF8; UFSP_CAEEL
Genbank Protein ID CCD67166.1; CCD67167.1
Protein Name Ufm1-specific protease; Odorant response abnormal protein 8
Genbank Nucleotide ID FO080844; FO080844
Gene Name odr-8; ufsp-2; F38A5.1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
WBGene00018160 F38A5.1a F38A5.1a
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNARAID2
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
DUB/ULP 50.71 1.00e-81 301.00 IUUC-Hsa-046929
Active Site
Position(s) Description Evidence
421 N/A {ECO:0000250}
545 {ECO:0000250}
547 {ECO:0000250}
Organism Caenorhabditis elegans
Functional Description
(View)

Functional Description


     Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ufm-1, a ubiquitin-like modifier protein bound to a number of target proteins (By similarity). Required, with oct-4, for the localization of a subset of 7 transmembrane domain odorant receptors, including odr-10, to the cilia of olfactory neurons AWA and AWC. Operates in aggregation behavior, and responses to oxygen levels.
 Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ufm-1, a ubiquitin-like modifier protein bound to a number of target proteins (By similarity). Required, with oct-4, for the localization of a subset of 7 transmembrane domain odorant receptors, including odr-10, to the cilia of olfactory neurons AWA and AWC. Operates in aggregation behavior, and responses to oxygen levels.
Protein Sequence
(Fasta)
MTNSQTVSLI GPTQMAPQST PPPPVNELWF IDAQAMFQNY ANLRSFSKSN ANEINTTIGG 60
FVFGRKARKQ VIHVLFAYAE DLTESNRQFL ESSLSADIEL VGNLNIDGQS QILPGGQFTL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cel-018132|DUB,ULP|Caenorhabditis elegans
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TTGGAAGAGA AGAAGAATGA CGAATTCTCA AACTGTCTCA CTAATTGGAC CAACTCAGAT 60
GGCTCCACAA TCAACACCTC CACCTCCTGT GAATGAATTG TGGTTTATTG ATGCGCAGGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cel-018132|DUB,ULP|Caenorhabditis elegans
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0025--Alternative splicing
KW-0145--Chemotaxis
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0256--Endoplasmic reticulum
KW-0378--Hydrolase
KW-0472--Membrane
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
Interpro

IPR012462--Peptidase_C78_UfSP1/2
Pfam

PF07910--Peptidase_C78
Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0048471--C:perinuclear region of cytoplasm
GO:0043234--C:protein complex
GO:0071567--F:UFM1 hydrolase activity
GO:0006935--P:chemotaxis
GO:0050921--P:positive regulation of chemotaxis
GO:0097499--P:protein localization to non-motile cilium
GO:0045471--P:response to ethanol
KEGG cel:CELE_F38A5.1
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000578 Aegilops tauschii 53.33 2.00e-72 264.00
IUUC-Aml-001757 Ailuropoda melanoleuca 50.71 4.00e-83 300.00
IUUC-Atr-002641 Amborella trichopoda 47.70 1.00e-71 263.00
IUUC-Apl-003911 Anas platyrhynchos 46.29 2.00e-75 275.00
IUUC-Aca-005294 Anolis carolinensis 49.64 3.00e-81 294.00
IUUC-Aly-006185 Arabidopsis lyrata 53.74 1.00e-69 256.00
IUUC-Ath-006919 Arabidopsis thaliana 51.95 2.00e-70 258.00
IUUC-Ani-009145 Aspergillus nidulans 45.00 6.10e+00 25.40
IUUC-Ame-011931 Astyanax mexicanus 48.69 1.00e-76 278.00
IUUC-Bta-012389 Bos taurus 51.49 1.00e-81 295.00
IUUC-Bdi-014306 Brachypodium distachyon 46.64 8.00e-70 256.00
IUUC-Bol-016591 Brassica oleracea 57.58 9.00e-70 256.00
IUUC-Bra-017122 Brassica rapa 45.07 1.00e-61 229.00
IUUC-Cja-019735 Callithrix jacchus 50.00 3.00e-81 294.00
IUUC-Cfa-020814 Canis familiaris 40.15 9.00e-84 302.00
IUUC-Cpo-021576 Cavia porcellus 50.71 1.00e-82 298.00
IUUC-Cre-022668 Chlamydomonas reinhardtii 53.85 1.00e-62 230.00
IUUC-Csa-023368 Chlorocebus sabaeus 50.00 1.00e-82 298.00
IUUC-Cho-024731 Choloepus hoffmanni 44.64 6.00e-69 253.00
IUUC-Cin-025359 Ciona intestinalis 53.31 1.00e-81 295.00
IUUC-Csv-025886 Ciona savignyi 55.98 1.00e-71 260.00
IUUC-Dre-027673 Danio rerio 40.88 1.00e-75 275.00
IUUC-Dno-030101 Dasypus novemcinctus 49.11 3.00e-80 291.00
IUUC-Dor-030612 Dipodomys ordii 51.13 4.00e-80 290.00
IUUC-Dme-032198 Drosophila melanogaster 50.21 3.00e-65 241.00
IUUC-Ete-032738 Echinops telfairi 59.79 2.00e-72 265.00
IUUC-Eca-034093 Equus caballus 50.35 2.00e-83 301.00
IUUC-Eeu-034624 Erinaceus europaeus 48.30 8.00e-80 289.00
IUUC-Fca-035542 Felis catus 43.99 3.00e-84 304.00
IUUC-Fal-036770 Ficedula albicollis 49.82 3.00e-83 300.00
IUUC-Gmo-039601 Gadus morhua 48.31 2.00e-75 275.00
IUUC-Gga-040670 Gallus gallus 50.71 1.00e-84 305.00
IUUC-Gac-042013 Gasterosteus aculeatus 41.06 5.00e-76 276.00
IUUC-Gma-043320 Glycine max 46.90 3.00e-75 275.00
IUUC-Ggo-045051 Gorilla gorilla 50.71 2.00e-83 301.00
IUUC-Hsa-046929 Homo sapiens 50.71 2.00e-83 301.00
IUUC-Itr-047967 Ictidomys tridecemlineatus 52.40 2.00e-82 298.00
IUUC-Lch-049884 Latimeria chalumnae 40.66 3.00e-77 281.00
IUUC-Lpe-051425 Leersia perrieri 53.85 7.00e-74 270.00
IUUC-Loc-052568 Lepisosteus oculatus 51.30 3.00e-78 284.00
IUUC-Laf-053435 Loxodonta africana 50.18 3.00e-82 297.00
IUUC-Mcc-055106 Macaca mulatta 50.35 4.00e-83 300.00
IUUC-Mtr-057740 Medicago truncatula 48.76 3.00e-77 281.00
IUUC-Mga-060094 Meleagris gallopavo 50.71 5.00e-84 303.00
IUUC-Mmr-061634 Microcebus murinus 51.06 6.00e-84 303.00
IUUC-Mdo-062862 Monodelphis domestica 49.82 5.00e-81 293.00
IUUC-Mmu-063729 Mus musculus 52.06 5.00e-82 296.00
IUUC-Mac-065086 Musa acuminata 46.85 1.00e-69 256.00
IUUC-Mpu-066461 Mustela putorius furo 51.77 3.00e-84 304.00
IUUC-Mlu-067443 Myotis lucifugus 50.00 6.00e-81 293.00
IUUC-Nle-069354 Nomascus leucogenys 50.71 2.00e-83 301.00
IUUC-Opr-070818 Ochotona princeps 56.20 3.00e-78 284.00
IUUC-Ont-072430 Oreochromis niloticus 43.40 2.00e-81 294.00
IUUC-Oan-072972 Ornithorhynchus anatinus 57.65 3.00e-71 259.00
IUUC-Ocu-074052 Oryctolagus cuniculus 50.89 4.00e-83 300.00
IUUC-Oba-075331 Oryza barthii 59.04 1.00e-69 256.00
IUUC-Obr-076810 Oryza brachyantha 54.50 1.00e-72 266.00
IUUC-Ogl-077185 Oryza glaberrima 59.04 1.00e-69 256.00
IUUC-Ogu-078014 Oryza glumaepatula 59.04 1.00e-69 256.00
IUUC-Oin-080170 Oryza indica 59.04 1.00e-69 256.00
IUUC-Olo-080561 Oryza longistaminata 58.73 9.00e-70 256.00
IUUC-Ome-081878 Oryza meridionalis 59.04 8.00e-70 256.00
IUUC-Oni-083106 Oryza nivara 59.04 1.00e-69 256.00
IUUC-Opu-083384 Oryza punctata 54.17 5.00e-71 260.00
IUUC-Oru-085240 Oryza rufipogon 59.04 9.00e-70 256.00
IUUC-Osa-086230 Oryza sativa 59.04 7.00e-70 256.00
IUUC-Ola-087525 Oryzias latipes 41.95 3.00e-73 267.00
IUUC-Oga-088657 Otolemur garnettii 49.29 5.00e-83 300.00
IUUC-Oar-089494 Ovis aries 50.00 8.00e-83 299.00
IUUC-Ptr-091189 Pan troglodytes 50.71 2.00e-83 301.00
IUUC-Pan-092071 Papio anubis 51.06 7.00e-84 303.00
IUUC-Psi-092991 Pelodiscus sinensis 51.24 2.00e-84 305.00
IUUC-Pma-094182 Petromyzon marinus 51.80 4.00e-44 168.00
IUUC-Ppa-095743 Physcomitrella patens 50.40 4.00e-70 258.00
IUUC-Pfo-096271 Poecilia formosa 46.01 6.00e-79 286.00
IUUC-Pab-097928 Pongo abelii 48.59 9.00e-75 272.00
IUUC-Pop-098826 Populus trichocarpa 47.22 9.00e-74 270.00
IUUC-Pca-100279 Procavia capensis 38.62 8.00e-82 296.00
IUUC-Ppe-101401 Prunus persica 45.55 2.00e-70 259.00
IUUC-Pva-102713 Pteropus vampyrus 37.85 3.00e-76 278.00
IUUC-Rno-105697 Rattus norvegicus 49.82 4.00e-82 296.00
IUUC-Sha-106956 Sarcophilus harrisii 48.76 5.00e-82 297.00
IUUC-Smo-109070 Selaginella moellendorffii 43.67 7.00e-75 273.00
IUUC-Sit-109821 Setaria italica 49.63 2.00e-73 268.00
IUUC-Sly-110903 Solanum lycopersicum 49.30 4.00e-76 277.00
IUUC-Stu-111930 Solanum tuberosum 49.12 4.00e-76 277.00
IUUC-Sar-113264 Sorex araneus 49.65 6.00e-82 296.00
IUUC-Sbi-114732 Sorghum bicolor 41.95 1.00e-54 206.00
IUUC-Ssc-115435 Sus scrofa 50.19 5.00e-73 267.00
IUUC-Tgu-116761 Taeniopygia guttata 53.53 6.00e-78 282.00
IUUC-Tru-118435 Takifugu rubripes 36.90 4.00e-75 274.00
IUUC-Tsy-119445 Tarsius syrichta 48.21 3.00e-79 287.00
IUUC-Tni-119948 Tetraodon nigroviridis 56.10 3.00e-70 256.00
IUUC-Tca-121332 Theobroma cacao 49.43 2.00e-73 269.00
IUUC-Tae-123925 Triticum aestivum 48.41 2.00e-73 268.00
IUUC-Tur-126833 Triticum urartu 52.40 3.00e-70 258.00
IUUC-Tbe-127826 Tupaia belangeri 36.57 3.00e-71 261.00
IUUC-Ttr-129116 Tursiops truncatus 52.92 6.00e-80 290.00
IUUC-Vpa-130588 Vicugna pacos 49.65 7.00e-78 283.00
IUUC-Vvi-130898 Vitis vinifera 47.18 7.00e-75 273.00
IUUC-Xtr-132571 Xenopus tropicalis 51.17 2.00e-79 288.00
IUUC-Xma-133755 Xiphophorus maculatus 49.82 1.00e-77 282.00
Created Date 25-Jun-2017

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