iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Itr-048680

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01010820

Gene Name

CUL9

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000014226.2	ENSSTOT00000014239.2	ENSSTOP00000012755.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/Cullin	1.10e-128	430.6	1296	1816

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/Cullin

   S: 66   LktynreWekfreqlkvlrkifayldrtyvkkskkvsevrkLaldlwrkeivedikkrllelllklieaeRkgeavdrrllsgvves 152
           L    ++W+ freql++ +++f      y+ +           +++w+++i+ed +krll+l+ +l++ +R+++++++r+l++++++
   Q: 1296 LGPKPTFWPLFREQLCRRTCLF------YTIR-----------AQAWSRDIAED-RKRLLQLCPRLNRVLRHEQNFADRFLPDDEAA 1364
           5555689***************......9999...........***********.******************************** PP
   S: 153  lveLslnklaiykesFEakfleatqefykaesaeflqe.nevdeYlkkvearlneeeeraaryleestetkLlevvekeliakhles 238
                   +a++k+++Ea++++ +q+++ ++++ +++  + +d+Yl+++e++  + +++a+++++++++++Ll++ e+   +     
   Q: 1365 --------QALGKTCWEALVSPLVQNITLPDAEGVSSLgWLLDQYLEQRENSQIPMSRAASFASRVRRLCHLLVHAEPPPGP----- 1438
           ........**************************************************************************..... PP
   S: 239  llaelvallrdkktedlsrmykLlsrvln..gleellkeleshikeqgkaaltaeekekdpkkyVerllelknklqklvseaFnnda 323
             ++ + +   +k++++++ + + s vl+  +l+++++++ s+++eq++++l+a++++ d   +V+r+++l+++lq++ se+F+ +a
   Q: 1439 --SPEPLTRPFSKNSKVRDRSPVPSPVLPssSLRNITQCWLSVVQEQVSRFLAAAWRAPD---FVPRYCKLYEHLQRAGSELFGSRA 1520
           ..9**************************99*****************************...************************ PP
   S: 324  kFlkaldkafetfvnknsvlkaakspEllAryiDqlLrks.skglteeeleaqldkvllvfkyisekdv...FekyYkkhLakRLls 406
           +F+ al+++f+ +++++s+l+aa+++E++Ar+ Dq+++++  +g  + e++ ql+++l+ ++++s++++   Fe++Y++++a+RLls
   Q: 1521 AFTLALRSGFSGALLQQSFLTAAHMSEQFARHLDQQIQGNlFGGSPGVEMLGQLQQHLEPIMVLSGLELattFEHFYQHYMADRLLS 1607
           *************************************************************************************** PP
   S: 407  gksasseaEesviekLkeecgaeftskL.erMfqdlkvSedlnrqFk...............................eekentees 461
               s ++E++v+e++    g++f+++L ++M+++l++Se+l+rqF+                               + ke   e+
   Q: 1608 --LGSTWLEGAVLEQI----GLCFPNRLpQQMLRSLSTSEELQRQFHlfqlqqldrllleqedeeeleeegeeeeeeeAGKEIFMED 1688
           ..**************....*****************************************************99876667778899 PP
   S: 462  esvelsvlvLsagaWpta..set..ekvsLPaelektiekfeefY........lekhsgRkLqWqhtlgraelkaelkkgkyelqVs 536
           +s+++s+lvLs+++Wp++  +    ++ +LP+e++++++ f++fY        l+++++R+LqW++ lgrael++    g ++l+Vs
   Q: 1689 PSPTVSILVLSPRCWPVSplCYLhhPRKCLPTEFCDALDCFSSFYsqsqnhpvLDMGPHRRLQWTW-LGRAELQF----GDQTLHVS 1770
           ******************9855455*****************************************.********....******** PP
   S: 537  tfQmavLLafnnsekvsveelkkatelpeeeLrrtlqsLvsskkqv 582
           t+Qm++LL fn+ e+vs+e+l k ++l++e+L+++l +L+s +  +
   Q: 1771 TVQMWLLLNFNQIEEVSIETLLKNSDLSAELLHQALLPLTSENGPL 1816
           ****************************************977444 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MIGERRARGL MVPLGPQLQA YPEELIRQRP GHDGHPEYLV RWSVLKCGEV SKVGVEEGKA 60
EHILMWLSAP EVYANCPMLL GERALSKGPQ HEPSGGSGSF PRDPGGLDDV AMGEMEADVR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGATAGGGG AACGGCGTGC TAGGGGCCTT ATGGTGCCCT TGGGGCCCCA GCTGCAGGCA 60
TATCCTGAAG AACTTATTCG ACAGCGGCCT GGACATGATG GACACCCTGA ATACCTGGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR004939--APC_su10/DOC_dom
IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR016150--Casein_kin_II_reg-sub_b-sht
IPR021097--CPH_domain
IPR031222--CUL9
IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR008979--Galactose-bd-like
IPR002867--IBR_dom
IPR014722--Rib_L2_dom2
IPR011991--WHTH_DNA-bd_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2
PS51284--DOC
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF03256--ANAPC10
PF11515--Cul7
PF00888--Cullin
PF10557--Cullin_Nedd8
PF01485--IBR

SMART

SM01337--APC10
SM00884--Cullin_Nedd8
SM00647--IBR

Gene Ontology

GO:0031461--C:cullin-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0008270--F:zinc ion binding
GO:0000226--P:microtubule cytoskeleton organization
GO:0016567--P:protein ubiquitination
GO:0007088--P:regulation of mitotic nuclear division
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001405	Ailuropoda melanoleuca	90.10	0.00e+00	4325.00
IUUC-Apl-003458	Anas platyrhynchos	64.11	0.00e+00	763.00
IUUC-Aca-004815	Anolis carolinensis	56.40	0.00e+00	2546.00
IUUC-Ame-010611	Astyanax mexicanus	51.07	0.00e+00	2271.00
IUUC-Bta-012877	Bos taurus	87.44	0.00e+00	4064.00
IUUC-Cja-019255	Callithrix jacchus	90.53	0.00e+00	4239.00
IUUC-Cfa-020119	Canis familiaris	90.33	0.00e+00	4306.00
IUUC-Cpo-022473	Cavia porcellus	83.69	0.00e+00	3827.00
IUUC-Csa-024157	Chlorocebus sabaeus	90.31	0.00e+00	4224.00
IUUC-Cho-024879	Choloepus hoffmanni	86.25	0.00e+00	919.00
IUUC-Cin-025402	Ciona intestinalis	31.79	0.00e+00	726.00
IUUC-Dno-028904	Dasypus novemcinctus	87.32	0.00e+00	4089.00
IUUC-Dor-030112	Dipodomys ordii	88.00	0.00e+00	1358.00
IUUC-Ete-032516	Echinops telfairi	79.36	0.00e+00	1332.00
IUUC-Eca-034394	Equus caballus	90.24	0.00e+00	4153.00
IUUC-Eeu-035166	Erinaceus europaeus	87.25	0.00e+00	2155.00
IUUC-Fca-035740	Felis catus	90.07	0.00e+00	4235.00
IUUC-Fal-036672	Ficedula albicollis	51.29	0.00e+00	1543.00
IUUC-Gga-040154	Gallus gallus	61.02	0.00e+00	905.00
IUUC-Ggo-045570	Gorilla gorilla	90.24	0.00e+00	4181.00
IUUC-Hsa-046690	Homo sapiens	90.35	0.00e+00	4173.00
IUUC-Loc-052706	Lepisosteus oculatus	52.11	0.00e+00	2357.00
IUUC-Mcc-055727	Macaca mulatta	90.47	0.00e+00	4270.00
IUUC-Meu-056074	Macropus eugenii	74.82	0.00e+00	1496.00
IUUC-Mga-059683	Meleagris gallopavo	52.87	1.00e-100	359.00
IUUC-Mmr-060869	Microcebus murinus	91.12	0.00e+00	4284.00
IUUC-Mdo-062902	Monodelphis domestica	73.41	0.00e+00	3310.00
IUUC-Mmu-063991	Mus musculus	85.69	0.00e+00	3998.00
IUUC-Mpu-065974	Mustela putorius furo	89.70	0.00e+00	4243.00
IUUC-Nle-069292	Nomascus leucogenys	90.86	0.00e+00	2697.00
IUUC-Opr-071020	Ochotona princeps	86.68	0.00e+00	2167.00
IUUC-Ont-071953	Oreochromis niloticus	51.33	0.00e+00	2197.00
IUUC-Oan-073534	Ornithorhynchus anatinus	59.21	0.00e+00	2082.00
IUUC-Ocu-074244	Oryctolagus cuniculus	88.37	0.00e+00	4171.00
IUUC-Ola-087072	Oryzias latipes	51.61	0.00e+00	2236.00
IUUC-Oga-088310	Otolemur garnettii	87.63	0.00e+00	4200.00
IUUC-Oar-090174	Ovis aries	87.31	0.00e+00	4018.00
IUUC-Ptr-091410	Pan troglodytes	90.47	0.00e+00	4162.00
IUUC-Pan-091856	Papio anubis	91.24	0.00e+00	2692.00
IUUC-Pma-094192	Petromyzon marinus	46.12	0.00e+00	1423.00
IUUC-Pfo-096773	Poecilia formosa	55.78	0.00e+00	957.00
IUUC-Pab-098635	Pongo abelii	90.43	0.00e+00	2904.00
IUUC-Pca-100539	Procavia capensis	88.89	0.00e+00	1365.00
IUUC-Pva-102813	Pteropus vampyrus	86.47	0.00e+00	1682.00
IUUC-Rno-106105	Rattus norvegicus	86.07	0.00e+00	4033.00
IUUC-Sha-106896	Sarcophilus harrisii	76.43	0.00e+00	1178.00
IUUC-Ssl-108406	Sclerotinia sclerotiorum	27.80	3.00e-08	52.80
IUUC-Sar-113132	Sorex araneus	80.05	0.00e+00	1269.00
IUUC-Ssc-116000	Sus scrofa	88.88	0.00e+00	4156.00
IUUC-Tgu-116915	Taeniopygia guttata	62.27	4.00e-138	484.00
IUUC-Tru-118013	Takifugu rubripes	55.35	0.00e+00	1564.00
IUUC-Tsy-119037	Tarsius syrichta	82.02	0.00e+00	1115.00
IUUC-Tni-120062	Tetraodon nigroviridis	51.34	0.00e+00	2265.00
IUUC-Ttr-128780	Tursiops truncatus	85.18	0.00e+00	2644.00
IUUC-Vpa-130086	Vicugna pacos	83.08	0.00e+00	664.00
IUUC-Xtr-132882	Xenopus tropicalis	50.40	0.00e+00	1843.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence