iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	Mentha
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	36.16	5.00e-94	342.00	IUUC-Hsa-045801

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Caenorhabditis elegans

Functional Description
(View)

Acts as an E3 ubiquitin-protein ligase.

Protein Sequence
(Fasta)

MNEYGCNVCN EEYSARDPLK CPRVLTGCGH TICHNCAISI AGRNSSIFCP FDRTATQIPG 60
GDLQNLKKNF ALLELLEKIA DGGGLLEKSG EVVKFDRYSK ERLLNLECDE DSEHVAVIYC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTAATGAATG AATATGGTTG CAACGTGTGC AACGAGGAGT ATTCGGCACG GGATCCTTTG 60
AAATGTCCAC GTGTTTTGAC GGGTTGCGGC CATACAATTT GCCACAATTG TGCCATATCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0342--GTP-binding
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003649--Bbox_C
IPR027417--P-loop_NTPase
IPR005225--Small_GTP-bd_dom
IPR024156--Small_GTPase_ARF
IPR006689--Small_GTPase_ARF/SAR
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR013087--Znf_C2H2_type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51417--ARF
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00025--Arf
PF00643--zf-B_box
PF13445--zf-RING_UBOX

PRINTS

PR00328--SAR1GTPBP

SMART

SM00502--BBC
SM00336--BBOX
SM00184--RING

Gene Ontology

GO:0005622--C:intracellular
GO:0005525--F:GTP binding
GO:0016740--F:transferase activity
GO:0008270--F:zinc ion binding
GO:0016567--P:protein ubiquitination
GO:0007264--P:small GTPase mediated signal transduction

KEGG

cel:CELE_ZK1320.6

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001685	Ailuropoda melanoleuca	36.51	1.00e-93	335.00
IUUC-Apl-003280	Anas platyrhynchos	36.33	2.00e-95	342.00
IUUC-Aca-004587	Anolis carolinensis	37.30	2.00e-85	308.00
IUUC-Ame-010760	Astyanax mexicanus	36.46	2.00e-95	342.00
IUUC-Bta-013139	Bos taurus	36.28	1.00e-95	342.00
IUUC-Cja-019407	Callithrix jacchus	36.28	2.00e-94	338.00
IUUC-Cfa-020758	Canis familiaris	36.65	6.00e-95	340.00
IUUC-Cpo-022050	Cavia porcellus	36.16	1.00e-95	342.00
IUUC-Csa-023938	Chlorocebus sabaeus	36.28	2.00e-94	338.00
IUUC-Cho-024793	Choloepus hoffmanni	33.10	2.00e-37	148.00
IUUC-Cin-025424	Ciona intestinalis	37.14	3.00e-85	308.00
IUUC-Csv-025949	Ciona savignyi	37.25	1.00e-84	306.00
IUUC-Dre-028835	Danio rerio	36.10	2.00e-94	338.00
IUUC-Dno-029080	Dasypus novemcinctus	36.66	3.00e-91	327.00
IUUC-Dor-031092	Dipodomys ordii	33.70	1.00e-84	305.00
IUUC-Ete-033169	Echinops telfairi	31.98	4.00e-71	261.00
IUUC-Eca-033509	Equus caballus	36.65	3.00e-95	340.00
IUUC-Eeu-034669	Erinaceus europaeus	38.46	3.00e-36	145.00
IUUC-Fca-035813	Felis catus	36.03	5.00e-95	340.00
IUUC-Fal-037222	Ficedula albicollis	35.58	1.00e-95	342.00
IUUC-Gmo-038996	Gadus morhua	36.46	4.00e-96	343.00
IUUC-Gga-040181	Gallus gallus	35.91	9.00e-95	339.00
IUUC-Gac-041763	Gasterosteus aculeatus	35.91	3.00e-95	341.00
IUUC-Ggo-044808	Gorilla gorilla	38.01	1.00e-86	312.00
IUUC-Hsa-045801	Homo sapiens	36.28	2.00e-94	338.00
IUUC-Itr-048568	Ictidomys tridecemlineatus	36.65	8.00e-95	339.00
IUUC-Lch-049531	Latimeria chalumnae	36.10	8.00e-95	339.00
IUUC-Loc-052929	Lepisosteus oculatus	36.28	1.00e-95	342.00
IUUC-Laf-053593	Loxodonta africana	36.10	2.00e-93	335.00
IUUC-Mcc-055065	Macaca mulatta	36.28	2.00e-94	338.00
IUUC-Meu-056372	Macropus eugenii	39.41	3.00e-35	142.00
IUUC-Mga-059665	Meleagris gallopavo	36.23	3.00e-80	291.00
IUUC-Mmr-061643	Microcebus murinus	36.46	7.00e-94	336.00
IUUC-Mdo-062624	Monodelphis domestica	36.46	8.00e-96	343.00
IUUC-Mmu-064210	Mus musculus	36.53	7.00e-96	343.00
IUUC-Mpu-066292	Mustela putorius furo	37.83	5.00e-94	337.00
IUUC-Mlu-066952	Myotis lucifugus	36.46	8.00e-95	339.00
IUUC-Nle-069002	Nomascus leucogenys	36.28	2.00e-94	338.00
IUUC-Opr-070405	Ochotona princeps	38.85	2.00e-89	322.00
IUUC-Ont-071487	Oreochromis niloticus	36.10	5.00e-95	340.00
IUUC-Oan-073274	Ornithorhynchus anatinus	36.23	4.00e-83	300.00
IUUC-Ocu-074788	Oryctolagus cuniculus	36.46	3.00e-95	341.00
IUUC-Ola-086339	Oryzias latipes	36.03	4.00e-94	337.00
IUUC-Oga-089037	Otolemur garnettii	36.46	8.00e-94	336.00
IUUC-Oar-089458	Ovis aries	35.68	2.00e-95	342.00
IUUC-Pan-092120	Papio anubis	36.01	3.00e-91	327.00
IUUC-Psi-093157	Pelodiscus sinensis	35.65	1.00e-95	342.00
IUUC-Pfo-096904	Poecilia formosa	36.28	8.00e-96	343.00
IUUC-Pab-098358	Pongo abelii	36.28	2.00e-94	338.00
IUUC-Pva-102674	Pteropus vampyrus	36.46	2.00e-94	338.00
IUUC-Rno-105352	Rattus norvegicus	36.53	2.00e-96	345.00
IUUC-Sar-113483	Sorex araneus	37.96	2.00e-45	175.00
IUUC-Sbi-114403	Sorghum bicolor	32.65	4.00e-03	34.30
IUUC-Ssc-116170	Sus scrofa	36.46	2.00e-94	338.00
IUUC-Tgu-116968	Taeniopygia guttata	35.22	1.00e-93	336.00
IUUC-Tru-118246	Takifugu rubripes	36.10	2.00e-95	342.00
IUUC-Tni-120692	Tetraodon nigroviridis	36.10	4.00e-95	340.00
IUUC-Ttr-128956	Tursiops truncatus	36.65	8.00e-95	339.00
IUUC-Vpa-130291	Vicugna pacos	33.89	5.00e-85	306.00
IUUC-Xtr-132331	Xenopus tropicalis	36.78	7.00e-81	293.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence