iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-107259

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01137086

Gene Name

BCL6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000013935.1	ENSSHAT00000016513.1	ENSSHAP00000016376.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.20e-14	54.6	32	98

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveik.dvqpevfrallkFlYtgklden 68
           +Dv++vv++e+f+ahk vL+a+S  Fy+ f+ +l+ +   + ++++ ++ pe f  ll+F+Yt++l++ 
   Q: 32   TDVVIVVNREQFRAHKTVLMACSGLFYSIFTDQLKCN--LNVINLDpEINPEGFCILLDFMYTSRLNLR 98
           7**********************************76..69*****88*****************9875 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MASPADSCIQ FTRHASDVLL NLNRLRSRDI LTDVVIVVNR EQFRAHKTVL MACSGLFYSI 60
FTDQLKCNLN VINLDPEINP EGFCILLDFM YTSRLNLREG NIMAVMATAM YLQMEHVVDT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNTC TCTCTCCTCT CTCTCTCTCT CTCTCTCTCT CTCTCTCTCT CTCTCTCTCT 60
CTCTCTCTCT CTTTCTCTCT CTCTCTCTCT AAGACTTTCA TGTCTTGGGT CCTATCAATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005794--C:Golgi apparatus
GO:0005654--C:nucleoplasm
GO:0005657--C:replication fork
GO:0031490--F:chromatin DNA binding
GO:0001161--F:intronic transcription regulatory region sequence-specific DNA binding
GO:0046872--F:metal ion binding
GO:0000977--F:RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001227--F:transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0030036--P:actin cytoskeleton organization
GO:0030183--P:B cell differentiation
GO:0000902--P:cell morphogenesis
GO:0006974--P:cellular response to DNA damage stimulus
GO:0048821--P:erythrocyte development
GO:0002467--P:germinal center formation
GO:0043066--P:negative regulation of apoptotic process
GO:0030308--P:negative regulation of cell growth
GO:0008285--P:negative regulation of cell proliferation
GO:0001953--P:negative regulation of cell-matrix adhesion
GO:2000773--P:negative regulation of cellular senescence
GO:0048294--P:negative regulation of isotype switching to IgE isotypes
GO:0032764--P:negative regulation of mast cell cytokine production
GO:0045746--P:negative regulation of Notch signaling pathway
GO:0035024--P:negative regulation of Rho protein signal transduction
GO:0045629--P:negative regulation of T-helper 2 cell differentiation
GO:0043065--P:positive regulation of apoptotic process
GO:0030890--P:positive regulation of B cell proliferation
GO:0051272--P:positive regulation of cellular component movement
GO:0031065--P:positive regulation of histone deacetylation
GO:0045666--P:positive regulation of neuron differentiation
GO:0000060--P:protein import into nucleus, translocation
GO:0043087--P:regulation of GTPase activity
GO:0050727--P:regulation of inflammatory response
GO:0043380--P:regulation of memory T cell differentiation
GO:0007266--P:Rho protein signal transduction
GO:0007283--P:spermatogenesis
GO:0042092--P:type 2 immune response

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001625	Ailuropoda melanoleuca	83.47	0.00e+00	1188.00
IUUC-Apl-003263	Anas platyrhynchos	78.12	0.00e+00	1131.00
IUUC-Ame-010714	Astyanax mexicanus	59.28	0.00e+00	821.00
IUUC-Bta-012576	Bos taurus	83.75	0.00e+00	1173.00
IUUC-Cja-018906	Callithrix jacchus	82.91	0.00e+00	1187.00
IUUC-Cfa-021058	Canis familiaris	82.28	0.00e+00	1160.00
IUUC-Cpo-022328	Cavia porcellus	83.19	0.00e+00	1211.00
IUUC-Csa-023942	Chlorocebus sabaeus	82.91	0.00e+00	1191.00
IUUC-Cho-024599	Choloepus hoffmanni	79.82	0.00e+00	694.00
IUUC-Cin-025470	Ciona intestinalis	73.43	3.00e-60	226.00
IUUC-Csv-025860	Ciona savignyi	79.69	5.00e-60	226.00
IUUC-Dre-027605	Danio rerio	59.20	0.00e+00	825.00
IUUC-Dno-029476	Dasypus novemcinctus	77.96	0.00e+00	1139.00
IUUC-Dor-030724	Dipodomys ordii	81.51	0.00e+00	1187.00
IUUC-Dme-031902	Drosophila melanogaster	41.67	3.00e-14	73.20
IUUC-Ete-032678	Echinops telfairi	82.58	0.00e+00	1152.00
IUUC-Eca-034377	Equus caballus	83.61	0.00e+00	1188.00
IUUC-Eeu-034532	Erinaceus europaeus	75.84	0.00e+00	1078.00
IUUC-Fca-036465	Felis catus	83.61	0.00e+00	1187.00
IUUC-Fal-036977	Ficedula albicollis	78.71	0.00e+00	1155.00
IUUC-Gmo-039515	Gadus morhua	74.25	1.00e-112	399.00
IUUC-Gga-040505	Gallus gallus	79.24	0.00e+00	1144.00
IUUC-Gac-041393	Gasterosteus aculeatus	59.22	0.00e+00	800.00
IUUC-Gma-043945	Glycine max	31.46	2.00e-04	41.20
IUUC-Ggo-044500	Gorilla gorilla	83.19	0.00e+00	1199.00
IUUC-Hsa-046648	Homo sapiens	83.33	0.00e+00	1196.00
IUUC-Itr-048732	Ictidomys tridecemlineatus	79.41	0.00e+00	1123.00
IUUC-Lch-050387	Latimeria chalumnae	58.78	0.00e+00	775.00
IUUC-Loc-052103	Lepisosteus oculatus	61.14	0.00e+00	845.00
IUUC-Laf-053636	Loxodonta africana	82.77	0.00e+00	1199.00
IUUC-Mcc-055290	Macaca mulatta	82.63	0.00e+00	1185.00
IUUC-Meu-055910	Macropus eugenii	85.39	0.00e+00	1233.00
IUUC-Mga-059925	Meleagris gallopavo	78.96	0.00e+00	1136.00
IUUC-Mmr-060855	Microcebus murinus	83.61	0.00e+00	1199.00
IUUC-Mmu-063292	Mus musculus	82.10	0.00e+00	1174.00
IUUC-Mpu-066598	Mustela putorius furo	83.61	0.00e+00	1165.00
IUUC-Mlu-067370	Myotis lucifugus	81.84	0.00e+00	1172.00
IUUC-Nle-069870	Nomascus leucogenys	82.63	0.00e+00	1185.00
IUUC-Opr-070986	Ochotona princeps	81.18	0.00e+00	1173.00
IUUC-Ont-072475	Oreochromis niloticus	60.39	0.00e+00	769.00
IUUC-Oan-073596	Ornithorhynchus anatinus	83.50	0.00e+00	1167.00
IUUC-Ocu-073970	Oryctolagus cuniculus	83.10	0.00e+00	1210.00
IUUC-Ola-087102	Oryzias latipes	59.12	0.00e+00	800.00
IUUC-Oga-088873	Otolemur garnettii	83.59	0.00e+00	1201.00
IUUC-Oar-090083	Ovis aries	78.71	0.00e+00	1082.00
IUUC-Ptr-090628	Pan troglodytes	83.19	0.00e+00	1193.00
IUUC-Pan-092324	Papio anubis	82.89	0.00e+00	1189.00
IUUC-Psi-093695	Pelodiscus sinensis	79.80	0.00e+00	1107.00
IUUC-Pfo-096460	Poecilia formosa	58.08	0.00e+00	790.00
IUUC-Pab-098012	Pongo abelii	83.05	0.00e+00	1192.00
IUUC-Pca-100127	Procavia capensis	81.71	0.00e+00	1092.00
IUUC-Pva-102830	Pteropus vampyrus	82.21	0.00e+00	1159.00
IUUC-Rno-105752	Rattus norvegicus	83.36	0.00e+00	1191.00
IUUC-Sar-113610	Sorex araneus	78.99	0.00e+00	915.00
IUUC-Ssc-115327	Sus scrofa	83.89	0.00e+00	1190.00
IUUC-Tgu-116457	Taeniopygia guttata	79.24	0.00e+00	1163.00
IUUC-Tru-118520	Takifugu rubripes	58.05	0.00e+00	783.00
IUUC-Tni-119969	Tetraodon nigroviridis	58.52	0.00e+00	778.00
IUUC-Tbe-127327	Tupaia belangeri	76.75	0.00e+00	1068.00
IUUC-Ttr-129204	Tursiops truncatus	83.31	0.00e+00	1160.00
IUUC-Xtr-132937	Xenopus tropicalis	67.51	0.00e+00	904.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence