iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gga-040159

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AADN04000148

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000015351.5	ENSGALT00000024772.5	ENSGALP00000024726.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	9.70e-08	32.8	366	405

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC e  kd +++ pCgH+++++Cl +w    ++s ++  CP Cr
   Q: 366  CKICAENDKD-VKIEPCGHLMCTSCLTAW----QESDGQ-GCPFCR 405
           99********.******************....555555.5****8 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MANSQNGRNP RKGRILGFID AIQDAVGPPK QAAADRRTVE KTWKLMDKVV RLCQNPKLQL 60
KNSPPYILDI LPDTYQHLRL ILSKYDDNQK LAQLSENEYF KIYIDSLMKK SKRAIRLFKE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCAACT CCCAGAACGG CCGGAACCCA CGCAAAGGAC GGATCCTGGG CTTCATCGAC 60
GCCATTCAGG ATGCTGTGGG CCCCCCGAAG CAGGCGGCTG CGGACCGGAG GACTGTAGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR015940--UBA
IPR009060--UBA-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51506--CBL_PTB
PS50030--UBA
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3

SMART

SM00184--RING
SM00165--UBA

Gene Ontology

GO:0005829--C:cytosol
GO:0045121--C:membrane raft
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0005509--F:calcium ion binding
GO:0030971--F:receptor tyrosine kinase binding
GO:0017124--F:SH3 domain binding
GO:0004871--F:signal transducer activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007173--P:epidermal growth factor receptor signaling pathway
GO:0007175--P:negative regulation of epidermal growth factor-activated receptor activity
GO:0006508--P:proteolysis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001412	Ailuropoda melanoleuca	82.68	0.00e+00	1409.00
IUUC-Apl-004148	Anas platyrhynchos	90.60	0.00e+00	1596.00
IUUC-Aca-005204	Anolis carolinensis	80.48	0.00e+00	1397.00
IUUC-Ame-011919	Astyanax mexicanus	64.42	0.00e+00	1037.00
IUUC-Bta-013044	Bos taurus	82.88	0.00e+00	1405.00
IUUC-Cel-018674	Caenorhabditis elegans	56.67	2.00e-133	468.00
IUUC-Cja-018813	Callithrix jacchus	75.72	0.00e+00	1301.00
IUUC-Cfa-021054	Canis familiaris	82.47	0.00e+00	1462.00
IUUC-Cpo-022514	Cavia porcellus	78.22	0.00e+00	1400.00
IUUC-Csa-024110	Chlorocebus sabaeus	82.97	0.00e+00	1432.00
IUUC-Cho-024886	Choloepus hoffmanni	67.89	0.00e+00	946.00
IUUC-Dre-027480	Danio rerio	65.38	0.00e+00	1039.00
IUUC-Dno-028923	Dasypus novemcinctus	82.47	0.00e+00	1395.00
IUUC-Dor-031040	Dipodomys ordii	87.72	0.00e+00	794.00
IUUC-Ete-032406	Echinops telfairi	79.87	0.00e+00	1288.00
IUUC-Eca-033849	Equus caballus	82.37	0.00e+00	1429.00
IUUC-Fca-036224	Felis catus	82.59	0.00e+00	1429.00
IUUC-Fal-036860	Ficedula albicollis	99.24	0.00e+00	1045.00
IUUC-Gac-042312	Gasterosteus aculeatus	84.35	0.00e+00	886.00
IUUC-Ggo-045175	Gorilla gorilla	75.96	0.00e+00	1307.00
IUUC-Hsa-046306	Homo sapiens	83.07	0.00e+00	1434.00
IUUC-Lch-049931	Latimeria chalumnae	60.61	0.00e+00	880.00
IUUC-Loc-052524	Lepisosteus oculatus	68.81	0.00e+00	1083.00
IUUC-Laf-053635	Loxodonta africana	79.88	0.00e+00	1361.00
IUUC-Mcc-055536	Macaca mulatta	82.97	0.00e+00	1430.00
IUUC-Meu-056045	Macropus eugenii	71.27	0.00e+00	1149.00
IUUC-Mga-060177	Meleagris gallopavo	99.05	0.00e+00	1190.00
IUUC-Mmr-061088	Microcebus murinus	82.78	0.00e+00	1431.00
IUUC-Mdo-062020	Monodelphis domestica	84.02	0.00e+00	1440.00
IUUC-Mmu-063114	Mus musculus	84.46	0.00e+00	1419.00
IUUC-Mpu-066632	Mustela putorius furo	83.30	0.00e+00	1463.00
IUUC-Mlu-067145	Myotis lucifugus	82.47	0.00e+00	1427.00
IUUC-Ont-072323	Oreochromis niloticus	74.21	0.00e+00	900.00
IUUC-Oan-073165	Ornithorhynchus anatinus	83.13	0.00e+00	1487.00
IUUC-Ocu-074723	Oryctolagus cuniculus	82.57	0.00e+00	1436.00
IUUC-Oga-088021	Otolemur garnettii	82.26	0.00e+00	1419.00
IUUC-Oar-089809	Ovis aries	82.78	0.00e+00	1411.00
IUUC-Ptr-090834	Pan troglodytes	82.97	0.00e+00	1431.00
IUUC-Pan-092225	Papio anubis	83.07	0.00e+00	1435.00
IUUC-Psi-093317	Pelodiscus sinensis	86.46	0.00e+00	1545.00
IUUC-Pma-094249	Petromyzon marinus	78.36	1.00e-127	448.00
IUUC-Pab-097595	Pongo abelii	83.07	0.00e+00	1433.00
IUUC-Pca-100844	Procavia capensis	67.84	0.00e+00	1090.00
IUUC-Pva-103216	Pteropus vampyrus	77.99	0.00e+00	1392.00
IUUC-Rno-105381	Rattus norvegicus	81.64	0.00e+00	1436.00
IUUC-Sha-107574	Sarcophilus harrisii	83.04	0.00e+00	1421.00
IUUC-Sar-113500	Sorex araneus	72.08	0.00e+00	1171.00
IUUC-Ssc-115856	Sus scrofa	80.89	0.00e+00	1204.00
IUUC-Tgu-116866	Taeniopygia guttata	87.77	0.00e+00	1566.00
IUUC-Tru-118579	Takifugu rubripes	86.34	0.00e+00	888.00
IUUC-Tsy-119167	Tarsius syrichta	83.41	0.00e+00	1022.00
IUUC-Tni-120788	Tetraodon nigroviridis	86.04	0.00e+00	899.00
IUUC-Tbe-127830	Tupaia belangeri	89.32	0.00e+00	1102.00
IUUC-Ttr-128631	Tursiops truncatus	82.99	0.00e+00	1434.00
IUUC-Vpa-130713	Vicugna pacos	81.96	0.00e+00	1245.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence