iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cja-018760

Ensembl Protein ID

ENSCJAP00000011007.2

UniProt Accession

F7IN54; F7IN54_CALJA

Genbank Protein ID

JAB07951.1; JAB21425.1; JAB40013.1

Protein Name

Interferon-induced helicase C domain-containing protein 1

Genbank Nucleotide ID

ACFV01061928; GAMS01001711; GAMQ01001838

Gene Name

IFIH1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000005956.2	ENSCJAT00000011611.2	ENSCJAP00000010998.2
ENSCJAG00000005956.2	ENSCJAT00000011621.2	ENSCJAP00000011007.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	9.90e-53	177.6	7	80

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 1    tdeeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktL...vqkegWfrefl 73
           tde +r+l+s++++rv+++++v++vld yl+ fl++e+ke+i+++++t+gn qa+elLL+tL   v+++gW ref+
   Q: 7    TDESFRYLISCFRARVKMYIQVEPVLD-YLT-FLPAEVKEQIQRTVATSGNIQAVELLLSTLekgVWHLGWAREFV 80
           5899***********************.***.*******************************************6 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MSNGYSTDES FRYLISCFRA RVKMYIQVEP VLDYLTFLPA EVKEQIQRTV ATSGNIQAVE 60
LLLSTLEKGV WHLGWAREFV EALRRAGSPL AARYMNPELT DLPSPTSENA HDECLQLLNL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACAGAAACCA AAGTCAGGCA AATTCATAAG AACTGCCCGC CAGAAAGCTG GACTCGAAGC 60
TCCCACCCGA GTGTGCAGAG GGATCAGCAG TGTCTGGGAC CCCAGGCGCG CACCGCAGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0347--Helicase
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR031964--CARD_dom
IPR011029--DEATH-like_dom
IPR006935--Helicase/UvrB_N
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00271--Helicase_C
PF04851--ResIII
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0003677--F:DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0004386--F:helicase activity
GO:0043021--F:ribonucleoprotein complex binding
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0039530--P:MDA-5 signaling pathway
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0016925--P:protein sumoylation

KEGG

cjc:100392317

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001336	Ailuropoda melanoleuca	82.68	0.00e+00	1604.00
IUUC-Apl-003900	Anas platyrhynchos	60.56	0.00e+00	1183.00
IUUC-Aca-005329	Anolis carolinensis	57.38	0.00e+00	999.00
IUUC-Aor-010183	Aspergillus oryzae	37.50	1.30e+00	26.90
IUUC-Ame-011305	Astyanax mexicanus	56.27	0.00e+00	769.00
IUUC-Bta-012361	Bos taurus	81.85	0.00e+00	1551.00
IUUC-Cfa-020321	Canis familiaris	81.62	0.00e+00	1546.00
IUUC-Cpo-022450	Cavia porcellus	78.58	0.00e+00	1561.00
IUUC-Cre-022916	Chlamydomonas reinhardtii	33.06	5.00e-13	70.10
IUUC-Csa-024194	Chlorocebus sabaeus	93.46	0.00e+00	1715.00
IUUC-Cho-024364	Choloepus hoffmanni	74.85	0.00e+00	1031.00
IUUC-Dre-028305	Danio rerio	54.50	0.00e+00	707.00
IUUC-Dno-029831	Dasypus novemcinctus	84.78	0.00e+00	1644.00
IUUC-Dor-030410	Dipodomys ordii	76.15	0.00e+00	1223.00
IUUC-Ete-032950	Echinops telfairi	66.55	0.00e+00	772.00
IUUC-Eca-034279	Equus caballus	85.09	0.00e+00	1618.00
IUUC-Eeu-034678	Erinaceus europaeus	77.49	0.00e+00	1525.00
IUUC-Fca-035618	Felis catus	85.24	0.00e+00	965.00
IUUC-Fal-037106	Ficedula albicollis	67.73	0.00e+00	962.00
IUUC-Fso-038398	Fusarium solani	26.38	6.00e-28	120.00
IUUC-Gmo-038598	Gadus morhua	48.68	0.00e+00	662.00
IUUC-Gga-040467	Gallus gallus	60.37	0.00e+00	1161.00
IUUC-Gac-042316	Gasterosteus aculeatus	47.17	0.00e+00	823.00
IUUC-Ggo-045461	Gorilla gorilla	92.78	0.00e+00	1699.00
IUUC-Hsa-045771	Homo sapiens	92.78	0.00e+00	1697.00
IUUC-Itr-048762	Ictidomys tridecemlineatus	82.73	0.00e+00	1566.00
IUUC-Lch-049913	Latimeria chalumnae	65.04	0.00e+00	907.00
IUUC-Loc-052768	Lepisosteus oculatus	52.95	0.00e+00	975.00
IUUC-Laf-053933	Loxodonta africana	83.27	0.00e+00	1600.00
IUUC-Mcc-054695	Macaca mulatta	93.37	0.00e+00	1714.00
IUUC-Meu-056829	Macropus eugenii	72.08	0.00e+00	1104.00
IUUC-Mga-059205	Meleagris gallopavo	59.94	0.00e+00	1153.00
IUUC-Mvi-060497	Microbotryum violaceum	30.73	1.00e-16	82.80
IUUC-Mmr-060703	Microcebus murinus	87.13	0.00e+00	1618.00
IUUC-Mdo-063079	Monodelphis domestica	69.68	0.00e+00	1408.00
IUUC-Mmu-064066	Mus musculus	78.36	0.00e+00	1608.00
IUUC-Mac-065264	Musa acuminata	47.06	1.90e+00	28.10
IUUC-Mpu-066261	Mustela putorius furo	82.65	0.00e+00	1570.00
IUUC-Mlu-068196	Myotis lucifugus	81.29	0.00e+00	1538.00
IUUC-Nle-069479	Nomascus leucogenys	88.68	0.00e+00	1632.00
IUUC-Opr-070717	Ochotona princeps	76.06	0.00e+00	1165.00
IUUC-Ont-071702	Oreochromis niloticus	47.36	0.00e+00	847.00
IUUC-Oan-073639	Ornithorhynchus anatinus	66.00	0.00e+00	1188.00
IUUC-Ocu-074521	Oryctolagus cuniculus	85.07	0.00e+00	1648.00
IUUC-Ola-086351	Oryzias latipes	46.08	0.00e+00	810.00
IUUC-Oga-088539	Otolemur garnettii	84.00	0.00e+00	1580.00
IUUC-Oar-090186	Ovis aries	81.46	0.00e+00	1528.00
IUUC-Ptr-090575	Pan troglodytes	88.59	0.00e+00	1626.00
IUUC-Pan-092371	Papio anubis	93.07	0.00e+00	1708.00
IUUC-Psi-093072	Pelodiscus sinensis	63.01	0.00e+00	1234.00
IUUC-Pma-094345	Petromyzon marinus	42.64	3.00e-94	338.00
IUUC-Pfo-096401	Poecilia formosa	52.44	0.00e+00	679.00
IUUC-Pab-097623	Pongo abelii	91.12	0.00e+00	1706.00
IUUC-Pca-100993	Procavia capensis	77.11	0.00e+00	1291.00
IUUC-Pva-102227	Pteropus vampyrus	78.65	0.00e+00	1457.00
IUUC-Rno-105198	Rattus norvegicus	78.19	0.00e+00	1599.00
IUUC-Sha-107622	Sarcophilus harrisii	71.07	0.00e+00	1401.00
IUUC-Sar-113625	Sorex araneus	68.37	0.00e+00	717.00
IUUC-Tgu-117486	Taeniopygia guttata	59.73	0.00e+00	1118.00
IUUC-Tru-118445	Takifugu rubripes	44.53	0.00e+00	800.00
IUUC-Tsy-119512	Tarsius syrichta	85.95	0.00e+00	1567.00
IUUC-Tni-120711	Tetraodon nigroviridis	45.28	0.00e+00	840.00
IUUC-Tbe-127644	Tupaia belangeri	74.15	0.00e+00	1381.00
IUUC-Ttr-128989	Tursiops truncatus	78.15	0.00e+00	1541.00
IUUC-Vpa-130587	Vicugna pacos	77.57	0.00e+00	1233.00
IUUC-Xtr-132127	Xenopus tropicalis	52.65	0.00e+00	1000.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence