iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-045461

Ensembl Protein ID

ENSGGOP00000015505.2

UniProt Accession

G3RIJ8; G3RIJ8_GORGO

Protein Name

Uncharacterized protein

Gene Name

IFIH1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000015893.2	ENSGGOT00000015950.2	ENSGGOP00000015505.2
ENSGGOG00000015893.2	ENSGGOT00000033896.1	ENSGGOP00000027557.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	5.30e-57	190.7	7	80

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 1    tdeeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktL...vqkegWfrefl 73
           tde++r+l+s++++rv+++++v++vld yl+ fl++e+ke+i+++++t+gnmqa+elLL+tL   v+++gW+ref+
   Q: 7    TDENFRYLISCFRARVKMYIQVEPVLD-YLT-FLPAEVKEQIQRTVATSGNMQAVELLLSTLekgVWHLGWTREFV 80
           69*************************.***.*******************************************6 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MSNGYSTDEN FRYLISCFRA RVKMYIQVEP VLDYLTFLPA EVKEQIQRTV ATSGNMQAVE 60
LLLSTLEKGV WHLGWTREFV EALRRTGSPL AARYMNPELT DLPSPSFENA HDEYLQLLNL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCCCGCTGC CCACCTGCCC GCCTGCCCAC CTGCCCAGGT GCGAGTGCAG CCCCGCGCGC 60
CGGCCTGAGA GCCCTGTGGA CAACCTCGTC ATTGTCAGGC ACAGACCGGT AGACCCTGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR031964--CARD_dom
IPR011029--DEATH-like_dom
IPR006935--Helicase/UvrB_N
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00271--Helicase_C
PF04851--ResIII
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0003677--F:DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0043021--F:ribonucleoprotein complex binding
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0039530--P:MDA-5 signaling pathway
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0016925--P:protein sumoylation

KEGG

ggo:101142588

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001336	Ailuropoda melanoleuca	84.24	0.00e+00	1625.00
IUUC-Apl-003900	Anas platyrhynchos	61.64	0.00e+00	1198.00
IUUC-Aca-005329	Anolis carolinensis	59.28	0.00e+00	1028.00
IUUC-Ame-011305	Astyanax mexicanus	48.12	0.00e+00	880.00
IUUC-Bta-012361	Bos taurus	83.41	0.00e+00	1575.00
IUUC-Cja-018760	Callithrix jacchus	92.78	0.00e+00	1744.00
IUUC-Cfa-020321	Canis familiaris	82.80	0.00e+00	1563.00
IUUC-Cpo-022450	Cavia porcellus	80.62	0.00e+00	1585.00
IUUC-Cre-022916	Chlamydomonas reinhardtii	33.33	2.00e-12	68.60
IUUC-Csa-024194	Chlorocebus sabaeus	98.15	0.00e+00	1803.00
IUUC-Cho-024364	Choloepus hoffmanni	76.69	0.00e+00	1048.00
IUUC-Dre-028305	Danio rerio	54.58	0.00e+00	714.00
IUUC-Dno-029831	Dasypus novemcinctus	86.93	0.00e+00	1675.00
IUUC-Dor-030410	Dipodomys ordii	77.97	0.00e+00	1256.00
IUUC-Ete-032950	Echinops telfairi	75.23	0.00e+00	648.00
IUUC-Eca-034279	Equus caballus	87.72	0.00e+00	1656.00
IUUC-Eeu-034678	Erinaceus europaeus	80.41	0.00e+00	1571.00
IUUC-Fca-035618	Felis catus	87.87	0.00e+00	983.00
IUUC-Fal-037106	Ficedula albicollis	69.25	0.00e+00	983.00
IUUC-Gmo-038598	Gadus morhua	49.51	0.00e+00	675.00
IUUC-Gga-040467	Gallus gallus	61.11	0.00e+00	1175.00
IUUC-Gac-042316	Gasterosteus aculeatus	47.41	0.00e+00	832.00
IUUC-Hsa-045771	Homo sapiens	99.41	0.00e+00	1830.00
IUUC-Itr-048762	Ictidomys tridecemlineatus	86.34	0.00e+00	1623.00
IUUC-Lch-049913	Latimeria chalumnae	66.26	0.00e+00	931.00
IUUC-Loc-052768	Lepisosteus oculatus	53.68	0.00e+00	985.00
IUUC-Laf-053933	Loxodonta africana	84.63	0.00e+00	1610.00
IUUC-Mcc-054695	Macaca mulatta	98.34	0.00e+00	1811.00
IUUC-Meu-056829	Macropus eugenii	73.90	0.00e+00	1123.00
IUUC-Mga-059205	Meleagris gallopavo	61.82	0.00e+00	1177.00
IUUC-Mmr-060703	Microcebus murinus	88.62	0.00e+00	1639.00
IUUC-Mdo-063079	Monodelphis domestica	71.89	0.00e+00	1439.00
IUUC-Mmu-064066	Mus musculus	79.73	0.00e+00	1623.00
IUUC-Mpu-066261	Mustela putorius furo	83.82	0.00e+00	1582.00
IUUC-Mlu-068196	Myotis lucifugus	82.94	0.00e+00	1558.00
IUUC-Nle-069479	Nomascus leucogenys	93.76	0.00e+00	1728.00
IUUC-Opr-070717	Ochotona princeps	76.17	0.00e+00	1167.00
IUUC-Ont-071702	Oreochromis niloticus	47.31	0.00e+00	848.00
IUUC-Oan-073639	Ornithorhynchus anatinus	66.84	0.00e+00	1208.00
IUUC-Ocu-074521	Oryctolagus cuniculus	86.54	0.00e+00	1671.00
IUUC-Ola-086351	Oryzias latipes	46.47	0.00e+00	823.00
IUUC-Oga-088539	Otolemur garnettii	85.46	0.00e+00	1607.00
IUUC-Oar-090186	Ovis aries	83.41	0.00e+00	1562.00
IUUC-Ptr-090575	Pan troglodytes	94.73	0.00e+00	1746.00
IUUC-Pan-092371	Papio anubis	98.05	0.00e+00	1803.00
IUUC-Psi-093072	Pelodiscus sinensis	64.37	0.00e+00	1256.00
IUUC-Pma-094345	Petromyzon marinus	43.95	7.00e-97	347.00
IUUC-Pfo-096401	Poecilia formosa	51.81	0.00e+00	674.00
IUUC-Pab-097623	Pongo abelii	96.78	0.00e+00	1825.00
IUUC-Pca-100993	Procavia capensis	78.61	0.00e+00	1315.00
IUUC-Pva-102227	Pteropus vampyrus	80.12	0.00e+00	1481.00
IUUC-Rno-105198	Rattus norvegicus	79.65	0.00e+00	1617.00
IUUC-Sha-107622	Sarcophilus harrisii	73.18	0.00e+00	1422.00
IUUC-Sar-113625	Sorex araneus	70.75	0.00e+00	745.00
IUUC-Sre-115121	Sporisorium reilianum	31.11	2.40e-01	32.00
IUUC-Tgu-117486	Taeniopygia guttata	60.52	0.00e+00	1134.00
IUUC-Tru-118445	Takifugu rubripes	45.05	0.00e+00	811.00
IUUC-Tsy-119512	Tarsius syrichta	87.22	0.00e+00	1582.00
IUUC-Tni-120711	Tetraodon nigroviridis	45.37	0.00e+00	847.00
IUUC-Tbe-127644	Tupaia belangeri	75.90	0.00e+00	1399.00
IUUC-Ttr-128989	Tursiops truncatus	80.00	0.00e+00	1571.00
IUUC-Uma-129440	Ustilago maydis	26.67	1.60e+00	29.30
IUUC-Vpa-130587	Vicugna pacos	79.52	0.00e+00	1256.00
IUUC-Xtr-132127	Xenopus tropicalis	54.48	0.00e+00	1034.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence