iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088539

Ensembl Protein ID

ENSOGAP00000011298.2

UniProt Accession

H0X7B9; H0X7B9_OTOGA

Genbank Protein ID

ENSOGAP00000011298

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03118177

Gene Name

IFIH1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000012611.2	ENSOGAT00000012616.2	ENSOGAP00000011298.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	2.30e-39	133.8	8	80

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 2    deeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktL...vqkegWfrefl 73
           d  +r+l+ ++++r++k+++v++vld yl+ fl + +ke+i++ + t+gnm a+elLL+tL    ++ gW++ef+
   Q: 8    DSSFRYLITCFRPRLKKYIQVEPVLD-YLT-FLSADVKEQIQRMVVTSGNMRAVELLLNTLekeEWQPGWTQEFV 80
           6679**********************.***.********************************99********96 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MSNWCSTDSS FRYLITCFRP RLKKYIQVEP VLDYLTFLSA DVKEQIQRMV VTSGNMRAVE 60
LLLNTLEKEE WQPGWTQEFV EALRRAGSPL AARYVNPQLT DLPSPSSENA HDECLQLLTL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGAATT GGTGTTCTAC AGACAGTAGT TTTCGCTATC TCATCACCTG TTTCAGGCCC 60
AGGTTGAAAA AGTACATCCA AGTGGAGCCT GTGCTGGACT ACTTAACCTT TCTGTCTGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR031964--CARD_dom
IPR011029--DEATH-like_dom
IPR006935--Helicase/UvrB_N
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00271--Helicase_C
PF04851--ResIII
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0003677--F:DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0043021--F:ribonucleoprotein complex binding
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0039530--P:MDA-5 signaling pathway
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0016925--P:protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001336	Ailuropoda melanoleuca	80.45	0.00e+00	1571.00
IUUC-Apl-003900	Anas platyrhynchos	59.54	0.00e+00	1165.00
IUUC-Aca-005329	Anolis carolinensis	57.66	0.00e+00	998.00
IUUC-Ame-011305	Astyanax mexicanus	46.12	0.00e+00	830.00
IUUC-Bta-012361	Bos taurus	78.71	0.00e+00	1513.00
IUUC-Cja-018760	Callithrix jacchus	84.00	0.00e+00	1571.00
IUUC-Cfa-020321	Canis familiaris	79.18	0.00e+00	1507.00
IUUC-Cpo-022450	Cavia porcellus	77.29	0.00e+00	1545.00
IUUC-Cre-022916	Chlamydomonas reinhardtii	33.33	2.00e-12	68.60
IUUC-Csa-024194	Chlorocebus sabaeus	86.15	0.00e+00	1588.00
IUUC-Cho-024364	Choloepus hoffmanni	71.50	0.00e+00	1007.00
IUUC-Dre-028305	Danio rerio	47.00	0.00e+00	766.00
IUUC-Dno-029831	Dasypus novemcinctus	80.86	0.00e+00	1555.00
IUUC-Dor-030410	Dipodomys ordii	80.77	0.00e+00	1052.00
IUUC-Ete-032950	Echinops telfairi	72.64	0.00e+00	639.00
IUUC-Eca-034279	Equus caballus	81.46	0.00e+00	1575.00
IUUC-Eeu-034678	Erinaceus europaeus	75.90	0.00e+00	1501.00
IUUC-Fca-035618	Felis catus	82.60	0.00e+00	949.00
IUUC-Fal-037106	Ficedula albicollis	58.23	0.00e+00	1078.00
IUUC-Fso-038398	Fusarium solani	24.87	7.00e-27	116.00
IUUC-Gmo-038598	Gadus morhua	48.61	0.00e+00	675.00
IUUC-Gga-040467	Gallus gallus	59.46	0.00e+00	1160.00
IUUC-Gac-042316	Gasterosteus aculeatus	47.29	0.00e+00	831.00
IUUC-Ggo-045461	Gorilla gorilla	85.46	0.00e+00	1575.00
IUUC-Hsa-045771	Homo sapiens	85.27	0.00e+00	1569.00
IUUC-Itr-048762	Ictidomys tridecemlineatus	80.88	0.00e+00	1555.00
IUUC-Lch-049913	Latimeria chalumnae	64.27	0.00e+00	910.00
IUUC-Loc-052768	Lepisosteus oculatus	52.13	0.00e+00	958.00
IUUC-Laf-053933	Loxodonta africana	80.82	0.00e+00	1544.00
IUUC-Mcc-054695	Macaca mulatta	86.34	0.00e+00	1594.00
IUUC-Meu-056829	Macropus eugenii	71.13	0.00e+00	1088.00
IUUC-Mga-059205	Meleagris gallopavo	59.55	0.00e+00	1150.00
IUUC-Mvi-060497	Microbotryum violaceum	36.92	8.00e-17	83.60
IUUC-Mmr-060703	Microcebus murinus	85.93	0.00e+00	1600.00
IUUC-Mdo-063079	Monodelphis domestica	69.62	0.00e+00	1379.00
IUUC-Mmu-064066	Mus musculus	77.17	0.00e+00	1574.00
IUUC-Mpu-066261	Mustela putorius furo	80.21	0.00e+00	1531.00
IUUC-Mlu-068196	Myotis lucifugus	79.90	0.00e+00	1479.00
IUUC-Nle-069479	Nomascus leucogenys	82.93	0.00e+00	1536.00
IUUC-Opr-070717	Ochotona princeps	72.66	0.00e+00	1122.00
IUUC-Ont-071702	Oreochromis niloticus	46.73	0.00e+00	850.00
IUUC-Oan-073639	Ornithorhynchus anatinus	66.24	0.00e+00	1187.00
IUUC-Ocu-074521	Oryctolagus cuniculus	82.05	0.00e+00	1573.00
IUUC-Ola-086351	Oryzias latipes	44.84	0.00e+00	786.00
IUUC-Oar-090186	Ovis aries	78.91	0.00e+00	1486.00
IUUC-Ptr-090575	Pan troglodytes	82.44	0.00e+00	1528.00
IUUC-Pan-092371	Papio anubis	86.34	0.00e+00	1592.00
IUUC-Psi-093072	Pelodiscus sinensis	62.23	0.00e+00	1230.00
IUUC-Pma-094345	Petromyzon marinus	43.53	6.00e-95	341.00
IUUC-Pfo-096401	Poecilia formosa	51.19	0.00e+00	660.00
IUUC-Pab-097623	Pongo abelii	84.00	0.00e+00	1571.00
IUUC-Pca-100993	Procavia capensis	75.05	0.00e+00	1266.00
IUUC-Pva-102227	Pteropus vampyrus	76.49	0.00e+00	1428.00
IUUC-Pgr-103529	Puccinia graminis	26.03	7.00e-29	123.00
IUUC-Rno-105198	Rattus norvegicus	76.24	0.00e+00	1547.00
IUUC-Sha-107622	Sarcophilus harrisii	70.71	0.00e+00	1377.00
IUUC-Sar-113625	Sorex araneus	66.89	0.00e+00	709.00
IUUC-Tgu-117486	Taeniopygia guttata	59.18	0.00e+00	1108.00
IUUC-Tru-118445	Takifugu rubripes	45.44	0.00e+00	814.00
IUUC-Tsy-119512	Tarsius syrichta	81.56	0.00e+00	1469.00
IUUC-Tni-120711	Tetraodon nigroviridis	45.46	0.00e+00	838.00
IUUC-Tbe-127644	Tupaia belangeri	74.22	0.00e+00	1385.00
IUUC-Ttr-128989	Tursiops truncatus	75.68	0.00e+00	1492.00
IUUC-Vpa-130587	Vicugna pacos	75.51	0.00e+00	1193.00
IUUC-Xtr-132127	Xenopus tropicalis	53.33	0.00e+00	1016.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence