iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-097623

Ensembl Protein ID

ENSPPYP00000014381.2

UniProt Accession

H2P7N6; H2P7N6_PONAB

Genbank Protein ID

ENSPPYP00000014381

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01002265

Gene Name

IFIH1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000012887.2	ENSPPYT00000014967.2	ENSPPYP00000014381.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	5.60e-44	148.6	7	80

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 1    tdeeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktL...vqkegWfrefl 73
           tde+ r+l+s++++r++++++v++vld yl+ fl++e+ke+i+++++t+gnmqa+elLL+tL   v+++gW+ref+
   Q: 7    TDENSRYLISCFRARMKMYIQVEPVLD-YLT-FLPAEVKEQIQRTVATSGNMQAVELLLSTLekgVWHLGWTREFV 80
           689************************.***.*******************************************6 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MSNGYSTDEN SRYLISCFRA RMKMYIQVEP VLDYLTFLPA EVKEQIQRTV ATSGNMQAVE 60
LLLSTLEKGV WHLGWTREFV EALRRTGSPL AARYMNPELT DLPSPSLENA HDECLQLLNL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGAATG GGTATTCCAC AGACGAGAAT TCCCGCTATC TCATCTCGTG CTTCAGGGCC 60
AGGATGAAAA TGTACATCCA GGTGGAGCCT GTGCTGGACT ACCTGACCTT TCTGCCTGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR031964--CARD_dom
IPR011029--DEATH-like_dom
IPR006935--Helicase/UvrB_N
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00271--Helicase_C
PF04851--ResIII
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0003677--F:DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0043021--F:ribonucleoprotein complex binding
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0039530--P:MDA-5 signaling pathway
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0016925--P:protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001336	Ailuropoda melanoleuca	82.88	0.00e+00	1595.00
IUUC-Apl-003900	Anas platyrhynchos	60.86	0.00e+00	1175.00
IUUC-Aca-005329	Anolis carolinensis	58.99	0.00e+00	1001.00
IUUC-Ame-011305	Astyanax mexicanus	47.25	0.00e+00	851.00
IUUC-Bta-012361	Bos taurus	82.63	0.00e+00	1546.00
IUUC-Cja-018760	Callithrix jacchus	91.12	0.00e+00	1706.00
IUUC-Cfa-020321	Canis familiaris	81.62	0.00e+00	1533.00
IUUC-Cpo-022450	Cavia porcellus	79.07	0.00e+00	1546.00
IUUC-Cre-022916	Chlamydomonas reinhardtii	33.33	2.00e-12	68.60
IUUC-Csa-024194	Chlorocebus sabaeus	96.39	0.00e+00	1765.00
IUUC-Cho-024364	Choloepus hoffmanni	75.21	0.00e+00	1018.00
IUUC-Dre-028305	Danio rerio	54.86	0.00e+00	717.00
IUUC-Dno-029831	Dasypus novemcinctus	85.56	0.00e+00	1639.00
IUUC-Dor-030410	Dipodomys ordii	83.84	0.00e+00	1098.00
IUUC-Ete-032950	Echinops telfairi	67.74	0.00e+00	782.00
IUUC-Eca-034279	Equus caballus	86.35	0.00e+00	1623.00
IUUC-Eeu-034678	Erinaceus europaeus	78.85	0.00e+00	1532.00
IUUC-Fca-035618	Felis catus	88.05	0.00e+00	985.00
IUUC-Fal-037106	Ficedula albicollis	58.99	0.00e+00	1071.00
IUUC-Fso-038398	Fusarium solani	25.85	7.00e-28	120.00
IUUC-Gmo-038598	Gadus morhua	49.51	0.00e+00	673.00
IUUC-Gga-040467	Gallus gallus	60.31	0.00e+00	1149.00
IUUC-Gac-042316	Gasterosteus aculeatus	46.82	0.00e+00	812.00
IUUC-Ggo-045461	Gorilla gorilla	96.78	0.00e+00	1771.00
IUUC-Hsa-045771	Homo sapiens	96.98	0.00e+00	1775.00
IUUC-Itr-048762	Ictidomys tridecemlineatus	84.29	0.00e+00	1579.00
IUUC-Lch-049913	Latimeria chalumnae	66.04	0.00e+00	925.00
IUUC-Loc-052768	Lepisosteus oculatus	53.09	0.00e+00	964.00
IUUC-Laf-053933	Loxodonta africana	83.37	0.00e+00	1575.00
IUUC-Mcc-054695	Macaca mulatta	96.59	0.00e+00	1771.00
IUUC-Meu-056829	Macropus eugenii	74.29	0.00e+00	1125.00
IUUC-Mga-059205	Meleagris gallopavo	60.93	0.00e+00	1152.00
IUUC-Mvi-060497	Microbotryum violaceum	34.56	5.00e-17	84.00
IUUC-Mmr-060703	Microcebus murinus	86.93	0.00e+00	1603.00
IUUC-Mdo-063079	Monodelphis domestica	71.11	0.00e+00	1416.00
IUUC-Mmu-064066	Mus musculus	78.75	0.00e+00	1599.00
IUUC-Mpu-066261	Mustela putorius furo	82.55	0.00e+00	1553.00
IUUC-Mlu-068196	Myotis lucifugus	81.87	0.00e+00	1532.00
IUUC-Nle-069479	Nomascus leucogenys	92.00	0.00e+00	1690.00
IUUC-Opr-070717	Ochotona princeps	75.00	0.00e+00	1146.00
IUUC-Ont-071702	Oreochromis niloticus	46.33	0.00e+00	828.00
IUUC-Oan-073639	Ornithorhynchus anatinus	65.89	0.00e+00	1175.00
IUUC-Ocu-074521	Oryctolagus cuniculus	85.27	0.00e+00	1654.00
IUUC-Ola-086351	Oryzias latipes	45.39	0.00e+00	795.00
IUUC-Oga-088539	Otolemur garnettii	84.00	0.00e+00	1572.00
IUUC-Oar-090186	Ovis aries	82.44	0.00e+00	1533.00
IUUC-Ptr-090575	Pan troglodytes	92.20	0.00e+00	1687.00
IUUC-Pan-092371	Papio anubis	96.29	0.00e+00	1766.00
IUUC-Psi-093072	Pelodiscus sinensis	63.28	0.00e+00	1231.00
IUUC-Pma-094345	Petromyzon marinus	43.76	1.00e-96	347.00
IUUC-Pfo-096401	Poecilia formosa	51.81	0.00e+00	671.00
IUUC-Pca-100993	Procavia capensis	77.11	0.00e+00	1280.00
IUUC-Pva-102227	Pteropus vampyrus	78.56	0.00e+00	1449.00
IUUC-Rno-105198	Rattus norvegicus	78.48	0.00e+00	1588.00
IUUC-Sha-107622	Sarcophilus harrisii	72.70	0.00e+00	1402.00
IUUC-Sar-113625	Sorex araneus	68.54	0.00e+00	712.00
IUUC-Tgu-117486	Taeniopygia guttata	59.46	0.00e+00	1109.00
IUUC-Tru-118445	Takifugu rubripes	43.88	0.00e+00	788.00
IUUC-Tsy-119512	Tarsius syrichta	85.95	0.00e+00	1560.00
IUUC-Tni-120711	Tetraodon nigroviridis	44.60	0.00e+00	826.00
IUUC-Tbe-127644	Tupaia belangeri	74.15	0.00e+00	1364.00
IUUC-Ttr-128989	Tursiops truncatus	79.02	0.00e+00	1541.00
IUUC-Vpa-130587	Vicugna pacos	78.62	0.00e+00	1228.00
IUUC-Xtr-132127	Xenopus tropicalis	53.38	0.00e+00	1009.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence