iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093072

Ensembl Protein ID

ENSPSIP00000008310.1

UniProt Accession

K7FJV0; K7FJV0_PELSI

Genbank Protein ID

ENSPSIP00000008310

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01031450

Gene Name

IFIH1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000007364.1	ENSPSIT00000008353.1	ENSPSIP00000008310.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	8.70e-17	61.5	8	79

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 2    deeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktL...vqkegWfref 72
           +ee+ +l+s+++ r+ +++ v++vld +l   l  +eke i a a   g+ qaa +LL +     ++ gW ++f
   Q: 8    EEEFIYLISCFRTRLTQYIRVVPVLD-CLD-TLSVQEKERIRAVARQGGEQQAAGELLGVGergCKEPGWIQQF 79
           69************************.***.9999*******************99998767777777787777 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

KMSAPSREEE FIYLISCFRT RLTQYIRVVP VLDCLDTLSV QEKERIRAVA RQGGEQQAAG 60
ELLGVGERGC KEPGWIQQFV TALQQGGSDM AVCYVNPSLS QLPSPAEEAD HDMCVKMVQL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGATGTCGG CCCCCTCCCG CGAAGAGGAG TTTATTTATC TGATCTCCTG CTTTAGGACC 60
CGGCTCACGC AGTACATACG GGTGGTGCCG GTGCTGGACT GTCTGGACAC GCTGAGCGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR031964--CARD_dom
IPR011029--DEATH-like_dom
IPR006935--Helicase/UvrB_N
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00271--Helicase_C
PF04851--ResIII
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0003677--F:DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0043021--F:ribonucleoprotein complex binding
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0039530--P:MDA-5 signaling pathway
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0016925--P:protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001336	Ailuropoda melanoleuca	62.19	0.00e+00	1195.00
IUUC-Apl-003900	Anas platyrhynchos	73.68	0.00e+00	1497.00
IUUC-Aca-005329	Anolis carolinensis	64.47	0.00e+00	1160.00
IUUC-Ame-011305	Astyanax mexicanus	48.49	0.00e+00	924.00
IUUC-Bta-012361	Bos taurus	62.37	0.00e+00	1168.00
IUUC-Cja-018760	Callithrix jacchus	63.01	0.00e+00	1150.00
IUUC-Cfa-020321	Canis familiaris	62.25	0.00e+00	1166.00
IUUC-Cpo-022450	Cavia porcellus	61.63	0.00e+00	1165.00
IUUC-Cre-022916	Chlamydomonas reinhardtii	30.77	2.00e-11	65.10
IUUC-Csa-024194	Chlorocebus sabaeus	64.56	0.00e+00	1159.00
IUUC-Cho-024364	Choloepus hoffmanni	58.68	0.00e+00	795.00
IUUC-Dre-028305	Danio rerio	56.45	0.00e+00	753.00
IUUC-Dno-029831	Dasypus novemcinctus	63.27	0.00e+00	1188.00
IUUC-Dor-030410	Dipodomys ordii	69.29	0.00e+00	865.00
IUUC-Ete-032950	Echinops telfairi	63.89	2.00e-158	553.00
IUUC-Eca-034279	Equus caballus	63.96	0.00e+00	1201.00
IUUC-Eeu-034678	Erinaceus europaeus	60.02	0.00e+00	1170.00
IUUC-Fca-035618	Felis catus	68.07	0.00e+00	764.00
IUUC-Fal-037106	Ficedula albicollis	73.58	0.00e+00	1404.00
IUUC-Fso-038398	Fusarium solani	28.26	5.00e-34	140.00
IUUC-Gmo-038598	Gadus morhua	52.42	0.00e+00	718.00
IUUC-Gga-040467	Gallus gallus	73.41	0.00e+00	1487.00
IUUC-Gac-042316	Gasterosteus aculeatus	47.35	0.00e+00	858.00
IUUC-Ggo-045461	Gorilla gorilla	64.27	0.00e+00	1148.00
IUUC-Hsa-045771	Homo sapiens	64.17	0.00e+00	1144.00
IUUC-Itr-048762	Ictidomys tridecemlineatus	63.43	0.00e+00	1186.00
IUUC-Lch-049913	Latimeria chalumnae	69.69	0.00e+00	990.00
IUUC-Loc-052768	Lepisosteus oculatus	53.94	0.00e+00	1038.00
IUUC-Laf-053933	Loxodonta africana	63.23	0.00e+00	1159.00
IUUC-Mcc-054695	Macaca mulatta	64.56	0.00e+00	1161.00
IUUC-Meu-056829	Macropus eugenii	64.71	0.00e+00	984.00
IUUC-Mga-059205	Meleagris gallopavo	73.50	0.00e+00	1485.00
IUUC-Mmr-060703	Microcebus murinus	62.96	0.00e+00	1150.00
IUUC-Mdo-063079	Monodelphis domestica	62.90	0.00e+00	1242.00
IUUC-Mmu-064066	Mus musculus	62.27	0.00e+00	1201.00
IUUC-Mpu-066261	Mustela putorius furo	62.44	0.00e+00	1197.00
IUUC-Mlu-068196	Myotis lucifugus	61.58	0.00e+00	1140.00
IUUC-Nle-069479	Nomascus leucogenys	63.30	0.00e+00	1148.00
IUUC-Opr-070717	Ochotona princeps	56.22	0.00e+00	830.00
IUUC-Ont-071702	Oreochromis niloticus	49.65	0.00e+00	926.00
IUUC-Oan-073639	Ornithorhynchus anatinus	62.00	0.00e+00	1091.00
IUUC-Ocu-074521	Oryctolagus cuniculus	62.12	0.00e+00	1183.00
IUUC-Ola-086351	Oryzias latipes	47.06	0.00e+00	829.00
IUUC-Oga-088539	Otolemur garnettii	61.81	0.00e+00	1157.00
IUUC-Oar-090186	Ovis aries	62.61	0.00e+00	1143.00
IUUC-Ptr-090575	Pan troglodytes	62.82	0.00e+00	1137.00
IUUC-Pan-092371	Papio anubis	64.76	0.00e+00	1163.00
IUUC-Pma-094345	Petromyzon marinus	44.15	9.00e-101	360.00
IUUC-Pfo-096401	Poecilia formosa	48.05	0.00e+00	815.00
IUUC-Pab-097623	Pongo abelii	63.28	0.00e+00	1145.00
IUUC-Pca-100993	Procavia capensis	57.77	0.00e+00	953.00
IUUC-Pva-102227	Pteropus vampyrus	59.48	0.00e+00	1083.00
IUUC-Pgr-103529	Puccinia graminis	28.04	1.00e-29	125.00
IUUC-Rno-105198	Rattus norvegicus	60.93	0.00e+00	1174.00
IUUC-Sha-107622	Sarcophilus harrisii	64.57	0.00e+00	1259.00
IUUC-Sar-113625	Sorex araneus	70.21	2.00e-130	459.00
IUUC-Tgu-117486	Taeniopygia guttata	71.37	0.00e+00	1404.00
IUUC-Tru-118445	Takifugu rubripes	45.87	0.00e+00	827.00
IUUC-Tsy-119512	Tarsius syrichta	61.65	0.00e+00	1092.00
IUUC-Tni-120711	Tetraodon nigroviridis	45.68	0.00e+00	848.00
IUUC-Tbe-127644	Tupaia belangeri	56.17	0.00e+00	1021.00
IUUC-Ttr-128989	Tursiops truncatus	58.16	0.00e+00	1117.00
IUUC-Vpa-130587	Vicugna pacos	60.61	0.00e+00	960.00
IUUC-Xtr-132127	Xenopus tropicalis	54.10	0.00e+00	1064.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence