iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011337

Ensembl Protein ID

ENSAMXP00000011187.1

UniProt Accession

W5KUC5; W5KUC5_ASTMX

Genbank Protein ID

ENSAMXP00000011187

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01075215

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000010869.1	ENSAMXT00000011187.1	ENSAMXP00000011187.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	4.50e-34	117.4	4590	4746

Active Site

Position(s)	Description	Evidence
4679	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    Rlkkelkelekdpp....egisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltk.....ifhPnvyen 78
           Rl++e+ +l+++ p    +++++++++e  l+ ++vli+Gp+dtpY++g+F+++++fp+dYP +PP v+++t+     +f+Pn+y++
   Q: 4590 RLAQEAVTLSTSLPlsssSSVFVRCDEE-RLDIMKVLITGPADTPYANGCFEFDVYFPQDYPNSPPLVNLETTgghsvRFNPNLYND 4675
           8999999999998877768899999999.6********************************************************* PP
   S: 79   GkvClsilk.....eeekWsp.alsvesvllsiqsll..aepnpesplneeaa...ellkknreeykkkvre 139
           GkvClsil+     +eekW+p ++s+ +vl+s+qsl+  aep++++p +e+++   + ++++re y+ ++r+
   Q: 4676 GKVCLSILNtwhgrPEEKWNPqTSSFLQVLVSVQSLIlvAEPYFNEPGYERSRgtpSGTQSSRE-YDGNIRQ 4746
           ********7788889******8899***********999***********99866555666655.9998875 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MAAAAAASPG SCSSNSSDWV VLRDGCLRCD EEGLRSLSYH PALNAILAVT SRGSIKVIDG 60
TSGAILQASA LHAKPGGRVR CQYFPAVDKV LFVDDYAVGC RKDLNGILLL DTALQAPVSK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTTGCCCCA GTCCGGATGG TGAATAGCAG CTGCCGCCGC GGTTTCGGGA GGAGAGGAAC 60
AGAAGCGGAG CAGGAGGGAG AGCCGAGCGG GCAGCGCGAC TCCGGACTTC GGAATATTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001370--BIR_rpt
IPR022103--BIRC6
IPR003143--Cyt_cd1_C
IPR008979--Galactose-bd-like
IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50143--BIR_REPEAT_2
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00653--BIR
PF12356--BIRC6
PF00179--UQ_con

SMART

SM00238--BIR

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0006915--P:apoptotic process
GO:0032465--P:regulation of cytokinesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001583	Ailuropoda melanoleuca	77.99	0.00e+00	6749.00
IUUC-Atr-003108	Amborella trichopoda	42.86	4.00e-45	175.00
IUUC-Apl-004144	Anas platyrhynchos	80.73	0.00e+00	4694.00
IUUC-Aca-005257	Anolis carolinensis	77.30	0.00e+00	6700.00
IUUC-Ath-007217	Arabidopsis thaliana	45.20	3.00e-43	169.00
IUUC-Bta-012501	Bos taurus	76.87	0.00e+00	5137.00
IUUC-Bdi-014931	Brachypodium distachyon	47.25	1.00e-46	181.00
IUUC-Bol-015976	Brassica oleracea	45.76	5.00e-45	175.00
IUUC-Bra-017967	Brassica rapa	45.76	2.00e-45	176.00
IUUC-Cel-018661	Caenorhabditis elegans	36.23	8.00e-79	288.00
IUUC-Cja-018746	Callithrix jacchus	78.13	0.00e+00	6735.00
IUUC-Cfa-020170	Canis familiaris	77.84	0.00e+00	6637.00
IUUC-Cpo-022138	Cavia porcellus	78.99	0.00e+00	4580.00
IUUC-Cre-022768	Chlamydomonas reinhardtii	44.13	4.00e-44	171.00
IUUC-Csa-023927	Chlorocebus sabaeus	78.16	0.00e+00	6723.00
IUUC-Cho-024890	Choloepus hoffmanni	72.04	0.00e+00	1425.00
IUUC-Cne-026995	Cryptococcus neoformans	42.62	2.00e-37	151.00
IUUC-Dre-027941	Danio rerio	88.71	0.00e+00	5855.00
IUUC-Dno-028913	Dasypus novemcinctus	76.74	0.00e+00	6598.00
IUUC-Dor-030715	Dipodomys ordii	80.77	0.00e+00	1672.00
IUUC-Dse-031232	Dothistroma septosporum	44.51	3.00e-38	154.00
IUUC-Dme-031592	Drosophila melanogaster	53.15	0.00e+00	675.00
IUUC-Ete-032587	Echinops telfairi	66.71	0.00e+00	1706.00
IUUC-Eca-033819	Equus caballus	78.10	0.00e+00	6721.00
IUUC-Eeu-034863	Erinaceus europaeus	70.96	0.00e+00	1704.00
IUUC-Fca-035505	Felis catus	75.70	0.00e+00	6439.00
IUUC-Fal-037318	Ficedula albicollis	79.11	0.00e+00	6799.00
IUUC-Gmo-039521	Gadus morhua	84.64	0.00e+00	1568.00
IUUC-Ggr-040040	Gaeumannomyces graminis	47.06	3.00e-33	137.00
IUUC-Gga-040728	Gallus gallus	79.12	0.00e+00	6743.00
IUUC-Gac-042251	Gasterosteus aculeatus	87.59	0.00e+00	1664.00
IUUC-Ggo-045562	Gorilla gorilla	77.82	0.00e+00	1254.00
IUUC-Hsa-046339	Homo sapiens	78.21	0.00e+00	6700.00
IUUC-Hvu-047441	Hordeum vulgare	47.25	1.00e-47	184.00
IUUC-Itr-048099	Ictidomys tridecemlineatus	76.51	0.00e+00	2097.00
IUUC-Lch-050164	Latimeria chalumnae	78.30	0.00e+00	6655.00
IUUC-Lpe-051294	Leersia perrieri	36.54	2.00e-46	179.00
IUUC-Loc-052800	Lepisosteus oculatus	83.73	0.00e+00	7198.00
IUUC-Laf-054034	Loxodonta africana	77.82	0.00e+00	6713.00
IUUC-Mcc-055267	Macaca mulatta	78.30	0.00e+00	6734.00
IUUC-Meu-056461	Macropus eugenii	75.74	0.00e+00	945.00
IUUC-Mpo-057396	Magnaporthe poae	48.37	5.00e-34	140.00
IUUC-Mtr-057797	Medicago truncatula	38.36	1.00e-47	184.00
IUUC-Mla-059114	Melampsora laricipopulina	28.44	2.00e-41	164.00
IUUC-Mga-059594	Meleagris gallopavo	77.92	0.00e+00	6353.00
IUUC-Mmr-061179	Microcebus murinus	78.37	0.00e+00	6710.00
IUUC-Mdo-062990	Monodelphis domestica	78.50	0.00e+00	6682.00
IUUC-Mmu-063825	Mus musculus	77.35	0.00e+00	6627.00
IUUC-Mac-064881	Musa acuminata	43.41	2.00e-41	163.00
IUUC-Mpu-065908	Mustela putorius furo	79.47	0.00e+00	4378.00
IUUC-Mlu-067106	Myotis lucifugus	77.24	0.00e+00	6635.00
IUUC-Nle-069347	Nomascus leucogenys	78.27	0.00e+00	6711.00
IUUC-Opr-070799	Ochotona princeps	80.86	0.00e+00	1338.00
IUUC-Ont-072046	Oreochromis niloticus	82.81	0.00e+00	6886.00
IUUC-Oan-073415	Ornithorhynchus anatinus	77.85	0.00e+00	2783.00
IUUC-Ocu-074556	Oryctolagus cuniculus	77.83	0.00e+00	6690.00
IUUC-Oba-075870	Oryza barthii	38.93	2.00e-47	182.00
IUUC-Obr-076823	Oryza brachyantha	48.90	5.00e-46	178.00
IUUC-Ogl-077412	Oryza glaberrima	38.93	2.00e-47	183.00
IUUC-Ogu-077966	Oryza glumaepatula	38.93	2.00e-47	182.00
IUUC-Oin-080009	Oryza indica	39.08	3.00e-47	182.00
IUUC-Olo-080416	Oryza longistaminata	39.86	8.00e-40	159.00
IUUC-Ome-081384	Oryza meridionalis	39.13	3.00e-39	156.00
IUUC-Oni-082326	Oryza nivara	39.69	4.00e-47	182.00
IUUC-Opu-083659	Oryza punctata	38.41	6.00e-46	178.00
IUUC-Oru-085077	Oryza rufipogon	38.93	2.00e-47	182.00
IUUC-Osa-086014	Oryza sativa	38.93	2.00e-47	182.00
IUUC-Ola-087459	Oryzias latipes	83.96	0.00e+00	2858.00
IUUC-Oga-088251	Otolemur garnettii	76.39	0.00e+00	6371.00
IUUC-Oar-090367	Ovis aries	77.86	0.00e+00	5184.00
IUUC-Ptr-091512	Pan troglodytes	78.20	0.00e+00	6709.00
IUUC-Pan-092222	Papio anubis	77.72	0.00e+00	6674.00
IUUC-Pma-094574	Petromyzon marinus	60.46	0.00e+00	2060.00
IUUC-Ppa-095592	Physcomitrella patens	29.64	6.00e-55	209.00
IUUC-Pfo-097086	Poecilia formosa	81.47	0.00e+00	6945.00
IUUC-Pab-098390	Pongo abelii	79.78	0.00e+00	4856.00
IUUC-Pop-099284	Populus trichocarpa	38.62	6.00e-42	165.00
IUUC-Pca-101036	Procavia capensis	71.89	0.00e+00	2312.00
IUUC-Ppe-101722	Prunus persica	45.05	8.00e-44	171.00
IUUC-Pva-103053	Pteropus vampyrus	72.19	0.00e+00	2685.00
IUUC-Pte-104333	Pyrenophora teres	41.79	3.00e-44	174.00
IUUC-Pyt-104498	Pyrenophora triticirepentis	38.96	1.00e-44	174.00
IUUC-Rno-106049	Rattus norvegicus	74.99	0.00e+00	5237.00
IUUC-Sha-107483	Sarcophilus harrisii	75.79	0.00e+00	6270.00
IUUC-Smo-108915	Selaginella moellendorffii	42.22	2.00e-43	169.00
IUUC-Sly-110929	Solanum lycopersicum	39.11	2.00e-46	180.00
IUUC-Stu-112554	Solanum tuberosum	38.71	1.00e-45	178.00
IUUC-Sar-112965	Sorex araneus	74.15	0.00e+00	1022.00
IUUC-Sbi-113880	Sorghum bicolor	46.15	3.00e-44	172.00
IUUC-Ssc-115927	Sus scrofa	79.84	0.00e+00	4727.00
IUUC-Tgu-117132	Taeniopygia guttata	78.80	0.00e+00	6709.00
IUUC-Tru-118115	Takifugu rubripes	78.67	0.00e+00	6683.00
IUUC-Tsy-118899	Tarsius syrichta	75.78	0.00e+00	3917.00
IUUC-Tni-120891	Tetraodon nigroviridis	77.46	0.00e+00	6634.00
IUUC-Tca-121399	Theobroma cacao	44.63	1.00e-42	167.00
IUUC-Tae-125407	Triticum aestivum	47.80	7.00e-48	185.00
IUUC-Tur-126479	Triticum urartu	46.41	7.00e-43	168.00
IUUC-Tme-126930	Tuber melanosporum	42.15	1.00e-47	185.00
IUUC-Tbe-127630	Tupaia belangeri	70.97	0.00e+00	1120.00
IUUC-Ttr-128629	Tursiops truncatus	76.38	0.00e+00	6510.00
IUUC-Vpa-130310	Vicugna pacos	76.85	0.00e+00	6480.00
IUUC-Xtr-131861	Xenopus tropicalis	73.70	0.00e+00	6163.00
IUUC-Xma-133613	Xiphophorus maculatus	81.90	0.00e+00	6919.00
IUUC-Zma-135768	Zea mays	42.86	3.00e-44	174.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence