iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067106

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02028504

Gene Name

BIRC6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000016662.2	ENSMLUT00000016715.2	ENSMLUP00000015232.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	3.10e-34	117.8	4585	4741

Active Site

Position(s)	Description	Evidence
4674	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    Rlkkelkelekdpp....egisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltk.....ifhPnvyen 78
           Rl++e+ +l+++ p    +++++++++e  l+ ++vli+Gp+dtpY++g+F+++++fp+dYP++PP v+++t+     +f+Pn+y++
   Q: 4585 RLAQEAVTLSTSLPlsssSSVFVRCDEE-RLDIMKVLITGPADTPYANGCFEFDVYFPQDYPSSPPLVNLETTgghsvRFNPNLYND 4670
           8999999999998877768899999999.6********************************************************* PP
   S: 79   GkvClsilk.....eeekWsp.alsvesvllsiqsll..aepnpesplneeaa...ellkknreeykkkvre 139
           GkvClsil+     +eekW+p ++s+ +vl+s+qsl+  aep++++p +e+++   + ++++re y+ ++r+
   Q: 4671 GKVCLSILNtwhgrPEEKWNPqTSSFLQVLVSVQSLIlvAEPYFNEPGYERSRgtpSGTQSSRE-YDGNIRQ 4741
           ********7788889******8899***********999***********99866555666655.9998875 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MVTGGGGAPP GTVTEPLPSV IVLSAGRKMA AAAAAASGPG CSSAAGAGAA GASEWLVLRD 60
GCMRCDPDGL HSLSYHPALN AILAVTSRGT IKVIDGTSGA TLQASALSAK PGGQVKCQYI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGACTG GCGGCGGTGG TGCACCTCCC GGGACTGTCA CTGAGCCGCT TCCCAGTGTG 60
ATTGTGCTGA GCGCAGGCCG GAAGATGGCG GCTGCGGCTG CGGCGGCCTC GGGCCCGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR029058--AB_hydrolase
IPR001370--BIR_rpt
IPR022103--BIRC6
IPR008979--Galactose-bd-like
IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD
IPR015943--WD40/YVTN_repeat-like_dom

PROSITE

PS50143--BIR_REPEAT_2
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00653--BIR
PF12356--BIRC6
PF00179--UQ_con

SMART

SM00238--BIR

Gene Ontology

GO:0005768--C:endosome
GO:0016020--C:membrane
GO:0005815--C:microtubule organizing center
GO:0030496--C:midbody
GO:0000922--C:spindle pole
GO:0005802--C:trans-Golgi network
GO:0004869--F:cysteine-type endopeptidase inhibitor activity
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0006915--P:apoptotic process
GO:0060711--P:labyrinthine layer development
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0008284--P:positive regulation of cell proliferation
GO:0032465--P:regulation of cytokinesis
GO:0060712--P:spongiotrophoblast layer development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001583	Ailuropoda melanoleuca	96.71	0.00e+00	8700.00
IUUC-Atr-003108	Amborella trichopoda	42.86	3.00e-45	176.00
IUUC-Apl-004144	Anas platyrhynchos	90.79	0.00e+00	5543.00
IUUC-Aca-005257	Anolis carolinensis	88.23	0.00e+00	7938.00
IUUC-Aly-005551	Arabidopsis lyrata	37.83	8.00e-44	171.00
IUUC-Ath-007217	Arabidopsis thaliana	45.76	8.00e-44	171.00
IUUC-Ame-011337	Astyanax mexicanus	76.95	0.00e+00	6585.00
IUUC-Bta-012501	Bos taurus	96.00	0.00e+00	8529.00
IUUC-Bdi-014931	Brachypodium distachyon	37.50	2.00e-46	179.00
IUUC-Bol-015976	Brassica oleracea	46.33	1.00e-45	177.00
IUUC-Bra-017967	Brassica rapa	46.33	4.00e-46	178.00
IUUC-Cel-018661	Caenorhabditis elegans	36.20	8.00e-79	288.00
IUUC-Cja-018746	Callithrix jacchus	95.91	0.00e+00	8561.00
IUUC-Cfa-020170	Canis familiaris	96.84	0.00e+00	8517.00
IUUC-Cpo-022138	Cavia porcellus	95.16	0.00e+00	5719.00
IUUC-Cre-022768	Chlamydomonas reinhardtii	44.69	1.00e-44	172.00
IUUC-Csa-023927	Chlorocebus sabaeus	96.08	0.00e+00	8554.00
IUUC-Cho-024890	Choloepus hoffmanni	93.45	0.00e+00	1933.00
IUUC-Cne-026995	Cryptococcus neoformans	39.12	2.00e-37	151.00
IUUC-Dre-027941	Danio rerio	81.26	0.00e+00	4721.00
IUUC-Dno-028913	Dasypus novemcinctus	94.50	0.00e+00	8452.00
IUUC-Dor-030715	Dipodomys ordii	93.51	0.00e+00	1927.00
IUUC-Dse-031232	Dothistroma septosporum	44.51	4.00e-38	153.00
IUUC-Dme-031592	Drosophila melanogaster	52.15	0.00e+00	652.00
IUUC-Ete-032587	Echinops telfairi	77.28	0.00e+00	2059.00
IUUC-Eca-033819	Equus caballus	96.65	0.00e+00	8569.00
IUUC-Eeu-034863	Erinaceus europaeus	92.23	0.00e+00	1628.00
IUUC-Fca-035505	Felis catus	94.12	0.00e+00	8324.00
IUUC-Fal-037318	Ficedula albicollis	90.78	0.00e+00	8130.00
IUUC-Gmo-039521	Gadus morhua	80.54	0.00e+00	1662.00
IUUC-Ggr-040040	Gaeumannomyces graminis	47.06	2.00e-33	138.00
IUUC-Gga-040728	Gallus gallus	90.71	0.00e+00	8058.00
IUUC-Gac-042251	Gasterosteus aculeatus	84.03	0.00e+00	1771.00
IUUC-Ggo-045562	Gorilla gorilla	92.79	0.00e+00	1538.00
IUUC-Hsa-046339	Homo sapiens	96.47	0.00e+00	8514.00
IUUC-Hvu-047441	Hordeum vulgare	46.70	4.00e-47	182.00
IUUC-Itr-048099	Ictidomys tridecemlineatus	95.85	0.00e+00	2678.00
IUUC-Lch-050164	Latimeria chalumnae	84.51	0.00e+00	7425.00
IUUC-Lpe-051294	Leersia perrieri	40.23	3.00e-47	182.00
IUUC-Loc-052800	Lepisosteus oculatus	83.71	0.00e+00	7383.00
IUUC-Laf-054034	Loxodonta africana	95.13	0.00e+00	8507.00
IUUC-Mcc-055267	Macaca mulatta	96.03	0.00e+00	8534.00
IUUC-Meu-056461	Macropus eugenii	89.05	0.00e+00	1182.00
IUUC-Mpo-057396	Magnaporthe poae	49.03	2.00e-34	141.00
IUUC-Mtr-057797	Medicago truncatula	39.11	6.00e-47	181.00
IUUC-Mla-059114	Melampsora laricipopulina	27.43	1.00e-41	165.00
IUUC-Mga-059594	Meleagris gallopavo	90.67	0.00e+00	7650.00
IUUC-Mmr-061179	Microcebus murinus	95.97	0.00e+00	8520.00
IUUC-Mdo-062990	Monodelphis domestica	92.24	0.00e+00	8114.00
IUUC-Mmu-063825	Mus musculus	93.83	0.00e+00	8316.00
IUUC-Mac-064881	Musa acuminata	43.41	7.00e-42	164.00
IUUC-Mpu-065908	Mustela putorius furo	95.89	0.00e+00	5477.00
IUUC-Nle-069347	Nomascus leucogenys	96.59	0.00e+00	8573.00
IUUC-Opr-070799	Ochotona princeps	86.18	0.00e+00	2501.00
IUUC-Ont-072046	Oreochromis niloticus	78.39	0.00e+00	6702.00
IUUC-Oan-073415	Ornithorhynchus anatinus	90.91	0.00e+00	3307.00
IUUC-Ocu-074556	Oryctolagus cuniculus	95.56	0.00e+00	8461.00
IUUC-Oba-075602	Oryza barthii	39.26	3.00e-40	159.00
IUUC-Obr-076463	Oryza brachyantha	36.12	4.00e-47	181.00
IUUC-Ogl-077040	Oryza glaberrima	39.26	3.00e-40	159.00
IUUC-Ogu-078917	Oryza glumaepatula	39.26	3.00e-40	159.00
IUUC-Oin-079561	Oryza indica	39.26	3.00e-40	159.00
IUUC-Olo-080416	Oryza longistaminata	40.74	6.00e-41	163.00
IUUC-Ome-081384	Oryza meridionalis	39.26	4.00e-40	159.00
IUUC-Oni-082241	Oryza nivara	39.26	3.00e-40	159.00
IUUC-Opu-083659	Oryza punctata	38.52	1.00e-46	180.00
IUUC-Oru-084622	Oryza rufipogon	39.26	3.00e-40	159.00
IUUC-Osa-085920	Oryza sativa	39.26	3.00e-40	159.00
IUUC-Ola-087459	Oryzias latipes	81.74	0.00e+00	2852.00
IUUC-Oga-088251	Otolemur garnettii	93.86	0.00e+00	8111.00
IUUC-Oar-090367	Ovis aries	95.90	0.00e+00	8536.00
IUUC-Ptr-091512	Pan troglodytes	96.53	0.00e+00	8573.00
IUUC-Pan-092222	Papio anubis	95.42	0.00e+00	8521.00
IUUC-Pma-094574	Petromyzon marinus	60.48	0.00e+00	2936.00
IUUC-Ppa-095592	Physcomitrella patens	29.69	2.00e-55	210.00
IUUC-Pfo-097086	Poecilia formosa	76.82	0.00e+00	6722.00
IUUC-Pab-098390	Pongo abelii	94.76	0.00e+00	8341.00
IUUC-Pop-099782	Populus trichocarpa	43.96	2.00e-41	164.00
IUUC-Pca-101036	Procavia capensis	88.02	0.00e+00	4111.00
IUUC-Ppe-101722	Prunus persica	36.67	4.00e-43	169.00
IUUC-Pva-103053	Pteropus vampyrus	91.62	0.00e+00	3555.00
IUUC-Pte-104333	Pyrenophora teres	41.29	9.00e-44	172.00
IUUC-Pyt-104498	Pyrenophora triticirepentis	39.39	3.00e-44	173.00
IUUC-Rno-106049	Rattus norvegicus	94.14	0.00e+00	6826.00
IUUC-Sha-107483	Sarcophilus harrisii	89.51	0.00e+00	7668.00
IUUC-Smo-108915	Selaginella moellendorffii	42.96	3.00e-44	172.00
IUUC-Sit-110087	Setaria italica	46.63	4.00e-44	172.00
IUUC-Sly-110929	Solanum lycopersicum	38.55	2.00e-46	180.00
IUUC-Stu-112554	Solanum tuberosum	38.55	2.00e-46	181.00
IUUC-Sar-112965	Sorex araneus	86.11	0.00e+00	1806.00
IUUC-Sbi-113880	Sorghum bicolor	34.82	3.00e-45	176.00
IUUC-Ssc-115927	Sus scrofa	96.69	0.00e+00	5941.00
IUUC-Tgu-117132	Taeniopygia guttata	90.72	0.00e+00	8054.00
IUUC-Tru-118115	Takifugu rubripes	75.37	0.00e+00	6585.00
IUUC-Tsy-118899	Tarsius syrichta	93.61	0.00e+00	2969.00
IUUC-Tni-120891	Tetraodon nigroviridis	74.16	0.00e+00	6545.00
IUUC-Tca-121636	Theobroma cacao	44.51	2.00e-42	167.00
IUUC-Tae-125407	Triticum aestivum	47.25	3.00e-47	182.00
IUUC-Tur-126479	Triticum urartu	46.41	2.00e-43	170.00
IUUC-Tme-126930	Tuber melanosporum	42.60	7.00e-48	186.00
IUUC-Tbe-127630	Tupaia belangeri	93.29	0.00e+00	1546.00
IUUC-Ttr-128629	Tursiops truncatus	94.72	0.00e+00	8390.00
IUUC-Vpa-130310	Vicugna pacos	95.65	0.00e+00	8257.00
IUUC-Xtr-131861	Xenopus tropicalis	82.59	0.00e+00	7141.00
IUUC-Xma-133613	Xiphophorus maculatus	79.98	0.00e+00	4526.00
IUUC-Zma-135768	Zea mays	35.67	2.00e-45	178.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence