iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSG00000115827.13	ENST00000375255.7	ENSP00000364404.3
ENSG00000115827.13	ENST00000436317.1	ENSP00000400335.1
ENSG00000115827.13	ENST00000339506.7	ENSP00000342160.3
ENSG00000115827.13	ENST00000431110.1	ENSP00000403992.1
ENSG00000115827.13	ENST00000539783.5	ENSP00000442238.1

Annotation

Cancer Mutation
TCGA	ICGC	COSMIC	CGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	TCGA	ICGC
COSMIC	THPA	HPM
DNA & RNA Element
AREsite	circBase	circRNADb	CircNet
miRTarBase	microRNA	TRANSFAC	TargetScan
RepTar	SomamiR	miRcode	RAID2
Protein-protein Interaction
IID	PINA	HINT	Mentha
InWeb_IM
Disease-associated Information
ClinVar	GWASdb	GWAS Central	OMIM
Post-translational Modifications (PTMs)
CPLM	dbPAF	PhosphositePlus	dbPTM
BioGRID	mUbiSiDa
DNA Methylation
TCGA	ICGC
Protein Expression/Proteomics
THPA	HPM	GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 adaptor/Cullin RING/Other	E3 adaptor/Cullin RING/Other	17588513

Organism

Homo sapiens

Functional Description
(View)

May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

Protein Sequence
(Fasta)

MGPTRKPNVC SRLSRRALGC FSRDAGVVQR TNLGILRALV CQESTKFKNV WTTHSRSPIA 60
YERGRIYFDN YRRCVSSVAS EPRKLYEMPK CSKSEKIEDA LLWECPVGDI LPNSSDYKSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTTCCTGGG AGAAGCCGGG CTGCCTCACG AGGCACTAGG AACTACATTT CCCGGTGAGA 60
GAGCGGCTCC GGCCGGCCGC GCGGTACCGG AGCGTCGCAC TGTCAGCGGC CAGAGAGCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0472--Membrane
KW-0539--Nucleus
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0833--Ubl conjugation pathway

Interpro

IPR031620--DCAF17
IPR015943--WD40/YVTN_repeat-like_dom

Pfam

PF15802--DCAF17

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0016021--C:integral component of membrane
GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0016567--P:protein ubiquitination

KEGG

hsa:80067

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001421	Ailuropoda melanoleuca	92.50	0.00e+00	1011.00
IUUC-Apl-003613	Anas platyrhynchos	74.61	0.00e+00	799.00
IUUC-Aca-004851	Anolis carolinensis	67.18	0.00e+00	750.00
IUUC-Ame-011563	Astyanax mexicanus	52.57	1.00e-155	543.00
IUUC-Bgr-012091	Blumeria graminis	27.91	8.50e-02	32.30
IUUC-Bta-013055	Bos taurus	87.26	0.00e+00	952.00
IUUC-Cja-019331	Callithrix jacchus	95.41	0.00e+00	1041.00
IUUC-Cfa-021200	Canis familiaris	93.27	0.00e+00	992.00
IUUC-Cpo-022074	Cavia porcellus	93.39	0.00e+00	1005.00
IUUC-Csa-023243	Chlorocebus sabaeus	91.60	0.00e+00	990.00
IUUC-Cho-024523	Choloepus hoffmanni	93.26	0.00e+00	672.00
IUUC-Dre-027915	Danio rerio	51.60	1.00e-148	520.00
IUUC-Dno-029577	Dasypus novemcinctus	92.31	0.00e+00	1015.00
IUUC-Dor-030169	Dipodomys ordii	84.39	0.00e+00	900.00
IUUC-Ete-032751	Echinops telfairi	82.15	0.00e+00	879.00
IUUC-Eca-033540	Equus caballus	93.46	0.00e+00	1026.00
IUUC-Eeu-034780	Erinaceus europaeus	72.54	1.00e-98	353.00
IUUC-Fca-035497	Felis catus	91.62	2.00e-96	344.00
IUUC-Fal-036840	Ficedula albicollis	69.34	0.00e+00	741.00
IUUC-Gga-041074	Gallus gallus	74.27	0.00e+00	801.00
IUUC-Gac-042433	Gasterosteus aculeatus	51.46	3.00e-67	248.00
IUUC-Ggo-044943	Gorilla gorilla	98.85	0.00e+00	1071.00
IUUC-Itr-048919	Ictidomys tridecemlineatus	93.26	0.00e+00	1017.00
IUUC-Lch-049836	Latimeria chalumnae	61.90	0.00e+00	687.00
IUUC-Loc-051935	Lepisosteus oculatus	58.30	3.00e-179	621.00
IUUC-Laf-053793	Loxodonta africana	92.90	0.00e+00	1008.00
IUUC-Mcc-055886	Macaca mulatta	97.50	0.00e+00	1060.00
IUUC-Meu-056128	Macropus eugenii	80.81	0.00e+00	873.00
IUUC-Mga-059378	Meleagris gallopavo	74.53	0.00e+00	746.00
IUUC-Mmr-061342	Microcebus murinus	93.45	0.00e+00	974.00
IUUC-Mdo-062809	Monodelphis domestica	85.10	0.00e+00	926.00
IUUC-Mmu-063145	Mus musculus	90.75	0.00e+00	983.00
IUUC-Mpu-066748	Mustela putorius furo	93.08	0.00e+00	1014.00
IUUC-Mlu-067548	Myotis lucifugus	91.57	0.00e+00	989.00
IUUC-Nle-069944	Nomascus leucogenys	98.65	0.00e+00	1071.00
IUUC-Opr-070520	Ochotona princeps	73.91	3.00e-157	548.00
IUUC-Ont-071323	Oreochromis niloticus	49.22	5.00e-147	514.00
IUUC-Oan-073206	Ornithorhynchus anatinus	83.37	0.00e+00	898.00
IUUC-Ocu-074073	Oryctolagus cuniculus	94.26	0.00e+00	995.00
IUUC-Ola-087509	Oryzias latipes	51.35	3.00e-152	531.00
IUUC-Oga-088136	Otolemur garnettii	94.25	0.00e+00	1021.00
IUUC-Oar-089808	Ovis aries	91.71	0.00e+00	1006.00
IUUC-Ptr-090560	Pan troglodytes	99.42	0.00e+00	1080.00
IUUC-Pan-092219	Papio anubis	97.69	0.00e+00	1063.00
IUUC-Psi-093100	Pelodiscus sinensis	76.57	0.00e+00	826.00
IUUC-Pma-094329	Petromyzon marinus	49.06	1.00e-126	447.00
IUUC-Pfo-096391	Poecilia formosa	48.24	3.00e-123	435.00
IUUC-Pab-098156	Pongo abelii	94.23	0.00e+00	1007.00
IUUC-Pca-100142	Procavia capensis	82.12	0.00e+00	881.00
IUUC-Pva-103081	Pteropus vampyrus	82.88	0.00e+00	880.00
IUUC-Rno-105408	Rattus norvegicus	91.14	0.00e+00	988.00
IUUC-Sha-107227	Sarcophilus harrisii	80.00	0.00e+00	876.00
IUUC-Sar-113095	Sorex araneus	87.31	0.00e+00	947.00
IUUC-Ssc-115716	Sus scrofa	93.28	0.00e+00	1019.00
IUUC-Tgu-117398	Taeniopygia guttata	73.91	0.00e+00	787.00
IUUC-Tru-117943	Takifugu rubripes	49.15	6.00e-147	514.00
IUUC-Tsy-118882	Tarsius syrichta	95.95	0.00e+00	1047.00
IUUC-Tni-119868	Tetraodon nigroviridis	47.54	9.00e-139	486.00
IUUC-Tre-122116	Trichoderma reesei	28.33	3.30e-01	31.20
IUUC-Tbe-127470	Tupaia belangeri	81.65	0.00e+00	796.00
IUUC-Ttr-128873	Tursiops truncatus	85.19	0.00e+00	920.00
IUUC-Vpa-130535	Vicugna pacos	85.31	0.00e+00	877.00
IUUC-Xtr-132705	Xenopus tropicalis	64.41	0.00e+00	687.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence