iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033265

Ensembl Protein ID

ENSECAP00000022122.1

UniProt Accession

F6QQA2; F6QQA2_HORSE

Protein Name

Non-specific serine/threonine protein kinase

Gene Name

MARK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000024459.1	ENSECAT00000026510.1	ENSECAP00000022122.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	97.17	0.00e+00	1387.00	IUUC-Hsa-046631

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Equus caballus

Protein Sequence
(Fasta)

HTSVDGYTEP HIQPPKSSSR QNIPRCRNSI TSATDEQPHI GNYRLQKTIG KGNFAKVKLA 60
RHVLTGREVA VKIIDKTQLN PTSLQKLFRE VRIMKILNHP NIVKLFEVIE TEKTLYLVME 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCCGCTCTA AATTTCTGCT CGGACGCCAT TGCCGACGGT GACGGACCGG GGACAACGGA 60
GAATGTGGGT AGCCGGAGCC TCCCGGGCAG CGGCGGGGCG AGACCCTCCT CCGAGCCCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR028375--KA1/Ssp2_C
IPR001772--KA1_dom
IPR011009--Kinase-like_dom
IPR033624--MARK/par1
IPR033627--MARK1
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
IPR015940--UBA

PROSITE

PS50032--KA1
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA

Pfam

PF02149--KA1
PF00069--Pkinase
PF00627--UBA

SMART

SM00220--S_TKc
SM00165--UBA

Gene Ontology

GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0030010--P:establishment of cell polarity
GO:0000226--P:microtubule cytoskeleton organization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001559	Ailuropoda melanoleuca	97.69	0.00e+00	1448.00
IUUC-Ame-011737	Astyanax mexicanus	73.82	0.00e+00	1019.00
IUUC-Bta-013462	Bos taurus	97.69	0.00e+00	1417.00
IUUC-Cja-019358	Callithrix jacchus	96.79	0.00e+00	1476.00
IUUC-Cfa-020498	Canis familiaris	97.95	0.00e+00	1392.00
IUUC-Cpo-022467	Cavia porcellus	94.34	0.00e+00	1417.00
IUUC-Csa-023035	Chlorocebus sabaeus	97.04	0.00e+00	1486.00
IUUC-Dor-031094	Dipodomys ordii	89.46	0.00e+00	1259.00
IUUC-Ete-032429	Echinops telfairi	84.83	0.00e+00	1204.00
IUUC-Fca-035360	Felis catus	91.67	0.00e+00	1336.00
IUUC-Fal-036617	Ficedula albicollis	91.24	0.00e+00	1205.00
IUUC-Gac-041559	Gasterosteus aculeatus	78.10	0.00e+00	1126.00
IUUC-Hsa-046631	Homo sapiens	97.17	0.00e+00	1486.00
IUUC-Laf-054266	Loxodonta africana	95.12	0.00e+00	1404.00
IUUC-Mcc-054650	Macaca mulatta	97.17	0.00e+00	1484.00
IUUC-Mdo-061932	Monodelphis domestica	92.93	0.00e+00	1328.00
IUUC-Mmu-064104	Mus musculus	94.47	0.00e+00	1384.00
IUUC-Mpu-065989	Mustela putorius furo	96.20	0.00e+00	1178.00
IUUC-Mlu-067700	Myotis lucifugus	96.15	0.00e+00	1336.00
IUUC-Nle-069385	Nomascus leucogenys	96.53	0.00e+00	1472.00
IUUC-Ont-071262	Oreochromis niloticus	79.00	0.00e+00	1143.00
IUUC-Oan-073352	Ornithorhynchus anatinus	92.29	0.00e+00	1367.00
IUUC-Ocu-073777	Oryctolagus cuniculus	97.56	0.00e+00	1421.00
IUUC-Oar-089313	Ovis aries	94.10	0.00e+00	1359.00
IUUC-Ptr-091421	Pan troglodytes	96.92	0.00e+00	1480.00
IUUC-Psi-093307	Pelodiscus sinensis	92.16	0.00e+00	1347.00
IUUC-Pma-094666	Petromyzon marinus	68.84	0.00e+00	1013.00
IUUC-Pab-098232	Pongo abelii	97.43	0.00e+00	1489.00
IUUC-Pca-100975	Procavia capensis	83.81	0.00e+00	838.00
IUUC-Pva-102596	Pteropus vampyrus	89.80	0.00e+00	1379.00
IUUC-Rno-105027	Rattus norvegicus	94.34	0.00e+00	1374.00
IUUC-Sha-106668	Sarcophilus harrisii	93.32	0.00e+00	1334.00
IUUC-Ssc-115321	Sus scrofa	70.67	0.00e+00	983.00
IUUC-Tgu-116652	Taeniopygia guttata	91.65	0.00e+00	1384.00
IUUC-Tsy-119138	Tarsius syrichta	83.27	0.00e+00	900.00
IUUC-Tni-120412	Tetraodon nigroviridis	78.03	0.00e+00	1126.00
IUUC-Tbe-127841	Tupaia belangeri	97.54	0.00e+00	1216.00
IUUC-Ttr-128406	Tursiops truncatus	97.43	0.00e+00	1439.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence