iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Annotation

Cancer Mutation
TCGA	ICGC	COSMIC	CGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	TCGA	ICGC
COSMIC	THPA	HPM
DNA & RNA Element
UTRdb	AREsite	circBase	CircNet
miRTarBase	microRNA	TRANSFAC	miRWalk
RepTar	SomamiR	miRcode	RAID2
Protein-protein Interaction
HINT	InWeb_IM
Disease-associated Variation
OMIM
Post-translational Modifications (PTMs)
CPLM	BioGRID	mUbiSiDa
DNA Methylation
TCGA	ICGC	COSMIC
Protein Expression/Proteomics
THPA	HPM	GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	34.78	3.00e-04	31.60	IUUC-Ots-000041

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Homo sapiens

Protein Sequence
(Fasta)

MGRPSSPRAA WGTFSPPQRT QVPDCHSARS KTYGNVLVLD GVIQCTERDE FSYQEMIANL 60
PLCSHPNPRK VLIIGGGDGG VLREVVKHPS VESVVQCEID EDVIQVSKKF LPGMAIGYS 119

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Nucleotide Sequence
(Fasta)

GGCGGAGCTG GTCCCGTTGT GCTGCGGCGC CGCGCGGCCT GCAGTCCCGG GCCCGCGCCC 60
CGCGCCGCCC GCCCGCCCGC CATGGAGCCC GGCCCCGACG GCCCCGCCGC CTCCGGCCCC 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0620--Polyamine biosynthesis
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR030374--PABS
IPR030373--PABS_CS
IPR029063--SAM-dependent_MTases

PROSITE

PS01330--PABS_1
PS51006--PABS_2

Gene Ontology

GO:0016740--F:transferase activity
GO:0006596--P:polyamine biosynthetic process

Orthology

Created Date

25-Jun-2017

Protein Fasta Sequence