iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-045052

UUCD1 version

UUC-GoG-00423

Ensembl Protein ID

ENSGGOP00000010165.2

UniProt Accession

G3R4G2; G3R4G2_GORGO

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000010419.2	ENSGGOT00000010462.2	ENSGGOP00000010165.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/APC_C/CDC20	8.70e-148	491.9	172	478
E3 adaptor/Cullin RING/DCX/DWD	2.00e-28	97.6	307	336

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+++ldape+r+d+ylnL+dWss nvlavaL++svylwsa++gd+ +l ++ +++++++sv+wi+eg++lavGt+++ev+++Dv+++k+
   Q: 172  PDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNSVYLWSASSGDILQLLQMeQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKR 260
           689************************************************899*********************************** PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdassse....Plk 173
           +r++t+hsarvg+LsWn+++lssGsr+g+i+h+dvrv+e++++tl++h+qevCGl+w+ d+++LasGGnDn v+vw ++  e    Pl+
   Q: 261  LRNMTSHSARVGSLSWNSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEggwvPLQ 349
           ********************************************************************************9999***** PP
   S: 174  kfkehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvae 262
           +f++h++avka+aw+Pwq+++La+GGGt+Dr+i++wn+++ga+l+++d++sqvcs+lws+++kel+s+hGfa+n++++wkyp+++kvae
   Q: 350  TFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAE 438
           ***************************************************************************************** PP
   S: 263  lkgheaRvlslalspdgeaivtaagDetlrfwklfdkkka 302
           lkgh++Rvlsl++spdg+++++aa+Detlr+w++f+ ++a
   Q: 439  LKGHTSRVLSLTMSPDGATVASAAADETLRLWRCFELDPA 478
           ***********************************99876 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvW 28
           gH+ +v++l++ +d ++l+sG++D+ + vW
   Q: 307  GHSQEVCGLRWaPDgRHLASGGNDNLVNVW 336
           8***********999*************** PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MAQFAFESDL HSLLQLDAPI PNAPPARWQR KAKEAAGPAP SPMRAANRSH SAGRTPGRTP 60
GKSSSKVQTT PSKPGGDRYI PHRSAAQMEV ASFLLSKENQ PENSQTPTKK EHQKAWALNL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGTAAGCC AGGCGTGTTA AAGCCGGTCG GAACTGCTCC GGAGGGCACG GTGAGAGGTG 60
GTGGGGCTGA GCCGAGGTGG GGCCGTGGCC AGGGGGAGGG GGTGCTAGGC CGGAAGGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033187--CDC20
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

KEGG

ggo:101152075

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000638	Aegilops tauschii	46.77	2.00e-111	395.00
IUUC-Aml-001545	Ailuropoda melanoleuca	97.39	0.00e+00	947.00
IUUC-Atr-003103	Amborella trichopoda	46.92	2.00e-109	389.00
IUUC-Apl-003255	Anas platyrhynchos	80.23	0.00e+00	754.00
IUUC-Aca-004920	Anolis carolinensis	76.23	0.00e+00	778.00
IUUC-Aly-006012	Arabidopsis lyrata	49.02	1.00e-109	389.00
IUUC-Ath-006795	Arabidopsis thaliana	46.71	5.00e-108	384.00
IUUC-Ate-010479	Aspergillus terreus	50.78	3.00e-92	332.00
IUUC-Ame-010850	Astyanax mexicanus	60.70	3.00e-91	328.00
IUUC-Bgr-012059	Blumeria graminis	49.84	1.00e-95	343.00
IUUC-Bta-012625	Bos taurus	97.60	0.00e+00	951.00
IUUC-Bci-013607	Botrytis cinerea	47.95	5.00e-99	355.00
IUUC-Bdi-014344	Brachypodium distachyon	48.67	2.00e-110	392.00
IUUC-Bol-015368	Brassica oleracea	45.88	1.00e-106	381.00
IUUC-Bra-016738	Brassica rapa	46.36	4.00e-106	379.00
IUUC-Cja-019132	Callithrix jacchus	98.80	0.00e+00	964.00
IUUC-Cfa-020780	Canis familiaris	97.60	0.00e+00	947.00
IUUC-Cpo-022223	Cavia porcellus	97.19	0.00e+00	901.00
IUUC-Cre-022701	Chlamydomonas reinhardtii	50.00	2.00e-116	412.00
IUUC-Csa-023666	Chlorocebus sabaeus	99.60	0.00e+00	965.00
IUUC-Cho-024920	Choloepus hoffmanni	96.81	5.00e-161	560.00
IUUC-Cin-025675	Ciona intestinalis	51.39	4.00e-136	478.00
IUUC-Csv-026019	Ciona savignyi	51.13	2.00e-131	462.00
IUUC-Cgl-026465	Colletotrichum gloeosporioides	40.78	3.00e-97	348.00
IUUC-Cme-027234	Cyanidioschyzon merolae	51.91	1.00e-105	377.00
IUUC-Dre-028026	Danio rerio	59.96	0.00e+00	631.00
IUUC-Dno-028865	Dasypus novemcinctus	96.60	0.00e+00	935.00
IUUC-Dor-030958	Dipodomys ordii	96.19	0.00e+00	943.00
IUUC-Dse-031391	Dothistroma septosporum	49.40	4.00e-97	348.00
IUUC-Dme-031905	Drosophila melanogaster	49.44	1.00e-143	503.00
IUUC-Ete-032387	Echinops telfairi	91.98	0.00e+00	903.00
IUUC-Eca-033522	Equus caballus	87.58	0.00e+00	852.00
IUUC-Eeu-035059	Erinaceus europaeus	84.80	0.00e+00	796.00
IUUC-Fca-036346	Felis catus	98.19	0.00e+00	869.00
IUUC-Fal-037558	Ficedula albicollis	80.36	0.00e+00	800.00
IUUC-Fox-037850	Fusarium oxysporum	45.31	2.00e-98	352.00
IUUC-Fso-038375	Fusarium solani	44.56	4.00e-99	355.00
IUUC-Gmo-039284	Gadus morhua	62.30	0.00e+00	632.00
IUUC-Ggr-039864	Gaeumannomyces graminis	48.55	4.00e-99	355.00
IUUC-Gga-040790	Gallus gallus	79.96	0.00e+00	815.00
IUUC-Gac-041431	Gasterosteus aculeatus	61.43	8.00e-180	623.00
IUUC-Gma-043489	Glycine max	46.97	3.00e-107	381.00
IUUC-Hsa-046305	Homo sapiens	100.00	0.00e+00	967.00
IUUC-Hvu-047476	Hordeum vulgare	46.03	7.00e-111	394.00
IUUC-Itr-048461	Ictidomys tridecemlineatus	97.60	0.00e+00	905.00
IUUC-Lch-050174	Latimeria chalumnae	61.39	1.00e-173	602.00
IUUC-Lpe-050954	Leersia perrieri	48.29	1.00e-101	363.00
IUUC-Loc-052638	Lepisosteus oculatus	63.12	0.00e+00	634.00
IUUC-Lma-052998	Leptosphaeria maculans	43.50	7.00e-101	361.00
IUUC-Laf-053742	Loxodonta africana	97.80	0.00e+00	949.00
IUUC-Mcc-054948	Macaca mulatta	99.60	0.00e+00	965.00
IUUC-Meu-056013	Macropus eugenii	86.22	1.00e-142	499.00
IUUC-Mor-057277	Magnaporthe oryzae	45.93	1.00e-96	346.00
IUUC-Mpo-057624	Magnaporthe poae	51.47	4.00e-97	348.00
IUUC-Mtr-057725	Medicago truncatula	46.28	2.00e-100	359.00
IUUC-Mga-060102	Meleagris gallopavo	80.20	0.00e+00	817.00
IUUC-Mmr-061615	Microcebus murinus	98.96	0.00e+00	955.00
IUUC-Mdo-061982	Monodelphis domestica	89.12	0.00e+00	778.00
IUUC-Mmu-063864	Mus musculus	94.79	0.00e+00	934.00
IUUC-Mac-064861	Musa acuminata	47.70	9.00e-111	393.00
IUUC-Mpu-066502	Mustela putorius furo	97.60	0.00e+00	938.00
IUUC-Mlu-067277	Myotis lucifugus	89.62	0.00e+00	884.00
IUUC-Ncr-068951	Neurospora crassa	45.87	1.00e-95	343.00
IUUC-Nle-070149	Nomascus leucogenys	99.60	0.00e+00	961.00
IUUC-Opr-070778	Ochotona princeps	95.54	0.00e+00	689.00
IUUC-Ont-071660	Oreochromis niloticus	61.16	1.00e-178	619.00
IUUC-Oan-073677	Ornithorhynchus anatinus	77.49	0.00e+00	711.00
IUUC-Ocu-073797	Oryctolagus cuniculus	97.38	0.00e+00	947.00
IUUC-Oba-075514	Oryza barthii	48.52	2.00e-101	362.00
IUUC-Obr-076018	Oryza brachyantha	46.83	3.00e-109	388.00
IUUC-Ogl-077254	Oryza glaberrima	48.52	6.00e-102	364.00
IUUC-Ogu-078521	Oryza glumaepatula	48.40	8.00e-109	388.00
IUUC-Oin-080094	Oryza indica	48.52	6.00e-102	364.00
IUUC-Olo-080449	Oryza longistaminata	48.52	5.00e-102	364.00
IUUC-Ome-081186	Oryza meridionalis	48.16	1.00e-108	388.00
IUUC-Oni-082243	Oryza nivara	48.52	6.00e-102	364.00
IUUC-Opu-084007	Oryza punctata	48.29	1.00e-101	363.00
IUUC-Oru-084562	Oryza rufipogon	48.40	2.00e-108	387.00
IUUC-Osa-086094	Oryza sativa	48.29	8.00e-102	363.00
IUUC-Ola-086907	Oryzias latipes	60.83	2.00e-166	578.00
IUUC-Olu-087647	Ostreococcus lucimarinus	49.07	1.00e-119	422.00
IUUC-Oga-088184	Otolemur garnettii	97.40	0.00e+00	944.00
IUUC-Oar-090023	Ovis aries	92.28	0.00e+00	843.00
IUUC-Ptr-090935	Pan troglodytes	98.94	0.00e+00	899.00
IUUC-Pan-091845	Papio anubis	99.60	0.00e+00	965.00
IUUC-Psi-093188	Pelodiscus sinensis	80.93	0.00e+00	844.00
IUUC-Pma-094187	Petromyzon marinus	54.36	7.00e-149	520.00
IUUC-Pno-094809	Phaeosphaeria nodorum	41.39	2.00e-101	363.00
IUUC-Ppa-095457	Physcomitrella patens	47.22	5.00e-111	394.00
IUUC-Pfo-097429	Poecilia formosa	58.57	9.00e-161	559.00
IUUC-Pab-098603	Pongo abelii	99.80	0.00e+00	966.00
IUUC-Pop-099654	Populus trichocarpa	46.39	3.00e-103	369.00
IUUC-Pca-101062	Procavia capensis	96.79	0.00e+00	926.00
IUUC-Ppe-101865	Prunus persica	46.76	3.00e-97	348.00
IUUC-Pva-102925	Pteropus vampyrus	95.99	0.00e+00	969.00
IUUC-Pte-104142	Pyrenophora teres	42.64	5.00e-99	355.00
IUUC-Pyt-104693	Pyrenophora triticirepentis	42.48	6.00e-99	354.00
IUUC-Rno-106005	Rattus norvegicus	94.99	0.00e+00	933.00
IUUC-Sha-107472	Sarcophilus harrisii	89.60	0.00e+00	893.00
IUUC-Sja-107919	Schizosaccharomyces japonicus	42.82	2.00e-94	339.00
IUUC-Spo-108075	Schizosaccharomyces pombe	45.34	4.00e-97	348.00
IUUC-Ssl-108507	Sclerotinia sclerotiorum	49.27	3.00e-98	352.00
IUUC-Smo-108922	Selaginella moellendorffii	49.46	6.00e-124	437.00
IUUC-Sit-110732	Setaria italica	47.69	3.00e-110	392.00
IUUC-Sly-111202	Solanum lycopersicum	44.65	4.00e-106	378.00
IUUC-Stu-112676	Solanum tuberosum	45.32	1.00e-97	350.00
IUUC-Sar-113092	Sorex araneus	90.98	0.00e+00	879.00
IUUC-Sbi-114558	Sorghum bicolor	46.24	3.00e-110	392.00
IUUC-Ssc-115710	Sus scrofa	98.20	0.00e+00	955.00
IUUC-Tgu-117100	Taeniopygia guttata	79.56	0.00e+00	800.00
IUUC-Tru-118184	Takifugu rubripes	57.34	1.00e-139	489.00
IUUC-Tsy-118892	Tarsius syrichta	97.87	3.00e-164	570.00
IUUC-Tni-120474	Tetraodon nigroviridis	59.01	1.00e-168	585.00
IUUC-Tca-120949	Theobroma cacao	46.51	4.00e-107	381.00
IUUC-Tre-122211	Trichoderma reesei	40.94	1.00e-97	350.00
IUUC-Tvi-122531	Trichoderma virens	41.19	4.00e-98	352.00
IUUC-Tae-123017	Triticum aestivum	46.24	2.00e-111	395.00
IUUC-Tur-126193	Triticum urartu	46.24	4.00e-111	395.00
IUUC-Tbe-127384	Tupaia belangeri	98.99	1.00e-177	615.00
IUUC-Ttr-128511	Tursiops truncatus	97.60	0.00e+00	946.00
IUUC-Vda-129993	Verticillium dahliae	41.04	9.00e-99	354.00
IUUC-Vvi-131245	Vitis vinifera	47.17	9.00e-95	340.00
IUUC-Xtr-131993	Xenopus tropicalis	73.68	0.00e+00	759.00
IUUC-Xma-133332	Xiphophorus maculatus	61.74	2.00e-177	615.00
IUUC-Zma-135135	Zea mays	47.64	3.00e-108	385.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence