iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048704

Ensembl Protein ID

ENSSTOP00000022107.1

UniProt Accession

I3NCL0; I3NCL0_ICTTR

Genbank Protein ID

ENSSTOP00000022107

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01029047

Gene Name

USP35

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000019692.1	ENSSTOT00000019681.1	ENSSTOP00000022107.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.00e-82	278.0	442	872

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtCY+NS+LQ+L++ +++r+++l+     l e+    ++++l+++lq lf+ l +s++ a+sp+++l+a +   + fs   qq
   Q: 442  GLINLGNTCYVNSILQALFMASDFRHCVLR-----LTEN----NSQPLMTKLQWLFAFLEHSQRPAISPENFLSASW--TPWFSPGTQQ 519
           9*****************************.....4433....3579***************************998..677******* PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           D++E+l++lld+l+ee      k+ ++ +++ k+++  + +e++++ +++ ++++F+g++ ++i cl+c nvssree f+dlsl++p  
   Q: 520  DCSEYLKYLLDRLHEEE-----KTGTRICQKLKQSSLPSPPEEPPSPSSTSVEKMFGGKIVTRICCLHCLNVSSREEAFTDLSLAFPPP 603
           *****************.....667777777777778888999********************************************99 PP
   S: 180  eetkke................................................................................... 185
           e +  +                                                                                   
   Q: 604  ERCRRRrlgsvmlpaedvgapvpsragprrqrkhcitgdappavldigalgspgaggqreeeekekeadpeekeednlgpgshrdpapa 692
           9887779********************************************************************************** PP
   S: 186  .............slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdl 261
                        s+ d+ + f ++e+l+ en+yyce+c ++q+aek ++l++ P++L+l L Rfsf+ ++++r+ki + v++pl L l
   Q: 693  reptcgpvpegsrSVLDLVNYFLSPERLTAENRYYCESCASLQDAEKVVELSQGPRYLVLTLLRFSFDLRTMRRRKILDDVTIPLLLRL 781
           ************************************************************************************99999 PP
   S: 262  spfctspeekqkekkkYeLiavvvHsG.slssGHYvayvkn................ekgkWllfdDskVtevkeeevleetg....st 329
                +        + Y+L++vvvHsG s++sGHY++y+++                 +++W+lf+D++V+ ++ e+v + t+    +t
   Q: 782  PLAGGQ-------GQAYDLCSVVVHSGvSSESGHYYCYAREgaarpapplgtadrpePENQWYLFNDTRVSFSSFESVSNVTSffpkDT 863
           844444.......89**************************99999999999999888999*******************999****** PP
   S: 330  aYvlfYkrr 338
           aYvlfY++r
   Q: 864  AYVLFYRQR 872
           ******985 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MDKILEAVVT SSYPASVKQG LVRRVLEAAR QPLERDQCLA LLALGARLYV GGADELPRRV 60
GCQLLHVAGR HHPDVFAEFF SARRVLRLLQ GGAGPPGARA LACVQLGLQL LPEGPAAEEV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACAAGA TCCTGGAGGC GGTGGTGACC TCGTCATACC CTGCAAGCGT GAAGCAAGGG 60
CTGGTGCGGC GCGTCCTGGA GGCGGCACGG CAGCCACTGG AGAGGGATCA GTGCCTGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001744	Ailuropoda melanoleuca	88.91	0.00e+00	972.00
IUUC-Apl-004121	Anas platyrhynchos	63.57	0.00e+00	1107.00
IUUC-Aca-005070	Anolis carolinensis	60.86	0.00e+00	774.00
IUUC-Bta-012545	Bos taurus	93.93	0.00e+00	1172.00
IUUC-Cja-019731	Callithrix jacchus	94.03	0.00e+00	1140.00
IUUC-Cfa-020095	Canis familiaris	95.52	0.00e+00	1174.00
IUUC-Cpo-021961	Cavia porcellus	90.42	0.00e+00	1332.00
IUUC-Csa-023167	Chlorocebus sabaeus	93.43	0.00e+00	1129.00
IUUC-Dno-029186	Dasypus novemcinctus	83.42	0.00e+00	829.00
IUUC-Dor-030538	Dipodomys ordii	98.87	0.00e+00	986.00
IUUC-Ete-032512	Echinops telfairi	90.91	1.00e-106	380.00
IUUC-Eca-033279	Equus caballus	97.35	0.00e+00	912.00
IUUC-Eeu-035120	Erinaceus europaeus	71.79	0.00e+00	818.00
IUUC-Fca-035969	Felis catus	94.81	0.00e+00	905.00
IUUC-Fal-037625	Ficedula albicollis	64.23	0.00e+00	1129.00
IUUC-Gga-040767	Gallus gallus	63.54	0.00e+00	1139.00
IUUC-Ggo-045323	Gorilla gorilla	93.09	0.00e+00	909.00
IUUC-Hsa-046124	Homo sapiens	94.16	0.00e+00	1135.00
IUUC-Lch-049513	Latimeria chalumnae	58.19	0.00e+00	983.00
IUUC-Loc-052698	Lepisosteus oculatus	52.16	0.00e+00	876.00
IUUC-Laf-053999	Loxodonta africana	88.84	0.00e+00	1544.00
IUUC-Mcc-055266	Macaca mulatta	92.41	0.00e+00	1112.00
IUUC-Meu-056906	Macropus eugenii	75.04	0.00e+00	972.00
IUUC-Mga-059595	Meleagris gallopavo	63.82	0.00e+00	1124.00
IUUC-Mmr-061720	Microcebus murinus	93.28	0.00e+00	699.00
IUUC-Mdo-062167	Monodelphis domestica	72.31	0.00e+00	1284.00
IUUC-Mmu-063298	Mus musculus	93.08	0.00e+00	1145.00
IUUC-Mpu-066195	Mustela putorius furo	94.47	0.00e+00	1156.00
IUUC-Mlu-067583	Myotis lucifugus	82.81	0.00e+00	1077.00
IUUC-Opr-070454	Ochotona princeps	89.88	3.00e-158	552.00
IUUC-Ocu-074121	Oryctolagus cuniculus	86.38	0.00e+00	948.00
IUUC-Oga-088593	Otolemur garnettii	91.43	0.00e+00	1494.00
IUUC-Oar-090140	Ovis aries	93.32	0.00e+00	1154.00
IUUC-Pan-092168	Papio anubis	93.58	0.00e+00	1131.00
IUUC-Psi-093707	Pelodiscus sinensis	65.17	0.00e+00	1154.00
IUUC-Pab-097614	Pongo abelii	93.58	0.00e+00	1128.00
IUUC-Pca-100683	Procavia capensis	88.96	0.00e+00	1113.00
IUUC-Pva-103146	Pteropus vampyrus	81.53	0.00e+00	1024.00
IUUC-Rno-105061	Rattus norvegicus	93.68	0.00e+00	1154.00
IUUC-Sha-106686	Sarcophilus harrisii	72.98	0.00e+00	954.00
IUUC-Tgu-117024	Taeniopygia guttata	66.04	0.00e+00	1153.00
IUUC-Tsy-119505	Tarsius syrichta	81.30	1.00e-167	582.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence