iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059595

UUCD1 version

UUC-MeG-00854

Ensembl Protein ID

ENSMGAP00000016183.2

UniProt Accession

G1NQS4; G1NQS4_MELGA

Protein Name

Uncharacterized protein

Gene Name

USP35

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000015251.2	ENSMGAT00000017155.2	ENSMGAP00000016183.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.80e-81	273.7	446	889

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtCYmNSv+Q+L++ +++r+ +l+  +e +        +++l+++lq lf+ l +s++ a+sp+++l+a +   + f+  +qq
   Q: 446  GLINLGNTCYMNSVIQSLFMASDFRHSVLN-LTEGI--------SQPLMTKLQWLFAFLEHSQRPAISPESFLSASW--PPWFTPGAQQ 523
           9*****************************.55555........569***************************987..788******* PP
   S: 91   DaqEflaflldq..leeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvp 177
           D++E+l++lld+  l+ee  k  +  ++++    k+++ +++  ++++ nk+li+++F+g++ ++i+cl+c n+ssree f+dlsl++p
   Q: 524  DCSEYLKYLLDRqrLHEEE-KIGKRIYQKL----KESSLMSQATEHHSLNKTLIEKMFGGKMMTKIRCLKCLNISSREEAFTDLSLAFP 607
           **********963377777.3334444444....33445556789******************************************** PP
   S: 178  gkeetkke..............................................................................slq 188
             +    +                                                                              s+ 
   Q: 608  PPDRPVRRpfiephknpsqptgspwvrrkppvpgdpaaqpvpvetlgfrepresahplsnsavsvdttkdphlafaeqtcapkdsrSVP 696
           888776668999***************************************************************************** PP
   S: 189  dcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke... 274
           d+++ f ++e+l+ en+y+ce+c ++q+aek  +l++ P++Lil L Rfsf++++++r+ki ++v++p  L+l   ++s+e+++ +   
   Q: 697  DLINYFLSPERLTAENQYHCEQCASLQDAEKVAQLTEGPHYLILTLLRFSFDSHTMKRRKILDNVSIPVVLKLPILVSSEETED-Vcrh 784
           *************************************************************************87666655443.4699 PP
   S: 275  ............kkkYeLiavvvHsG.slssGHYvayvkn....................ekgk......WllfdDskVtevkeeevle 324
                       +  Y+L++vvvHsG s++sGHY++y ++                    +  +      W+lf+D++V+ ++ e+v +
   Q: 785  gedradlgstfvSAVYDLCSVVVHSGiSSESGHYYCYSREctdtvprapprdgapkpasdK--QldfeipWYLFNDTRVSFSSFESVSN 871
           999*********************************************9999999998551..3455677******************* PP
   S: 325  etg....staYvlfYkrr 338
            t+    +taYvlfY++r
   Q: 872  VTSffpkDTAYVLFYRQR 889
           999************985 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MDKILEAVVM SSYPNNVKQG LVRRVIEASK QPMDSEQCWS MLELCTKLYL VGDTKYKREI 60
GKEVLEVYGH YHPEEFEEFF NVRFLLSLLQ EGYGPLGKRS HYVLDYIQLG LQFVLESPSA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATAAGA TACTGGAAGC TGTGGTGATG TCCTCATACC CCAACAATGT GAAGCAAGGG 60
CTTGTGAGGC GCGTCATTGA GGCATCAAAG CAGCCCATGG ACAGTGAGCA ATGCTGGTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004121	Anas platyrhynchos	90.19	0.00e+00	1644.00
IUUC-Aca-005070	Anolis carolinensis	67.54	0.00e+00	895.00
IUUC-Bta-012545	Bos taurus	70.46	0.00e+00	870.00
IUUC-Cja-019731	Callithrix jacchus	70.79	0.00e+00	850.00
IUUC-Cfa-020095	Canis familiaris	67.31	0.00e+00	867.00
IUUC-Cpo-021961	Cavia porcellus	63.37	0.00e+00	972.00
IUUC-Csa-023167	Chlorocebus sabaeus	61.87	0.00e+00	1016.00
IUUC-Cin-025604	Ciona intestinalis	28.96	4.00e-45	174.00
IUUC-Dor-030538	Dipodomys ordii	71.03	0.00e+00	761.00
IUUC-Eeu-035120	Erinaceus europaeus	53.47	3.00e-175	608.00
IUUC-Fal-037625	Ficedula albicollis	87.78	0.00e+00	1670.00
IUUC-Gga-040767	Gallus gallus	94.27	0.00e+00	1838.00
IUUC-Hsa-046124	Homo sapiens	70.63	0.00e+00	857.00
IUUC-Itr-048704	Ictidomys tridecemlineatus	63.01	0.00e+00	1092.00
IUUC-Lch-049513	Latimeria chalumnae	62.00	0.00e+00	1124.00
IUUC-Loc-052698	Lepisosteus oculatus	58.92	0.00e+00	1063.00
IUUC-Laf-053999	Loxodonta africana	64.05	0.00e+00	1123.00
IUUC-Mcc-055266	Macaca mulatta	69.57	0.00e+00	837.00
IUUC-Meu-056906	Macropus eugenii	74.55	0.00e+00	1005.00
IUUC-Mdo-062167	Monodelphis domestica	70.72	0.00e+00	1305.00
IUUC-Mmu-063298	Mus musculus	71.29	0.00e+00	864.00
IUUC-Mpu-066195	Mustela putorius furo	71.45	0.00e+00	856.00
IUUC-Opr-070454	Ochotona princeps	61.71	2.00e-112	399.00
IUUC-Ocu-074121	Oryctolagus cuniculus	58.42	0.00e+00	956.00
IUUC-Oga-088593	Otolemur garnettii	62.54	0.00e+00	1070.00
IUUC-Oar-090140	Ovis aries	70.30	0.00e+00	860.00
IUUC-Pan-092168	Papio anubis	70.79	0.00e+00	855.00
IUUC-Psi-093707	Pelodiscus sinensis	82.68	0.00e+00	1582.00
IUUC-Pma-094349	Petromyzon marinus	45.71	0.00e+00	803.00
IUUC-Pab-097614	Pongo abelii	70.46	0.00e+00	855.00
IUUC-Pca-100683	Procavia capensis	67.49	0.00e+00	825.00
IUUC-Rno-105061	Rattus norvegicus	70.79	0.00e+00	860.00
IUUC-Sha-106686	Sarcophilus harrisii	73.30	0.00e+00	993.00
IUUC-Tgu-117024	Taeniopygia guttata	86.44	0.00e+00	1639.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence