iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066195

Ensembl Protein ID

ENSMPUP00000007958.1

UniProt Accession

M3Y9F1; M3Y9F1_MUSPF

Genbank Protein ID

ENSMPUP00000007958

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01058259

Gene Name

USP35

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000008016.1	ENSMPUT00000008083.1	ENSMPUP00000007958.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.70e-82	276.2	442	914

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtCY+NS+LQ+L++ +++r+++l+     l e+    ++++l+++lq lf+ l +s++ a+sp+++l+a +   + fs   qq
   Q: 442  GLINLGNTCYVNSILQALFMASDFRHCVLR-----LTEN----NSQPLMTKLQWLFAFLEHSQRPAISPENFLSASW--TPWFSPGTQQ 519
           9*****************************.....4433....3579***************************998..677******* PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           D++E+l++lld+l+ee      k+ ++ +++ k+++  + +e++++ +++ ++++F+g++ ++i+cl+c nvssree f+dlsl++p  
   Q: 520  DCSEYLKYLLDRLHEEE-----KTGTRICQKLKQSSLPSPPEEPPSPSPTSVEKMFGGKIVTRIRCLRCLNVSSREEAFTDLSLAFPPT 603
           *****************.....667777777777778888999********************************************** PP
   S: 180  eetkke................................................................................... 185
           e +  +                                                                                   
   Q: 604  ERCRRRrlgsvmlpaediggrepqassqaqvpgrvgprrqrkhcvtgdaptsvlaveglgrqgpgglsrgeekvereeqaeeaaqever 692
           *998889********************************************************************************** PP
   S: 186  .......................................................slqdcLesftkeeelegenkyycekckkkqeaek 219
                                                                  s+ d+ + f  +e+l+ en+yyce c ++q+aek
   Q: 693  tqeeegeeekekeeeeekaekekeaettkekeedspgpgthrgapastpagegsrSVLDLVNYFLCPERLTAENRYYCEPCASLQDAEK 781
           ***************************************************************************************** PP
   S: 220  klklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvkn...... 301
            ++l++ P++Lil L Rfsf+ ++++r+ki + v++pl L l     +        + Y+L++vvvHsG s++sGHY++y+++      
   Q: 782  AVELSQGPRYLILTLLRFSFDLRTMRRRKILDDVSIPLLLRLPLAGGR-------GQAYDLCSVVVHSGvSSESGHYYCYAREgaarpa 863
           *************************************99999855555.......89**************************999999 PP
   S: 302  ..........ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
                      +++W+lf+D++V+ ++ e+v + t+    +taYvlfY++r
   Q: 864  plpgaadrpePENQWYLFNDTRVSFSSFESVSNVTSffpkDTAYVLFYRQR 914
           99999999888999*******************999************985 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MDKILEAVVT SSYPASVKQG LVRRVLEAAR QPLEREQCLA LLALGTRLYV GGADELPRRV 60
GCQLLHVAGR HHPDVFSEFF SARRVLRLLQ GGAGPPGPRA LACVQLGLQL LPEGPAADEV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGTGGCGTCA TGGACAAGAT CCTGGAGGCG GTGGTGACGT CCTCGTACCC CGCGAGTGTG 60
AAGCAGGGGC TGGTGCGGCG CGTGCTGGAG GCGGCGCGGC AGCCGCTGGA GCGGGAGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001744	Ailuropoda melanoleuca	91.87	0.00e+00	1409.00
IUUC-Apl-004121	Anas platyrhynchos	68.64	0.00e+00	922.00
IUUC-Aca-005070	Anolis carolinensis	66.96	3.00e-172	598.00
IUUC-Bta-012545	Bos taurus	93.12	0.00e+00	1186.00
IUUC-Cja-019731	Callithrix jacchus	93.59	0.00e+00	1190.00
IUUC-Cfa-020095	Canis familiaris	92.48	0.00e+00	1577.00
IUUC-Cpo-021961	Cavia porcellus	91.75	0.00e+00	1201.00
IUUC-Csa-023167	Chlorocebus sabaeus	93.05	0.00e+00	1175.00
IUUC-Dno-029186	Dasypus novemcinctus	83.54	0.00e+00	833.00
IUUC-Dor-030538	Dipodomys ordii	97.74	0.00e+00	1000.00
IUUC-Dme-031871	Drosophila melanogaster	31.93	7.00e-46	179.00
IUUC-Ete-032512	Echinops telfairi	91.70	4.00e-107	382.00
IUUC-Eca-033279	Equus caballus	97.15	0.00e+00	910.00
IUUC-Eeu-035120	Erinaceus europaeus	71.75	0.00e+00	844.00
IUUC-Fca-035969	Felis catus	96.03	0.00e+00	954.00
IUUC-Fal-037625	Ficedula albicollis	68.69	0.00e+00	923.00
IUUC-Gga-040767	Gallus gallus	68.49	0.00e+00	922.00
IUUC-Ggo-045323	Gorilla gorilla	92.72	0.00e+00	932.00
IUUC-Hsa-046124	Homo sapiens	94.01	0.00e+00	1176.00
IUUC-Itr-048704	Ictidomys tridecemlineatus	94.47	0.00e+00	1192.00
IUUC-Lch-049513	Latimeria chalumnae	58.12	0.00e+00	771.00
IUUC-Laf-053999	Loxodonta africana	89.00	0.00e+00	1165.00
IUUC-Mcc-055266	Macaca mulatta	92.27	0.00e+00	1151.00
IUUC-Meu-056906	Macropus eugenii	75.85	0.00e+00	1025.00
IUUC-Mga-059595	Meleagris gallopavo	71.62	0.00e+00	890.00
IUUC-Mmr-061720	Microcebus murinus	92.75	0.00e+00	721.00
IUUC-Mdo-062167	Monodelphis domestica	75.22	0.00e+00	1011.00
IUUC-Mmu-063298	Mus musculus	87.88	0.00e+00	1601.00
IUUC-Mlu-067583	Myotis lucifugus	84.56	0.00e+00	1098.00
IUUC-Opr-070454	Ochotona princeps	89.60	1.00e-163	570.00
IUUC-Ocu-074121	Oryctolagus cuniculus	85.44	0.00e+00	970.00
IUUC-Oga-088593	Otolemur garnettii	94.32	0.00e+00	1175.00
IUUC-Oar-090140	Ovis aries	92.53	0.00e+00	1172.00
IUUC-Pan-092168	Papio anubis	93.20	0.00e+00	1177.00
IUUC-Psi-093707	Pelodiscus sinensis	68.44	0.00e+00	932.00
IUUC-Pab-097614	Pongo abelii	93.29	0.00e+00	1170.00
IUUC-Pca-100683	Procavia capensis	87.48	0.00e+00	1152.00
IUUC-Pva-103146	Pteropus vampyrus	81.44	0.00e+00	1068.00
IUUC-Rno-105061	Rattus norvegicus	87.76	0.00e+00	1583.00
IUUC-Sha-106686	Sarcophilus harrisii	73.78	0.00e+00	1001.00
IUUC-Tgu-117024	Taeniopygia guttata	68.74	0.00e+00	927.00
IUUC-Tsy-119505	Tarsius syrichta	79.85	1.00e-171	596.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence