iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ssc-115257

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

CU633371

Gene Name

UBE2B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000011927.2	ENSSSCT00000013051.2	ENSSSCP00000012708.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	3.80e-54	182.5	8	141

Active Site

Position(s)	Description	Evidence
88	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           Rl++++k+l++dpp g+s  p+++ ++++w+++i+Gpe+tp+e+g+Fkl ief+e+YP kPP+v+fl+k+fhPnvy++G++Cl+il+  
   Q: 8    RLMRDFKRLQEDPPVGVSDAPSEN-NIMQWNAVIFGPEGTPFEDGTFKLVIEFSEEYPNKPPTVRFLSKMFHPNVYADGSICLDILQ-- 93
           9*********************99.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkv 137
           ++Wsp+++v+s+l+siqsll+epnp+sp+n++aa+l+++n++ey+k+v
   Q: 94   NRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYHENKREYEKRV 141
           **********************************************98 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MSTPARRRLM RDFKRLQEDP PVGVSDAPSE NNIMQWNAVI FGPEGTPFED GTFKLVIEFS 60
EEYPNKPPTV RFLSKMFHPN VYADGSICLD ILQNRWSPTY DVSSILTSIQ SLLDEPNPNS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCTTTTCTT TCGGACTGAC CGCGGGGCAG CTGGGGAGCA TGTCGACCCC GGCCCGGAGG 60
AGACTTATGC GAGATTTCAA GCGATTGCAA GAGGACCCAC CTGTGGGTGT CAGTGACGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0033503--C:HULC complex
GO:0000790--C:nuclear chromatin
GO:0005657--C:replication fork
GO:0001741--C:XY body
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0060070--P:canonical Wnt signaling pathway
GO:0051026--P:chiasma assembly
GO:0033522--P:histone H2A ubiquitination
GO:0070076--P:histone lysine demethylation
GO:0001701--P:in utero embryonic development
GO:0006344--P:maintenance of chromatin silencing
GO:0045141--P:meiotic telomere clustering
GO:0043066--P:negative regulation of apoptotic process
GO:0043951--P:negative regulation of cAMP-mediated signaling
GO:0033128--P:negative regulation of histone phosphorylation
GO:0010845--P:positive regulation of reciprocal meiotic recombination
GO:0006301--P:postreplication repair
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0006513--P:protein monoubiquitination
GO:0050821--P:protein stabilization
GO:0042493--P:response to drug
GO:0009411--P:response to UV
GO:0007288--P:sperm axoneme assembly
GO:0070193--P:synaptonemal complex organization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002120	Ailuropoda melanoleuca	98.03	5.00e-86	308.00
IUUC-Apl-004063	Anas platyrhynchos	90.60	2.00e-74	270.00
IUUC-Aca-005001	Anolis carolinensis	97.37	7.00e-86	308.00
IUUC-Bta-012840	Bos taurus	98.03	5.00e-86	308.00
IUUC-Cja-019737	Callithrix jacchus	98.03	5.00e-86	308.00
IUUC-Cfa-020244	Canis familiaris	98.03	5.00e-86	308.00
IUUC-Cpo-022192	Cavia porcellus	98.03	5.00e-86	308.00
IUUC-Csa-023430	Chlorocebus sabaeus	98.03	5.00e-86	308.00
IUUC-Cho-024773	Choloepus hoffmanni	77.63	7.00e-63	232.00
IUUC-Dno-029661	Dasypus novemcinctus	98.03	5.00e-86	308.00
IUUC-Dor-030452	Dipodomys ordii	97.81	2.00e-76	276.00
IUUC-Ete-032595	Echinops telfairi	96.05	1.00e-84	304.00
IUUC-Eca-033377	Equus caballus	98.03	5.00e-86	308.00
IUUC-Fca-036336	Felis catus	98.03	5.00e-86	308.00
IUUC-Gga-040494	Gallus gallus	98.03	5.00e-86	308.00
IUUC-Hsa-046239	Homo sapiens	98.03	5.00e-86	308.00
IUUC-Itr-048960	Ictidomys tridecemlineatus	98.03	5.00e-86	308.00
IUUC-Laf-053380	Loxodonta africana	98.03	5.00e-86	308.00
IUUC-Mcc-054819	Macaca mulatta	98.03	3.00e-86	310.00
IUUC-Mga-059863	Meleagris gallopavo	96.43	3.00e-77	279.00
IUUC-Mmr-060630	Microcebus murinus	98.03	5.00e-86	308.00
IUUC-Mdo-062676	Monodelphis domestica	98.03	5.00e-86	308.00
IUUC-Mmu-063491	Mus musculus	98.03	5.00e-86	308.00
IUUC-Mpu-065803	Mustela putorius furo	98.03	5.00e-86	308.00
IUUC-Mlu-067147	Myotis lucifugus	98.03	5.00e-86	308.00
IUUC-Nle-070105	Nomascus leucogenys	98.03	5.00e-86	308.00
IUUC-Opr-070935	Ochotona princeps	98.03	5.00e-86	308.00
IUUC-Oan-072706	Ornithorhynchus anatinus	92.62	2.00e-78	283.00
IUUC-Ocu-074130	Oryctolagus cuniculus	98.03	5.00e-86	308.00
IUUC-Oga-088836	Otolemur garnettii	98.03	5.00e-86	308.00
IUUC-Oar-090141	Ovis aries	98.03	5.00e-86	308.00
IUUC-Ptr-091453	Pan troglodytes	98.03	5.00e-86	308.00
IUUC-Pan-092511	Papio anubis	98.03	5.00e-86	308.00
IUUC-Psi-093968	Pelodiscus sinensis	97.37	7.00e-86	308.00
IUUC-Pab-098121	Pongo abelii	98.03	5.00e-86	308.00
IUUC-Rno-105772	Rattus norvegicus	98.03	2.00e-86	310.00
IUUC-Sha-107650	Sarcophilus harrisii	96.71	5.00e-84	302.00
IUUC-Sar-113429	Sorex araneus	98.03	5.00e-86	308.00
IUUC-Tgu-116604	Taeniopygia guttata	91.98	9.00e-84	301.00
IUUC-Tsy-119000	Tarsius syrichta	98.03	5.00e-86	308.00
IUUC-Tbe-127921	Tupaia belangeri	96.05	1.00e-81	294.00
IUUC-Ttr-129121	Tursiops truncatus	98.03	5.00e-86	308.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence