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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046645
Ensembl Protein ID ENSP00000346603.2
UniProt Accession Q96K62; ZBT45_HUMAN
Genbank Protein ID BAB55079.1; AAH24738.1
Protein Name Zinc finger and BTB domain-containing protein 45; Zinc finger protein 499
Genbank Nucleotide ID AK027392; BC024738
Gene Name ZBTB45; ZNF499
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000119574.12 ENST00000354590.7 ENSP00000346603.2
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbcircBaseCircNetmiRTarBase
microRNATRANSFACTargetScanRepTar
SomamiRmiRcodeRAID2
Protein-protein Interaction
IIDPINAHINTMentha
InWeb_IM
Post-translational Modifications (PTMs)
dbPAFPhosphositePlus
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB 8.70e-07 30.9 33 93
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/BCR/BTB_Other: BTB
   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd.vqpevfrallkFlYtgkld 66
           +Dv++ + +   +ah++vLaa S++F++ +l + +e +      +   v ++ +r+l++FlY+g+l 
   Q: 33   CDVTVRIREASLRAHRCVLAAGSPFFQDKLLLGHSEIR------VPPvVPAQTVRQLVEFLYSGSLV 93
           8*****************************98877776......66448899************985 PP
   
Organism Homo sapiens
Functional Description
(View)

Functional Description


     Belongs to the krueppel C2H2-type zinc-finger protein family.
 Belongs to the krueppel C2H2-type zinc-finger protein family.
Protein Sequence
(Fasta)
MAAAEAVHHI HLQNFSRSLL ETLNGQRLGG HFCDVTVRIR EASLRAHRCV LAAGSPFFQD 60
KLLLGHSEIR VPPVVPAQTV RQLVEFLYSG SLVVAQGEAL QVLTAASVLR IQTVIDECTQ 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046645|E3,BTB_Other|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GTTGAAAACG TGGTGGGTGG GTGCATTGAG GCTGGCCCCG GGGGGGTGGG CCTCAGCCCC 60
CTGTGCGGTG CCCCTGGGGT CGTGAGGTCT CCGGTCCAGG TGACAACGGC TGGGGGCGGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046645|E3,BTB_Other|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR000210--BTB/POZ_dom
IPR023413--GFP-like
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2
Pfam

PF00651--BTB
SMART

SM00225--BTB
SM00355--ZnF_C2H2
Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0046872--F:metal ion binding
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated
KEGG hsa:84878
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001721 Ailuropoda melanoleuca 100.00 9.00e-64 238.00
IUUC-Aca-004394 Anolis carolinensis 82.73 2.00e-56 213.00
IUUC-Cja-019962 Callithrix jacchus 88.73 7.00e-161 560.00
IUUC-Cfa-020336 Canis familiaris 84.05 0.00e+00 629.00
IUUC-Cpo-021531 Cavia porcellus 71.48 8.00e-154 536.00
IUUC-Csa-023241 Chlorocebus sabaeus 98.63 0.00e+00 704.00
IUUC-Dno-029849 Dasypus novemcinctus 76.85 0.00e+00 631.00
IUUC-Dor-030751 Dipodomys ordii 85.10 0.00e+00 676.00
IUUC-Eca-033307 Equus caballus 79.79 5.00e-71 261.00
IUUC-Fca-036433 Felis catus 85.60 0.00e+00 634.00
IUUC-Gga-040949 Gallus gallus 67.57 2.00e-58 219.00
IUUC-Itr-048916 Ictidomys tridecemlineatus 86.27 0.00e+00 675.00
IUUC-Lch-049715 Latimeria chalumnae 62.75 1.00e-52 201.00
IUUC-Mcc-054851 Macaca mulatta 98.59 0.00e+00 681.00
IUUC-Mmr-061608 Microcebus murinus 90.82 0.00e+00 687.00
IUUC-Mmu-064399 Mus musculus 84.23 0.00e+00 676.00
IUUC-Mpu-066018 Mustela putorius furo 86.35 0.00e+00 634.00
IUUC-Nle-070182 Nomascus leucogenys 99.02 0.00e+00 709.00
IUUC-Ont-071503 Oreochromis niloticus 70.00 4.00e-48 185.00
IUUC-Ocu-073772 Oryctolagus cuniculus 83.33 3.00e-105 375.00
IUUC-Oga-088083 Otolemur garnettii 86.50 0.00e+00 639.00
IUUC-Ptr-090750 Pan troglodytes 99.41 0.00e+00 704.00
IUUC-Pan-092912 Papio anubis 98.63 0.00e+00 707.00
IUUC-Pfo-096169 Poecilia formosa 42.81 1.00e-53 204.00
IUUC-Pab-098105 Pongo abelii 98.59 0.00e+00 668.00
IUUC-Pca-101092 Procavia capensis 79.82 1.00e-115 410.00
IUUC-Pva-102528 Pteropus vampyrus 81.78 3.00e-176 611.00
IUUC-Rno-105409 Rattus norvegicus 83.82 0.00e+00 689.00
IUUC-Sja-107872 Schizosaccharomyces japonicus 37.84 1.20e+00 28.10
Created Date 25-Jun-2017

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