iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000002783.1	ENSAMET00000003050.1	ENSAMEP00000002926.1
ENSAMEG00000002783.1	ENSAMET00000003053.1	ENSAMEP00000002929.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.40e-07	32.0	13	47

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkw.....p 30
           C+iCle+fk  p+++pCgH f+ +Cl + w     p
   Q: 13   CSICLEPFKV-PVTTPCGHNFCSSCLdETWaaqgpP 47
           ********88.***************9999665551 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MAELVPLAEE LSCSICLEPF KVPVTTPCGH NFCSSCLDET WAAQGPPYPH CRAVYDARPQ 60
LRKNTVLCAV VEQFLQAEQA RAAPPPPDGW KLPARTAYSP AGQVACDHCL KEPAVKTCLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCAGGAGCG CCATGGCGGA GCTGGTCCCC CTGGCCGAGG AGCTGTCGTG CTCCATCTGC 60
CTGGAGCCCT TCAAGGTGCC GGTCACCACC CCGTGTGGCC ACAACTTCTG CAGCTCGTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF13445--zf-RING_UBOX

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0016604--C:nuclear body
GO:0003723--F:RNA binding
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0046597--P:negative regulation of viral entry into host cell
GO:1902187--P:negative regulation of viral release from host cell
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0006513--P:protein monoubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043627--P:response to estrogen

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004101	Anas platyrhynchos	50.40	4.00e-174	604.00
IUUC-Aca-005025	Anolis carolinensis	47.74	3.00e-173	601.00
IUUC-Bta-012735	Bos taurus	73.93	0.00e+00	943.00
IUUC-Cja-019996	Callithrix jacchus	69.33	2.00e-174	605.00
IUUC-Cfa-020466	Canis familiaris	78.87	0.00e+00	1024.00
IUUC-Cpo-021737	Cavia porcellus	68.59	0.00e+00	867.00
IUUC-Csa-023217	Chlorocebus sabaeus	76.42	0.00e+00	977.00
IUUC-Cho-024346	Choloepus hoffmanni	50.00	1.00e-70	260.00
IUUC-Dno-030082	Dasypus novemcinctus	72.67	0.00e+00	917.00
IUUC-Dor-030335	Dipodomys ordii	50.69	8.00e-122	431.00
IUUC-Ete-032923	Echinops telfairi	68.43	0.00e+00	785.00
IUUC-Eca-033411	Equus caballus	75.62	0.00e+00	966.00
IUUC-Eeu-034656	Erinaceus europaeus	74.47	2.00e-162	565.00
IUUC-Fca-035371	Felis catus	82.55	0.00e+00	1061.00
IUUC-Fal-037008	Ficedula albicollis	47.83	4.00e-164	571.00
IUUC-Gmo-038668	Gadus morhua	34.72	8.00e-105	374.00
IUUC-Gga-040608	Gallus gallus	47.35	1.00e-163	570.00
IUUC-Gac-041409	Gasterosteus aculeatus	35.24	2.00e-115	409.00
IUUC-Ggo-044518	Gorilla gorilla	76.15	0.00e+00	947.00
IUUC-Hsa-045828	Homo sapiens	76.42	0.00e+00	971.00
IUUC-Itr-049070	Ictidomys tridecemlineatus	62.44	0.00e+00	774.00
IUUC-Lch-050478	Latimeria chalumnae	38.34	5.00e-68	252.00
IUUC-Loc-052864	Lepisosteus oculatus	36.90	6.00e-113	401.00
IUUC-Laf-054325	Loxodonta africana	78.51	1.00e-167	582.00
IUUC-Mcc-054920	Macaca mulatta	76.90	0.00e+00	983.00
IUUC-Meu-056367	Macropus eugenii	71.43	8.00e-74	271.00
IUUC-Mga-059975	Meleagris gallopavo	50.40	8.00e-167	580.00
IUUC-Mmr-060748	Microcebus murinus	75.95	0.00e+00	944.00
IUUC-Mdo-062904	Monodelphis domestica	57.54	0.00e+00	673.00
IUUC-Mmu-063891	Mus musculus	69.97	0.00e+00	906.00
IUUC-Mpu-066473	Mustela putorius furo	84.78	0.00e+00	1096.00
IUUC-Mlu-068185	Myotis lucifugus	73.97	0.00e+00	929.00
IUUC-Nle-070177	Nomascus leucogenys	76.90	0.00e+00	966.00
IUUC-Opr-070558	Ochotona princeps	60.67	2.00e-145	508.00
IUUC-Ont-071368	Oreochromis niloticus	34.50	8.00e-108	384.00
IUUC-Ocu-074461	Oryctolagus cuniculus	67.95	7.00e-153	533.00
IUUC-Ola-086503	Oryzias latipes	27.55	2.00e-57	216.00
IUUC-Oga-088937	Otolemur garnettii	70.38	0.00e+00	884.00
IUUC-Oar-089781	Ovis aries	73.41	0.00e+00	647.00
IUUC-Ptr-090771	Pan troglodytes	76.74	0.00e+00	957.00
IUUC-Pan-092830	Papio anubis	77.22	0.00e+00	986.00
IUUC-Psi-093664	Pelodiscus sinensis	50.55	2.00e-174	605.00
IUUC-Pma-094147	Petromyzon marinus	26.93	3.00e-59	223.00
IUUC-Pfo-096528	Poecilia formosa	35.05	2.00e-114	406.00
IUUC-Pab-097588	Pongo abelii	77.37	0.00e+00	966.00
IUUC-Pca-100890	Procavia capensis	69.48	0.00e+00	853.00
IUUC-Pva-102314	Pteropus vampyrus	76.25	0.00e+00	937.00
IUUC-Pgr-103377	Puccinia graminis	40.91	2.00e-04	40.40
IUUC-Rno-105234	Rattus norvegicus	66.92	0.00e+00	859.00
IUUC-Sce-106362	Saccharomyces cerevisiae	42.86	9.00e-08	51.20
IUUC-Sha-106807	Sarcophilus harrisii	52.37	0.00e+00	637.00
IUUC-Sar-113283	Sorex araneus	58.72	4.00e-134	471.00
IUUC-Ssc-115878	Sus scrofa	81.55	4.00e-108	383.00
IUUC-Tgu-117026	Taeniopygia guttata	47.68	2.00e-131	462.00
IUUC-Tru-117794	Takifugu rubripes	34.05	7.00e-101	361.00
IUUC-Tbe-127580	Tupaia belangeri	71.32	6.00e-150	523.00
IUUC-Ttr-128648	Tursiops truncatus	71.76	0.00e+00	658.00
IUUC-Vpa-130254	Vicugna pacos	85.80	8.00e-93	333.00
IUUC-Xtr-132892	Xenopus tropicalis	41.95	6.00e-70	257.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence