iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	9.70e-10	38.8	254	327

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlp.sGitydrssIekwl.asggktcPvtrqpl.teedlvPnltlrrliqawceen 72
           +p+e+lC I +++M+d vv+p +G +y  ++I+  l +s+++tcP+++q   +++ l+ n++lr+ ++++ +e 
   Q: 254  IPDELLCLICKDIMTDAVVIPcCGNSYCDECIRTALlESDEHTCPTCHQNDvSPDALIANKFLRQAVNNFKNET 327
           8********************************998677777*****9975599999*********99998765 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MSCVHYKFSS KLNYDTVTFD GLHISLCDLK KQIMGREKLK AADSDLQITN AQTKEEYTDD 60
NALIPKNSSV IVRRIPIGGV KSTSKTYVIS RTEPVMGTTK AIDDSSASIS LAQLTKTANL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGAGTACGG GGGGGTTCCG GATTATTGTT CTCACGAACC CCCGCTTGTG GTTGGGGGGT 60
ATTTAATCTG AGGCCTTAGG GTCCTTCGTT GTCTTTTGAG TGTTTTGTGT GTGTACATAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR014891--DWNN_domain
IPR033489--RBBP6
IPR003613--Ubox_domain
IPR025829--Zn_knuckle_CX2CX3GHX4C
IPR001878--Znf_CCHC
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51282--DWNN
PS50158--ZF_CCHC
PS50089--ZF_RING_2

Pfam

PF08783--DWNN
PF04564--U-box
PF13696--zf-CCHC_2

SMART

SM01180--DWNN
SM00184--RING
SM00343--ZnF_C2HC

Gene Ontology

GO:0005634--C:nucleus
GO:0003723--F:RNA binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0006974--P:cellular response to DNA damage stimulus
GO:0048568--P:embryonic organ development
GO:0001701--P:in utero embryonic development
GO:0006397--P:mRNA processing
GO:0035264--P:multicellular organism growth
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0006275--P:regulation of DNA replication
GO:0061053--P:somite development

KEGG

rno:308968

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000195	Aegilops tauschii	29.87	3.00e-26	113.00
IUUC-Aml-001655	Ailuropoda melanoleuca	78.18	0.00e+00	1006.00
IUUC-Atr-002768	Amborella trichopoda	38.69	9.00e-18	85.50
IUUC-Apl-004100	Anas platyrhynchos	64.42	0.00e+00	802.00
IUUC-Aca-004345	Anolis carolinensis	66.90	1.00e-114	407.00
IUUC-Aly-006036	Arabidopsis lyrata	30.54	1.00e-34	141.00
IUUC-Ath-006684	Arabidopsis thaliana	31.13	1.00e-34	141.00
IUUC-Ago-007949	Ashbya gossypii	29.71	7.00e-35	141.00
IUUC-Acl-008118	Aspergillus clavatus	31.01	4.00e-26	113.00
IUUC-Afl-008408	Aspergillus flavus	32.08	6.00e-16	78.60
IUUC-Afu-008777	Aspergillus fumigatus	31.59	3.00e-34	139.00
IUUC-Ani-009426	Aspergillus nidulans	30.83	3.00e-35	143.00
IUUC-Ang-009735	Aspergillus niger	30.08	3.00e-32	133.00
IUUC-Aor-010213	Aspergillus oryzae	31.82	5.00e-34	139.00
IUUC-Ate-010474	Aspergillus terreus	29.71	4.00e-31	129.00
IUUC-Ame-010679	Astyanax mexicanus	82.69	1.00e-164	574.00
IUUC-Bgr-012229	Blumeria graminis	32.34	9.00e-38	151.00
IUUC-Bta-012672	Bos taurus	81.05	0.00e+00	1120.00
IUUC-Bci-013880	Botrytis cinerea	31.41	8.00e-35	142.00
IUUC-Bdi-014250	Brachypodium distachyon	28.27	1.00e-35	145.00
IUUC-Bol-015602	Brassica oleracea	31.28	3.00e-39	157.00
IUUC-Bra-016670	Brassica rapa	31.28	5.00e-39	156.00
IUUC-Cel-018532	Caenorhabditis elegans	36.15	2.00e-54	207.00
IUUC-Cja-018843	Callithrix jacchus	80.41	0.00e+00	1166.00
IUUC-Cfa-021107	Canis familiaris	79.37	0.00e+00	1105.00
IUUC-Cre-022712	Chlamydomonas reinhardtii	27.20	1.00e-12	68.20
IUUC-Csa-023397	Chlorocebus sabaeus	79.87	0.00e+00	1174.00
IUUC-Cho-024327	Choloepus hoffmanni	96.30	0.00e+00	944.00
IUUC-Cin-025439	Ciona intestinalis	47.44	5.00e-48	184.00
IUUC-Csv-026162	Ciona savignyi	54.98	1.00e-55	209.00
IUUC-Cgl-026629	Colletotrichum gloeosporioides	30.40	2.00e-28	120.00
IUUC-Cne-026921	Cryptococcus neoformans	29.08	5.00e-39	155.00
IUUC-Cme-027244	Cyanidioschyzon merolae	45.05	6.00e-18	86.70
IUUC-Dre-028023	Danio rerio	75.77	2.00e-161	563.00
IUUC-Dno-029430	Dasypus novemcinctus	79.28	0.00e+00	1106.00
IUUC-Dor-030406	Dipodomys ordii	80.26	0.00e+00	1118.00
IUUC-Dse-031312	Dothistroma septosporum	30.61	4.00e-38	152.00
IUUC-Dme-032133	Drosophila melanogaster	43.07	2.00e-74	275.00
IUUC-Ete-032466	Echinops telfairi	75.98	0.00e+00	1019.00
IUUC-Eca-034174	Equus caballus	80.63	0.00e+00	890.00
IUUC-Eeu-034677	Erinaceus europaeus	94.54	0.00e+00	858.00
IUUC-Fca-035439	Felis catus	79.04	0.00e+00	1080.00
IUUC-Fal-037230	Ficedula albicollis	74.33	0.00e+00	753.00
IUUC-Fox-037976	Fusarium oxysporum	30.32	6.00e-35	142.00
IUUC-Fso-038202	Fusarium solani	29.56	4.00e-34	139.00
IUUC-Gmo-038618	Gadus morhua	67.15	2.00e-74	272.00
IUUC-Ggr-040035	Gaeumannomyces graminis	27.88	3.00e-31	130.00
IUUC-Gga-040908	Gallus gallus	74.74	0.00e+00	732.00
IUUC-Gac-041718	Gasterosteus aculeatus	71.17	2.00e-86	311.00
IUUC-Gma-044229	Glycine max	31.98	2.00e-40	160.00
IUUC-Ggo-044567	Gorilla gorilla	80.20	0.00e+00	1130.00
IUUC-Hsa-046849	Homo sapiens	80.52	0.00e+00	1134.00
IUUC-Hvu-047050	Hordeum vulgare	25.77	4.00e-23	103.00
IUUC-Itr-048832	Ictidomys tridecemlineatus	81.14	0.00e+00	1072.00
IUUC-Kpa-049323	Komagataella pastoris	30.91	2.00e-34	140.00
IUUC-Lch-050524	Latimeria chalumnae	68.98	0.00e+00	730.00
IUUC-Lpe-050947	Leersia perrieri	28.72	9.00e-30	125.00
IUUC-Loc-052709	Lepisosteus oculatus	83.07	4.00e-167	583.00
IUUC-Lma-053186	Leptosphaeria maculans	33.63	1.00e-35	144.00
IUUC-Laf-054472	Loxodonta africana	78.48	0.00e+00	1089.00
IUUC-Mcc-055743	Macaca mulatta	79.76	0.00e+00	1177.00
IUUC-Meu-056399	Macropus eugenii	78.68	0.00e+00	764.00
IUUC-Mor-057073	Magnaporthe oryzae	30.06	5.00e-32	132.00
IUUC-Mpo-057378	Magnaporthe poae	27.58	1.00e-30	128.00
IUUC-Mtr-058761	Medicago truncatula	31.64	6.00e-33	136.00
IUUC-Mla-058840	Melampsora laricipopulina	36.73	1.00e-24	108.00
IUUC-Mga-060129	Meleagris gallopavo	62.39	0.00e+00	759.00
IUUC-Mvi-060424	Microbotryum violaceum	35.85	1.00e-24	108.00
IUUC-Mmr-061295	Microcebus murinus	80.81	0.00e+00	1130.00
IUUC-Mdo-062295	Monodelphis domestica	70.32	0.00e+00	951.00
IUUC-Mmu-064009	Mus musculus	92.58	0.00e+00	1337.00
IUUC-Mac-065479	Musa acuminata	35.63	3.00e-24	107.00
IUUC-Mpu-065875	Mustela putorius furo	80.33	0.00e+00	1111.00
IUUC-Mlu-066941	Myotis lucifugus	79.02	0.00e+00	1027.00
IUUC-Nfi-068518	Neosartorya fischeri	31.88	2.00e-35	143.00
IUUC-Ncr-068886	Neurospora crassa	28.61	7.00e-32	132.00
IUUC-Nle-069717	Nomascus leucogenys	97.05	0.00e+00	1003.00
IUUC-Opr-070280	Ochotona princeps	94.62	0.00e+00	693.00
IUUC-Ont-071462	Oreochromis niloticus	66.31	4.00e-140	493.00
IUUC-Oan-073300	Ornithorhynchus anatinus	67.36	0.00e+00	855.00
IUUC-Ocu-074124	Oryctolagus cuniculus	80.15	0.00e+00	1176.00
IUUC-Oba-075756	Oryza barthii	30.75	4.00e-30	126.00
IUUC-Obr-076580	Oryza brachyantha	29.26	1.00e-33	138.00
IUUC-Ogl-077759	Oryza glaberrima	32.35	3.00e-36	147.00
IUUC-Ogu-078657	Oryza glumaepatula	29.97	5.00e-30	126.00
IUUC-Oin-079481	Oryza indica	32.47	2.00e-31	131.00
IUUC-Olo-081062	Oryza longistaminata	36.31	8.00e-23	102.00
IUUC-Ome-081813	Oryza meridionalis	29.84	2.00e-29	124.00
IUUC-Oni-083007	Oryza nivara	30.83	1.00e-29	125.00
IUUC-Opu-083385	Oryza punctata	29.84	1.00e-29	125.00
IUUC-Oru-084861	Oryza rufipogon	30.83	1.00e-29	125.00
IUUC-Osa-085896	Oryza sativa	32.18	3.00e-36	145.00
IUUC-Ola-086693	Oryzias latipes	62.67	2.00e-126	446.00
IUUC-Olu-087631	Ostreococcus lucimarinus	47.30	2.00e-14	70.10
IUUC-Oga-088262	Otolemur garnettii	79.93	0.00e+00	1117.00
IUUC-Oar-089658	Ovis aries	79.96	0.00e+00	1189.00
IUUC-Ptr-091311	Pan troglodytes	80.30	0.00e+00	1132.00
IUUC-Pan-091925	Papio anubis	80.20	0.00e+00	1177.00
IUUC-Psi-093605	Pelodiscus sinensis	65.18	0.00e+00	790.00
IUUC-Pma-094163	Petromyzon marinus	72.81	2.00e-98	351.00
IUUC-Pno-094790	Phaeosphaeria nodorum	30.09	4.00e-25	109.00
IUUC-Ppa-095943	Physcomitrella patens	30.41	1.00e-44	175.00
IUUC-Pfo-096581	Poecilia formosa	69.71	3.00e-134	473.00
IUUC-Pab-098229	Pongo abelii	79.76	0.00e+00	1131.00
IUUC-Pop-099160	Populus trichocarpa	30.67	5.00e-40	159.00
IUUC-Pca-100875	Procavia capensis	74.24	0.00e+00	715.00
IUUC-Ppe-101658	Prunus persica	36.90	3.00e-17	84.30
IUUC-Pva-102343	Pteropus vampyrus	92.34	0.00e+00	960.00
IUUC-Pgr-103275	Puccinia graminis	36.24	5.00e-18	86.70
IUUC-Ptt-104004	Puccinia triticina	40.00	3.00e-10	60.10
IUUC-Pte-104161	Pyrenophora teres	31.99	7.00e-30	125.00
IUUC-Pyt-104576	Pyrenophora triticirepentis	32.41	3.00e-30	126.00
IUUC-Sce-106138	Saccharomyces cerevisiae	30.92	4.00e-38	152.00
IUUC-Sha-107497	Sarcophilus harrisii	69.68	0.00e+00	964.00
IUUC-Sja-107991	Schizosaccharomyces japonicus	32.83	7.00e-44	171.00
IUUC-Spo-108257	Schizosaccharomyces pombe	33.63	1.00e-46	180.00
IUUC-Ssl-108581	Sclerotinia sclerotiorum	29.74	2.00e-37	150.00
IUUC-Smo-109358	Selaginella moellendorffii	29.95	3.00e-34	139.00
IUUC-Sit-109920	Setaria italica	32.80	3.00e-37	150.00
IUUC-Sly-111616	Solanum lycopersicum	38.10	1.00e-26	115.00
IUUC-Stu-112648	Solanum tuberosum	32.37	3.00e-11	63.20
IUUC-Sar-113120	Sorex araneus	73.43	0.00e+00	968.00
IUUC-Sbi-113881	Sorghum bicolor	30.40	4.00e-38	153.00
IUUC-Sre-115127	Sporisorium reilianum	30.96	3.00e-47	182.00
IUUC-Ssc-116147	Sus scrofa	81.40	0.00e+00	1135.00
IUUC-Tgu-117215	Taeniopygia guttata	75.59	0.00e+00	674.00
IUUC-Tru-118525	Takifugu rubripes	64.10	3.00e-133	468.00
IUUC-Tsy-119160	Tarsius syrichta	81.77	0.00e+00	1148.00
IUUC-Tni-119816	Tetraodon nigroviridis	68.98	1.00e-82	299.00
IUUC-Tca-121727	Theobroma cacao	30.56	6.00e-32	132.00
IUUC-Tre-122181	Trichoderma reesei	28.92	2.00e-35	144.00
IUUC-Tvi-122316	Trichoderma virens	28.27	2.00e-35	143.00
IUUC-Tae-125227	Triticum aestivum	30.05	2.00e-27	117.00
IUUC-Tur-126827	Triticum urartu	36.31	2.00e-16	81.30
IUUC-Tme-126984	Tuber melanosporum	30.46	1.00e-44	174.00
IUUC-Tbe-127263	Tupaia belangeri	76.00	0.00e+00	832.00
IUUC-Ttr-128498	Tursiops truncatus	79.11	0.00e+00	1174.00
IUUC-Uma-129457	Ustilago maydis	30.63	4.00e-45	176.00
IUUC-Vda-129986	Verticillium dahliae	28.95	9.00e-35	141.00
IUUC-Vpa-130795	Vicugna pacos	90.85	0.00e+00	796.00
IUUC-Vvi-131146	Vitis vinifera	36.31	7.00e-17	82.80
IUUC-Xtr-132789	Xenopus tropicalis	66.09	0.00e+00	673.00
IUUC-Xma-133011	Xiphophorus maculatus	69.01	1.00e-132	467.00
IUUC-Yli-134516	Yarrowia lipolytica	32.49	9.00e-40	157.00
IUUC-Zma-134699	Zea mays	30.00	1.00e-36	148.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence