iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020093

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Angio-associated migratory cell protein

Genbank Nucleotide ID

AY197355

Gene Name

AAMP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000014625.3	ENSCAFT00000023220.3	ENSCAFP00000021562.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.80e-32	109.7	91	128
UBD/Beta-Prp	7.60e-49	166.8	90	300

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sdtllvsGsdDgtikvWDlrtgvll 36
           H++sv+c+++   ++tl v+G+ D +  vW+l++g ll
   Q: 91   HSASVFCVSLdpkTNTLAVTGGEDDKAFVWRLSDGELL 128
           99*********8655999**************999875 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkf.spdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghe 94
            h  sv  cv    + ++l +tg++d++  vw++++g ll +  gh++ vt+  fs+d+ + +tg   +++kvw ++t + v +++   
   Q: 90   LHSASVF-CVSLdPKTNTLAVTGGEDDKAFVWRLSDGELLFECAGHKDSVTCAGFSHDSTLVATGDMSGLLKVWQVDTKEEVWSFE--A 175
           4444455.577735556666899************************************999************************..8 PP
   S: 95   dsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl..tgghtd 181
            ++  ++++p   +l++G++d    +w++++g c   t++g +   +c +v pdg+  v G  D+t+r+Wdlk+g+ ++ l  t+gh++
   Q: 176  GDLEWMEWHPRAPVLLAGTADGNTWMWKVPNGDCK--TFQGPNCPATCGRVLPDGKRAVVGYEDGTIRIWDLKQGSPIHVLkgTEGHQG 262
           9999******************************9..7*******************************************99677*** PP
   S: 182  svyslsfdsngkelvsgsldgtvklwdlqtgecvrtln 219
           + ++++ +++g  +++gs d + +l++  tg++v  ++
   Q: 263  PLTCVATNQDGSLILTGSVDCQAQLVSATTGKVVGVFR 300
           ********************************998765 PP

Organism

Canis familiaris

Functional Description
(View)

Plays a role in angiogenesis and cell migration. In smooth muscle cell migration, may act through the RhoA pathway (By similarity).

Protein Sequence
(Fasta)

MESESESGAA ADTPPLETLS FHGDEEIIEV VELDPGPPDP DDLAQEMEDV DFEEEEEEEE 60
GNEEGWVLEP QEGVVGSMEG PDDSEVTFAL HSASVFCVSL DPKTNTLAVT GGEDDKAFVW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGTCCG AATCGGAGAG CGGGGCCGCT GCTGACACCC CCCCCCTGGA GACCCTGAGC 60
TTCCATGGTG ATGAAGAGAT TATCGAGGTG GTAGAGCTGG ATCCTGGCCC GCCCGACCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0037--Angiogenesis
KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0217--Developmental protein
KW-0221--Differentiation
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0009986--C:cell surface
GO:0005829--C:cytosol
GO:0045171--C:intercellular bridge
GO:0015630--C:microtubule cytoskeleton
GO:0005886--C:plasma membrane
GO:0030687--C:preribosome, large subunit precursor
GO:0051082--F:unfolded protein binding
GO:0001525--P:angiogenesis
GO:0030154--P:cell differentiation
GO:0010595--P:positive regulation of endothelial cell migration
GO:0042273--P:ribosomal large subunit biogenesis
GO:0014909--P:smooth muscle cell migration

KEGG

cfa:478908

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000794	Aegilops tauschii	34.62	7.00e-57	215.00
IUUC-Aml-001781	Ailuropoda melanoleuca	97.94	0.00e+00	753.00
IUUC-Atr-003169	Amborella trichopoda	35.53	6.00e-61	227.00
IUUC-Apl-003939	Anas platyrhynchos	66.96	5.00e-115	407.00
IUUC-Aca-004594	Anolis carolinensis	78.05	1.00e-175	609.00
IUUC-Aly-006277	Arabidopsis lyrata	30.97	1.00e-47	183.00
IUUC-Ath-007701	Arabidopsis thaliana	33.14	7.00e-56	211.00
IUUC-Ame-011651	Astyanax mexicanus	55.37	1.00e-131	462.00
IUUC-Bgr-012118	Blumeria graminis	21.85	1.00e-16	81.30
IUUC-Bta-012833	Bos taurus	97.01	0.00e+00	754.00
IUUC-Bdi-014289	Brachypodium distachyon	34.93	6.00e-62	231.00
IUUC-Bol-015313	Brassica oleracea	32.00	7.00e-53	201.00
IUUC-Bra-017115	Brassica rapa	31.14	6.00e-43	167.00
IUUC-Cel-018305	Caenorhabditis elegans	31.82	5.00e-38	151.00
IUUC-Cja-019433	Callithrix jacchus	95.86	0.00e+00	756.00
IUUC-Cpo-021742	Cavia porcellus	98.85	0.00e+00	762.00
IUUC-Cre-022781	Chlamydomonas reinhardtii	33.24	2.00e-42	166.00
IUUC-Csa-023498	Chlorocebus sabaeus	96.09	0.00e+00	755.00
IUUC-Cho-024628	Choloepus hoffmanni	96.66	9.00e-178	615.00
IUUC-Cin-025244	Ciona intestinalis	45.87	2.00e-84	306.00
IUUC-Csv-026218	Ciona savignyi	46.15	2.00e-87	316.00
IUUC-Cne-026911	Cryptococcus neoformans	26.72	2.00e-25	110.00
IUUC-Dre-028528	Danio rerio	64.69	2.00e-139	488.00
IUUC-Dno-029297	Dasypus novemcinctus	94.05	0.00e+00	756.00
IUUC-Dor-030543	Dipodomys ordii	96.45	5.00e-66	244.00
IUUC-Dme-031587	Drosophila melanogaster	31.27	2.00e-45	176.00
IUUC-Ete-033100	Echinops telfairi	97.02	3.00e-125	441.00
IUUC-Eca-034277	Equus caballus	98.82	0.00e+00	741.00
IUUC-Eeu-035052	Erinaceus europaeus	97.58	1.00e-106	380.00
IUUC-Fca-036115	Felis catus	99.08	0.00e+00	767.00
IUUC-Fal-036864	Ficedula albicollis	82.09	1.00e-177	615.00
IUUC-Gmo-039090	Gadus morhua	60.22	3.00e-98	351.00
IUUC-Gga-040545	Gallus gallus	79.14	0.00e+00	640.00
IUUC-Gac-042027	Gasterosteus aculeatus	62.70	2.00e-140	492.00
IUUC-Gma-044168	Glycine max	35.92	4.00e-58	218.00
IUUC-Ggo-045036	Gorilla gorilla	96.09	0.00e+00	754.00
IUUC-Hsa-046749	Homo sapiens	96.09	0.00e+00	754.00
IUUC-Hvu-047217	Hordeum vulgare	34.67	1.00e-58	220.00
IUUC-Itr-048114	Ictidomys tridecemlineatus	98.62	0.00e+00	759.00
IUUC-Kpa-049147	Komagataella pastoris	25.20	1.00e-24	107.00
IUUC-Lch-049747	Latimeria chalumnae	61.37	7.00e-143	500.00
IUUC-Lpe-051433	Leersia perrieri	32.42	4.00e-53	201.00
IUUC-Loc-052406	Lepisosteus oculatus	68.42	9.00e-160	556.00
IUUC-Lma-053153	Leptosphaeria maculans	27.75	6.00e-15	75.50
IUUC-Laf-053901	Loxodonta africana	98.62	0.00e+00	762.00
IUUC-Mcc-054990	Macaca mulatta	98.91	0.00e+00	709.00
IUUC-Meu-056844	Macropus eugenii	87.86	0.00e+00	668.00
IUUC-Mtr-057759	Medicago truncatula	35.73	4.00e-59	222.00
IUUC-Mla-058856	Melampsora laricipopulina	29.44	9.00e-37	147.00
IUUC-Mga-059749	Meleagris gallopavo	81.20	3.00e-177	614.00
IUUC-Mvi-060237	Microbotryum violaceum	31.15	3.00e-44	172.00
IUUC-Mmr-061270	Microcebus murinus	94.69	0.00e+00	748.00
IUUC-Mdo-062965	Monodelphis domestica	87.14	0.00e+00	667.00
IUUC-Mmu-064081	Mus musculus	97.48	0.00e+00	760.00
IUUC-Mac-065236	Musa acuminata	33.43	3.00e-56	212.00
IUUC-Mpu-066355	Mustela putorius furo	99.54	0.00e+00	769.00
IUUC-Mlu-067630	Myotis lucifugus	98.17	0.00e+00	754.00
IUUC-Nle-069701	Nomascus leucogenys	97.70	0.00e+00	761.00
IUUC-Opr-070337	Ochotona princeps	92.18	0.00e+00	696.00
IUUC-Ont-072614	Oreochromis niloticus	69.43	2.00e-147	515.00
IUUC-Ocu-073912	Oryctolagus cuniculus	97.94	0.00e+00	751.00
IUUC-Oba-075195	Oryza barthii	32.44	7.00e-54	204.00
IUUC-Obr-076059	Oryza brachyantha	31.61	3.00e-55	209.00
IUUC-Ogl-077318	Oryza glaberrima	32.18	5.00e-56	211.00
IUUC-Ogu-078579	Oryza glumaepatula	32.05	7.00e-54	204.00
IUUC-Oin-079340	Oryza indica	32.18	5.00e-56	211.00
IUUC-Olo-080813	Oryza longistaminata	32.64	3.00e-54	206.00
IUUC-Ome-081420	Oryza meridionalis	32.74	5.00e-54	204.00
IUUC-Oni-082650	Oryza nivara	32.44	7.00e-54	204.00
IUUC-Opu-083832	Oryza punctata	32.74	2.00e-55	209.00
IUUC-Oru-084207	Oryza rufipogon	32.44	7.00e-54	204.00
IUUC-Osa-085708	Oryza sativa	32.18	5.00e-56	211.00
IUUC-Ola-087164	Oryzias latipes	65.09	6.00e-149	520.00
IUUC-Olu-087824	Ostreococcus lucimarinus	37.60	6.00e-51	194.00
IUUC-Oga-088864	Otolemur garnettii	98.39	0.00e+00	753.00
IUUC-Oar-090115	Ovis aries	96.09	0.00e+00	756.00
IUUC-Ptr-091398	Pan troglodytes	97.47	0.00e+00	759.00
IUUC-Pan-092002	Papio anubis	96.32	0.00e+00	756.00
IUUC-Psi-093979	Pelodiscus sinensis	79.23	2.00e-89	322.00
IUUC-Pma-094618	Petromyzon marinus	55.01	2.00e-129	455.00
IUUC-Ppa-095351	Physcomitrella patens	37.71	1.00e-66	247.00
IUUC-Pfo-097078	Poecilia formosa	72.29	4.00e-150	524.00
IUUC-Pab-098540	Pongo abelii	97.70	0.00e+00	761.00
IUUC-Pop-099140	Populus trichocarpa	36.34	2.00e-58	219.00
IUUC-Pca-101072	Procavia capensis	89.89	0.00e+00	704.00
IUUC-Ppe-101979	Prunus persica	34.30	4.00e-59	221.00
IUUC-Pva-102400	Pteropus vampyrus	91.03	0.00e+00	681.00
IUUC-Pgr-103362	Puccinia graminis	30.43	2.00e-43	170.00
IUUC-Ptt-103756	Puccinia triticina	31.93	1.00e-32	133.00
IUUC-Rno-105672	Rattus norvegicus	98.39	0.00e+00	772.00
IUUC-Sja-107693	Schizosaccharomyces japonicus	28.81	1.00e-43	170.00
IUUC-Spo-108208	Schizosaccharomyces pombe	29.10	1.00e-46	180.00
IUUC-Smo-109168	Selaginella moellendorffii	34.99	7.00e-58	217.00
IUUC-Sit-109978	Setaria italica	32.76	1.00e-55	210.00
IUUC-Sly-111316	Solanum lycopersicum	36.00	6.00e-60	224.00
IUUC-Stu-111956	Solanum tuberosum	37.32	5.00e-62	231.00
IUUC-Sbi-114189	Sorghum bicolor	33.05	7.00e-54	204.00
IUUC-Sre-115029	Sporisorium reilianum	33.43	4.00e-41	162.00
IUUC-Ssc-116045	Sus scrofa	85.82	2.00e-168	585.00
IUUC-Tgu-117514	Taeniopygia guttata	81.54	4.00e-176	610.00
IUUC-Tru-117851	Takifugu rubripes	67.14	4.00e-142	497.00
IUUC-Tsy-119140	Tarsius syrichta	92.41	0.00e+00	697.00
IUUC-Tni-120248	Tetraodon nigroviridis	67.71	1.00e-142	499.00
IUUC-Tca-121686	Theobroma cacao	32.59	8.00e-56	211.00
IUUC-Tae-123968	Triticum aestivum	34.67	7.00e-59	221.00
IUUC-Tur-126174	Triticum urartu	34.91	7.00e-57	214.00
IUUC-Tme-127079	Tuber melanosporum	27.92	2.00e-13	70.90
IUUC-Tbe-127476	Tupaia belangeri	98.07	6.00e-107	380.00
IUUC-Ttr-128182	Tursiops truncatus	97.24	0.00e+00	761.00
IUUC-Uma-129624	Ustilago maydis	32.84	3.00e-44	172.00
IUUC-Vpa-130605	Vicugna pacos	89.34	1.00e-172	598.00
IUUC-Vvi-131319	Vitis vinifera	34.01	3.00e-57	215.00
IUUC-Xtr-132193	Xenopus tropicalis	71.57	2.00e-169	588.00
IUUC-Xma-133880	Xiphophorus maculatus	71.43	7.00e-150	523.00
IUUC-Yli-134520	Yarrowia lipolytica	28.77	5.00e-27	115.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence