iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000009781.2	ENSCJAT00000019018.1	ENSCJAP00000017991.1
ENSCJAG00000009781.2	ENSCJAT00000019149.2	ENSCJAP00000018119.2
ENSCJAG00000009781.2	ENSCJAT00000019138.2	ENSCJAP00000018108.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.80e-54	178.4	2110	2145
UBD/Beta-Prp	1.50e-98	330.6	1936	2179

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sdtllvsGsdDgtikvWDlrtgvll 36
           H d+vt++a+  d+ll+s+s Dg++ +WD+ +g +l
   Q: 2110 HRDWVTGCAWtKDNLLISCSSDGSVGLWDPESGQQL 2145
           9*********877****************9999775 PP

UBD/Beta-Prp

   S: 57   avkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee.tlsghdgvvnc 142
           +v +spdg+  + g + + ik++ +s+g++    ++ +  v +l++   +++lvsG +d  ++ w l++ +  +  +ls h++ v +
   Q: 1936 SVALSPDGDQVAVGYRADGIKIYKISSGSQGAQGQALDVAVSALAWLN-SKVLVSGAEDGSLQGWALKECYLQSLwLLSTHQKPVLG 2021
           466677777777777777777777777777777777777777777776.67777777777777776666555444677777777777 PP
   S: 143  vvvhpdgnllvsGslDrtvrlWdl.........ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec...vrt 217
           +++++  +ll+s+s D tv lW           +   + ++l+g h+++v + sf+ +g +l++g++d+ +  wd++t +    +r+
   Q: 2022 LATSQ--QLLASASEDFTVWLWPRqlltlphkaEDFPCGTELRG-HEGPVSCCSFSTDGGSLATGGRDRGLLCWDVRTPKApvlIRS 2105
           77777..7777777777777777655555555444445555566.777777777777777777777777777777776666566677 PP
   S: 218  lng.htdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwkl 294
           + + h+d+v+  + + +d++l+s+ssDgs+ +Wd +sg+ l+++ +h+s v++va+    + ++v+++ d+++++w+ 
   Q: 2106 FPAcHRDWVTGCAWT-KDNLLISCSSDGSVGLWDPESGQQLGQFLGHQSAVSAVAA---VGEHVVSVGRDGTLKVWDH 2179
           665577777777666.7777777777777777777777777777777777777777...6677777777777777764 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MEKLHGHVSA DPDILSLENR CLAMLPDLHP MEKLHEHISP HSDILSLKNQ CLAMLPDLKT 60
MEKPHGHVSA HPDILSLENR CLATLPNLKT LEKPHGHVSA HPDILSLENR CLATLPSLKS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAATCGGACG CCCCTGGTCA CGCACCACTG TCTCCCGCCC CAGTCTAAGG GAGGATTCGA 60
GCGCAGGTAG AACTTCCCCT GGCCCTGGGT CTAGGGCGCT GGGCTCGGAG GCTGAAAGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR003143--Cyt_cd1_C
IPR025139--DUF4062
IPR007111--NACHT_NTPase
IPR027417--P-loop_NTPase
IPR023302--Pept_S9A_N
IPR008850--TEP1_N
IPR008858--TROVE_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50837--NACHT
PS51226--TEP1_N
PS50988--TROVE
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13271--DUF4062
PF05386--TEP1_N
PF05731--TROVE
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0005697--C:telomerase holoenzyme complex
GO:0003720--F:telomerase activity
GO:0070034--F:telomerase RNA binding
GO:0000722--P:telomere maintenance via recombination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001482	Ailuropoda melanoleuca	78.73	0.00e+00	3877.00
IUUC-Aca-005102	Anolis carolinensis	42.32	0.00e+00	1670.00
IUUC-Ame-011165	Astyanax mexicanus	32.18	0.00e+00	783.00
IUUC-Bta-012323	Bos taurus	79.34	0.00e+00	3914.00
IUUC-Cfa-020803	Canis familiaris	71.93	0.00e+00	3421.00
IUUC-Cpo-022312	Cavia porcellus	74.66	0.00e+00	3523.00
IUUC-Csa-023287	Chlorocebus sabaeus	92.32	0.00e+00	4712.00
IUUC-Dre-028825	Danio rerio	35.50	0.00e+00	1177.00
IUUC-Dno-029455	Dasypus novemcinctus	77.96	0.00e+00	3752.00
IUUC-Dor-030328	Dipodomys ordii	73.50	0.00e+00	2575.00
IUUC-Ete-032385	Echinops telfairi	72.90	0.00e+00	1918.00
IUUC-Eca-033726	Equus caballus	81.96	0.00e+00	4111.00
IUUC-Eeu-034665	Erinaceus europaeus	63.43	0.00e+00	975.00
IUUC-Fca-035365	Felis catus	79.64	0.00e+00	3954.00
IUUC-Gmo-039584	Gadus morhua	31.43	7.00e-122	432.00
IUUC-Gac-042307	Gasterosteus aculeatus	35.80	0.00e+00	1038.00
IUUC-Ggo-045432	Gorilla gorilla	90.18	0.00e+00	4440.00
IUUC-Hsa-046182	Homo sapiens	92.41	0.00e+00	4747.00
IUUC-Itr-049021	Ictidomys tridecemlineatus	79.77	0.00e+00	4002.00
IUUC-Lch-050186	Latimeria chalumnae	39.47	8.00e-80	291.00
IUUC-Laf-054524	Loxodonta africana	77.89	0.00e+00	3931.00
IUUC-Mcc-055628	Macaca mulatta	92.51	0.00e+00	4708.00
IUUC-Meu-056338	Macropus eugenii	63.38	0.00e+00	1318.00
IUUC-Mmr-060854	Microcebus murinus	82.89	0.00e+00	4135.00
IUUC-Mdo-062247	Monodelphis domestica	59.98	0.00e+00	2794.00
IUUC-Mmu-064406	Mus musculus	74.15	0.00e+00	3659.00
IUUC-Mpu-065806	Mustela putorius furo	77.61	0.00e+00	3886.00
IUUC-Mlu-068116	Myotis lucifugus	80.18	0.00e+00	3889.00
IUUC-Nle-069628	Nomascus leucogenys	90.95	0.00e+00	4149.00
IUUC-Opr-070242	Ochotona princeps	78.43	0.00e+00	2843.00
IUUC-Oan-073598	Ornithorhynchus anatinus	52.10	0.00e+00	1939.00
IUUC-Ocu-073933	Oryctolagus cuniculus	79.45	0.00e+00	3882.00
IUUC-Ola-086886	Oryzias latipes	34.78	0.00e+00	1074.00
IUUC-Oga-088609	Otolemur garnettii	80.36	0.00e+00	3978.00
IUUC-Oar-089957	Ovis aries	78.48	0.00e+00	3817.00
IUUC-Ptr-090577	Pan troglodytes	90.89	0.00e+00	4650.00
IUUC-Pan-092397	Papio anubis	92.23	0.00e+00	4695.00
IUUC-Pma-094373	Petromyzon marinus	35.98	6.00e-76	278.00
IUUC-Pfo-096497	Poecilia formosa	35.83	0.00e+00	1077.00
IUUC-Pab-098028	Pongo abelii	91.65	0.00e+00	4649.00
IUUC-Pca-101002	Procavia capensis	82.34	0.00e+00	1885.00
IUUC-Pva-102144	Pteropus vampyrus	73.29	0.00e+00	1705.00
IUUC-Rno-105828	Rattus norvegicus	73.44	0.00e+00	3690.00
IUUC-Sha-106469	Sarcophilus harrisii	60.33	0.00e+00	2898.00
IUUC-Sar-113035	Sorex araneus	76.80	0.00e+00	1456.00
IUUC-Ssc-116122	Sus scrofa	81.66	0.00e+00	2964.00
IUUC-Tru-118412	Takifugu rubripes	32.90	0.00e+00	1159.00
IUUC-Tsy-119257	Tarsius syrichta	76.92	0.00e+00	1616.00
IUUC-Tni-120032	Tetraodon nigroviridis	33.44	1.00e-39	157.00
IUUC-Tbe-127312	Tupaia belangeri	67.22	0.00e+00	1003.00
IUUC-Ttr-128335	Tursiops truncatus	80.49	0.00e+00	3453.00
IUUC-Xtr-132524	Xenopus tropicalis	39.48	0.00e+00	1415.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence