iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cre-022702

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin-activating enzyme E1

Genbank Nucleotide ID

DS496132

Gene Name

UBA1; CHLREDRAFT_191903

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CHLREDRAFT_191903	EDP01888	EDP01888

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	2.00e-162	540.6	443	943

Active Site

Position(s)	Description	Evidence
632	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.............gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdv 88
           YD Qi+++G + q++l++ + +lvGag+lGcE+lKn++ +Gv             g +tv+D+d +e+snl+rqFLfr++d+g sK+ vaa+a++++np  
   Q: 443  YDPQIAVFGRTMQRRLSQLQLFLVGAGALGCEFLKNFACMGVacgplpgadaastGRLTVTDDDVIEKSNLSRQFLFRDWDIGSSKSSVAAAAAQRINPGL 543
           9**************************************************************************************************** PP
   S: 89   nveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaeht 186
            v++ ++++++++e+++   F + +d+Vv+aldn+ ar++v+++c++  +pl+esgtlG + +++ +i+ lte y +s+dpp+k++P+ct+ ++p +++h+
   Q: 544  AVTPLQNRVSPDTESVFddkFWQGLDLVVNALDNVNARLYVDSRCVYFGKPLLESGTLGPKCNTQMVIPRLTENYGASRDPPEKQAPMCTVHSFPHNIDHC 644
           ***************9999999******************************************************************************* PP
   S: 187  iewa.............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikqllksfecdivtkskspfwv 274
           ++wa             + ++ l+++ + ++ v+++ d+++ ++ +  v + l + +  +f+ ++++a+  f+ +++n i ql+  f+ d  t+ ++pfw+
   Q: 645  LTWArsefegllekaprEAASFLAAPADYAKAVRANPDASARQQLEA-VAEVLLDGRAADFNACVAWARGRFQDYFHNRIAQLTYTFPEDATTSTGAPFWS 744
           ****************9666666666666666666655444444444.445577778889***************************************** PP
   S: 275  .................................................................sfcsnaealqvpekvekdeevvkasaplylllrale 310
                                                                            + ++  +a ++++ ++++++ ++a   ++ ll +le
   Q: 745  apkrfprplnfdpkdpahaafvqagailraevfgiprpdwadsaakvaevaaavdipafvpragvQIETDPKADRTKPAGADKTHDDEAV--IEGLLGRLE 843
           ******************************************999888888888777766666666666666666666666665544333..555555555 PP
   S: 311  rfe...kkkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsg..kfeplknfflfdae 404
            +    +k+g k + ++fekddd   ++dl++ +an+ra +++i++ +d+ + k iag+iipaiat +av  Gl+++E++K+v    k e+++n+f ++a+
   Q: 844  GAVpglAKEGFKLSPIQFEKDDDGnfHMDLIAGLANMRARNYSIPE-VDKLKAKLIAGRIIPAIATATAVATGLVCLELYKAVLPgkKLEAYRNTFANLAL 943
           442222667777778********99*********************.************************************8878*********99875 PP

Organism

Chlamydomonas reinhardtii

Protein Sequence
(Fasta)

MSKRTADGST ETPSAKKTAT TMSAKGGAAD GAHVEIDENL HSRQLAVYGR EAMKRMATSS 60
VLICGANGLG VEVAKNVILA GVRGVTVHDT AKVALTDLSA QFYLTEQDVG RNRAEACREK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTCATCAAT CATACATTAC GTCGATTCTC TCGTCAATTT CCTTCGCACA CTTTGTGCCG 60
GTTGTCCCGG CACGCGATTG ATTACAATAG GCAGCGCGTG CACCGCGCTT ATGTCCAAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

KEGG

cre:CHLREDRAFT_191903

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000367	Aegilops tauschii	60.91	0.00e+00	1154.00
IUUC-Aml-001311	Ailuropoda melanoleuca	45.65	0.00e+00	862.00
IUUC-Atr-002684	Amborella trichopoda	60.29	0.00e+00	1207.00
IUUC-Apl-004158	Anas platyrhynchos	39.31	0.00e+00	627.00
IUUC-Aca-004620	Anolis carolinensis	44.29	0.00e+00	847.00
IUUC-Aly-005515	Arabidopsis lyrata	59.96	0.00e+00	1209.00
IUUC-Ath-006891	Arabidopsis thaliana	60.25	0.00e+00	1216.00
IUUC-Ago-007873	Ashbya gossypii	45.24	0.00e+00	796.00
IUUC-Acl-008181	Aspergillus clavatus	43.74	0.00e+00	775.00
IUUC-Afl-008455	Aspergillus flavus	45.10	0.00e+00	761.00
IUUC-Afu-009065	Aspergillus fumigatus	44.39	0.00e+00	809.00
IUUC-Ani-009371	Aspergillus nidulans	44.76	0.00e+00	778.00
IUUC-Ang-009737	Aspergillus niger	44.77	0.00e+00	776.00
IUUC-Aor-010007	Aspergillus oryzae	45.10	0.00e+00	761.00
IUUC-Ate-010466	Aspergillus terreus	44.32	0.00e+00	799.00
IUUC-Ame-010933	Astyanax mexicanus	46.77	0.00e+00	859.00
IUUC-Bgr-012281	Blumeria graminis	41.48	0.00e+00	751.00
IUUC-Bta-012767	Bos taurus	45.68	0.00e+00	865.00
IUUC-Bci-013721	Botrytis cinerea	44.98	0.00e+00	752.00
IUUC-Bdi-014843	Brachypodium distachyon	59.81	0.00e+00	1162.00
IUUC-Bol-015665	Brassica oleracea	60.73	0.00e+00	1208.00
IUUC-Bra-017252	Brassica rapa	59.18	0.00e+00	1195.00
IUUC-Cel-018260	Caenorhabditis elegans	39.25	0.00e+00	657.00
IUUC-Cja-019152	Callithrix jacchus	45.86	0.00e+00	860.00
IUUC-Cfa-020622	Canis familiaris	44.41	0.00e+00	822.00
IUUC-Cpo-022526	Cavia porcellus	45.67	0.00e+00	857.00
IUUC-Csa-023780	Chlorocebus sabaeus	45.40	0.00e+00	865.00
IUUC-Cho-024682	Choloepus hoffmanni	38.40	7.00e-87	313.00
IUUC-Cin-025790	Ciona intestinalis	44.73	0.00e+00	839.00
IUUC-Csv-026084	Ciona savignyi	43.73	0.00e+00	818.00
IUUC-Cgl-026512	Colletotrichum gloeosporioides	45.33	0.00e+00	809.00
IUUC-Cne-026960	Cryptococcus neoformans	44.09	0.00e+00	781.00
IUUC-Cme-027290	Cyanidioschyzon merolae	40.55	0.00e+00	652.00
IUUC-Dre-028149	Danio rerio	46.20	0.00e+00	877.00
IUUC-Dno-028884	Dasypus novemcinctus	45.40	0.00e+00	863.00
IUUC-Dor-030229	Dipodomys ordii	43.95	0.00e+00	813.00
IUUC-Dse-031524	Dothistroma septosporum	43.66	0.00e+00	769.00
IUUC-Dme-032045	Drosophila melanogaster	44.36	0.00e+00	824.00
IUUC-Ete-033124	Echinops telfairi	42.98	9.00e-133	466.00
IUUC-Eca-033330	Equus caballus	45.59	0.00e+00	864.00
IUUC-Eeu-035323	Erinaceus europaeus	39.26	1.00e-133	469.00
IUUC-Fca-036255	Felis catus	45.59	0.00e+00	860.00
IUUC-Fal-036848	Ficedula albicollis	39.75	0.00e+00	633.00
IUUC-Fox-038007	Fusarium oxysporum	44.77	7.00e-123	432.00
IUUC-Fso-038339	Fusarium solani	45.78	0.00e+00	795.00
IUUC-Gmo-039338	Gadus morhua	44.34	0.00e+00	827.00
IUUC-Ggr-039823	Gaeumannomyces graminis	45.24	0.00e+00	811.00
IUUC-Gga-040747	Gallus gallus	39.77	0.00e+00	631.00
IUUC-Gac-041773	Gasterosteus aculeatus	44.80	0.00e+00	823.00
IUUC-Gma-043198	Glycine max	60.19	0.00e+00	1197.00
IUUC-Ggo-045336	Gorilla gorilla	45.22	0.00e+00	846.00
IUUC-Hsa-045982	Homo sapiens	45.31	0.00e+00	848.00
IUUC-Hvu-047418	Hordeum vulgare	59.90	0.00e+00	1168.00
IUUC-Itr-048460	Ictidomys tridecemlineatus	45.59	0.00e+00	870.00
IUUC-Kpa-049112	Komagataella pastoris	44.71	0.00e+00	799.00
IUUC-Lch-050371	Latimeria chalumnae	45.60	0.00e+00	876.00
IUUC-Lpe-051299	Leersia perrieri	58.47	0.00e+00	1203.00
IUUC-Loc-052936	Lepisosteus oculatus	47.19	0.00e+00	894.00
IUUC-Lma-053315	Leptosphaeria maculans	43.76	0.00e+00	796.00
IUUC-Laf-053948	Loxodonta africana	44.93	0.00e+00	840.00
IUUC-Mcc-055843	Macaca mulatta	45.50	0.00e+00	863.00
IUUC-Meu-056258	Macropus eugenii	45.58	0.00e+00	848.00
IUUC-Mor-057269	Magnaporthe oryzae	45.32	0.00e+00	806.00
IUUC-Mpo-057435	Magnaporthe poae	45.10	0.00e+00	806.00
IUUC-Mtr-058572	Medicago truncatula	59.61	0.00e+00	1162.00
IUUC-Mla-059176	Melampsora laricipopulina	46.25	0.00e+00	801.00
IUUC-Mga-059721	Meleagris gallopavo	39.28	5.00e-177	613.00
IUUC-Mvi-060437	Microbotryum violaceum	43.93	0.00e+00	769.00
IUUC-Mmr-061405	Microcebus murinus	44.66	0.00e+00	830.00
IUUC-Mdo-062032	Monodelphis domestica	44.44	0.00e+00	817.00
IUUC-Mmu-063280	Mus musculus	44.84	0.00e+00	843.00
IUUC-Mac-065505	Musa acuminata	58.91	0.00e+00	1175.00
IUUC-Mpu-066409	Mustela putorius furo	45.59	0.00e+00	866.00
IUUC-Mlu-067217	Myotis lucifugus	45.12	0.00e+00	853.00
IUUC-Nfi-068407	Neosartorya fischeri	44.18	0.00e+00	788.00
IUUC-Ncr-068698	Neurospora crassa	45.22	0.00e+00	810.00
IUUC-Nle-070072	Nomascus leucogenys	43.16	0.00e+00	773.00
IUUC-Opr-070715	Ochotona princeps	36.99	8.00e-154	536.00
IUUC-Ont-071671	Oreochromis niloticus	45.74	0.00e+00	871.00
IUUC-Oan-073268	Ornithorhynchus anatinus	39.90	3.00e-169	587.00
IUUC-Ocu-074544	Oryctolagus cuniculus	45.50	0.00e+00	866.00
IUUC-Oba-075120	Oryza barthii	60.87	0.00e+00	1166.00
IUUC-Obr-076557	Oryza brachyantha	60.63	0.00e+00	1184.00
IUUC-Ogl-077887	Oryza glaberrima	60.87	0.00e+00	1169.00
IUUC-Ogu-078305	Oryza glumaepatula	58.69	0.00e+00	1191.00
IUUC-Oin-080154	Oryza indica	58.79	0.00e+00	1191.00
IUUC-Olo-081089	Oryza longistaminata	58.98	0.00e+00	1193.00
IUUC-Ome-081942	Oryza meridionalis	61.17	0.00e+00	1173.00
IUUC-Oni-082365	Oryza nivara	60.97	0.00e+00	1172.00
IUUC-Opu-083977	Oryza punctata	60.06	0.00e+00	1172.00
IUUC-Oru-084469	Oryza rufipogon	58.89	0.00e+00	1194.00
IUUC-Osa-085949	Oryza sativa	60.68	0.00e+00	1186.00
IUUC-Ola-087002	Oryzias latipes	45.83	0.00e+00	860.00
IUUC-Olu-087687	Ostreococcus lucimarinus	60.81	0.00e+00	1140.00
IUUC-Oga-088594	Otolemur garnettii	45.61	0.00e+00	843.00
IUUC-Oar-090068	Ovis aries	45.78	0.00e+00	862.00
IUUC-Ptr-090609	Pan troglodytes	38.91	0.00e+00	632.00
IUUC-Pan-092114	Papio anubis	45.40	0.00e+00	862.00
IUUC-Psi-093489	Pelodiscus sinensis	39.39	0.00e+00	639.00
IUUC-Pma-094214	Petromyzon marinus	49.40	4.00e-37	145.00
IUUC-Pno-095154	Phaeosphaeria nodorum	43.08	0.00e+00	798.00
IUUC-Ppa-095227	Physcomitrella patens	62.60	0.00e+00	1238.00
IUUC-Pfo-097184	Poecilia formosa	45.74	0.00e+00	875.00
IUUC-Pab-097861	Pongo abelii	45.31	0.00e+00	836.00
IUUC-Pop-098934	Populus trichocarpa	58.02	0.00e+00	1207.00
IUUC-Pca-100347	Procavia capensis	43.46	0.00e+00	678.00
IUUC-Ppe-102012	Prunus persica	58.51	0.00e+00	1202.00
IUUC-Pva-102584	Pteropus vampyrus	45.59	0.00e+00	885.00
IUUC-Pgr-103336	Puccinia graminis	45.27	0.00e+00	769.00
IUUC-Ptt-103939	Puccinia triticina	45.13	0.00e+00	761.00
IUUC-Pte-104200	Pyrenophora teres	44.36	0.00e+00	808.00
IUUC-Pyt-104441	Pyrenophora triticirepentis	43.79	0.00e+00	803.00
IUUC-Rno-105462	Rattus norvegicus	45.42	0.00e+00	844.00
IUUC-Sce-106245	Saccharomyces cerevisiae	43.76	0.00e+00	787.00
IUUC-Sha-107142	Sarcophilus harrisii	44.94	0.00e+00	857.00
IUUC-Sja-107841	Schizosaccharomyces japonicus	42.21	0.00e+00	774.00
IUUC-Spo-108034	Schizosaccharomyces pombe	42.29	0.00e+00	748.00
IUUC-Ssl-108497	Sclerotinia sclerotiorum	44.41	0.00e+00	770.00
IUUC-Smo-109211	Selaginella moellendorffii	60.77	0.00e+00	1238.00
IUUC-Sit-110281	Setaria italica	61.26	0.00e+00	1189.00
IUUC-Sly-110914	Solanum lycopersicum	59.22	0.00e+00	1188.00
IUUC-Stu-112109	Solanum tuberosum	59.03	0.00e+00	1188.00
IUUC-Sar-113737	Sorex araneus	45.31	0.00e+00	856.00
IUUC-Sbi-114774	Sorghum bicolor	59.98	0.00e+00	1237.00
IUUC-Sre-115148	Sporisorium reilianum	44.90	0.00e+00	776.00
IUUC-Ssc-115777	Sus scrofa	45.45	0.00e+00	857.00
IUUC-Tgu-116565	Taeniopygia guttata	39.66	0.00e+00	635.00
IUUC-Tru-118742	Takifugu rubripes	45.45	0.00e+00	839.00
IUUC-Tsy-119436	Tarsius syrichta	33.56	3.00e-143	500.00
IUUC-Tni-120401	Tetraodon nigroviridis	45.64	0.00e+00	843.00
IUUC-Tca-121436	Theobroma cacao	59.48	0.00e+00	1199.00
IUUC-Tre-122009	Trichoderma reesei	44.08	0.00e+00	766.00
IUUC-Tvi-122259	Trichoderma virens	45.18	0.00e+00	766.00
IUUC-Tae-125113	Triticum aestivum	60.91	0.00e+00	1156.00
IUUC-Tur-126330	Triticum urartu	60.19	0.00e+00	1187.00
IUUC-Tme-127055	Tuber melanosporum	42.49	0.00e+00	728.00
IUUC-Tbe-127587	Tupaia belangeri	42.35	1.00e-135	475.00
IUUC-Ttr-128331	Tursiops truncatus	45.12	0.00e+00	849.00
IUUC-Uma-129387	Ustilago maydis	44.59	0.00e+00	772.00
IUUC-Vda-129977	Verticillium dahliae	45.99	0.00e+00	743.00
IUUC-Vpa-130716	Vicugna pacos	37.33	1.00e-171	595.00
IUUC-Vvi-130857	Vitis vinifera	60.21	0.00e+00	1210.00
IUUC-Xtr-132947	Xenopus tropicalis	36.03	4.00e-169	587.00
IUUC-Xma-133805	Xiphophorus maculatus	45.92	0.00e+00	859.00
IUUC-Yli-134547	Yarrowia lipolytica	43.60	0.00e+00	796.00
IUUC-Zma-135052	Zea mays	60.02	0.00e+00	1188.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence