iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Hvu-047418

Ensembl Protein ID

MLOC_80485.2

UniProt Accession

M0ZAT8; M0ZAT8_HORVV

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MLOC_80485	MLOC_80485.2	MLOC_80485.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.50e-171	572.3	440	928

Active Site

Position(s)	Description	Evidence
621	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnvea 92
           YD Qi ++G++ q kl+++k+++vG g+lGcE+lKnL+l+G+     g++tv+D+d +e+snl+rqFLfr++++g++K+ vaa a+  +np+ +vea
   Q: 440  YDAQISVFGSKFQSKLEQSKIFMVGSGALGCEFLKNLALMGIscsqnGKLTVTDDDVIEKSNLSRQFLFRDWNIGQPKSTVAATAAMAINPKLHVEA 536
           ************************************************************************************************* PP
   S: 93   heesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaeht 186
            +++ ++++e+++   F +++d Vv+aldn+ ar++++++c++ ++pl+esgtlG + +++ +i++lte y +s+dpp+k++P+ct+ ++p +++h+
   Q: 537  LQNRASPETENVFndaFWENLDAVVNALDNVTARMYIDSRCVYFQKPLLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQAPMCTVHSFPHNIDHC 633
           ***********99************************************************************************************ PP
   S: 187  iewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikqllksfecdivtksksp 271
           ++wa              +n +l++ ++ +  +     ++ ++ +++v + l + + e+f+++i++a+ +f+ +++n +kql+  f+ d +t+s++p
   Q: 634  LTWArsefegllektpTEVNGFLSNPSAYVVAARTAGDAQARDQLERVIECLHGDKCETFQDCITWARLKFEDYFSNRVKQLTFTFPEDSMTSSGAP 730
           *****99999999998777777777777666777777778888888888999999****************************************** PP
   S: 272  fwv...........................................................sfcsnaealqvpekvekdeevvkasap.lylllra 308
           fw+                                                             +++  ++ ++ek+++   ++ ++a+ ++ l+++
   Q: 731  FWSapkrfprplefsstdpsqlnfilaasilraetfgipipdwtktpnevaaaavdkvivpeFQPKQGVKIVTDEKATSISSASVDDAAvIEELITK 827
           *******************************************99999888888888777733344445555667777776666666669******* PP
   S: 309  lerfekk..kgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsg..kfeplknff 399
           le+ +k+  +g  ++ ++fekddd   ++d+++ +an+ra +++i++ +d+ + k iag+iipaiat +a+  Gl+++E++Kv+ g  k e ++n+f
   Q: 828  LEQISKTlpPGFHMKPIQFEKDDDTnfHMDVIAGFANMRARNYSIPE-VDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKVLAGghKVEDYRNTF 923
           *****976689************************************.**************************************999******** PP
   S: 400  lfdae 404
            ++a+
   Q: 924  ANLAI 928
           99876 PP

Organism

Hordeum vulgare

Protein Sequence
(Fasta)

MLPRKREIVA SEVENQQKKA RPADADDAMA MAGRPTEIDE DLHSRQLAVY GRETMKRLFA 60
SNVLVSGLQG LGAEIAKNLV LAGVKSVTLH DDGNVELWDL SSNFFLSEKD VGQNRAQACV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCACACGTA CACTTCGAGT TCCACTGTCA AGCGTGCCCA TAAGCCCCGT GCCCCACTTG 60
TCAAGCCACA CCCCTAGATA GCCGAACATC GCCAACATTT GCATAGTTGA GTGGCGACCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000367	Aegilops tauschii	98.03	0.00e+00	1930.00
IUUC-Aml-001311	Ailuropoda melanoleuca	45.81	0.00e+00	888.00
IUUC-Atr-002684	Amborella trichopoda	77.03	0.00e+00	1660.00
IUUC-Aca-004620	Anolis carolinensis	44.82	0.00e+00	874.00
IUUC-Aly-005418	Arabidopsis lyrata	78.32	0.00e+00	1691.00
IUUC-Ath-006891	Arabidopsis thaliana	77.90	0.00e+00	1674.00
IUUC-Ago-007873	Ashbya gossypii	45.44	0.00e+00	820.00
IUUC-Acl-008181	Aspergillus clavatus	45.50	0.00e+00	815.00
IUUC-Afl-008455	Aspergillus flavus	46.79	0.00e+00	811.00
IUUC-Afu-009065	Aspergillus fumigatus	46.09	0.00e+00	847.00
IUUC-Ani-009371	Aspergillus nidulans	46.40	0.00e+00	810.00
IUUC-Ang-009737	Aspergillus niger	46.71	0.00e+00	821.00
IUUC-Aor-010007	Aspergillus oryzae	46.79	0.00e+00	811.00
IUUC-Ate-010466	Aspergillus terreus	46.85	0.00e+00	860.00
IUUC-Ame-010933	Astyanax mexicanus	46.50	0.00e+00	843.00
IUUC-Bgr-012281	Blumeria graminis	44.64	0.00e+00	825.00
IUUC-Bta-012767	Bos taurus	46.11	0.00e+00	896.00
IUUC-Bci-013721	Botrytis cinerea	45.92	0.00e+00	804.00
IUUC-Bdi-014843	Brachypodium distachyon	93.51	0.00e+00	1900.00
IUUC-Bol-015665	Brassica oleracea	78.69	0.00e+00	1661.00
IUUC-Bra-017252	Brassica rapa	78.71	0.00e+00	1690.00
IUUC-Cja-019152	Callithrix jacchus	46.01	0.00e+00	890.00
IUUC-Cfa-020622	Canis familiaris	44.30	0.00e+00	842.00
IUUC-Cpo-022526	Cavia porcellus	46.32	0.00e+00	886.00
IUUC-Cre-022702	Chlamydomonas reinhardtii	60.39	0.00e+00	1182.00
IUUC-Csa-023780	Chlorocebus sabaeus	46.12	0.00e+00	896.00
IUUC-Cin-025790	Ciona intestinalis	44.19	0.00e+00	875.00
IUUC-Csv-026084	Ciona savignyi	43.05	0.00e+00	849.00
IUUC-Cgl-026512	Colletotrichum gloeosporioides	48.01	0.00e+00	899.00
IUUC-Cne-026960	Cryptococcus neoformans	45.24	0.00e+00	848.00
IUUC-Cme-027290	Cyanidioschyzon merolae	39.21	0.00e+00	691.00
IUUC-Dre-028149	Danio rerio	47.02	0.00e+00	872.00
IUUC-Dno-028884	Dasypus novemcinctus	45.68	0.00e+00	885.00
IUUC-Dor-030229	Dipodomys ordii	43.96	0.00e+00	839.00
IUUC-Dse-031524	Dothistroma septosporum	44.16	0.00e+00	811.00
IUUC-Dme-032045	Drosophila melanogaster	44.95	0.00e+00	851.00
IUUC-Ete-033124	Echinops telfairi	39.47	1.00e-131	462.00
IUUC-Eca-033330	Equus caballus	45.59	0.00e+00	885.00
IUUC-Fca-036255	Felis catus	45.54	0.00e+00	881.00
IUUC-Fal-036848	Ficedula albicollis	39.58	0.00e+00	686.00
IUUC-Fso-038339	Fusarium solani	46.96	0.00e+00	834.00
IUUC-Gmo-039338	Gadus morhua	44.42	0.00e+00	830.00
IUUC-Ggr-039823	Gaeumannomyces graminis	45.50	0.00e+00	870.00
IUUC-Gac-041773	Gasterosteus aculeatus	44.60	0.00e+00	844.00
IUUC-Gma-043165	Glycine max	81.29	0.00e+00	1722.00
IUUC-Ggo-045336	Gorilla gorilla	46.03	0.00e+00	877.00
IUUC-Hsa-045982	Homo sapiens	45.93	0.00e+00	875.00
IUUC-Itr-048460	Ictidomys tridecemlineatus	45.88	0.00e+00	891.00
IUUC-Kpa-049112	Komagataella pastoris	46.20	0.00e+00	846.00
IUUC-Lch-050371	Latimeria chalumnae	45.79	0.00e+00	882.00
IUUC-Loc-052936	Lepisosteus oculatus	46.98	0.00e+00	882.00
IUUC-Lma-053315	Leptosphaeria maculans	45.73	0.00e+00	867.00
IUUC-Laf-053948	Loxodonta africana	46.71	0.00e+00	872.00
IUUC-Mcc-055843	Macaca mulatta	46.03	0.00e+00	893.00
IUUC-Meu-056258	Macropus eugenii	45.88	0.00e+00	879.00
IUUC-Mor-057269	Magnaporthe oryzae	45.00	0.00e+00	843.00
IUUC-Mpo-057435	Magnaporthe poae	45.60	0.00e+00	840.00
IUUC-Mtr-058572	Medicago truncatula	80.30	0.00e+00	1662.00
IUUC-Mla-059176	Melampsora laricipopulina	46.50	0.00e+00	863.00
IUUC-Mga-059721	Meleagris gallopavo	39.78	0.00e+00	656.00
IUUC-Mvi-060437	Microbotryum violaceum	43.36	0.00e+00	808.00
IUUC-Mmr-061405	Microcebus murinus	44.97	0.00e+00	850.00
IUUC-Mdo-062032	Monodelphis domestica	44.67	0.00e+00	857.00
IUUC-Mmu-063280	Mus musculus	45.25	0.00e+00	868.00
IUUC-Mac-065505	Musa acuminata	81.76	0.00e+00	1718.00
IUUC-Mpu-066409	Mustela putorius furo	45.93	0.00e+00	895.00
IUUC-Mlu-067217	Myotis lucifugus	45.88	0.00e+00	880.00
IUUC-Nfi-068407	Neosartorya fischeri	46.31	0.00e+00	827.00
IUUC-Ncr-068698	Neurospora crassa	45.77	0.00e+00	847.00
IUUC-Nle-070072	Nomascus leucogenys	43.23	0.00e+00	798.00
IUUC-Opr-070715	Ochotona princeps	35.75	1.00e-155	542.00
IUUC-Ont-071671	Oreochromis niloticus	45.81	0.00e+00	869.00
IUUC-Ocu-074544	Oryctolagus cuniculus	45.88	0.00e+00	894.00
IUUC-Oba-075120	Oryza barthii	90.09	0.00e+00	1848.00
IUUC-Obr-076557	Oryza brachyantha	90.82	0.00e+00	1874.00
IUUC-Ogl-077887	Oryza glaberrima	90.09	0.00e+00	1850.00
IUUC-Oin-079370	Oryza indica	87.54	0.00e+00	1832.00
IUUC-Ome-081942	Oryza meridionalis	90.38	0.00e+00	1855.00
IUUC-Oni-082365	Oryza nivara	90.38	0.00e+00	1854.00
IUUC-Opu-083301	Oryza punctata	90.45	0.00e+00	1858.00
IUUC-Osa-085949	Oryza sativa	90.09	0.00e+00	1885.00
IUUC-Ola-087002	Oryzias latipes	46.71	0.00e+00	879.00
IUUC-Olu-087687	Ostreococcus lucimarinus	58.88	0.00e+00	1128.00
IUUC-Oga-088594	Otolemur garnettii	46.45	0.00e+00	880.00
IUUC-Oar-090068	Ovis aries	45.89	0.00e+00	889.00
IUUC-Pan-092114	Papio anubis	46.12	0.00e+00	894.00
IUUC-Psi-093489	Pelodiscus sinensis	39.05	0.00e+00	680.00
IUUC-Pma-094214	Petromyzon marinus	45.83	2.00e-33	133.00
IUUC-Pno-095154	Phaeosphaeria nodorum	44.38	0.00e+00	832.00
IUUC-Ppa-095227	Physcomitrella patens	73.52	0.00e+00	1545.00
IUUC-Pfo-097184	Poecilia formosa	45.41	0.00e+00	862.00
IUUC-Pab-097861	Pongo abelii	46.03	0.00e+00	865.00
IUUC-Pop-098934	Populus trichocarpa	79.94	0.00e+00	1679.00
IUUC-Pca-100347	Procavia capensis	43.18	0.00e+00	705.00
IUUC-Ppe-102012	Prunus persica	79.49	0.00e+00	1702.00
IUUC-Pva-102584	Pteropus vampyrus	46.17	0.00e+00	918.00
IUUC-Pgr-103336	Puccinia graminis	45.77	0.00e+00	832.00
IUUC-Ptt-103939	Puccinia triticina	46.62	0.00e+00	836.00
IUUC-Pte-104200	Pyrenophora teres	45.44	0.00e+00	863.00
IUUC-Pyt-104441	Pyrenophora triticirepentis	44.84	0.00e+00	856.00
IUUC-Rno-105462	Rattus norvegicus	45.25	0.00e+00	869.00
IUUC-Sce-106245	Saccharomyces cerevisiae	45.56	0.00e+00	868.00
IUUC-Sha-107142	Sarcophilus harrisii	46.10	0.00e+00	882.00
IUUC-Sja-107841	Schizosaccharomyces japonicus	45.55	0.00e+00	847.00
IUUC-Spo-108034	Schizosaccharomyces pombe	44.20	0.00e+00	822.00
IUUC-Ssl-108497	Sclerotinia sclerotiorum	45.09	0.00e+00	808.00
IUUC-Smo-109211	Selaginella moellendorffii	69.96	0.00e+00	1524.00
IUUC-Sit-110281	Setaria italica	90.42	0.00e+00	1883.00
IUUC-Sly-111237	Solanum lycopersicum	80.00	0.00e+00	1634.00
IUUC-Stu-112001	Solanum tuberosum	80.20	0.00e+00	1640.00
IUUC-Sar-113737	Sorex araneus	45.83	0.00e+00	879.00
IUUC-Sbi-114089	Sorghum bicolor	91.07	0.00e+00	1896.00
IUUC-Sre-115148	Sporisorium reilianum	45.48	0.00e+00	811.00
IUUC-Ssc-115777	Sus scrofa	45.64	0.00e+00	881.00
IUUC-Tgu-116565	Taeniopygia guttata	39.58	0.00e+00	681.00
IUUC-Tru-118742	Takifugu rubripes	46.61	0.00e+00	830.00
IUUC-Tni-120401	Tetraodon nigroviridis	46.71	0.00e+00	836.00
IUUC-Tca-121436	Theobroma cacao	80.40	0.00e+00	1696.00
IUUC-Tre-122009	Trichoderma reesei	46.93	0.00e+00	818.00
IUUC-Tvi-122259	Trichoderma virens	47.31	0.00e+00	837.00
IUUC-Tae-125113	Triticum aestivum	97.42	0.00e+00	1945.00
IUUC-Tur-126189	Triticum urartu	98.13	0.00e+00	1936.00
IUUC-Tme-127055	Tuber melanosporum	44.55	0.00e+00	799.00
IUUC-Tbe-127587	Tupaia belangeri	41.27	1.00e-139	489.00
IUUC-Ttr-128331	Tursiops truncatus	45.64	0.00e+00	872.00
IUUC-Uma-129387	Ustilago maydis	45.34	0.00e+00	818.00
IUUC-Vda-129977	Verticillium dahliae	46.82	0.00e+00	820.00
IUUC-Vvi-130857	Vitis vinifera	81.84	0.00e+00	1721.00
IUUC-Xtr-132947	Xenopus tropicalis	38.03	0.00e+00	628.00
IUUC-Xma-133805	Xiphophorus maculatus	45.21	0.00e+00	840.00
IUUC-Yli-134547	Yarrowia lipolytica	44.95	0.00e+00	853.00
IUUC-Zma-135758	Zea mays	89.25	0.00e+00	1855.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence