iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pyt-104441

Ensembl Protein ID

EDU42041

UniProt Accession

B2WGD4; B2WGD4_PYRTR

Genbank Protein ID

EDU42041.1

Protein Name

Ubiquitin-activating enzyme E1

Genbank Nucleotide ID

DS231624

Gene Name

PTRG_08990

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PTRG_08990	EDU42041	EDU42041

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	6.40e-187	621.1	422	906

Active Site

Position(s)	Description	Evidence
605	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveah..e 94
           YD+Qi+++G+e+q+kl++ k +lvGag++GcE+lKn +++G+     g+itv+D+d++e+snlnrqFLfr+ dvgk K+++aa+a++ +npd +++++  +
   Q: 422  YDGQIAVLGQEYQKKLSNVKQFLVGAGAIGCEMLKNWAMMGLgtgpeGKITVTDNDQIEKSNLNRQFLFRPADVGKLKSDAAAKAVQVMNPDLSGKIVtlQ 522
           *********************************************************************************************98776226 PP
   S: 95   esiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtiewa.. 190
           +++ +++e+i+   F + +d+V +aldn+ear++v+r+c+  r+pl++sgtlG++G+++v+++ +te+ys+s+dpp+k++P+ctl+++pn +ehti wa  
   Q: 523  DKVGPETEHIFneeFWNSLDGVTNALDNVEARTYVDRRCVFFRKPLLDSGTLGTKGNTQVVLPFITESYSSSQDPPEKSFPMCTLRSFPNRIEHTIAWAre 623
           89****99999999*************************************************************************************** PP
   S: 191  ..........vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikqllksfecdivtkskspfwv....... 274
                     +++n +l + +     l++  s + +++++  ++ l++e++ +f+++i +a+++f+k +++ i qll +f++d  t s++pfw+       
   Q: 624  sfdslfvkgpEIVNLYLTQPDYLGASLKQ--SGNEKQTLETLRDFLVTEKPLSFDDCIVWARHQFEKNYNHAIAQLLYNFPKDSKTGSGQPFWSgpkrapd 722
           **********9999999777666666663..45555556666677999***************************************************** PP
   S: 275  ........................................sfcsnaealq.......vpekvekdeevvkasap............lylllralerfekkk 316
                                                            +       +p+ ++k ++  k+++p            l   +  l   ++  
   Q: 723  pskfdpsnpthftyveaaatlhaynygikpnasrehyvevL--------NdmivpdfQPDPTVKIQADEKEPDPnanqaggddsgsLDSIINQLPAPKSLA 815
           **********9999999999999999666666555544440........14554555556666666655555556666666667789999*********** PP
   S: 317  grkpgelsfekddds..avdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsg..kfeplknfflfdae 404
           g k + ++fekddd   ++d++taa+nlrae+++ie+ +d++++k iag+iipaiatt+a v Gl+++E++K+++g  + e++kn f+++a+
   Q: 816  GFKLEPVEFEKDDDTnhHIDFITAASNLRAENYKIEQ-ADRHKTKFIAGKIIPAIATTTALVTGLVNLELYKIIDGktDIEQYKNGFINLAL 906
           **************999********************.**************************************777888******9875 PP

Organism

Pyrenophora triticirepentis

Protein Sequence
(Fasta)

MQVDSPATAI EQLKEASGNN GEIDESLYSR QLYVLGHEAM KRMGSSNVLV AGLRGLGVEI 60
AKNIALAGVK SLTLYDPKPA ALADLSSQFF LTPADVGKPR ASATVPKVSE LNPYTPVQEY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCAGGTCG ACAGTCCTGC CACTGCTATC GAACAGCTCA AGGAGGCATC CGGCAACAAT 60
GGCGAAATCG ACGAGTCCCT CTACAGCCGA CAGCTGTATG TGCTGGGCCA CGAGGCCATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0004839--F:ubiquitin activating enzyme activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000456	Aegilops tauschii	44.76	0.00e+00	837.00
IUUC-Aml-001311	Ailuropoda melanoleuca	52.34	0.00e+00	1062.00
IUUC-Atr-002684	Amborella trichopoda	44.09	0.00e+00	860.00
IUUC-Apl-004158	Anas platyrhynchos	43.93	0.00e+00	702.00
IUUC-Aca-004620	Anolis carolinensis	52.88	0.00e+00	1063.00
IUUC-Aly-005515	Arabidopsis lyrata	46.21	0.00e+00	877.00
IUUC-Ath-006891	Arabidopsis thaliana	45.83	0.00e+00	877.00
IUUC-Ago-007873	Ashbya gossypii	58.65	0.00e+00	1171.00
IUUC-Acl-008181	Aspergillus clavatus	73.95	0.00e+00	1571.00
IUUC-Afl-008455	Aspergillus flavus	73.40	0.00e+00	1531.00
IUUC-Afu-009065	Aspergillus fumigatus	73.85	0.00e+00	1603.00
IUUC-Ani-009371	Aspergillus nidulans	72.86	0.00e+00	1506.00
IUUC-Ang-009737	Aspergillus niger	73.31	0.00e+00	1572.00
IUUC-Aor-010007	Aspergillus oryzae	73.40	0.00e+00	1531.00
IUUC-Ate-010466	Aspergillus terreus	73.62	0.00e+00	1609.00
IUUC-Ame-010933	Astyanax mexicanus	53.15	0.00e+00	997.00
IUUC-Bgr-012281	Blumeria graminis	66.96	0.00e+00	1428.00
IUUC-Bta-012767	Bos taurus	52.83	0.00e+00	1065.00
IUUC-Bci-013721	Botrytis cinerea	70.97	0.00e+00	1427.00
IUUC-Bdi-014009	Brachypodium distachyon	43.58	0.00e+00	831.00
IUUC-Bol-015665	Brassica oleracea	46.40	0.00e+00	874.00
IUUC-Bra-017685	Brassica rapa	45.60	0.00e+00	883.00
IUUC-Cel-018260	Caenorhabditis elegans	45.56	0.00e+00	823.00
IUUC-Cja-019152	Callithrix jacchus	52.39	0.00e+00	1053.00
IUUC-Cfa-020622	Canis familiaris	51.29	0.00e+00	999.00
IUUC-Cpo-022526	Cavia porcellus	52.82	0.00e+00	1046.00
IUUC-Cre-022702	Chlamydomonas reinhardtii	43.50	0.00e+00	776.00
IUUC-Csa-023780	Chlorocebus sabaeus	52.63	0.00e+00	1053.00
IUUC-Cho-024682	Choloepus hoffmanni	41.89	1.00e-99	355.00
IUUC-Cin-025790	Ciona intestinalis	51.05	0.00e+00	1046.00
IUUC-Csv-026084	Ciona savignyi	50.14	0.00e+00	1035.00
IUUC-Cgl-026512	Colletotrichum gloeosporioides	68.62	0.00e+00	1476.00
IUUC-Cne-026960	Cryptococcus neoformans	58.70	0.00e+00	1172.00
IUUC-Cme-027290	Cyanidioschyzon merolae	41.22	0.00e+00	779.00
IUUC-Dre-028149	Danio rerio	53.44	0.00e+00	1039.00
IUUC-Dno-028884	Dasypus novemcinctus	52.54	0.00e+00	1060.00
IUUC-Dor-030229	Dipodomys ordii	49.86	0.00e+00	993.00
IUUC-Dse-031524	Dothistroma septosporum	75.55	0.00e+00	1583.00
IUUC-Dme-032045	Drosophila melanogaster	50.73	0.00e+00	1006.00
IUUC-Ete-033124	Echinops telfairi	42.84	5.00e-151	526.00
IUUC-Eca-033330	Equus caballus	52.44	0.00e+00	1055.00
IUUC-Eeu-035323	Erinaceus europaeus	43.52	5.00e-157	546.00
IUUC-Fca-036255	Felis catus	52.73	0.00e+00	1050.00
IUUC-Fal-036848	Ficedula albicollis	43.98	0.00e+00	720.00
IUUC-Fox-038007	Fusarium oxysporum	68.17	0.00e+00	776.00
IUUC-Fso-038339	Fusarium solani	69.50	0.00e+00	1428.00
IUUC-Gmo-039338	Gadus morhua	51.34	0.00e+00	1000.00
IUUC-Ggr-039823	Gaeumannomyces graminis	69.04	0.00e+00	1507.00
IUUC-Gga-040747	Gallus gallus	44.21	0.00e+00	706.00
IUUC-Gac-041773	Gasterosteus aculeatus	50.67	0.00e+00	996.00
IUUC-Gma-043198	Glycine max	45.09	0.00e+00	864.00
IUUC-Ggo-045336	Gorilla gorilla	52.63	0.00e+00	1042.00
IUUC-Hsa-045982	Homo sapiens	52.63	0.00e+00	1043.00
IUUC-Hvu-047418	Hordeum vulgare	44.42	0.00e+00	823.00
IUUC-Itr-048460	Ictidomys tridecemlineatus	52.44	0.00e+00	1053.00
IUUC-Kpa-049112	Komagataella pastoris	57.97	0.00e+00	1161.00
IUUC-Lch-050371	Latimeria chalumnae	52.58	0.00e+00	1044.00
IUUC-Lpe-051299	Leersia perrieri	42.42	0.00e+00	838.00
IUUC-Loc-052936	Lepisosteus oculatus	53.44	0.00e+00	1045.00
IUUC-Lma-053315	Leptosphaeria maculans	89.58	0.00e+00	1948.00
IUUC-Laf-053948	Loxodonta africana	54.58	0.00e+00	1039.00
IUUC-Mcc-055843	Macaca mulatta	52.73	0.00e+00	1058.00
IUUC-Meu-056258	Macropus eugenii	51.29	0.00e+00	1030.00
IUUC-Mor-057269	Magnaporthe oryzae	69.75	0.00e+00	1487.00
IUUC-Mpo-057435	Magnaporthe poae	68.71	0.00e+00	1469.00
IUUC-Mtr-058572	Medicago truncatula	46.18	0.00e+00	852.00
IUUC-Mla-059176	Melampsora laricipopulina	57.46	0.00e+00	1110.00
IUUC-Mga-059721	Meleagris gallopavo	43.65	0.00e+00	693.00
IUUC-Mvi-060437	Microbotryum violaceum	55.71	0.00e+00	1123.00
IUUC-Mmr-061405	Microcebus murinus	52.20	0.00e+00	1026.00
IUUC-Mdo-062032	Monodelphis domestica	49.81	0.00e+00	992.00
IUUC-Mmu-063280	Mus musculus	52.34	0.00e+00	1049.00
IUUC-Mac-065505	Musa acuminata	45.34	0.00e+00	857.00
IUUC-Mpu-066409	Mustela putorius furo	52.54	0.00e+00	1059.00
IUUC-Mlu-067217	Myotis lucifugus	52.06	0.00e+00	1047.00
IUUC-Nfi-068407	Neosartorya fischeri	74.33	0.00e+00	1588.00
IUUC-Ncr-068698	Neurospora crassa	70.39	0.00e+00	1499.00
IUUC-Nle-070072	Nomascus leucogenys	49.67	0.00e+00	952.00
IUUC-Opr-070715	Ochotona princeps	37.16	2.00e-172	598.00
IUUC-Ont-071671	Oreochromis niloticus	53.06	0.00e+00	1032.00
IUUC-Oan-073268	Ornithorhynchus anatinus	43.11	0.00e+00	664.00
IUUC-Ocu-074544	Oryctolagus cuniculus	52.63	0.00e+00	1061.00
IUUC-Oba-075120	Oryza barthii	46.93	0.00e+00	826.00
IUUC-Obr-076557	Oryza brachyantha	46.18	0.00e+00	817.00
IUUC-Ogl-077887	Oryza glaberrima	46.93	0.00e+00	828.00
IUUC-Ogu-078305	Oryza glumaepatula	43.31	0.00e+00	835.00
IUUC-Oin-080154	Oryza indica	43.21	0.00e+00	835.00
IUUC-Olo-081089	Oryza longistaminata	43.21	0.00e+00	838.00
IUUC-Ome-081942	Oryza meridionalis	47.14	0.00e+00	835.00
IUUC-Oni-082365	Oryza nivara	47.03	0.00e+00	833.00
IUUC-Opu-083301	Oryza punctata	46.68	0.00e+00	835.00
IUUC-Oru-084469	Oryza rufipogon	43.31	0.00e+00	837.00
IUUC-Osa-085949	Oryza sativa	46.83	0.00e+00	833.00
IUUC-Ola-087002	Oryzias latipes	53.25	0.00e+00	1040.00
IUUC-Olu-087687	Ostreococcus lucimarinus	42.31	0.00e+00	750.00
IUUC-Oga-088594	Otolemur garnettii	52.63	0.00e+00	1043.00
IUUC-Oar-090068	Ovis aries	52.54	0.00e+00	1065.00
IUUC-Ptr-090609	Pan troglodytes	43.44	0.00e+00	702.00
IUUC-Pan-092114	Papio anubis	52.73	0.00e+00	1058.00
IUUC-Psi-093489	Pelodiscus sinensis	44.46	0.00e+00	724.00
IUUC-Pma-094214	Petromyzon marinus	45.56	1.00e-39	154.00
IUUC-Pno-095154	Phaeosphaeria nodorum	89.22	0.00e+00	1943.00
IUUC-Ppa-095227	Physcomitrella patens	45.68	0.00e+00	851.00
IUUC-Pfo-097184	Poecilia formosa	52.68	0.00e+00	1035.00
IUUC-Pab-097861	Pongo abelii	52.44	0.00e+00	1028.00
IUUC-Pop-098934	Populus trichocarpa	45.56	0.00e+00	872.00
IUUC-Pca-100347	Procavia capensis	50.33	0.00e+00	877.00
IUUC-Ppe-102012	Prunus persica	45.28	0.00e+00	882.00
IUUC-Pva-102584	Pteropus vampyrus	52.92	0.00e+00	1090.00
IUUC-Pgr-103336	Puccinia graminis	55.36	0.00e+00	1051.00
IUUC-Ptt-103939	Puccinia triticina	54.37	0.00e+00	1046.00
IUUC-Pte-104200	Pyrenophora teres	97.90	0.00e+00	2107.00
IUUC-Rno-105462	Rattus norvegicus	52.06	0.00e+00	1040.00
IUUC-Sce-106245	Saccharomyces cerevisiae	60.15	0.00e+00	1246.00
IUUC-Sha-107142	Sarcophilus harrisii	51.20	0.00e+00	1038.00
IUUC-Sja-107841	Schizosaccharomyces japonicus	58.70	0.00e+00	1228.00
IUUC-Spo-108034	Schizosaccharomyces pombe	57.60	0.00e+00	1183.00
IUUC-Ssl-108497	Sclerotinia sclerotiorum	69.62	0.00e+00	1440.00
IUUC-Smo-109211	Selaginella moellendorffii	44.97	0.00e+00	843.00
IUUC-Sit-110281	Setaria italica	46.66	0.00e+00	853.00
IUUC-Sly-110914	Solanum lycopersicum	44.91	0.00e+00	884.00
IUUC-Stu-112109	Solanum tuberosum	44.82	0.00e+00	885.00
IUUC-Sar-113737	Sorex araneus	51.96	0.00e+00	1058.00
IUUC-Sbi-114520	Sorghum bicolor	47.22	0.00e+00	858.00
IUUC-Sre-115148	Sporisorium reilianum	55.06	0.00e+00	1101.00
IUUC-Ssc-115777	Sus scrofa	52.49	0.00e+00	1062.00
IUUC-Tgu-116565	Taeniopygia guttata	43.88	0.00e+00	715.00
IUUC-Tru-118742	Takifugu rubripes	52.87	0.00e+00	998.00
IUUC-Tsy-119436	Tarsius syrichta	38.91	8.00e-171	592.00
IUUC-Tni-120401	Tetraodon nigroviridis	52.68	0.00e+00	1000.00
IUUC-Tca-121672	Theobroma cacao	45.20	0.00e+00	880.00
IUUC-Tre-122009	Trichoderma reesei	68.85	0.00e+00	1399.00
IUUC-Tvi-122259	Trichoderma virens	68.70	0.00e+00	1392.00
IUUC-Tae-125676	Triticum aestivum	43.53	0.00e+00	844.00
IUUC-Tur-126330	Triticum urartu	44.76	0.00e+00	839.00
IUUC-Tme-127055	Tuber melanosporum	62.98	0.00e+00	1286.00
IUUC-Tbe-127587	Tupaia belangeri	43.21	2.00e-155	541.00
IUUC-Ttr-128331	Tursiops truncatus	52.54	0.00e+00	1051.00
IUUC-Uma-129387	Ustilago maydis	56.74	0.00e+00	1109.00
IUUC-Vda-129977	Verticillium dahliae	69.33	0.00e+00	1388.00
IUUC-Vpa-130716	Vicugna pacos	41.78	0.00e+00	678.00
IUUC-Vvi-130857	Vitis vinifera	45.02	0.00e+00	869.00
IUUC-Xtr-132947	Xenopus tropicalis	39.01	0.00e+00	646.00
IUUC-Xma-133805	Xiphophorus maculatus	52.77	0.00e+00	1022.00
IUUC-Yli-134547	Yarrowia lipolytica	58.65	0.00e+00	1199.00
IUUC-Zma-135052	Zea mays	46.37	0.00e+00	855.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence