iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000020666.3	ENSMMUT00000055844.1	ENSMMUP00000044630.1
ENSMMUG00000020666.3	ENSMMUT00000069297.1	ENSMMUP00000052687.1
ENSMMUG00000020666.3	ENSMMUT00000029068.3	ENSMMUP00000027196.3
ENSMMUG00000020666.3	ENSMMUT00000058323.1	ENSMMUP00000052422.1
ENSMMUG00000020666.3	ENSMMUT00000074415.1	ENSMMUP00000052824.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.20e-54	184.9	18	148
UBD/UBC-like/UBD_UBC	6.00e-83	276.9	18	151

Active Site

Position(s)	Description	Evidence
94	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 5    elkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWs 93
           el++l++dpp+++sa+pv + d+++w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPkv f+t+i+hPn+++nG++Cl+il+  ++Ws
   Q: 18   ELNDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR--SQWS 103
           899*****************.9************************************************************9..**** PP
   S: 94   palsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           pal++++vllsi+sll++pnp++pl  e+a+++k++re+y++++r
   Q: 104  PALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNRIAR 148
           *****************************************9987 PP

UBD/UBC-like/UBD_UBC

   S: 5    elkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqwsaal 93
           el+dl+rd++aq+sa++v+dd+f+++ati+gp+dspy+ggvfflti++ptdypfkppkvaf+t+iyhpninsngsicldilrsqws+al
   Q: 18   ELNDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPAL 106
           9**************************************************************************************** PP
   S: 94   tlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           t+skvlls+csll+d++pddplv+eiariyktd+eky+riarewt
   Q: 107  TISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNRIAREWT 151
           ********************************************8 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

RLRLKKKKKK EMESHSIELN DLARDPPAQC SAGPVGDDMF HWQATIMGPN DSPYQGGVFF 60
LTIHFPTDYP FKPPKVAFTT RIYHPNINSN GSICLDILRS QWSPALTISK VLLSICSLLC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGCCCAGGG CCTCGCAGCA TCACCCGCTC CGCCGCCGTG GCGGCGGCGG CGGCGGCGGC 60
GGCGGTGCGT AGCTTACTCA CAGGGGCGGC CCGTATCCCT CCGCCGCCGG CGCGGCTCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001778	Ailuropoda melanoleuca	100.00	1.00e-81	294.00
IUUC-Apl-003199	Anas platyrhynchos	100.00	1.00e-81	294.00
IUUC-Aca-005236	Anolis carolinensis	100.00	8.00e-82	295.00
IUUC-Bta-013158	Bos taurus	100.00	8.00e-82	295.00
IUUC-Cja-019886	Callithrix jacchus	100.00	8.00e-82	295.00
IUUC-Cfa-020436	Canis familiaris	100.00	8.00e-82	295.00
IUUC-Cpo-021714	Cavia porcellus	97.84	1.00e-79	288.00
IUUC-Dno-028952	Dasypus novemcinctus	100.00	9.00e-82	295.00
IUUC-Ete-032295	Echinops telfairi	100.00	1.00e-81	294.00
IUUC-Eca-033293	Equus caballus	97.22	9.00e-82	295.00
IUUC-Gga-040758	Gallus gallus	100.00	8.00e-82	295.00
IUUC-Ggo-045375	Gorilla gorilla	97.92	2.00e-82	297.00
IUUC-Hsa-045885	Homo sapiens	100.00	8.00e-82	295.00
IUUC-Itr-048882	Ictidomys tridecemlineatus	98.59	5.00e-82	296.00
IUUC-Lch-050583	Latimeria chalumnae	92.03	2.00e-73	267.00
IUUC-Loc-052788	Lepisosteus oculatus	98.56	7.00e-81	292.00
IUUC-Laf-053580	Loxodonta africana	100.00	1.00e-81	294.00
IUUC-Mmr-061474	Microcebus murinus	100.00	8.00e-82	295.00
IUUC-Mdo-062962	Monodelphis domestica	100.00	8.00e-82	295.00
IUUC-Mmu-063518	Mus musculus	100.00	8.00e-82	295.00
IUUC-Mpu-066604	Mustela putorius furo	99.29	8.00e-82	295.00
IUUC-Nle-069800	Nomascus leucogenys	98.56	2.00e-78	284.00
IUUC-Ont-071766	Oreochromis niloticus	98.56	8.00e-81	291.00
IUUC-Ocu-074315	Oryctolagus cuniculus	100.00	8.00e-82	295.00
IUUC-Ola-086331	Oryzias latipes	98.56	8.00e-81	291.00
IUUC-Ptr-090707	Pan troglodytes	100.00	8.00e-82	295.00
IUUC-Pan-092143	Papio anubis	100.00	8.00e-82	295.00
IUUC-Pfo-096753	Poecilia formosa	98.56	8.00e-81	291.00
IUUC-Pab-097764	Pongo abelii	100.00	8.00e-82	295.00
IUUC-Ptt-103723	Puccinia triticina	76.92	6.00e-62	229.00
IUUC-Sar-113302	Sorex araneus	100.00	1.00e-81	294.00
IUUC-Tru-118272	Takifugu rubripes	98.56	2.00e-80	290.00
IUUC-Tsy-119491	Tarsius syrichta	97.12	1.00e-76	279.00
IUUC-Tni-120056	Tetraodon nigroviridis	98.56	2.00e-80	290.00
IUUC-Tbe-127609	Tupaia belangeri	100.00	5.00e-68	248.00
IUUC-Vpa-130446	Vicugna pacos	96.53	3.00e-80	291.00
IUUC-Xtr-132329	Xenopus tropicalis	100.00	8.00e-82	295.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence