iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSG00000132716.18	ENST00000477163.1	ENSP00000477386.1
ENSG00000132716.18	ENST00000473382.2	ENSP00000476539.1
ENSG00000132716.18	ENST00000461888.5	ENSP00000476407.1
ENSG00000132716.18	ENST00000490368.5	ENSP00000477255.1
ENSG00000132716.18	ENST00000610139.5	ENSP00000477464.1

Annotation

Cancer Mutation
TCGA	ICGC	COSMIC	CGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	TCGA	ICGC
COSMIC	THPA	HPM
DNA & RNA Element
circBase	circRNADb	CircNet	miRTarBase
microRNA	TRANSFAC	SomamiR	miRcode
RAID2
Protein-protein Interaction
HINT	InWeb_IM
Disease-associated Variation
ClinVar	GWASdb	OMIM
Post-translational Modifications (PTMs)
BioGRID	mUbiSiDa
DNA Methylation
TCGA	ICGC	COSMIC
Protein Expression/Proteomics
THPA	HPM	GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.80e-15	55.9	191	222

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDl 30
           gHt+ v+ l+f   +t l+sGsdD ++ vWD+
   Q: 191  GHTGCVNTLHFnqRGTWLASGSDDLKVVVWDW 222
           8**********86559***************7 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

MSSKGSSTDG RTDLANGSLS SSPEEMSGAE EGRETSSGIE VEASDLSLSL TGDDGGPNRT 60
STESRGTDTE SSGEDKDSDS MEDTGHYSIN DENRVHDRSE EEEEEEEEEE EEQPRRRVQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCGCAAACG GGGCCGGAAA GCGTGGCAGC GCAGGCGCAA GCGCAGAGAG CGGAGGCGGT 60
GGTGGTGGCG GCCGCTGGCC AGTGTAAGAT GGCGGCGGCG TTGGTGGTGG CAGTGGACGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID

Species

Identity

E-value

Score

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence