iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-022049

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02053326

Gene Name

USP26

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000007444.3	ENSCPOT00000007516.2	ENSCPOP00000006715.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	6.70e-75	252.3	281	854

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +Gl NlgNtCY+N+vLQ+L +ip + +++l+   +++++    ++  +l+++l   ++ + + + k     +++k+l+ +ae fs  +q
   Q: 281  QGLPNLGNTCYINAVLQSLCSIPLFVNDVLN---QRFPWARICHDIFCLCMALLLTMKDVFNMSIKEKLLVTIKKTLSLVAEIFSMDAQ 366
           6******************************...******9999999**************99999999999***************** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +Da+Efl+f+ldq+++ +++   +++   +e ++  ++  + ++ +  + ++++++F+ +l  +i c++c++   ++ep+++ls+++p+
   Q: 367  NDAHEFLSFCLDQMKDGFEM---SSIFGRSEYQSLPQQAFSGDSATGMTGCPVVTNFECELLRSIFCKACGQAVYKTEPNNYLSINLPQ 452
           ******************55...344444455666777889999999999*************************************** PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
            ++t+ +s+q+ L++f+++eele    y+c +ck+k+ +    k++klP++Li+hLkR++f+e   s +k ++ v++p  Ldls++c++
   Q: 453  GKKTQSLSIQSTLDHFFATEELE----YKCAECKHKR-SDIVYKFSKLPRILIIHLKRYRFTEV-LSLRKDDQAVTIPTYLDLSSHCNE 535
           **********************9....*******999.68899******************998.6667******************** PP
   S: 268  ......................................................................................... 267
                                                                                                    
   Q: 536  stklpvplsrtahirnmrlllafqklsfsilcslsllkseapknsrpkrdksgkgsdsqkpqrflkgktvqqqkvgkreadsaclesav 624
           999*******9999999999999999999999999999999999999999999999999999999998888888888888888888888 PP
   S: 268  ......................................................................................... 267
                                                                                                    
   Q: 625  mpreqqladslmnledpylplfsrysgtpfsssdtcltetqvqampenrkvkksgktntfaesdfvsvsettgdfskdkktrvtgksrk 713
           88888888888888888888888888888888888888888888877777777777777777777777777777766666666666666 PP
   S: 268  ............................peekqke..............................................kkkYeLia 282
                                       p     +                                              +++Y+Li+
   Q: 714  vtkqnkgydergihkdtpqhtlpegipkP-----DaqkhqvnvrgqtelnlqkakpgnkdssrkktkskisepeekvdninPHTYRLIG 797
           66666666555555555555555555550.....05555556666666666666666666666677777788888888899******** PP
   S: 283  vvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYkr 337
           +++H G +l+sGHY++++++ +++ W +++D  V++++e++v++++ s++Y++fY++
   Q: 798  IISHLGsTLNSGHYITDAYDFTKQaWSTYNDLLVSSISESQVKKDRVSSGYIFFYMH 854
           ********************99889********************99********98 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MSSIMVPGYA QIWSKRSGMS KTQNVFLEAV KGRKNFKLLI YFKTGKVKTF HLNNNIRSAS 60
FTSYGEDFTH LHLVFRNNGF LIVERLASTD AEQLKVFLAS VPQDNSEPRM NPDEEDNESV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGTAGCA TAATGGTACC TGGTTATGCC CAAATATGGA GCAAGAGGTC AGGAATGTCG 60
AAGACACAAA ATGTATTCTT AGAAGCAGTG AAAGGAAGGA AGAATTTTAA ACTGCTGATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR032069--USP37-like_PH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH
PF16674--UCH_N

Gene Ontology

GO:0005634--C:nucleus
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002281	Ailuropoda melanoleuca	40.76	2.00e-173	602.00
IUUC-Bta-012832	Bos taurus	37.97	8.00e-152	531.00
IUUC-Cel-018389	Caenorhabditis elegans	34.33	3.00e-07	50.80
IUUC-Cja-019801	Callithrix jacchus	39.59	2.00e-161	563.00
IUUC-Cfa-020088	Canis familiaris	42.47	0.00e+00	645.00
IUUC-Csa-023990	Chlorocebus sabaeus	42.59	4.00e-175	608.00
IUUC-Dor-030370	Dipodomys ordii	38.23	9.00e-153	534.00
IUUC-Ete-032723	Echinops telfairi	33.87	3.00e-78	286.00
IUUC-Eca-034060	Equus caballus	42.83	4.00e-176	612.00
IUUC-Fca-035628	Felis catus	41.14	7.00e-171	594.00
IUUC-Ggo-045311	Gorilla gorilla	40.98	1.00e-169	590.00
IUUC-Hsa-046292	Homo sapiens	41.22	1.00e-168	587.00
IUUC-Itr-047983	Ictidomys tridecemlineatus	46.67	0.00e+00	724.00
IUUC-Laf-054311	Loxodonta africana	38.53	3.00e-145	509.00
IUUC-Mmr-061542	Microcebus murinus	43.96	0.00e+00	689.00
IUUC-Mmu-063365	Mus musculus	39.75	2.00e-117	416.00
IUUC-Mpu-066846	Mustela putorius furo	41.23	3.00e-173	602.00
IUUC-Mlu-068224	Myotis lucifugus	41.65	3.00e-167	582.00
IUUC-Nle-069425	Nomascus leucogenys	39.57	1.00e-158	553.00
IUUC-Ocu-073860	Oryctolagus cuniculus	42.54	4.00e-170	592.00
IUUC-Oar-089263	Ovis aries	38.04	8.00e-155	541.00
IUUC-Pan-092928	Papio anubis	41.80	2.00e-169	589.00
IUUC-Pab-098555	Pongo abelii	41.57	1.00e-177	617.00
IUUC-Rno-105919	Rattus norvegicus	39.20	1.00e-115	410.00
IUUC-Sar-113624	Sorex araneus	41.53	2.00e-113	403.00
IUUC-Ssc-116225	Sus scrofa	42.25	0.00e+00	640.00
IUUC-Tbe-127615	Tupaia belangeri	43.64	1.00e-90	327.00
IUUC-Ttr-129071	Tursiops truncatus	39.56	2.00e-154	540.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence