iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-047983

Ensembl Protein ID

ENSSTOP00000018576.1

UniProt Accession

I3N2I0; I3N2I0_ICTTR

Genbank Protein ID

ENSSTOP00000018576

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01094845

Gene Name

USP26

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000021496.1	ENSSTOT00000029167.1	ENSSTOP00000018576.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.50e-77	259.9	297	894

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +Gl NlgNtCYmN+vLQ+L +ip++ ++ll+   + +++ + +++  +l+ +   +++ +++  +k+    +++ka++ +a  fsg  q
   Q: 297  QGLPNLGNTCYMNAVLQSLCSIPSFVNDLLN---QGFPWGKIPHDALSLCLAQLLVLKDIYNIATKVKLLVSIKKAISLVADIFSGDVQ 382
           6******************************...*****9765665566655556678888999999999******************* PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +Da+Efl+ +ldq++e++++ +   k+++e e++s  +    ++++k   +++ ++F++++  +i c++c++   ++ep+++ls+++p+
   Q: 383  NDAHEFLSLCLDQMKETMQRLSLMWKTKMELEEDSPEKLLFAYSPTKMIVCPVITNFEFEILRSIFCKSCGRAVLKTEPNNYLSINLPQ 471
           ******************884444444444555556666699*********************************************** PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
            ++ +++s+q+ ++ f+ +eele    y+ce+c++++      k+++lP+vLi+hLkR++ +e+ +s +k +++v +p  L+ls++c++
   Q: 472  GTKADPLSIQSTFDLFFDAEELE----YKCEQCNHYRS-IAVQKFSRLPRVLIVHLKRYRLNEY-WSLRKDEQEVIIPTYLKLSSHCNE 554
           **********************9....*******9995.6666****************99887.************************ PP
   S: 268  ......................................................................................... 267
                                                                                                    
   Q: 555  ntkpplplsenahikdfhllkifqnmsfgilnltmpetkltskskdslplhigsnkksvpqkfqrflkgagreqqqkdleknsklnimk 643
           99999999999999999999999999999999999999999999999999999999999999999999999888888888888888888 PP
   S: 268  ......................................................................................... 267
                                                                                                    
   Q: 644  selassgnvtltgqqlsagsmnyvkdtslspickdggkpspdtslaeahsqevsenteikkheeingfveldfssfsettedlyedknp 732
           88888888888888888888888877777777777777777777777777777777766666666666666666666666666666666 PP
   S: 268  .......................................peekqke........................................... 274
                                                  +     e                                           
   Q: 733  sipgifqnvarqtqqcdsvrihkqaleqalpqslpklnaQ-----Ehtqnfrptelnvqkpdvnslcsvdanrnpedkdildkteskak 816
           6666666666666666666666666655555555555550.....05555555555555555555666666666666666666666666 PP
   S: 275  .............kkkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYkr 337
                        +++Y+Li+v++H G +++sGHY++++++ k++ W++++D ++++++e +v++++ +t+Y++fY++
   Q: 817  epkepkrsadkrdRHTYRLIGVISHIGsTTHSGHYITDAYDFKRHlWFTYNDLQISSIQEVQVQKSRLCTGYIFFYMH 894
           7777777778888****************************99999*******************999********97 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MSSATTVHGY VQIWNMKTGM SKSTAAFIEP VEGKKKVKLM LYFNTGQVKT FQLSDNIKSV 60
AFRAYGQNEN HLHLTFQNND FLFVERLSST HARELKTLLD RVHQIGGQPP MKPGKEDGVF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCATCTG CCACAACGGT ACACGGTTAT GTCCAAATAT GGAACATGAA GACAGGGATG 60
TCTAAATCAA CAGCAGCATT CATTGAACCA GTGGAAGGAA AGAAGAAAGT TAAACTGATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR032069--USP37-like_PH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH
PF16674--UCH_N

Gene Ontology

GO:0005634--C:nucleus
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002281	Ailuropoda melanoleuca	54.07	0.00e+00	905.00
IUUC-Bta-012832	Bos taurus	45.19	0.00e+00	694.00
IUUC-Cja-019801	Callithrix jacchus	49.67	0.00e+00	781.00
IUUC-Cfa-020088	Canis familiaris	54.59	0.00e+00	924.00
IUUC-Cpo-022049	Cavia porcellus	45.89	0.00e+00	719.00
IUUC-Csa-023990	Chlorocebus sabaeus	55.33	0.00e+00	908.00
IUUC-Dno-028968	Dasypus novemcinctus	47.29	0.00e+00	724.00
IUUC-Dor-030370	Dipodomys ordii	46.64	0.00e+00	736.00
IUUC-Ete-032723	Echinops telfairi	37.76	6.00e-89	321.00
IUUC-Eca-034060	Equus caballus	55.84	0.00e+00	900.00
IUUC-Fca-035628	Felis catus	52.44	0.00e+00	868.00
IUUC-Ggo-045311	Gorilla gorilla	55.11	0.00e+00	901.00
IUUC-Hsa-046292	Homo sapiens	54.42	0.00e+00	886.00
IUUC-Laf-054311	Loxodonta africana	47.78	0.00e+00	728.00
IUUC-Mcc-055452	Macaca mulatta	45.46	0.00e+00	723.00
IUUC-Mmr-061542	Microcebus murinus	57.84	0.00e+00	996.00
IUUC-Mmu-063365	Mus musculus	44.60	8.00e-148	517.00
IUUC-Mpu-066846	Mustela putorius furo	52.28	0.00e+00	885.00
IUUC-Mlu-068224	Myotis lucifugus	53.76	0.00e+00	845.00
IUUC-Nle-069425	Nomascus leucogenys	44.61	0.00e+00	718.00
IUUC-Ocu-073860	Oryctolagus cuniculus	51.52	0.00e+00	832.00
IUUC-Oga-088020	Otolemur garnettii	46.23	0.00e+00	713.00
IUUC-Oar-089263	Ovis aries	45.59	0.00e+00	724.00
IUUC-Pan-092928	Papio anubis	54.14	0.00e+00	874.00
IUUC-Ppa-095732	Physcomitrella patens	28.62	2.00e-24	107.00
IUUC-Pab-098555	Pongo abelii	55.24	0.00e+00	930.00
IUUC-Pca-100925	Procavia capensis	43.77	0.00e+00	679.00
IUUC-Rno-105919	Rattus norvegicus	41.13	2.00e-178	619.00
IUUC-Sar-113624	Sorex araneus	46.35	3.00e-137	482.00
IUUC-Ssc-116225	Sus scrofa	55.41	0.00e+00	957.00
IUUC-Tsy-119113	Tarsius syrichta	44.09	0.00e+00	640.00
IUUC-Tbe-127615	Tupaia belangeri	57.11	8.00e-131	461.00
IUUC-Ttr-129071	Tursiops truncatus	48.49	0.00e+00	800.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence