iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066846

Ensembl Protein ID

ENSMPUP00000018946.1

UniProt Accession

M3Z5T4; M3Z5T4_MUSPF

Genbank Protein ID

ENSMPUP00000018946

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01100512

Gene Name

USP26

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000019069.1	ENSMPUT00000019221.1	ENSMPUP00000018946.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.20e-78	264.6	317	915

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgy 87
           +Gl NlgNtCYmN+vLQ+L++ip+++++ll+   ++++++  k p g+l+++l++lf      + k k     +++ka++++ae fsg+
   Q: 317  QGLPNLGNTCYMNAVLQSLFSIPSFADDLLS---QDFPWD--KIPLGALSMCLAQLFVLKNiyNIKIKERLLVNIKKAISTVAEIFSGN 400
           6******************************...*****9..68************965545599999999999*************** PP
   S: 88   eqqDaqEflaflldqleeelkk.eknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslp 175
            q+Da+Efl ++ldq++e++ k ++ ++ + e++ed+++++  a++  ++   +++ ++F+++l  +i+c++c++v  ++e  ++ls++
   Q: 401  IQNDAHEFLGHCLDQMKENMGKlNTIWKMKIESKEDNTAQQVFADSAATRVLICPVITNFEFELLRSIICQACGQVVLKTEVSNYLSIN 489
           ********************775777777778888888999999999999999************************************ PP
   S: 176  vpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspf 264
           +p+  +  ++s+q++++ f+ +eele    y+cekc++++ ++  +k+++lP+vLi+hLkR+ f+e  +s +k +++v + + L+ls++
   Q: 490  LPQGMKALPLSIQSAFDLFFGAEELE----YKCEKCQHRS-SVAVHKFSRLPRVLIVHLKRYIFNEF-WSLRKDDQEVVISKYLKLSSH 572
           *************************9....******9776.89*********************997.********************* PP
   S: 265  cts...................................................................................... 267
           c++                                                                                      
   Q: 573  CNEstkpplpvsknvhnrdiqvlkvfqklsaerlqpsalsqkltsasrvhrvphagsdkeskpqksrilyegsrreqqkkdlgkrsrln 661
           ***99999999999999999999999999999999999999999999999999999999988888888888888888888888888888 PP
   S: 268  ......................................................................................... 267
                                                                                                    
   Q: 662  gtdsklvnlgdgiviekevlaaglmidleqvspylicdnegkprsgpethlagihlqeasenrkrkkykktntlvdfesvadtvedfyd 750
           88888888888888888888888888888888888888777777777777777777777777776666666666666666666666666 PP
   S: 268  ..............peekqke.................................................................... 274
                         +     +                                                                    
   Q: 751  gkknriskesqklaE-----Qtkqqervrlyeqalqqallqallkphvqwytqnlrrhtdlslqganvnslgesssnkspgkkqalhtk 834
           666666655555551.....055555666666666666666666666666666677777777777777777777777777778888888 PP
   S: 275  ................kkkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYkr 337
                            + Y+Li+vv+H G s++sGHY++++++ +++ W++++D +V++++e+ ++e + +t+Y++fY++
   Q: 835  teteaktpkgsaemrdLYAYRLIGVVSHLGkSPNSGHYISDAYDFERQvWFTYNDLQVSSIQEALMQEARLCTGYIFFYMH 915
           8888889999999999****************************99999*******************999********98 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MATLRVHGFV QIWNRKMGMS RTKEAYIETV ERKKRIKLVV CFTTGESVTF QLNNIKNVVF 60
RSYGEKQNHL RLIFQNNSFL FMERLYFRDA VQLKMFLDRV HQNNTQSSVR PGKDGDIFAR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCACTC TAAGGGTACA TGGTTTTGTC CAAATATGGA ACAGGAAGAT GGGGATGTCT 60
AGGACCAAAG AAGCATACAT TGAAACAGTA GAAAGAAAGA AGAGGATCAA ATTGGTGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR032069--USP37-like_PH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH
PF16674--UCH_N

Gene Ontology

GO:0005634--C:nucleus
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002281	Ailuropoda melanoleuca	78.71	0.00e+00	1399.00
IUUC-Bta-012832	Bos taurus	52.10	0.00e+00	851.00
IUUC-Cja-019801	Callithrix jacchus	49.58	0.00e+00	823.00
IUUC-Cfa-020088	Canis familiaris	75.18	0.00e+00	1366.00
IUUC-Cpo-022049	Cavia porcellus	39.62	2.00e-173	603.00
IUUC-Csa-023990	Chlorocebus sabaeus	55.44	0.00e+00	918.00
IUUC-Dno-028968	Dasypus novemcinctus	48.77	0.00e+00	795.00
IUUC-Dor-030370	Dipodomys ordii	41.73	0.00e+00	635.00
IUUC-Ete-033046	Echinops telfairi	50.00	4.00e-90	325.00
IUUC-Eca-034060	Equus caballus	63.06	0.00e+00	1106.00
IUUC-Fca-035628	Felis catus	65.29	0.00e+00	1152.00
IUUC-Ggo-045311	Gorilla gorilla	55.08	0.00e+00	919.00
IUUC-Hsa-046292	Homo sapiens	54.77	0.00e+00	905.00
IUUC-Itr-047983	Ictidomys tridecemlineatus	52.28	0.00e+00	877.00
IUUC-Laf-054311	Loxodonta africana	48.73	0.00e+00	770.00
IUUC-Mcc-055452	Macaca mulatta	47.55	0.00e+00	790.00
IUUC-Mmr-061542	Microcebus murinus	60.49	0.00e+00	1055.00
IUUC-Mlu-068224	Myotis lucifugus	59.75	0.00e+00	1006.00
IUUC-Nle-069425	Nomascus leucogenys	46.15	0.00e+00	765.00
IUUC-Opr-070989	Ochotona princeps	33.47	2.00e-90	327.00
IUUC-Ocu-073860	Oryctolagus cuniculus	51.16	0.00e+00	846.00
IUUC-Oga-088020	Otolemur garnettii	47.93	0.00e+00	781.00
IUUC-Oar-089263	Ovis aries	52.76	0.00e+00	892.00
IUUC-Pan-092928	Papio anubis	54.70	0.00e+00	892.00
IUUC-Pab-098555	Pongo abelii	55.43	0.00e+00	942.00
IUUC-Pca-100925	Procavia capensis	44.17	0.00e+00	684.00
IUUC-Sar-113624	Sorex araneus	45.47	0.00e+00	663.00
IUUC-Ssc-116225	Sus scrofa	63.73	0.00e+00	1137.00
IUUC-Tsy-119113	Tarsius syrichta	46.73	0.00e+00	741.00
IUUC-Tbe-127615	Tupaia belangeri	57.65	9.00e-132	464.00
IUUC-Ttr-129071	Tursiops truncatus	53.61	0.00e+00	923.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence