iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-073860

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02046755

Gene Name

USP26

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000025094.1	ENSOCUT00000029535.1	ENSOCUP00000016932.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.30e-79	265.4	285	879

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgy 87
           +Gl NlgNtCYmN+vLQ+L++ip+++++ll+   +++++     p   l+++l++l+      + k k     ++++a++++ae fsg 
   Q: 285  QGLPNLGNTCYMNAVLQTLFSIPSFADDLLN---QRFPWG--GIPVDGLSTCLAQLLILKGiyNVKVKEKLLVNVKNAISAVAEIFSGD 368
           6******************************...9****9..67888888888888754434488888889999*************** PP
   S: 88   eqqDaqEflaflldqleeelkk.eknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslp 175
            q+Da+Efl ++l+q++e++ + ++ +  ++e+ee++s++++ a+++  k   +++ ++F+ +l  +i+c+ c++   + ep ++ls++
   Q: 369  TQNDAHEFLGHCLQQVKENVVNlNTMWMNKNESEEENSSQDEFASSSASKMPACPVITNFELELLCSIICKGCGQFVIKMEPSNYLSIN 457
           ********************443555555555566666666778889999999************************************ PP
   S: 176  vpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspf 264
           +p+ +++ + s+q+ L++f+++eele    y+c kc++k+ ++  +k+++lP+vLi+hLkR+sf+ + +s +k +++v + + L+ls +
   Q: 458  LPQGKKMFPVSIQSTLNNFFSAEELE----YKCGKCQHKR-SVAFHKFNRLPRVLIIHLKRYSFNDY-WSIRKDDQEVIISKYLKLSAH 540
           *************************9....*******999.89*********************997.********************9 PP
   S: 265  cts...................................................................................... 267
           c+                                                                                       
   Q: 541  CNLntkppfplsknthprelqilkifqtvnsgiissppsknsasdlkksldlpvasydesnkfqrifkgskkgkkqndlgkdsklntve 629
           999999*****999999999999999999999999999999999999999999999999999999999998888888888888888888 PP
   S: 268  ......................................................................................... 267
                                                                                                    
   Q: 630  aefvnpgdktlrekqplagsvrhlgdtslslnrkgrgkhttnpytrleallqkltenrklqvygktsvpveldsdgvtktkdsyenkkh 718
           88888888888888888888888888888888888888888888888888877777777777777777777777777777777777666 PP
   S: 268  .....................................peekqke............................................. 274
                                                +                                                   
   Q: 719  tiqegspkvanhiqkcagvriykqasqqvppqslpksK-----Aqkqaenltrstefsfqavsanhvsalgsntnpgnkgifgekkmds 802
           66666666666666666666666666666666665550.....0455556666666666666666666666666666666777777777 PP
   S: 275  ............kkkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYkr 337
                       +++Y+Li+vv+H G s++sGHY++++++ +++ W++++D +V++++e+ +l+++++t+Yv+fY++
   Q: 803  kaqepkintdkaNHTYRLIGVVSHLGsSPDSGHYISDAYDFERQaWFTYNDLHVQSIQEAPMLNSRACTGYVFFYMH 879
           777777777777****************************99999******************************98 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MDAVMVHGFV QMWEKNSGMS KSKEAFIETV PGRKKDKLVI YFNAEKMRTF QLTDNIKSVV 60
LRSREDDQNH LHLTFQNNNF LFIERLSSSD AQELKLYLDR VHQKKLEPSM RAHKDKPISI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATGCCG TGATGGTACA TGGTTTTGTC CAAATGTGGG AGAAGAACAG TGGGATGTCA 60
AAGTCAAAAG AAGCATTCAT TGAAACAGTG CCAGGAAGGA AGAAAGATAA ACTAGTGATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR032069--USP37-like_PH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH
PF16674--UCH_N

Gene Ontology

GO:0005634--C:nucleus
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ocu:100344862

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002281	Ailuropoda melanoleuca	53.89	0.00e+00	892.00
IUUC-Bta-012832	Bos taurus	46.09	0.00e+00	698.00
IUUC-Cja-019801	Callithrix jacchus	47.20	0.00e+00	763.00
IUUC-Cfa-020088	Canis familiaris	53.77	0.00e+00	913.00
IUUC-Cpo-022049	Cavia porcellus	41.35	8.00e-174	603.00
IUUC-Csa-023990	Chlorocebus sabaeus	52.12	0.00e+00	843.00
IUUC-Dor-030370	Dipodomys ordii	44.04	0.00e+00	676.00
IUUC-Eca-034060	Equus caballus	53.26	0.00e+00	869.00
IUUC-Fca-035628	Felis catus	51.08	0.00e+00	841.00
IUUC-Ggo-045311	Gorilla gorilla	52.00	0.00e+00	845.00
IUUC-Hsa-046292	Homo sapiens	51.74	0.00e+00	838.00
IUUC-Itr-047983	Ictidomys tridecemlineatus	51.52	0.00e+00	847.00
IUUC-Laf-054311	Loxodonta africana	47.89	0.00e+00	735.00
IUUC-Mmr-061542	Microcebus murinus	56.54	0.00e+00	953.00
IUUC-Mmu-063365	Mus musculus	43.42	2.00e-136	479.00
IUUC-Mpu-066846	Mustela putorius furo	51.27	0.00e+00	880.00
IUUC-Mlu-068224	Myotis lucifugus	51.08	0.00e+00	818.00
IUUC-Oga-088020	Otolemur garnettii	45.05	0.00e+00	727.00
IUUC-Oar-089263	Ovis aries	46.15	0.00e+00	706.00
IUUC-Pan-092928	Papio anubis	52.12	0.00e+00	832.00
IUUC-Pab-098555	Pongo abelii	52.11	0.00e+00	883.00
IUUC-Pca-100925	Procavia capensis	42.48	2.00e-179	622.00
IUUC-Sar-113624	Sorex araneus	41.35	5.00e-159	555.00
IUUC-Ssc-116225	Sus scrofa	53.09	0.00e+00	890.00
IUUC-Tbe-127615	Tupaia belangeri	53.01	3.00e-123	436.00
IUUC-Ttr-129071	Tursiops truncatus	46.32	0.00e+00	741.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence