iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000013433.1	ENSONIT00000016904.1	ENSONIP00000016889.1
ENSONIG00000013433.1	ENSONIT00000016905.1	ENSONIP00000016890.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.60e-66	223.0	65	491

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw...kskkkavsprellkalkkeaeefsgy 87
           Gl NlgNtC++NS+LQ L+++p++ + l +    +l+   ++ ++++l+++l +l+++l     +++ + +   ll++l+ +  ++s++
   Q: 65   GLLNLGNTCFLNSLLQGLAACPSFIRWLEK--FAALPSI-QSCKDNQLSTTLLQLLKALSsdePGEDDVLDAGCLLDVLRLYRWHISSF 150
           9***************************99..3444433.368899*************866666777999999*************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknk..........slisdlFqgqlksqikclecdnvs.sr 165
           e+qDa+E++++l ++leee    ++ +++++++ ++ e+  +++ek+ +  +             ++ F+g+l+s++ c++c+ +s +r
   Q: 151  EEQDAHELFHVLTSSLEEER--DRQPKVTNLFDMHSLESLPDQDEKTMTCRSraplhpipspWKFQHPFHGRLTSNMFCKRCELQSpVR 237
           ********************..5566666666666555544444444444444666666666999*********************9** PP
   S: 166  eepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqe...............aekklklkklPevLilhLkRfsf 239
           +++f +lsl++p  +   + sl++cL++f + e++++   ++ce+c+k+q+                +k+lkl klP++L++hL+R ++
   Q: 238  YDSFDSLSLSIPLPQWGRPISLDQCLQHFISSETIKE---VECENCTKLQQattingqvvesqrttFVKQLKLGKLPQCLCIHLQRLTW 323
           ***********************************97...9******9999999999999999999*********************** PP
   S: 240  seeqksrekinkkvefpleLdlspfctspeekqke...................................................... 274
           s+e + ++k +++v+f + L+++++ +++++k ++                                                      
   Q: 324  SSE-GTPIKRQEHVQFAEYLSMDHYKHNTSTKRSQrlrctaksikaesrddsvekpsangtdsehhnnnkpfsngtcssvllhtpgvnp 411
           998.999****************999996666655778888888888888888888888888888999999999999999999999999 PP
   S: 275  ...........kkkYeLiavvvHsGslssGHYvayvkn.........ekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
                      ++ ++L+av+vH+G ++sGH+v+y ++          + +Wl ++D++V++ + +evl+   s+aY+lfY+r
   Q: 412  qlsltydysstEYLFQLTAVLVHHGDMHSGHFVTYRRSpsssrssspFSCQWLWVSDDSVRKANLHEVLS---SNAYMLFYER 491
           999999999999999***********************7777766666777*******************...********98 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MLWCRAKSSD KLVREFLGTG PVIRNKMIKN WGVIGGIAAA IAAGVYVLWG PITERKKRKR 60
GMAPGLLNLG NTCFLNSLLQ GLAACPSFIR WLEKFAALPS IQSCKDNQLS TTLLQLLKAL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTAATGACGT TCGAGGCGTG CCACTCTTCC TTGGGTCCGT CCTGAAACAC ACCACTAACC 60
ATTGAGAGTT CCGCAGAAGG AGCAGGATGT TGTGGTGCAG AGCAAAAAGC TCTGATAAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000204	Aegilops tauschii	25.25	3.00e-10	60.10
IUUC-Aml-001733	Ailuropoda melanoleuca	59.08	1.00e-147	516.00
IUUC-Atr-002510	Amborella trichopoda	24.16	3.00e-17	84.00
IUUC-Apl-003645	Anas platyrhynchos	58.15	1.00e-79	289.00
IUUC-Aca-004583	Anolis carolinensis	62.12	2.00e-16	76.60
IUUC-Ath-007622	Arabidopsis thaliana	26.72	1.00e-20	94.70
IUUC-Ani-009286	Aspergillus nidulans	21.98	1.00e-11	65.10
IUUC-Ame-010896	Astyanax mexicanus	74.36	0.00e+00	649.00
IUUC-Bta-012321	Bos taurus	60.77	1.00e-150	526.00
IUUC-Bdi-014795	Brachypodium distachyon	25.90	7.00e-13	68.60
IUUC-Bol-015637	Brassica oleracea	23.51	3.00e-18	86.70
IUUC-Cel-018308	Caenorhabditis elegans	26.45	2.00e-31	130.00
IUUC-Cja-018826	Callithrix jacchus	60.64	3.00e-153	535.00
IUUC-Cfa-021206	Canis familiaris	58.48	1.00e-147	516.00
IUUC-Cpo-021343	Cavia porcellus	58.40	2.00e-149	522.00
IUUC-Csa-023419	Chlorocebus sabaeus	60.56	2.00e-152	532.00
IUUC-Cho-024475	Choloepus hoffmanni	56.04	3.00e-77	282.00
IUUC-Cne-027061	Cryptococcus neoformans	26.69	2.00e-12	68.20
IUUC-Dre-027563	Danio rerio	72.23	0.00e+00	671.00
IUUC-Dno-029929	Dasypus novemcinctus	59.36	3.00e-150	525.00
IUUC-Dor-030166	Dipodomys ordii	53.54	9.00e-94	337.00
IUUC-Dme-031627	Drosophila melanogaster	31.19	4.00e-33	136.00
IUUC-Ete-032634	Echinops telfairi	58.47	3.00e-141	494.00
IUUC-Eca-033968	Equus caballus	60.65	9.00e-149	520.00
IUUC-Eeu-035279	Erinaceus europaeus	66.46	3.00e-45	176.00
IUUC-Fca-036525	Felis catus	59.64	7.00e-154	537.00
IUUC-Fal-036606	Ficedula albicollis	59.89	1.00e-126	446.00
IUUC-Gmo-038726	Gadus morhua	69.01	0.00e+00	632.00
IUUC-Gga-040718	Gallus gallus	62.03	1.00e-127	449.00
IUUC-Gac-042645	Gasterosteus aculeatus	81.49	0.00e+00	764.00
IUUC-Gma-042890	Glycine max	23.93	2.00e-21	97.40
IUUC-Ggo-045021	Gorilla gorilla	59.92	6.00e-153	534.00
IUUC-Hsa-045832	Homo sapiens	59.92	6.00e-153	534.00
IUUC-Itr-048392	Ictidomys tridecemlineatus	60.53	7.00e-147	513.00
IUUC-Lch-050662	Latimeria chalumnae	65.18	2.00e-157	548.00
IUUC-Lpe-051078	Leersia perrieri	25.83	1.00e-23	104.00
IUUC-Loc-052611	Lepisosteus oculatus	69.23	0.00e+00	642.00
IUUC-Laf-053752	Loxodonta africana	60.74	4.00e-146	511.00
IUUC-Mcc-054892	Macaca mulatta	60.36	6.00e-152	530.00
IUUC-Meu-056673	Macropus eugenii	56.33	1.00e-110	393.00
IUUC-Mor-057143	Magnaporthe oryzae	22.68	6.00e-10	59.70
IUUC-Mtr-057976	Medicago truncatula	25.49	8.00e-25	108.00
IUUC-Mla-058970	Melampsora laricipopulina	26.53	2.00e-21	97.80
IUUC-Mga-059543	Meleagris gallopavo	62.90	9.00e-146	509.00
IUUC-Mmr-061534	Microcebus murinus	60.16	6.00e-152	530.00
IUUC-Mdo-062140	Monodelphis domestica	51.22	5.00e-123	434.00
IUUC-Mmu-063673	Mus musculus	59.39	1.00e-146	513.00
IUUC-Mpu-066328	Mustela putorius furo	60.00	1.00e-150	526.00
IUUC-Mlu-067938	Myotis lucifugus	59.68	7.00e-156	543.00
IUUC-Nle-069426	Nomascus leucogenys	58.22	2.00e-134	472.00
IUUC-Opr-070796	Ochotona princeps	54.84	2.00e-64	239.00
IUUC-Oan-072916	Ornithorhynchus anatinus	62.55	2.00e-158	551.00
IUUC-Ocu-074459	Oryctolagus cuniculus	58.29	4.00e-120	424.00
IUUC-Oba-075765	Oryza barthii	26.98	4.00e-22	99.80
IUUC-Obr-076005	Oryza brachyantha	27.93	2.00e-25	110.00
IUUC-Ogl-077916	Oryza glaberrima	27.93	3.00e-26	113.00
IUUC-Ogu-078263	Oryza glumaepatula	26.68	2.00e-22	100.00
IUUC-Oin-080096	Oryza indica	25.82	2.00e-16	80.90
IUUC-Ome-081928	Oryza meridionalis	26.49	4.00e-22	99.80
IUUC-Oni-082424	Oryza nivara	26.57	2.00e-22	100.00
IUUC-Oru-085117	Oryza rufipogon	26.57	2.00e-22	100.00
IUUC-Ola-087429	Oryzias latipes	82.58	0.00e+00	729.00
IUUC-Oga-087981	Otolemur garnettii	59.96	8.00e-153	533.00
IUUC-Oar-089927	Ovis aries	61.21	4.00e-151	528.00
IUUC-Ptr-090878	Pan troglodytes	59.92	6.00e-153	534.00
IUUC-Pan-092698	Papio anubis	60.36	6.00e-152	530.00
IUUC-Psi-093451	Pelodiscus sinensis	62.13	3.00e-152	531.00
IUUC-Ppa-096015	Physcomitrella patens	23.33	1.00e-08	55.50
IUUC-Pfo-096096	Poecilia formosa	84.27	0.00e+00	766.00
IUUC-Pab-098676	Pongo abelii	60.65	1.00e-148	520.00
IUUC-Pca-100418	Procavia capensis	66.67	1.00e-87	317.00
IUUC-Ppe-101898	Prunus persica	25.19	1.00e-22	101.00
IUUC-Pva-103018	Pteropus vampyrus	58.61	1.00e-146	513.00
IUUC-Pgr-103686	Puccinia graminis	23.14	2.00e-10	61.60
IUUC-Pte-104330	Pyrenophora teres	23.05	5.00e-09	56.60
IUUC-Pyt-104518	Pyrenophora triticirepentis	23.23	6.00e-15	76.30
IUUC-Rno-105708	Rattus norvegicus	59.39	3.00e-147	515.00
IUUC-Sha-106971	Sarcophilus harrisii	61.99	2.00e-154	539.00
IUUC-Ssl-108648	Sclerotinia sclerotiorum	22.45	2.00e-11	64.70
IUUC-Sit-110442	Setaria italica	26.06	1.00e-19	91.30
IUUC-Sly-110928	Solanum lycopersicum	22.95	2.00e-11	63.90
IUUC-Stu-112223	Solanum tuberosum	22.60	2.00e-12	67.00
IUUC-Ssc-116397	Sus scrofa	59.84	1.00e-148	520.00
IUUC-Tgu-117446	Taeniopygia guttata	58.85	2.00e-148	518.00
IUUC-Tru-118268	Takifugu rubripes	75.05	0.00e+00	662.00
IUUC-Tsy-119484	Tarsius syrichta	72.29	3.00e-25	109.00
IUUC-Tni-119735	Tetraodon nigroviridis	71.11	3.00e-166	578.00
IUUC-Tca-121660	Theobroma cacao	26.18	4.00e-26	113.00
IUUC-Tae-125383	Triticum aestivum	26.10	2.00e-21	97.40
IUUC-Tur-126458	Triticum urartu	26.17	1.00e-19	91.70
IUUC-Tbe-127740	Tupaia belangeri	55.73	4.00e-131	461.00
IUUC-Ttr-129273	Tursiops truncatus	58.69	5.00e-148	517.00
IUUC-Vvi-131177	Vitis vinifera	24.71	2.00e-23	103.00
IUUC-Xtr-132374	Xenopus tropicalis	59.75	1.00e-153	536.00
IUUC-Xma-133267	Xiphophorus maculatus	85.13	0.00e+00	795.00
IUUC-Zma-135796	Zea mays	27.93	2.00e-18	87.40

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence