iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020121

Ensembl Protein ID

ENSCAFP00000000339.3

UniProt Accession

F6XCZ4; F6XCZ4_CANLF

Genbank Protein ID

ENSCAFP00000000339

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03000187

Gene Name

AHI1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000000234.3	ENSCAFT00000000373.3	ENSCAFP00000000339.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.30e-20	71.6	636	666
UBD/SH3	3.20e-14	52.9	1037	1089

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gH + +++l++ +d ++++++s Dgt ++W 
   Q: 636  GHLNIIYDLCWsNDdRYILTASSDGTARIWK 666
           79999*******777***************7 PP

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           +v +lydy+a+ +deLt+++Gd+++v    + +e+W++g +  +g++G fP+n v+
   Q: 1037 TVVALYDYTANRSDELTIHRGDIIRVF--FKDNEDWWYG-SIGKGQEGYFPANHVA 1089
           689***********************9..8999******.799**********996 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MPTVESEAKV KTRVRFEELL KTHHDLIQER KKLKKKIGKS GEKIALDTVR SNLQKSKETK 60
SDDVSSSNTT NLEKNMPGTK SKLRNSQSTP ENPDDVTVEE DRQWKASKKV IKTVLQMTAQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTGTCAACC TGGTGCTGAA TTTCGAATCT GTGAAATGCC TTCTTAATTA CATCCGAGAA 60
AAGGTGATCA GTGTGCTACA TTTATCGGGG TCGTGTACAG ATAGAAAAAA TTACCCTGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001452--SH3_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50002--SH3
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00018--SH3_1
PF00400--WD40

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3
SM00320--WD40

Gene Ontology

GO:0005912--C:adherens junction
GO:0005911--C:cell-cell junction
GO:0005814--C:centriole
GO:0005813--C:centrosome
GO:0036064--C:ciliary basal body
GO:0005929--C:cilium
GO:0097730--C:non-motile cilium
GO:0034613--P:cellular protein localization
GO:0007417--P:central nervous system development
GO:0060271--P:cilium assembly
GO:0035844--P:cloaca development
GO:0001947--P:heart looping
GO:0030902--P:hindbrain development
GO:0070121--P:Kupffer's vesicle development
GO:0070986--P:left/right axis specification
GO:0001738--P:morphogenesis of a polarized epithelium
GO:0043066--P:negative regulation of apoptotic process
GO:0071599--P:otic vesicle development
GO:0035845--P:photoreceptor cell outer segment organization
GO:0030862--P:positive regulation of polarized epithelial cell differentiation
GO:0002092--P:positive regulation of receptor internalization
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0039023--P:pronephric duct morphogenesis
GO:0039008--P:pronephric nephron tubule morphogenesis
GO:0050795--P:regulation of behavior
GO:0010842--P:retina layer formation
GO:0065001--P:specification of axis polarity
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway
GO:0016192--P:vesicle-mediated transport

KEGG

cfa:476212

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001943	Ailuropoda melanoleuca	91.62	0.00e+00	1802.00
IUUC-Apl-004057	Anas platyrhynchos	49.91	0.00e+00	1052.00
IUUC-Aca-004306	Anolis carolinensis	54.55	0.00e+00	944.00
IUUC-Ame-010981	Astyanax mexicanus	50.66	0.00e+00	843.00
IUUC-Bta-013129	Bos taurus	85.16	0.00e+00	1865.00
IUUC-Cja-018979	Callithrix jacchus	78.56	0.00e+00	1562.00
IUUC-Cpo-022219	Cavia porcellus	77.54	0.00e+00	1303.00
IUUC-Csa-023991	Chlorocebus sabaeus	82.57	0.00e+00	1865.00
IUUC-Cho-024782	Choloepus hoffmanni	80.96	0.00e+00	970.00
IUUC-Cin-025149	Ciona intestinalis	39.64	2.00e-167	582.00
IUUC-Csv-026188	Ciona savignyi	39.41	4.00e-125	441.00
IUUC-Dre-028737	Danio rerio	51.33	0.00e+00	864.00
IUUC-Dno-029756	Dasypus novemcinctus	84.34	0.00e+00	1800.00
IUUC-Dor-030821	Dipodomys ordii	69.25	0.00e+00	1452.00
IUUC-Ete-032237	Echinops telfairi	79.69	0.00e+00	1590.00
IUUC-Eca-033491	Equus caballus	85.07	0.00e+00	1927.00
IUUC-Eeu-034812	Erinaceus europaeus	75.24	0.00e+00	969.00
IUUC-Fca-035868	Felis catus	88.96	0.00e+00	1902.00
IUUC-Fal-037571	Ficedula albicollis	54.90	0.00e+00	785.00
IUUC-Gmo-039358	Gadus morhua	50.58	0.00e+00	800.00
IUUC-Gga-040233	Gallus gallus	53.92	0.00e+00	981.00
IUUC-Gac-041744	Gasterosteus aculeatus	49.38	0.00e+00	802.00
IUUC-Ggo-044766	Gorilla gorilla	82.68	0.00e+00	1908.00
IUUC-Hsa-046660	Homo sapiens	82.36	0.00e+00	1900.00
IUUC-Itr-048282	Ictidomys tridecemlineatus	82.02	0.00e+00	1859.00
IUUC-Loc-052658	Lepisosteus oculatus	48.81	0.00e+00	923.00
IUUC-Laf-053564	Loxodonta africana	87.51	0.00e+00	1476.00
IUUC-Mcc-055480	Macaca mulatta	83.00	0.00e+00	1902.00
IUUC-Meu-056362	Macropus eugenii	57.78	0.00e+00	805.00
IUUC-Mga-060033	Meleagris gallopavo	50.43	0.00e+00	1059.00
IUUC-Mmr-061075	Microcebus murinus	82.57	0.00e+00	1893.00
IUUC-Mdo-062818	Monodelphis domestica	53.85	0.00e+00	1175.00
IUUC-Mmu-063987	Mus musculus	76.92	0.00e+00	1553.00
IUUC-Mpu-066242	Mustela putorius furo	88.29	0.00e+00	1894.00
IUUC-Mlu-067123	Myotis lucifugus	79.55	0.00e+00	1698.00
IUUC-Nle-069793	Nomascus leucogenys	82.34	0.00e+00	1909.00
IUUC-Opr-071110	Ochotona princeps	72.38	0.00e+00	826.00
IUUC-Ont-072179	Oreochromis niloticus	48.53	0.00e+00	827.00
IUUC-Oan-073201	Ornithorhynchus anatinus	64.91	2.00e-138	484.00
IUUC-Ocu-074224	Oryctolagus cuniculus	82.09	0.00e+00	1908.00
IUUC-Ola-086818	Oryzias latipes	53.24	7.00e-73	266.00
IUUC-Oga-088338	Otolemur garnettii	83.85	0.00e+00	1755.00
IUUC-Oar-089247	Ovis aries	82.98	0.00e+00	1875.00
IUUC-Ptr-090830	Pan troglodytes	82.90	0.00e+00	1885.00
IUUC-Pan-092469	Papio anubis	81.70	0.00e+00	1921.00
IUUC-Psi-093183	Pelodiscus sinensis	52.04	0.00e+00	1074.00
IUUC-Pma-094415	Petromyzon marinus	46.89	4.00e-158	551.00
IUUC-Pfo-096577	Poecilia formosa	47.05	0.00e+00	805.00
IUUC-Pab-098236	Pongo abelii	80.93	0.00e+00	1634.00
IUUC-Pca-100560	Procavia capensis	68.39	0.00e+00	1452.00
IUUC-Pva-102565	Pteropus vampyrus	79.23	0.00e+00	1348.00
IUUC-Rno-104881	Rattus norvegicus	76.21	0.00e+00	1575.00
IUUC-Sha-106577	Sarcophilus harrisii	65.48	4.00e-164	570.00
IUUC-Sar-113265	Sorex araneus	73.70	0.00e+00	1551.00
IUUC-Ssc-116174	Sus scrofa	84.98	0.00e+00	1852.00
IUUC-Tgu-116618	Taeniopygia guttata	48.65	0.00e+00	889.00
IUUC-Tru-117761	Takifugu rubripes	43.31	0.00e+00	684.00
IUUC-Tsy-119557	Tarsius syrichta	78.03	0.00e+00	917.00
IUUC-Tni-119782	Tetraodon nigroviridis	50.70	0.00e+00	816.00
IUUC-Tbe-127529	Tupaia belangeri	72.00	7.00e-142	498.00
IUUC-Ttr-128444	Tursiops truncatus	82.38	0.00e+00	1802.00
IUUC-Vpa-130337	Vicugna pacos	76.79	0.00e+00	1617.00
IUUC-Xtr-132055	Xenopus tropicalis	58.49	0.00e+00	753.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence