iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000019986.17	ENSMUST00000105525.11	ENSMUSP00000101164.4
ENSMUSG00000019986.17	ENSMUST00000213104.1	ENSMUSP00000149010.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	miRTarBase	microRNA	TRANSFAC
RepTar	RAID2
Protein-protein Interaction
HINT
Post-translational Modifications (PTMs)
CPLM	PHOSIDA	mUbiSiDa
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-19	70.4	502	532
UBD/SH3	2.40e-15	57.3	907	958

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWD 29
           gH + +++l++  +d++lv++s Dgt +vW 
   Q: 502  GHLNIIYDLDWskDDRYLVTSSSDGTARVWK 532
           79999*******666***************7 PP

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           v +lydy+a+ +deLt+++Gd+++v    + +e+W++g +  +g++G+fP+n v+
   Q: 907  VVALYDYTASRSDELTIHRGDIIRVY--FKDNEDWWYG-SVRKGQEGFFPANHVA 958
           899**********************8..8999******.7************996 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MEPETPEKVD SAQEKVRGKT PTADDSDDSR EKTGIEEKGE LTDAYQLQVA EEMAKEIKKK 60
IRKKLKEQLT YFPPDTLLHD DKLASEKRKK KKKKVPVPTK PESSPSDVCD SAVEGEQKKE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATCTCCCGT CCCTAGTCTG AGTTACCTAG GCAACAGCGG CAGAGGCGGG CCTGACGTCA 60
CGGGCGGCGC GCCTCCGCAC TGCGGCACTG AGCTGGCTGG ACAGCGCGCG TCGCCAGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001452--SH3_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50002--SH3
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00018--SH3_1
PF00400--WD40

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3
SM00320--WD40

Gene Ontology

GO:0005912--C:adherens junction
GO:0005911--C:cell-cell junction
GO:0005813--C:centrosome
GO:0036064--C:ciliary basal body

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001943	Ailuropoda melanoleuca	78.31	0.00e+00	1376.00
IUUC-Apl-004057	Anas platyrhynchos	53.42	0.00e+00	998.00
IUUC-Aca-004306	Anolis carolinensis	54.85	0.00e+00	918.00
IUUC-Ame-010981	Astyanax mexicanus	49.35	0.00e+00	825.00
IUUC-Bta-013129	Bos taurus	79.18	0.00e+00	1559.00
IUUC-Cja-018979	Callithrix jacchus	77.86	0.00e+00	1355.00
IUUC-Cfa-020121	Canis familiaris	76.73	0.00e+00	1575.00
IUUC-Cpo-022219	Cavia porcellus	75.15	0.00e+00	1264.00
IUUC-Csa-023991	Chlorocebus sabaeus	77.73	0.00e+00	1631.00
IUUC-Cho-024782	Choloepus hoffmanni	76.33	0.00e+00	756.00
IUUC-Cin-025149	Ciona intestinalis	40.67	8.00e-171	593.00
IUUC-Csv-026188	Ciona savignyi	39.59	2.00e-124	439.00
IUUC-Dre-028737	Danio rerio	48.74	0.00e+00	816.00
IUUC-Dno-029756	Dasypus novemcinctus	76.69	0.00e+00	1466.00
IUUC-Dor-030821	Dipodomys ordii	69.99	0.00e+00	1352.00
IUUC-Ete-032237	Echinops telfairi	72.06	0.00e+00	1459.00
IUUC-Eca-033491	Equus caballus	78.37	0.00e+00	1611.00
IUUC-Eeu-034812	Erinaceus europaeus	67.43	0.00e+00	855.00
IUUC-Fca-035868	Felis catus	74.37	0.00e+00	1556.00
IUUC-Fal-037571	Ficedula albicollis	55.47	0.00e+00	785.00
IUUC-Gmo-039358	Gadus morhua	50.13	0.00e+00	776.00
IUUC-Gga-040233	Gallus gallus	54.28	0.00e+00	946.00
IUUC-Gac-041744	Gasterosteus aculeatus	48.01	0.00e+00	766.00
IUUC-Ggo-044766	Gorilla gorilla	78.92	0.00e+00	1644.00
IUUC-Hsa-046660	Homo sapiens	78.83	0.00e+00	1641.00
IUUC-Itr-048282	Ictidomys tridecemlineatus	81.93	0.00e+00	1702.00
IUUC-Loc-052658	Lepisosteus oculatus	47.07	0.00e+00	839.00
IUUC-Laf-053564	Loxodonta africana	81.24	0.00e+00	1358.00
IUUC-Mcc-055480	Macaca mulatta	77.44	0.00e+00	1632.00
IUUC-Meu-056362	Macropus eugenii	58.05	0.00e+00	803.00
IUUC-Mga-060033	Meleagris gallopavo	53.76	0.00e+00	986.00
IUUC-Mmr-061075	Microcebus murinus	78.95	0.00e+00	1642.00
IUUC-Mdo-062818	Monodelphis domestica	55.52	0.00e+00	1056.00
IUUC-Mpu-066242	Mustela putorius furo	76.10	0.00e+00	1484.00
IUUC-Mlu-067123	Myotis lucifugus	75.37	0.00e+00	1439.00
IUUC-Nle-069793	Nomascus leucogenys	78.54	0.00e+00	1654.00
IUUC-Opr-071110	Ochotona princeps	72.86	0.00e+00	692.00
IUUC-Ont-072179	Oreochromis niloticus	46.53	0.00e+00	788.00
IUUC-Oan-073201	Ornithorhynchus anatinus	62.68	5.00e-131	460.00
IUUC-Ocu-074224	Oryctolagus cuniculus	81.09	0.00e+00	1695.00
IUUC-Ola-086818	Oryzias latipes	53.24	1.00e-71	262.00
IUUC-Oga-088338	Otolemur garnettii	80.59	0.00e+00	1561.00
IUUC-Oar-089247	Ovis aries	75.88	0.00e+00	1575.00
IUUC-Ptr-090830	Pan troglodytes	79.75	0.00e+00	1615.00
IUUC-Pan-092469	Papio anubis	78.54	0.00e+00	1654.00
IUUC-Psi-093183	Pelodiscus sinensis	55.20	0.00e+00	959.00
IUUC-Pma-094415	Petromyzon marinus	46.72	6.00e-157	547.00
IUUC-Pfo-096577	Poecilia formosa	57.00	0.00e+00	748.00
IUUC-Pab-098236	Pongo abelii	80.18	0.00e+00	1406.00
IUUC-Pca-100560	Procavia capensis	64.30	0.00e+00	1189.00
IUUC-Pva-102565	Pteropus vampyrus	87.56	0.00e+00	1161.00
IUUC-Rno-104881	Rattus norvegicus	92.65	0.00e+00	1920.00
IUUC-Sha-106577	Sarcophilus harrisii	63.80	4.00e-158	550.00
IUUC-Sar-113265	Sorex araneus	66.73	0.00e+00	1274.00
IUUC-Ssc-116174	Sus scrofa	78.24	0.00e+00	1594.00
IUUC-Tgu-116618	Taeniopygia guttata	53.44	0.00e+00	847.00
IUUC-Tru-117761	Takifugu rubripes	42.48	0.00e+00	656.00
IUUC-Tsy-119557	Tarsius syrichta	81.04	0.00e+00	797.00
IUUC-Tni-119782	Tetraodon nigroviridis	49.36	0.00e+00	782.00
IUUC-Tbe-127529	Tupaia belangeri	62.13	7.00e-126	445.00
IUUC-Ttr-128444	Tursiops truncatus	74.91	0.00e+00	1514.00
IUUC-Vpa-130337	Vicugna pacos	68.34	0.00e+00	1326.00
IUUC-Xtr-132055	Xenopus tropicalis	55.46	0.00e+00	717.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence