iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-050357

Ensembl Protein ID

ENSLACP00000020103.1

UniProt Accession

H3BDY2; H3BDY2_LATCH

Genbank Protein ID

ENSLACP00000020103

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01036147

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000017668.1	ENSLACT00000020241.1	ENSLACP00000020103.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.60e-74	251.3	348	967

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 3    lkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgyeq 89
           ++NlgNtCYmN++LQ+L+++++++++ll+   + ++++  k p+++ll+ + +l+++    + + k+   +++++a++++ae+fsgy+q
   Q: 348  FSNLGNTCYMNAILQSLFSLQPFANDLLK---QGIPWK--KIPTNTLLRRFSHLLAKKDvcSPEVKKDLLKKVKNAISATAERFSGYMQ 431
           68***************************...*****9..68*************99977799999999******************** PP
   S: 90   qDaqEflaflldqleeelkk.eknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvp 177
           +Da+Efl+++ldql+e+++k +k+++ e +++e++s+l + ++    + ++++++  ++++++++i+c+ c++  +++e f+dls+++p
   Q: 432  NDAHEFLSQCLDQLKEDMEKlNKTWKSELSSGEESSALRNCEDTIASRVYTCPVVASLEFEVHHSITCKMCGEMVTKREHFNDLSIDLP 520
           ******************8866666666677888888889999999999**************************************** PP
   S: 178  gkeetkke.slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfc 265
           ++++  ++ s+qd+L+ f+++ee+e    y+cekc +k+ a  ++k++klP+vLilhLkR+s++ + + ++k+ ++v +p+ L+l ++c
   Q: 521  RRKKLLTSrSIQDSLDLFFRAEEIE----YSCEKCSGKS-AIVSHKFSKLPRVLILHLKRYSYNVQLSLNSKVRQQVVIPKYLTLLSHC 604
           988765544***************9....********99.9************************************************ PP
   S: 266  ts....................................................................................... 267
           t+                                                                                       
   Q: 605  TEttrppltlgwsmhtamsrplkasqsvnsctvssstparkysfkssssqvvsldsdseeeqlkraishsqrlfeqqqrdqqqeeeeme 693
           ********************************************999999999999999999999999999999999888888888888 PP
   S: 268  ......................................................................................... 267
                                                                                                    
   Q: 694  kaiknsktenekapemadsgfdgmseeellaavlemskretpgllsrveeeeekptnspdtgfgdeelqeltdlsqsmemekpkgaeda 782
           88887777777777777777777777777777777777777777777777777766666666666666666666666666666666666 PP
   S: 268  ................peekqke.................................................................. 274
                           +     +                                                                  
   Q: 783  epgsasemakdsdenkE-----Nktpegtqsdmdwqqqydlerereeqelqqalaqslqeqeareqkedddlkratelslqvefnsfll 866
           66666666665555550.....0555555555666666666666666666666667777777777777778888888888888888888 PP
   S: 275  ....................................kkkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevlee 325
                                               +++Y+Li+vv+H G s+ssGHY+++v + k++ W++++D +V+ ++e++v+++
   Q: 867  egsgsdedsgneevlemeyteneaeelkrnaetgelPHSYRLISVVSHIGsSSSSGHYISDVFDIKKQaWFTYNDLEVSRTQESSVQSD 955
           888888888888889999999999999999999999****************************99999******************** PP
   S: 326  tgstaYvlfYkr 337
           +++++Y++fY +
   Q: 956  RDRSGYIFFYVH 967
           **********86 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MTPMKVHGPI RIRSLQTGTT KWKEGRFEIV EKDNRANLMV HYNAGGSPKT FQNQLNQNIR 60
KVILQMSGAK QQRRLLLMLK NSSSISIDKV PHKDAEELKQ YLETLQQGKF PTVVKSSLGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACCCCAA TGAAAGTGCA TGGTCCCATT AGGATCCGTA GCCTGCAGAC TGGAACTACC 60
AAATGGAAGG AGGGCAGGTT TGAGATTGTT GAGAAGGATA ACCGAGCCAA CTTGATGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR003903--UIM_dom
IPR032069--USP37-like_PH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50330--UIM
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH
PF16674--UCH_N
PF02809--UIM

SMART

SM00726--UIM

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001400	Ailuropoda melanoleuca	65.30	0.00e+00	1068.00
IUUC-Apl-004033	Anas platyrhynchos	67.80	0.00e+00	1141.00
IUUC-Aca-005370	Anolis carolinensis	63.08	0.00e+00	1023.00
IUUC-Ame-011884	Astyanax mexicanus	56.32	0.00e+00	864.00
IUUC-Bta-012725	Bos taurus	64.34	0.00e+00	1049.00
IUUC-Cja-019939	Callithrix jacchus	64.34	0.00e+00	1011.00
IUUC-Cfa-020835	Canis familiaris	65.36	0.00e+00	1087.00
IUUC-Cpo-022067	Cavia porcellus	63.01	0.00e+00	952.00
IUUC-Cre-022867	Chlamydomonas reinhardtii	28.14	6.00e-21	95.90
IUUC-Csa-023085	Chlorocebus sabaeus	64.65	0.00e+00	1048.00
IUUC-Cho-024390	Choloepus hoffmanni	63.01	1.00e-77	285.00
IUUC-Cin-025496	Ciona intestinalis	38.76	3.00e-41	163.00
IUUC-Csv-025812	Ciona savignyi	31.79	1.00e-36	147.00
IUUC-Dre-028255	Danio rerio	55.40	0.00e+00	809.00
IUUC-Dno-028986	Dasypus novemcinctus	64.65	0.00e+00	1041.00
IUUC-Dor-031062	Dipodomys ordii	53.48	2.00e-152	533.00
IUUC-Ete-032359	Echinops telfairi	60.16	2.00e-109	390.00
IUUC-Eca-033964	Equus caballus	65.16	0.00e+00	1071.00
IUUC-Eeu-034492	Erinaceus europaeus	63.25	7.00e-152	531.00
IUUC-Fca-036359	Felis catus	65.36	0.00e+00	1077.00
IUUC-Fal-037640	Ficedula albicollis	67.90	0.00e+00	1105.00
IUUC-Gmo-039600	Gadus morhua	53.81	0.00e+00	807.00
IUUC-Gga-040126	Gallus gallus	67.28	0.00e+00	1071.00
IUUC-Gac-041557	Gasterosteus aculeatus	52.42	0.00e+00	777.00
IUUC-Ggo-045571	Gorilla gorilla	61.41	0.00e+00	895.00
IUUC-Hsa-046043	Homo sapiens	64.54	0.00e+00	1037.00
IUUC-Itr-048207	Ictidomys tridecemlineatus	64.85	0.00e+00	1046.00
IUUC-Loc-052849	Lepisosteus oculatus	60.76	0.00e+00	929.00
IUUC-Laf-054570	Loxodonta africana	64.34	0.00e+00	1022.00
IUUC-Mcc-054989	Macaca mulatta	62.98	0.00e+00	967.00
IUUC-Meu-056273	Macropus eugenii	56.47	4.00e-63	236.00
IUUC-Mga-059814	Meleagris gallopavo	65.43	0.00e+00	1047.00
IUUC-Mmr-061726	Microcebus murinus	65.36	0.00e+00	1045.00
IUUC-Mdo-062974	Monodelphis domestica	67.70	0.00e+00	1130.00
IUUC-Mmu-064069	Mus musculus	63.58	0.00e+00	1009.00
IUUC-Mpu-066008	Mustela putorius furo	64.95	0.00e+00	1042.00
IUUC-Mlu-068224	Myotis lucifugus	43.20	2.00e-95	343.00
IUUC-Nle-069259	Nomascus leucogenys	64.75	0.00e+00	1038.00
IUUC-Opr-070882	Ochotona princeps	63.47	8.00e-103	368.00
IUUC-Ont-072441	Oreochromis niloticus	53.89	0.00e+00	810.00
IUUC-Oan-073151	Ornithorhynchus anatinus	77.66	7.00e-81	293.00
IUUC-Ocu-074879	Oryctolagus cuniculus	64.34	0.00e+00	1033.00
IUUC-Ola-087007	Oryzias latipes	52.54	0.00e+00	775.00
IUUC-Oga-088385	Otolemur garnettii	64.07	0.00e+00	1031.00
IUUC-Oar-090305	Ovis aries	65.06	0.00e+00	1073.00
IUUC-Ptr-091299	Pan troglodytes	64.54	0.00e+00	1036.00
IUUC-Pan-091996	Papio anubis	64.54	0.00e+00	1043.00
IUUC-Psi-093176	Pelodiscus sinensis	68.14	0.00e+00	1139.00
IUUC-Pma-094331	Petromyzon marinus	45.52	0.00e+00	630.00
IUUC-Pfo-096503	Poecilia formosa	54.18	0.00e+00	803.00
IUUC-Pab-098543	Pongo abelii	70.52	4.00e-174	605.00
IUUC-Pca-101099	Procavia capensis	63.27	0.00e+00	796.00
IUUC-Pva-103163	Pteropus vampyrus	60.74	0.00e+00	976.00
IUUC-Rno-105766	Rattus norvegicus	63.58	0.00e+00	1006.00
IUUC-Sha-106610	Sarcophilus harrisii	64.95	0.00e+00	1026.00
IUUC-Sar-113624	Sorex araneus	47.39	2.00e-54	207.00
IUUC-Ssc-116353	Sus scrofa	64.58	0.00e+00	1033.00
IUUC-Tgu-116971	Taeniopygia guttata	67.90	0.00e+00	1097.00
IUUC-Tru-117932	Takifugu rubripes	68.73	6.00e-103	369.00
IUUC-Tsy-119185	Tarsius syrichta	60.65	0.00e+00	699.00
IUUC-Tni-119842	Tetraodon nigroviridis	65.60	9.00e-99	353.00
IUUC-Tbe-127281	Tupaia belangeri	50.34	3.00e-95	343.00
IUUC-Ttr-128177	Tursiops truncatus	68.51	0.00e+00	852.00
IUUC-Vpa-130031	Vicugna pacos	64.65	0.00e+00	1072.00
IUUC-Xtr-132949	Xenopus tropicalis	61.83	0.00e+00	989.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence