iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-010664

Ensembl Protein ID

ENSAMXP00000005514.1

UniProt Accession

W5KD53; W5KD53_ASTMX

Genbank Protein ID

ENSAMXP00000005514

Protein Name

DNA repair protein REV1

Genbank Nucleotide ID

APWO01104811

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000005365.1	ENSAMXT00000005514.1	ENSAMXP00000005514.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBM	2.10e-17	62.4	974	1001

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBM

   S: 1    lPsqvDpeVfsqLPeeiQeEvmaelrqq 28
           +PsqvD +V+++LP e++e+v++ ++++
   Q: 974  SPSQVDRSVLEALPLELREQVEQSWSHR 1001
           7*************************97 PP

Organism

Astyanax mexicanus

Functional Description
(View)

Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.

Protein Sequence
(Fasta)

MSRDGWRKKA SEDDGWGVWG GYMAAKVSKL QEQFQKDAPR EKQNRGASSN IFSGVAIYVN 60
GYTDPSADEL RRLMMLHGGQ FHLYYSRSQT THIIATNLPN SKIKELKEEK VVRPEWITDS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAGGCGGAG CTTCAATGGA AACAACGAGA GGAGGAGCCG GAGGAAGGAG AGGGGCTACA 60
GAGAGCGCTG AACGGCGCCT GGCGATGGAA AGCGGAGATT ATAAGGGGAG AGGGAATCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0237--DNA synthesis
KW-0238--DNA-binding
KW-0548--Nucleotidyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR001357--BRCT_dom
IPR017961--DNA_pol_Y-fam_little_finger
IPR012112--REV1
IPR031991--Rev1_C
IPR001126--UmuC

PROSITE

PS50172--BRCT
PS50173--UMUC

Pfam

PF16589--BRCT_2
PF00817--IMS
PF11799--IMS_C
PF16727--REV1_C

SMART

SM00292--BRCT

Gene Ontology

GO:0005634--C:nucleus
GO:0003684--F:damaged DNA binding
GO:0016779--F:nucleotidyltransferase activity
GO:0042276--P:error-prone translesion synthesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000375	Aegilops tauschii	33.71	7.00e-32	132.00
IUUC-Aml-001185	Ailuropoda melanoleuca	53.86	0.00e+00	876.00
IUUC-Atr-002915	Amborella trichopoda	39.25	4.00e-74	273.00
IUUC-Apl-004054	Anas platyrhynchos	55.36	0.00e+00	880.00
IUUC-Aca-004304	Anolis carolinensis	50.30	0.00e+00	1133.00
IUUC-Aly-005696	Arabidopsis lyrata	43.90	3.00e-75	277.00
IUUC-Ath-006893	Arabidopsis thaliana	44.09	2.00e-76	281.00
IUUC-Ago-007722	Ashbya gossypii	28.68	3.00e-42	167.00
IUUC-Acl-008347	Aspergillus clavatus	36.55	8.00e-77	282.00
IUUC-Afl-008444	Aspergillus flavus	41.72	4.00e-72	266.00
IUUC-Afu-008837	Aspergillus fumigatus	33.61	3.00e-78	286.00
IUUC-Ani-009188	Aspergillus nidulans	39.13	3.00e-73	270.00
IUUC-Ang-009866	Aspergillus niger	35.15	3.00e-80	293.00
IUUC-Aor-010107	Aspergillus oryzae	41.72	4.00e-72	266.00
IUUC-Ate-010359	Aspergillus terreus	34.99	1.00e-81	298.00
IUUC-Bgr-012244	Blumeria graminis	38.26	6.00e-68	252.00
IUUC-Bta-013405	Bos taurus	54.30	0.00e+00	835.00
IUUC-Bci-013849	Botrytis cinerea	33.51	1.00e-79	291.00
IUUC-Bdi-014066	Brachypodium distachyon	41.74	4.00e-77	283.00
IUUC-Bol-015544	Brassica oleracea	31.64	7.00e-83	302.00
IUUC-Bra-017792	Brassica rapa	33.77	3.00e-78	286.00
IUUC-Cel-018148	Caenorhabditis elegans	34.90	2.00e-80	294.00
IUUC-Cja-019742	Callithrix jacchus	42.91	6.00e-144	505.00
IUUC-Cfa-020112	Canis familiaris	49.37	0.00e+00	1078.00
IUUC-Cpo-022152	Cavia porcellus	48.68	0.00e+00	1085.00
IUUC-Cre-022951	Chlamydomonas reinhardtii	38.01	3.00e-44	173.00
IUUC-Csa-023504	Chlorocebus sabaeus	49.59	0.00e+00	1077.00
IUUC-Cho-024780	Choloepus hoffmanni	46.54	2.00e-84	308.00
IUUC-Cin-025276	Ciona intestinalis	52.05	3.00e-100	359.00
IUUC-Csv-026283	Ciona savignyi	41.30	7.00e-106	378.00
IUUC-Cgl-026726	Colletotrichum gloeosporioides	29.75	2.00e-82	300.00
IUUC-Cne-027079	Cryptococcus neoformans	34.88	2.00e-83	304.00
IUUC-Cme-027346	Cyanidioschyzon merolae	28.73	9.00e-45	176.00
IUUC-Dre-028073	Danio rerio	64.76	0.00e+00	1547.00
IUUC-Dno-030038	Dasypus novemcinctus	54.89	0.00e+00	908.00
IUUC-Dor-031100	Dipodomys ordii	50.46	0.00e+00	806.00
IUUC-Dse-031310	Dothistroma septosporum	32.36	1.00e-75	278.00
IUUC-Dme-031991	Drosophila melanogaster	41.34	3.00e-111	396.00
IUUC-Ete-033082	Echinops telfairi	50.64	0.00e+00	773.00
IUUC-Eca-033471	Equus caballus	54.15	0.00e+00	877.00
IUUC-Eeu-034993	Erinaceus europaeus	48.73	0.00e+00	760.00
IUUC-Fca-035367	Felis catus	49.11	0.00e+00	1010.00
IUUC-Fal-036973	Ficedula albicollis	54.92	0.00e+00	844.00
IUUC-Fox-037677	Fusarium oxysporum	29.11	2.00e-78	287.00
IUUC-Fso-038252	Fusarium solani	29.02	2.00e-81	297.00
IUUC-Gmo-039669	Gadus morhua	62.79	0.00e+00	1036.00
IUUC-Ggr-039988	Gaeumannomyces graminis	32.60	3.00e-73	270.00
IUUC-Gga-040423	Gallus gallus	54.89	0.00e+00	884.00
IUUC-Gac-042134	Gasterosteus aculeatus	58.81	0.00e+00	989.00
IUUC-Gma-042929	Glycine max	32.58	3.00e-83	303.00
IUUC-Ggo-044528	Gorilla gorilla	54.23	0.00e+00	868.00
IUUC-Hsa-046259	Homo sapiens	54.12	0.00e+00	860.00
IUUC-Hvu-047139	Hordeum vulgare	44.85	9.00e-46	177.00
IUUC-Itr-048621	Ictidomys tridecemlineatus	49.70	0.00e+00	1093.00
IUUC-Kpa-049169	Komagataella pastoris	36.98	4.00e-61	230.00
IUUC-Lch-050471	Latimeria chalumnae	55.38	0.00e+00	922.00
IUUC-Lpe-050800	Leersia perrieri	34.21	2.00e-78	287.00
IUUC-Loc-052320	Lepisosteus oculatus	49.41	0.00e+00	700.00
IUUC-Lma-053149	Leptosphaeria maculans	33.22	5.00e-82	299.00
IUUC-Laf-053810	Loxodonta africana	54.20	0.00e+00	857.00
IUUC-Mcc-055574	Macaca mulatta	54.53	0.00e+00	859.00
IUUC-Meu-055945	Macropus eugenii	41.82	5.00e-120	426.00
IUUC-Mor-057195	Magnaporthe oryzae	28.03	7.00e-78	286.00
IUUC-Mpo-057488	Magnaporthe poae	32.60	2.00e-73	271.00
IUUC-Mtr-057955	Medicago truncatula	38.16	6.00e-89	322.00
IUUC-Mla-059027	Melampsora laricipopulina	33.07	4.00e-80	292.00
IUUC-Mga-060156	Meleagris gallopavo	54.49	0.00e+00	880.00
IUUC-Mvi-060398	Microbotryum violaceum	34.83	4.00e-77	283.00
IUUC-Mmr-061113	Microcebus murinus	54.89	0.00e+00	866.00
IUUC-Mdo-063001	Monodelphis domestica	56.10	0.00e+00	892.00
IUUC-Mmu-063180	Mus musculus	50.00	0.00e+00	1087.00
IUUC-Mac-065551	Musa acuminata	41.72	2.00e-54	207.00
IUUC-Mpu-066525	Mustela putorius furo	49.23	0.00e+00	1072.00
IUUC-Mlu-067877	Myotis lucifugus	55.08	0.00e+00	880.00
IUUC-Nfi-068418	Neosartorya fischeri	34.34	2.00e-81	297.00
IUUC-Ncr-068648	Neurospora crassa	32.86	3.00e-76	280.00
IUUC-Nle-069959	Nomascus leucogenys	49.30	0.00e+00	1066.00
IUUC-Opr-070522	Ochotona princeps	60.36	8.00e-138	484.00
IUUC-Ont-072293	Oreochromis niloticus	52.99	0.00e+00	1051.00
IUUC-Oan-073519	Ornithorhynchus anatinus	48.50	0.00e+00	1083.00
IUUC-Ocu-074492	Oryctolagus cuniculus	50.06	0.00e+00	779.00
IUUC-Oba-075567	Oryza barthii	33.67	7.00e-79	289.00
IUUC-Obr-076332	Oryza brachyantha	42.58	2.00e-78	287.00
IUUC-Ogl-077348	Oryza glaberrima	33.67	7.00e-79	289.00
IUUC-Ogu-078779	Oryza glumaepatula	33.67	1.00e-78	288.00
IUUC-Oin-079738	Oryza indica	33.91	2.00e-66	247.00
IUUC-Olo-080701	Oryza longistaminata	30.50	9.00e-67	248.00
IUUC-Ome-081708	Oryza meridionalis	33.67	1.00e-79	291.00
IUUC-Oni-082251	Oryza nivara	38.18	2.00e-76	281.00
IUUC-Opu-083528	Oryza punctata	36.55	3.00e-75	276.00
IUUC-Oru-084293	Oryza rufipogon	32.83	1.00e-74	274.00
IUUC-Osa-085549	Oryza sativa	33.67	1.00e-78	288.00
IUUC-Ola-086793	Oryzias latipes	61.04	0.00e+00	1044.00
IUUC-Olu-087786	Ostreococcus lucimarinus	35.89	4.00e-53	202.00
IUUC-Oga-089006	Otolemur garnettii	54.44	0.00e+00	874.00
IUUC-Oar-089597	Ovis aries	49.59	0.00e+00	1063.00
IUUC-Ptr-091520	Pan troglodytes	54.02	0.00e+00	858.00
IUUC-Pan-092333	Papio anubis	54.47	0.00e+00	859.00
IUUC-Psi-094004	Pelodiscus sinensis	50.59	0.00e+00	1101.00
IUUC-Pma-094128	Petromyzon marinus	54.14	2.00e-93	336.00
IUUC-Pno-094849	Phaeosphaeria nodorum	29.53	4.00e-76	280.00
IUUC-Ppa-095714	Physcomitrella patens	31.49	4.00e-84	306.00
IUUC-Pfo-096569	Poecilia formosa	56.71	0.00e+00	1295.00
IUUC-Pab-097960	Pongo abelii	53.91	0.00e+00	853.00
IUUC-Pop-098921	Populus trichocarpa	41.76	1.00e-73	272.00
IUUC-Pca-100509	Procavia capensis	47.80	5.00e-141	495.00
IUUC-Ppe-101730	Prunus persica	36.93	2.00e-83	304.00
IUUC-Pva-102142	Pteropus vampyrus	53.80	0.00e+00	870.00
IUUC-Pgr-103446	Puccinia graminis	32.00	3.00e-69	256.00
IUUC-Ptt-103849	Puccinia triticina	34.69	1.00e-70	262.00
IUUC-Pte-104128	Pyrenophora teres	35.48	2.00e-78	287.00
IUUC-Pyt-104754	Pyrenophora triticirepentis	36.88	9.00e-76	278.00
IUUC-Rno-104871	Rattus norvegicus	49.29	0.00e+00	1099.00
IUUC-Sce-106236	Saccharomyces cerevisiae	26.40	1.00e-41	165.00
IUUC-Sha-106962	Sarcophilus harrisii	49.38	0.00e+00	1085.00
IUUC-Sja-107691	Schizosaccharomyces japonicus	28.29	1.00e-61	231.00
IUUC-Spo-108170	Schizosaccharomyces pombe	34.07	2.00e-65	244.00
IUUC-Ssl-108668	Sclerotinia sclerotiorum	34.49	5.00e-84	306.00
IUUC-Smo-109554	Selaginella moellendorffii	35.66	4.00e-78	286.00
IUUC-Sit-110479	Setaria italica	45.45	3.00e-72	267.00
IUUC-Sly-111752	Solanum lycopersicum	33.85	2.00e-80	294.00
IUUC-Sar-113304	Sorex araneus	49.70	0.00e+00	1048.00
IUUC-Sbi-114196	Sorghum bicolor	39.23	2.00e-76	281.00
IUUC-Sre-115151	Sporisorium reilianum	30.22	1.00e-81	298.00
IUUC-Ssc-116104	Sus scrofa	53.61	0.00e+00	868.00
IUUC-Tgu-117438	Taeniopygia guttata	53.49	0.00e+00	853.00
IUUC-Tru-118553	Takifugu rubripes	54.70	0.00e+00	1263.00
IUUC-Tsy-119056	Tarsius syrichta	53.45	0.00e+00	833.00
IUUC-Tni-119933	Tetraodon nigroviridis	54.39	0.00e+00	961.00
IUUC-Tca-121376	Theobroma cacao	31.93	7.00e-86	312.00
IUUC-Tre-121972	Trichoderma reesei	41.11	2.00e-70	261.00
IUUC-Tvi-122342	Trichoderma virens	32.40	5.00e-70	259.00
IUUC-Tae-123898	Triticum aestivum	28.95	1.00e-89	324.00
IUUC-Tur-126735	Triticum urartu	41.62	2.00e-37	151.00
IUUC-Tme-126999	Tuber melanosporum	32.20	5.00e-74	273.00
IUUC-Tbe-127280	Tupaia belangeri	57.41	2.00e-66	247.00
IUUC-Ttr-129104	Tursiops truncatus	55.39	0.00e+00	864.00
IUUC-Uma-129562	Ustilago maydis	31.11	4.00e-83	303.00
IUUC-Vda-129862	Verticillium dahliae	32.86	1.00e-78	288.00
IUUC-Vpa-130819	Vicugna pacos	56.51	2.00e-110	394.00
IUUC-Vvi-131111	Vitis vinifera	42.35	1.00e-75	278.00
IUUC-Xtr-132629	Xenopus tropicalis	47.35	0.00e+00	1032.00
IUUC-Xma-134065	Xiphophorus maculatus	62.22	0.00e+00	1050.00
IUUC-Yli-134633	Yarrowia lipolytica	37.88	5.00e-54	206.00
IUUC-Zma-135176	Zea mays	38.88	1.00e-80	294.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence