iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	Mentha
Post-translational Modifications (PTMs)
CPLM	dbPAF	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBM	25.78	2.00e-58	223.00	IUUC-Sce-106236

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Drosophila melanogaster

Functional Description
(View)

Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.

Protein Sequence
(Fasta)

MTRDEDNGFS EWGGYFEAKK SKLEEQFAAA SDPFRKSDLF QGISIFVNGR TDPSADELKR 60
IMMVHGGTFH HYERSHTTYI IASVLPDVKV RNMNLSKFIS AKWVVDCLEK KKIVDYKPYL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATAATGAACA TAGGTGTGTC AGCTGAGCGG TATTGGTGGA ATTCAATTTT GGCTTTTTCA 60
TGCTTTTAAA CGATTAAAAA TGACCCGCGA TGAGGATAAT GGTTTTAGTG AATGGGTAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0237--DNA synthesis
KW-0238--DNA-binding
KW-0548--Nucleotidyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR001357--BRCT_dom
IPR017961--DNA_pol_Y-fam_little_finger
IPR012112--REV1
IPR031991--Rev1_C
IPR001126--UmuC

PROSITE

PS50172--BRCT
PS50173--UMUC

Pfam

PF16589--BRCT_2
PF00817--IMS
PF11799--IMS_C
PF16727--REV1_C

SMART

SM00292--BRCT

Gene Ontology

GO:0005634--C:nucleus
GO:0005657--C:replication fork
GO:0003684--F:damaged DNA binding
GO:0017125--F:deoxycytidyl transferase activity
GO:0042276--P:error-prone translesion synthesis
GO:0010569--P:regulation of double-strand break repair via homologous recombination
GO:0019985--P:translesion synthesis

KEGG

dme:Dmel_CG12189

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000375	Aegilops tauschii	33.15	7.00e-22	98.60
IUUC-Aml-001185	Ailuropoda melanoleuca	41.30	7.00e-111	394.00
IUUC-Atr-002915	Amborella trichopoda	31.79	5.00e-75	275.00
IUUC-Apl-004054	Anas platyrhynchos	42.40	8.00e-104	371.00
IUUC-Aca-004304	Anolis carolinensis	42.64	7.00e-112	398.00
IUUC-Aly-005696	Arabidopsis lyrata	30.74	3.00e-86	312.00
IUUC-Ath-006893	Arabidopsis thaliana	31.98	5.00e-94	338.00
IUUC-Ago-007722	Ashbya gossypii	27.32	5.00e-42	165.00
IUUC-Acl-008347	Aspergillus clavatus	29.02	9.00e-90	324.00
IUUC-Afl-008444	Aspergillus flavus	31.89	5.00e-79	288.00
IUUC-Afu-008837	Aspergillus fumigatus	31.00	1.00e-79	291.00
IUUC-Ani-009188	Aspergillus nidulans	29.85	5.00e-88	318.00
IUUC-Ang-009866	Aspergillus niger	31.56	1.00e-86	314.00
IUUC-Aor-010107	Aspergillus oryzae	31.89	7.00e-79	288.00
IUUC-Ate-010359	Aspergillus terreus	31.48	2.00e-84	306.00
IUUC-Ame-010664	Astyanax mexicanus	40.34	5.00e-112	398.00
IUUC-Bgr-012244	Blumeria graminis	28.24	1.00e-66	247.00
IUUC-Bta-013405	Bos taurus	41.82	2.00e-106	379.00
IUUC-Bci-013849	Botrytis cinerea	28.40	8.00e-74	271.00
IUUC-Bdi-014066	Brachypodium distachyon	32.19	1.00e-93	337.00
IUUC-Bol-015544	Brassica oleracea	31.38	2.00e-92	333.00
IUUC-Bra-017792	Brassica rapa	29.72	2.00e-87	316.00
IUUC-Cel-018148	Caenorhabditis elegans	33.40	3.00e-82	299.00
IUUC-Cja-019742	Callithrix jacchus	38.19	2.00e-73	270.00
IUUC-Cfa-020112	Canis familiaris	41.53	3.00e-113	402.00
IUUC-Cpo-022152	Cavia porcellus	41.46	9.00e-113	400.00
IUUC-Cre-022951	Chlamydomonas reinhardtii	39.56	2.00e-33	137.00
IUUC-Csa-023504	Chlorocebus sabaeus	42.34	1.00e-107	384.00
IUUC-Cho-024780	Choloepus hoffmanni	38.55	8.00e-43	168.00
IUUC-Cin-025276	Ciona intestinalis	35.42	3.00e-114	405.00
IUUC-Csv-026283	Ciona savignyi	35.98	3.00e-103	368.00
IUUC-Cgl-026726	Colletotrichum gloeosporioides	31.15	4.00e-80	292.00
IUUC-Cne-027079	Cryptococcus neoformans	33.72	6.00e-71	262.00
IUUC-Cme-027346	Cyanidioschyzon merolae	26.97	4.00e-61	229.00
IUUC-Dre-028073	Danio rerio	41.47	4.00e-104	372.00
IUUC-Dno-030038	Dasypus novemcinctus	42.02	2.00e-112	399.00
IUUC-Dor-031100	Dipodomys ordii	36.88	7.00e-97	348.00
IUUC-Dse-031310	Dothistroma septosporum	30.79	2.00e-80	293.00
IUUC-Ete-033082	Echinops telfairi	37.06	4.00e-88	319.00
IUUC-Eca-033471	Equus caballus	41.21	3.00e-110	392.00
IUUC-Eeu-034993	Erinaceus europaeus	38.60	1.00e-88	320.00
IUUC-Fca-035367	Felis catus	41.62	2.00e-112	400.00
IUUC-Fal-036973	Ficedula albicollis	41.57	3.00e-99	356.00
IUUC-Fox-037677	Fusarium oxysporum	29.80	4.00e-82	298.00
IUUC-Fso-038252	Fusarium solani	28.28	2.00e-92	333.00
IUUC-Gmo-039669	Gadus morhua	32.66	4.00e-114	405.00
IUUC-Ggr-039988	Gaeumannomyces graminis	30.32	4.00e-78	286.00
IUUC-Gga-040423	Gallus gallus	41.12	1.00e-101	363.00
IUUC-Gac-042134	Gasterosteus aculeatus	42.92	3.00e-109	389.00
IUUC-Gma-042929	Glycine max	35.09	2.00e-82	299.00
IUUC-Ggo-044528	Gorilla gorilla	42.94	2.00e-107	383.00
IUUC-Hsa-046259	Homo sapiens	42.94	4.00e-107	382.00
IUUC-Hvu-047139	Hordeum vulgare	30.99	1.00e-59	223.00
IUUC-Itr-048621	Ictidomys tridecemlineatus	41.62	8.00e-113	401.00
IUUC-Kpa-049169	Komagataella pastoris	27.42	2.00e-72	266.00
IUUC-Lch-050471	Latimeria chalumnae	40.56	2.00e-107	383.00
IUUC-Lpe-050800	Leersia perrieri	30.83	3.00e-76	279.00
IUUC-Loc-052320	Lepisosteus oculatus	29.90	2.00e-56	213.00
IUUC-Lma-053149	Leptosphaeria maculans	30.27	5.00e-82	298.00
IUUC-Laf-053810	Loxodonta africana	41.34	5.00e-103	369.00
IUUC-Mcc-055574	Macaca mulatta	42.94	2.00e-107	383.00
IUUC-Meu-055945	Macropus eugenii	37.50	3.00e-53	203.00
IUUC-Mor-057195	Magnaporthe oryzae	29.17	4.00e-81	296.00
IUUC-Mpo-057488	Magnaporthe poae	29.89	1.00e-74	274.00
IUUC-Mtr-057955	Medicago truncatula	30.09	2.00e-91	330.00
IUUC-Mla-059027	Melampsora laricipopulina	32.72	8.00e-88	317.00
IUUC-Mga-060156	Meleagris gallopavo	41.58	2.00e-101	363.00
IUUC-Mvi-060398	Microbotryum violaceum	35.85	7.00e-85	308.00
IUUC-Mmr-061113	Microcebus murinus	41.70	1.00e-105	377.00
IUUC-Mdo-063001	Monodelphis domestica	41.40	1.00e-105	377.00
IUUC-Mmu-063180	Mus musculus	41.82	5.00e-105	375.00
IUUC-Mac-065551	Musa acuminata	36.30	2.00e-42	166.00
IUUC-Mpu-066525	Mustela putorius furo	41.41	1.00e-111	397.00
IUUC-Mlu-067877	Myotis lucifugus	41.85	4.00e-105	375.00
IUUC-Nfi-068418	Neosartorya fischeri	27.84	3.00e-90	326.00
IUUC-Ncr-068648	Neurospora crassa	31.86	2.00e-80	293.00
IUUC-Nle-069959	Nomascus leucogenys	42.94	3.00e-107	382.00
IUUC-Opr-070522	Ochotona princeps	39.95	8.00e-79	288.00
IUUC-Ont-072293	Oreochromis niloticus	35.78	3.00e-105	376.00
IUUC-Oan-073519	Ornithorhynchus anatinus	41.14	5.00e-112	398.00
IUUC-Ocu-074492	Oryctolagus cuniculus	42.68	9.00e-107	380.00
IUUC-Oba-075567	Oryza barthii	34.78	7.00e-80	291.00
IUUC-Obr-076332	Oryza brachyantha	35.41	3.00e-78	286.00
IUUC-Ogl-077348	Oryza glaberrima	34.78	7.00e-80	291.00
IUUC-Ogu-078779	Oryza glumaepatula	32.14	5.00e-80	292.00
IUUC-Oin-079738	Oryza indica	30.09	2.00e-88	319.00
IUUC-Olo-080701	Oryza longistaminata	29.00	5.00e-88	318.00
IUUC-Ome-081708	Oryza meridionalis	31.12	1.00e-78	288.00
IUUC-Oni-082251	Oryza nivara	34.37	2.00e-77	283.00
IUUC-Opu-083528	Oryza punctata	31.84	3.00e-75	276.00
IUUC-Oru-084293	Oryza rufipogon	31.15	2.00e-75	276.00
IUUC-Osa-085549	Oryza sativa	31.78	1.00e-79	290.00
IUUC-Ola-086793	Oryzias latipes	37.52	1.00e-109	390.00
IUUC-Olu-087786	Ostreococcus lucimarinus	28.98	3.00e-63	235.00
IUUC-Oga-089006	Otolemur garnettii	41.57	4.00e-105	375.00
IUUC-Oar-089597	Ovis aries	42.63	1.00e-114	407.00
IUUC-Ptr-091520	Pan troglodytes	42.94	3.00e-107	382.00
IUUC-Pan-092333	Papio anubis	42.94	1.00e-107	384.00
IUUC-Psi-094004	Pelodiscus sinensis	41.38	4.00e-105	375.00
IUUC-Pma-094128	Petromyzon marinus	38.89	6.00e-60	224.00
IUUC-Pno-094849	Phaeosphaeria nodorum	28.64	1.00e-74	274.00
IUUC-Ppa-095714	Physcomitrella patens	29.75	1.00e-91	330.00
IUUC-Pfo-096569	Poecilia formosa	41.01	4.00e-109	389.00
IUUC-Pab-097960	Pongo abelii	43.15	1.00e-106	380.00
IUUC-Pop-098921	Populus trichocarpa	32.29	7.00e-69	254.00
IUUC-Pca-100509	Procavia capensis	39.64	8.00e-79	288.00
IUUC-Ppe-101730	Prunus persica	29.98	9.00e-94	337.00
IUUC-Pva-102142	Pteropus vampyrus	42.36	4.00e-106	379.00
IUUC-Pgr-103446	Puccinia graminis	35.24	3.00e-59	223.00
IUUC-Ptt-103849	Puccinia triticina	30.76	7.00e-62	232.00
IUUC-Pte-104128	Pyrenophora teres	31.81	2.00e-79	290.00
IUUC-Pyt-104754	Pyrenophora triticirepentis	31.10	5.00e-79	288.00
IUUC-Rno-104871	Rattus norvegicus	41.87	1.00e-110	394.00
IUUC-Sce-106236	Saccharomyces cerevisiae	26.40	1.00e-60	227.00
IUUC-Sha-106962	Sarcophilus harrisii	40.52	1.00e-104	374.00
IUUC-Sja-107691	Schizosaccharomyces japonicus	27.00	6.00e-62	231.00
IUUC-Spo-108170	Schizosaccharomyces pombe	27.78	1.00e-76	281.00
IUUC-Ssl-108668	Sclerotinia sclerotiorum	31.58	5.00e-80	292.00
IUUC-Smo-109554	Selaginella moellendorffii	31.97	6.00e-90	325.00
IUUC-Sit-110479	Setaria italica	34.04	3.00e-59	223.00
IUUC-Sly-111752	Solanum lycopersicum	33.06	5.00e-74	272.00
IUUC-Stu-112284	Solanum tuberosum	25.42	3.00e-25	109.00
IUUC-Sar-113304	Sorex araneus	41.62	3.00e-108	386.00
IUUC-Sbi-114196	Sorghum bicolor	37.54	3.00e-57	216.00
IUUC-Sre-115151	Sporisorium reilianum	30.70	2.00e-69	257.00
IUUC-Ssc-116104	Sus scrofa	41.77	2.00e-105	376.00
IUUC-Tgu-117438	Taeniopygia guttata	41.78	1.00e-100	361.00
IUUC-Tru-118553	Takifugu rubripes	40.23	9.00e-106	377.00
IUUC-Tsy-119056	Tarsius syrichta	42.06	4.00e-106	379.00
IUUC-Tni-119933	Tetraodon nigroviridis	39.88	2.00e-108	386.00
IUUC-Tca-121376	Theobroma cacao	30.25	2.00e-76	280.00
IUUC-Tre-121972	Trichoderma reesei	28.27	1.00e-87	317.00
IUUC-Tvi-122342	Trichoderma virens	28.56	6.00e-85	308.00
IUUC-Tae-123898	Triticum aestivum	30.43	4.00e-80	292.00
IUUC-Tur-126735	Triticum urartu	23.72	9.00e-28	118.00
IUUC-Tme-126999	Tuber melanosporum	30.30	3.00e-69	256.00
IUUC-Tbe-127280	Tupaia belangeri	45.14	1.00e-32	134.00
IUUC-Ttr-129104	Tursiops truncatus	41.80	9.00e-106	377.00
IUUC-Uma-129562	Ustilago maydis	30.83	3.00e-69	256.00
IUUC-Vda-129862	Verticillium dahliae	30.88	6.00e-82	298.00
IUUC-Vpa-130819	Vicugna pacos	43.58	9.00e-65	241.00
IUUC-Vvi-131111	Vitis vinifera	31.78	3.00e-75	276.00
IUUC-Xtr-132629	Xenopus tropicalis	39.10	6.00e-94	338.00
IUUC-Xma-134065	Xiphophorus maculatus	39.85	3.00e-106	379.00
IUUC-Yli-134633	Yarrowia lipolytica	30.82	3.00e-57	216.00
IUUC-Zma-135176	Zea mays	33.97	8.00e-75	274.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence