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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046023
Ensembl Protein ID ENSP00000421633.1
UniProt Accession D6REX3; D6REX3_HUMAN
Genbank Protein ID ENSP00000421633
Protein Name Protein transport protein Sec31A
Genbank Nucleotide ID AC021105
Gene Name SEC31A
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000138674.16 ENST00000503937.5 ENSP00000422371.1
ENSG00000138674.16 ENST00000348405.8 ENSP00000337602.5
ENSG00000138674.16 ENST00000513858.5 ENSP00000426886.1
ENSG00000138674.16 ENST00000395310.6 ENSP00000378721.2
ENSG00000138674.16 ENST00000443462.6 ENSP00000408027.2
ENSG00000138674.16 ENST00000509142.5 ENSP00000426569.1
ENSG00000138674.16 ENST00000505472.5 ENSP00000421633.1
ENSG00000138674.16 ENST00000508502.5 ENSP00000424635.1
ENSG00000138674.16 ENST00000515062.5 ENSP00000426943.1
ENSG00000138674.16 ENST00000264405.9 ENSP00000264405.5
ENSG00000138674.16 ENST00000505984.5 ENSP00000424451.1
ENSG00000138674.16 ENST00000511338.1 ENSP00000425140.1
ENSG00000138674.16 ENST00000508479.5 ENSP00000425999.1
ENSG00000138674.16 ENST00000507828.5 ENSP00000426562.1
ENSG00000138674.16 ENST00000512664.5 ENSP00000424336.1
ENSG00000138674.16 ENST00000510167.1 ENSP00000422267.1
ENSG00000138674.16 ENST00000503058.5 ENSP00000425056.1
ENSG00000138674.16 ENST00000507816.5 ENSP00000421001.1
ENSG00000138674.16 ENST00000507340.5 ENSP00000422797.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBasecircRNADb
CircNetmiRTarBasemicroRNATRANSFAC
RepTarSomamiRmiRcodeRAID2
Protein-protein Interaction
HINTInWeb_IM
Disease-associated Variation
GWASdbOMIM
Post-translational Modifications (PTMs)
CPLMPHOSIDABioGRIDmUbiSiDa
DNA Methylation
TCGAICGC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.10e-19 71.4 170 202
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 5    svtclaf..sd.tllvsGsdDgtikvWDlrtgv 34
           +++c+a+  +  ++l+s+s  g   vWDlr++ 
   Q: 170  DISCIAWnrQVqHILASASPSGRATVWDLRKNE 202
           69*****97334889**************9875 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MKLKEVDRTA MQAWSPAQNH PIYLATGTSA QQLDATFSTN ASLEIFELDL SDPSLDMKSC 60
ATFSSSHRYH KLIWGPYKMD SKGDVSGVLI AGGENGNIIL YDPSKIIAGD KEVVIAQNDK 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046023|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AATAAGACCA TCCAATTAAT GGAGGACTCC TTTCGCGTAA CTCTCCTTAA AGCGGTAGGC 60
GGTGCGAGAA CCGGCTATTC AGAGGTAAAC ACTGGGCGGG AAGAGAGAGA ATCTCAATTC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046023|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat
Interpro

IPR024298--ACE1_Sec16_Sec31
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF12931--Sec16_C
SMART

SM00320--WD40
Gene Ontology

GO:0005829--C:cytosol
GO:0043231--C:intracellular membrane-bounded organelle
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000990 Aegilops tauschii 34.87 8.00e-98 352.00
IUUC-Aml-002270 Ailuropoda melanoleuca 94.41 0.00e+00 2161.00
IUUC-Atr-002489 Amborella trichopoda 39.29 8.00e-70 257.00
IUUC-Apl-004104 Anas platyrhynchos 79.39 0.00e+00 1385.00
IUUC-Aca-005195 Anolis carolinensis 75.49 0.00e+00 1328.00
IUUC-Aly-005977 Arabidopsis lyrata 32.73 3.00e-122 433.00
IUUC-Ath-007685 Arabidopsis thaliana 31.38 8.00e-123 435.00
IUUC-Ago-007906 Ashbya gossypii 24.50 4.00e-60 227.00
IUUC-Acl-008051 Aspergillus clavatus 31.70 2.00e-120 427.00
IUUC-Afl-008442 Aspergillus flavus 32.55 9.00e-116 412.00
IUUC-Afu-009123 Aspergillus fumigatus 31.80 8.00e-124 438.00
IUUC-Ani-009261 Aspergillus nidulans 32.06 1.00e-121 431.00
IUUC-Ang-009822 Aspergillus niger 31.56 1.00e-115 411.00
IUUC-Aor-010011 Aspergillus oryzae 31.85 1.00e-111 398.00
IUUC-Ate-010245 Aspergillus terreus 32.06 1.00e-112 401.00
IUUC-Ame-011240 Astyanax mexicanus 75.31 0.00e+00 733.00
IUUC-Bgr-012053 Blumeria graminis 31.42 5.00e-118 419.00
IUUC-Bta-013464 Bos taurus 84.44 0.00e+00 1975.00
IUUC-Bci-013707 Botrytis cinerea 31.91 5.00e-123 436.00
IUUC-Bdi-014514 Brachypodium distachyon 33.13 1.00e-109 391.00
IUUC-Bol-015890 Brassica oleracea 32.96 1.00e-124 441.00
IUUC-Bra-017330 Brassica rapa 32.99 4.00e-124 439.00
IUUC-Cja-019218 Callithrix jacchus 94.15 0.00e+00 2170.00
IUUC-Cfa-021113 Canis familiaris 92.42 0.00e+00 2133.00
IUUC-Cpo-021694 Cavia porcellus 88.65 0.00e+00 2001.00
IUUC-Cre-022941 Chlamydomonas reinhardtii 34.98 2.00e-89 324.00
IUUC-Csa-024264 Chlorocebus sabaeus 96.56 0.00e+00 2155.00
IUUC-Cho-024699 Choloepus hoffmanni 83.18 0.00e+00 707.00
IUUC-Cin-025764 Ciona intestinalis 49.05 0.00e+00 754.00
IUUC-Csv-025902 Ciona savignyi 49.02 0.00e+00 772.00
IUUC-Cgl-026568 Colletotrichum gloeosporioides 30.07 2.00e-113 404.00
IUUC-Cne-027066 Cryptococcus neoformans 36.12 9.00e-92 332.00
IUUC-Cme-027190 Cyanidioschyzon merolae 32.99 3.00e-60 227.00
IUUC-Dre-028602 Danio rerio 63.89 0.00e+00 1059.00
IUUC-Dno-029236 Dasypus novemcinctus 93.29 0.00e+00 2182.00
IUUC-Dor-030540 Dipodomys ordii 76.14 0.00e+00 1310.00
IUUC-Dse-031424 Dothistroma septosporum 32.15 6.00e-111 395.00
IUUC-Dme-032137 Drosophila melanogaster 37.36 3.00e-162 566.00
IUUC-Ete-032816 Echinops telfairi 76.55 0.00e+00 1113.00
IUUC-Eca-033906 Equus caballus 93.78 0.00e+00 2140.00
IUUC-Fca-035938 Felis catus 91.29 0.00e+00 2037.00
IUUC-Fal-036790 Ficedula albicollis 75.58 0.00e+00 1776.00
IUUC-Fox-037759 Fusarium oxysporum 32.45 3.00e-127 450.00
IUUC-Fso-038391 Fusarium solani 32.65 1.00e-124 441.00
IUUC-Gmo-039663 Gadus morhua 59.30 0.00e+00 954.00
IUUC-Ggr-039903 Gaeumannomyces graminis 30.22 4.00e-108 386.00
IUUC-Gga-040348 Gallus gallus 73.22 0.00e+00 1764.00
IUUC-Gac-042083 Gasterosteus aculeatus 66.88 0.00e+00 1060.00
IUUC-Gma-043831 Glycine max 33.77 3.00e-121 430.00
IUUC-Ggo-044476 Gorilla gorilla 87.27 0.00e+00 1905.00
IUUC-Hvu-047106 Hordeum vulgare 33.80 8.00e-105 375.00
IUUC-Kpa-049364 Komagataella pastoris 26.99 3.00e-86 313.00
IUUC-Lch-050180 Latimeria chalumnae 77.42 0.00e+00 1348.00
IUUC-Lpe-051712 Leersia perrieri 29.77 7.00e-81 295.00
IUUC-Loc-052718 Lepisosteus oculatus 65.89 0.00e+00 1215.00
IUUC-Lma-053135 Leptosphaeria maculans 32.05 2.00e-120 427.00
IUUC-Laf-053769 Loxodonta africana 94.24 0.00e+00 2165.00
IUUC-Mcc-055683 Macaca mulatta 95.76 0.00e+00 2126.00
IUUC-Meu-056623 Macropus eugenii 64.58 0.00e+00 897.00
IUUC-Mor-057177 Magnaporthe oryzae 30.31 2.00e-110 394.00
IUUC-Mpo-057504 Magnaporthe poae 30.78 1.00e-110 394.00
IUUC-Mtr-058313 Medicago truncatula 33.62 9.00e-120 425.00
IUUC-Mla-059047 Melampsora laricipopulina 33.83 7.00e-80 293.00
IUUC-Mga-060201 Meleagris gallopavo 73.56 0.00e+00 1732.00
IUUC-Mvi-060241 Microbotryum violaceum 32.80 3.00e-77 284.00
IUUC-Mmr-060670 Microcebus murinus 73.71 0.00e+00 1249.00
IUUC-Mdo-061894 Monodelphis domestica 80.52 0.00e+00 1875.00
IUUC-Mmu-063627 Mus musculus 87.82 0.00e+00 2084.00
IUUC-Mac-065074 Musa acuminata 31.71 2.00e-114 407.00
IUUC-Mpu-066535 Mustela putorius furo 91.70 0.00e+00 2157.00
IUUC-Mlu-067750 Myotis lucifugus 89.27 0.00e+00 2093.00
IUUC-Nfi-068529 Neosartorya fischeri 31.91 6.00e-122 432.00
IUUC-Ncr-068959 Neurospora crassa 32.83 1.00e-117 418.00
IUUC-Nle-070029 Nomascus leucogenys 96.64 0.00e+00 2192.00
IUUC-Opr-070663 Ochotona princeps 88.56 0.00e+00 1988.00
IUUC-Ont-072481 Oreochromis niloticus 59.30 0.00e+00 962.00
IUUC-Ocu-073975 Oryctolagus cuniculus 93.24 0.00e+00 2123.00
IUUC-Oba-075929 Oryza barthii 33.29 1.00e-112 401.00
IUUC-Obr-076078 Oryza brachyantha 32.81 1.00e-111 397.00
IUUC-Ogl-077519 Oryza glaberrima 33.29 5.00e-113 402.00
IUUC-Ogu-077980 Oryza glumaepatula 33.17 1.00e-112 401.00
IUUC-Oin-079946 Oryza indica 33.33 2.00e-112 400.00
IUUC-Olo-080277 Oryza longistaminata 28.66 9.00e-73 268.00
IUUC-Ome-081551 Oryza meridionalis 32.22 1.00e-104 374.00
IUUC-Oni-082399 Oryza nivara 33.17 2.00e-112 400.00
IUUC-Opu-083645 Oryza punctata 32.10 1.00e-103 371.00
IUUC-Oru-084591 Oryza rufipogon 32.38 3.00e-105 377.00
IUUC-Osa-085698 Oryza sativa 33.21 5.00e-113 402.00
IUUC-Ola-087264 Oryzias latipes 65.81 0.00e+00 1113.00
IUUC-Olu-087684 Ostreococcus lucimarinus 33.66 3.00e-122 432.00
IUUC-Oga-088467 Otolemur garnettii 93.54 0.00e+00 2089.00
IUUC-Oar-090211 Ovis aries 93.06 0.00e+00 2157.00
IUUC-Ptr-091599 Pan troglodytes 97.28 0.00e+00 2237.00
IUUC-Pan-092465 Papio anubis 95.44 0.00e+00 2051.00
IUUC-Pma-094185 Petromyzon marinus 60.38 0.00e+00 882.00
IUUC-Pno-095056 Phaeosphaeria nodorum 30.22 2.00e-102 367.00
IUUC-Ppa-095742 Physcomitrella patens 32.79 3.00e-124 439.00
IUUC-Pfo-096678 Poecilia formosa 58.56 0.00e+00 951.00
IUUC-Pab-098610 Pongo abelii 77.24 0.00e+00 1577.00
IUUC-Pop-099456 Populus trichocarpa 33.33 2.00e-98 353.00
IUUC-Pca-100826 Procavia capensis 82.29 0.00e+00 1458.00
IUUC-Ppe-101423 Prunus persica 31.45 1.00e-114 407.00
IUUC-Pva-102904 Pteropus vampyrus 89.23 0.00e+00 2105.00
IUUC-Pgr-103294 Puccinia graminis 33.21 5.00e-82 300.00
IUUC-Ptt-103927 Puccinia triticina 28.88 2.00e-64 241.00
IUUC-Pte-104145 Pyrenophora teres 31.45 7.00e-113 402.00
IUUC-Pyt-104813 Pyrenophora triticirepentis 32.00 7.00e-115 409.00
IUUC-Rno-105317 Rattus norvegicus 89.62 0.00e+00 2034.00
IUUC-Sce-106253 Saccharomyces cerevisiae 26.40 5.00e-71 263.00
IUUC-Sha-106950 Sarcophilus harrisii 84.09 0.00e+00 1935.00
IUUC-Sja-107881 Schizosaccharomyces japonicus 27.74 9.00e-77 282.00
IUUC-Spo-108124 Schizosaccharomyces pombe 28.73 2.00e-85 311.00
IUUC-Ssl-108487 Sclerotinia sclerotiorum 32.01 8.00e-123 435.00
IUUC-Smo-108717 Selaginella moellendorffii 32.04 4.00e-107 382.00
IUUC-Sit-110339 Setaria italica 32.33 5.00e-109 389.00
IUUC-Sly-111112 Solanum lycopersicum 40.62 4.00e-73 270.00
IUUC-Sar-112974 Sorex araneus 81.06 0.00e+00 1696.00
IUUC-Sbi-114012 Sorghum bicolor 33.71 4.00e-114 406.00
IUUC-Sre-114994 Sporisorium reilianum 36.61 3.00e-91 330.00
IUUC-Ssc-116082 Sus scrofa 89.94 0.00e+00 2117.00
IUUC-Tgu-116721 Taeniopygia guttata 73.61 0.00e+00 1709.00
IUUC-Tru-118400 Takifugu rubripes 63.09 0.00e+00 1108.00
IUUC-Tsy-119317 Tarsius syrichta 83.57 0.00e+00 1381.00
IUUC-Tni-120382 Tetraodon nigroviridis 65.75 0.00e+00 1095.00
IUUC-Tca-121760 Theobroma cacao 33.45 2.00e-126 447.00
IUUC-Tre-122238 Trichoderma reesei 32.49 1.00e-124 441.00
IUUC-Tvi-122298 Trichoderma virens 32.23 2.00e-125 444.00
IUUC-Tae-125709 Triticum aestivum 33.33 1.00e-111 398.00
IUUC-Tur-126767 Triticum urartu 34.60 1.00e-96 348.00
IUUC-Tme-127067 Tuber melanosporum 32.51 3.00e-123 436.00
IUUC-Tbe-127689 Tupaia belangeri 79.15 0.00e+00 737.00
IUUC-Ttr-128635 Tursiops truncatus 89.41 0.00e+00 1206.00
IUUC-Uma-129418 Ustilago maydis 35.85 4.00e-89 323.00
IUUC-Vda-129667 Verticillium dahliae 32.86 1.00e-36 146.00
IUUC-Vpa-130428 Vicugna pacos 91.46 0.00e+00 2084.00
IUUC-Vvi-131047 Vitis vinifera 33.74 2.00e-122 433.00
IUUC-Xtr-131857 Xenopus tropicalis 74.82 0.00e+00 1218.00
IUUC-Xma-133717 Xiphophorus maculatus 58.49 0.00e+00 944.00
IUUC-Yli-134526 Yarrowia lipolytica 32.85 3.00e-60 227.00
IUUC-Zma-135604 Zea mays 33.69 2.00e-119 424.00
Created Date 25-Jun-2017

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