iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-022522

Ensembl Protein ID

ENSCPOP00000006053.2

UniProt Accession

P60518; Q9JJ97; GBRL1_CAVPO

Genbank Protein ID

AAL32264.1; AAK28484.1

Protein Name

Gamma-aminobutyric acid receptor-associated protein-like 1; GABA(A) receptor-associated protein-like 1; Glandular epithelial cell protein 1

Genbank Nucleotide ID

AF012920; AF312680

Gene Name

Gabarapl1; GABARAPL1; GEC1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000006718.3	ENSCPOT00000006786.2	ENSCPOP00000006053.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UBL/ATG8	1.50e-53	179.3	14	116

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UBL/ATG8

   S: 2    rkeevekirdkfpdkiPvivekakkekipeldkkkylvPsdltvgqlvkiirkrlqlraedalfllvnnslvsvsatlaeiyeeekded 90
           rk+e+ekir+k+pd++Pviveka+k+++p+ldk+kylvPsdltvgq++++irkr++lr+edalf++vnn+++++sat++++ye++++ed
   Q: 14   RKKEGEKIRKKYPDRVPVIVEKAPKARVPDLDKRKYLVPSDLTVGQFYFLIRKRIHLRPEDALFFFVNNTIPPTSATMGQLYEDNHEED 102
           89*************************************************************************************** PP
   S: 91   gflyvayaseetfG 104
           +flyvay++e+++G
   Q: 103  YFLYVAYSDESVYG 116
           *************9 PP

Organism

Cavia porcellus

Functional Description
(View)

Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Involved in formation of autophagosomal vacuoles. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity).

Protein Sequence
(Fasta)

MKFQYKEDHP FEYRKKEGEK IRKKYPDRVP VIVEKAPKAR VPDLDKRKYL VPSDLTVGQF 60
YFLIRKRIHL RPEDALFFFV NNTIPPTSAT MGQLYEDNHE EDYFLYVAYS DESVYGK 117

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGTGCAATC TAGCGCGCTG GGGGCGTGGC GTGGGCGGGT CAACGTGACG TCACAACACC 60
GCCGCACCGC CCCCGTGTTT TTGTGCTCCT GCTCGCGGGG AAGCCTCTGG GAATTTTTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0072--Autophagy
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0206--Cytoskeleton
KW-0256--Endoplasmic reticulum
KW-0333--Golgi apparatus
KW-0449--Lipoprotein
KW-0472--Membrane
KW-0493--Microtubule
KW-1185--Reference proteome

Interpro

IPR004241--Atg8-like
IPR029071--Ubiquitin-rel_dom

Pfam

PF02991--Atg8

Gene Ontology

GO:0005776--C:autophagosome
GO:0030659--C:cytoplasmic vesicle membrane
GO:0005783--C:endoplasmic reticulum
GO:0005794--C:Golgi apparatus
GO:0005874--C:microtubule
GO:0005739--C:mitochondrion
GO:0006914--P:autophagy

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002173	Ailuropoda melanoleuca	100.00	6.00e-65	238.00
IUUC-Apl-003994	Anas platyrhynchos	100.00	1.00e-64	237.00
IUUC-Aca-004544	Anolis carolinensis	94.87	4.00e-60	222.00
IUUC-Ame-010914	Astyanax mexicanus	86.32	4.00e-57	212.00
IUUC-Bta-012584	Bos taurus	100.00	5.00e-65	238.00
IUUC-Cel-018200	Caenorhabditis elegans	78.45	2.00e-51	194.00
IUUC-Cja-019701	Callithrix jacchus	100.00	5.00e-65	238.00
IUUC-Cfa-020883	Canis familiaris	100.00	5.00e-65	238.00
IUUC-Csa-024162	Chlorocebus sabaeus	100.00	5.00e-65	238.00
IUUC-Cho-025008	Choloepus hoffmanni	95.73	7.00e-62	228.00
IUUC-Cin-025297	Ciona intestinalis	83.62	3.00e-55	206.00
IUUC-Cne-026889	Cryptococcus neoformans	54.31	2.00e-36	144.00
IUUC-Dre-028351	Danio rerio	87.18	1.00e-58	218.00
IUUC-Dno-030014	Dasypus novemcinctus	100.00	3.00e-65	239.00
IUUC-Dor-030245	Dipodomys ordii	87.07	4.00e-57	212.00
IUUC-Dme-031813	Drosophila melanogaster	85.34	1.00e-56	210.00
IUUC-Ete-032671	Echinops telfairi	86.21	9.00e-57	211.00
IUUC-Eca-033464	Equus caballus	100.00	5.00e-65	238.00
IUUC-Eeu-034826	Erinaceus europaeus	76.92	2.00e-46	176.00
IUUC-Fca-036435	Felis catus	100.00	2.00e-64	237.00
IUUC-Fal-037143	Ficedula albicollis	100.00	1.00e-64	237.00
IUUC-Gmo-039671	Gadus morhua	86.32	5.00e-57	212.00
IUUC-Gga-040919	Gallus gallus	100.00	5.00e-65	238.00
IUUC-Gac-042507	Gasterosteus aculeatus	87.07	2.00e-57	213.00
IUUC-Gma-044021	Glycine max	57.39	4.00e-38	149.00
IUUC-Ggo-044931	Gorilla gorilla	100.00	5.00e-65	238.00
IUUC-Hsa-046493	Homo sapiens	100.00	5.00e-65	238.00
IUUC-Itr-048838	Ictidomys tridecemlineatus	100.00	1.00e-64	237.00
IUUC-Lch-049798	Latimeria chalumnae	76.72	2.00e-51	193.00
IUUC-Loc-052290	Lepisosteus oculatus	87.07	4.00e-57	213.00
IUUC-Laf-054083	Loxodonta africana	100.00	4.00e-65	239.00
IUUC-Mcc-055410	Macaca mulatta	100.00	5.00e-65	238.00
IUUC-Meu-056010	Macropus eugenii	100.00	5.00e-65	238.00
IUUC-Mga-060108	Meleagris gallopavo	100.00	1.00e-64	237.00
IUUC-Mmr-060690	Microcebus murinus	100.00	5.00e-65	238.00
IUUC-Mdo-062279	Monodelphis domestica	100.00	2.00e-65	240.00
IUUC-Mmu-063624	Mus musculus	100.00	5.00e-65	238.00
IUUC-Mpu-066745	Mustela putorius furo	100.00	6.00e-65	238.00
IUUC-Mlu-067166	Myotis lucifugus	87.07	4.00e-57	212.00
IUUC-Nle-069220	Nomascus leucogenys	87.07	4.00e-57	212.00
IUUC-Opr-070777	Ochotona princeps	87.07	5.00e-57	212.00
IUUC-Oan-073612	Ornithorhynchus anatinus	98.85	6.00e-47	177.00
IUUC-Ocu-073934	Oryctolagus cuniculus	100.00	5.00e-65	238.00
IUUC-Ola-086391	Oryzias latipes	79.82	1.00e-47	181.00
IUUC-Oga-088360	Otolemur garnettii	100.00	5.00e-65	238.00
IUUC-Oar-089396	Ovis aries	100.00	9.00e-65	238.00
IUUC-Ptr-091136	Pan troglodytes	94.87	9.00e-61	224.00
IUUC-Psi-093055	Pelodiscus sinensis	100.00	5.00e-65	238.00
IUUC-Pfo-096947	Poecilia formosa	61.54	5.00e-32	129.00
IUUC-Pab-097660	Pongo abelii	87.07	4.00e-57	212.00
IUUC-Pca-100230	Procavia capensis	87.07	4.00e-57	212.00
IUUC-Pva-103103	Pteropus vampyrus	100.00	5.00e-65	238.00
IUUC-Rno-105347	Rattus norvegicus	100.00	5.00e-65	238.00
IUUC-Sha-106802	Sarcophilus harrisii	100.00	4.00e-65	239.00
IUUC-Sar-113670	Sorex araneus	81.03	2.00e-52	196.00
IUUC-Ssc-115683	Sus scrofa	99.15	1.00e-64	237.00
IUUC-Tgu-116669	Taeniopygia guttata	100.00	6.00e-65	238.00
IUUC-Tru-118632	Takifugu rubripes	87.07	1.00e-57	214.00
IUUC-Tsy-118919	Tarsius syrichta	100.00	5.00e-65	238.00
IUUC-Tca-121335	Theobroma cacao	58.26	6.00e-34	136.00
IUUC-Tbe-128099	Tupaia belangeri	76.92	2.00e-46	176.00
IUUC-Ttr-128712	Tursiops truncatus	100.00	5.00e-65	238.00
IUUC-Vpa-130227	Vicugna pacos	100.00	2.00e-47	179.00
IUUC-Xtr-132183	Xenopus tropicalis	100.00	4.00e-65	239.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence