iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA
Post-translational Modifications (PTMs)
CPLM	dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E2/Other	79.27	6.00e-80	293.00	IUUC-Hsa-046948

Active Site

Position(s)	Description	Evidence
116	Glycyl thioester intermediate	{ECO:0000250}

Organism

Drosophila melanogaster

Functional Description
(View)

E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage.

Protein Sequence
(Fasta)

MVDDSTRKTL SNIPLLQIRA GPREKDVWVQ RLKEEYQALI KYVENNKQSG SDWFRLESNK 60
EGTKWFGKCW YMHNLLKYEF DVEFDIPVTY PTTAPEIALP ELDGKTAKMY RGGKICLTDH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTCACTTGT CTCTCTCGCA CACATAATCG TGAACGTGTC AAGCGAAGGC TTTTGTTTTC 60
GTTCCGCATT TTCCTTACTT TTGGCTATTT TCCGGACGAG ATGGTGGACG ACAGCACTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR016135--UBQ-conjugating_enzyme/RWD
IPR014806--Ufc1

Pfam

PF08694--UFC1

Gene Ontology

GO:0005737--C:cytoplasm
GO:0071568--F:UFM1 transferase activity
GO:0046331--P:lateral inhibition
GO:0031987--P:locomotion involved in locomotory behavior
GO:1990592--P:protein K69-linked ufmylation
GO:0050808--P:synapse organization

KEGG

dme:Dmel_CG8386

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000219	Aegilops tauschii	70.89	9.00e-32	127.00
IUUC-Aml-001773	Ailuropoda melanoleuca	78.05	2.00e-80	290.00
IUUC-Atr-002519	Amborella trichopoda	68.32	1.00e-68	251.00
IUUC-Aca-004597	Anolis carolinensis	79.27	8.00e-79	284.00
IUUC-Aly-005549	Arabidopsis lyrata	66.67	5.00e-66	242.00
IUUC-Ath-007416	Arabidopsis thaliana	66.67	5.00e-66	242.00
IUUC-Ame-011281	Astyanax mexicanus	79.52	2.00e-79	286.00
IUUC-Bta-012940	Bos taurus	79.27	2.00e-81	293.00
IUUC-Bdi-014987	Brachypodium distachyon	62.35	4.00e-61	226.00
IUUC-Bol-016532	Brassica oleracea	68.52	3.00e-67	246.00
IUUC-Bra-017971	Brassica rapa	68.52	2.00e-67	246.00
IUUC-Cel-018620	Caenorhabditis elegans	73.29	4.00e-73	265.00
IUUC-Cja-019762	Callithrix jacchus	79.27	2.00e-81	293.00
IUUC-Cfa-021172	Canis familiaris	79.27	4.00e-81	292.00
IUUC-Cpo-021575	Cavia porcellus	79.27	2.00e-81	293.00
IUUC-Cre-022894	Chlamydomonas reinhardtii	62.50	2.00e-61	226.00
IUUC-Csa-024240	Chlorocebus sabaeus	76.22	1.00e-77	281.00
IUUC-Cho-024457	Choloepus hoffmanni	86.79	2.00e-24	104.00
IUUC-Cin-025708	Ciona intestinalis	77.44	1.00e-77	281.00
IUUC-Csv-026307	Ciona savignyi	79.88	3.00e-79	286.00
IUUC-Dre-027752	Danio rerio	78.66	2.00e-79	286.00
IUUC-Dno-028957	Dasypus novemcinctus	79.02	5.00e-71	258.00
IUUC-Dor-030637	Dipodomys ordii	78.66	5.00e-81	291.00
IUUC-Ete-033056	Echinops telfairi	78.05	1.00e-80	290.00
IUUC-Eca-034260	Equus caballus	79.27	2.00e-81	293.00
IUUC-Eeu-034785	Erinaceus europaeus	42.73	3.00e-12	62.40
IUUC-Fca-035879	Felis catus	79.27	2.00e-81	293.00
IUUC-Gmo-039023	Gadus morhua	74.23	3.00e-78	282.00
IUUC-Gga-040475	Gallus gallus	77.08	4.00e-68	249.00
IUUC-Gac-041574	Gasterosteus aculeatus	69.51	7.00e-72	261.00
IUUC-Gma-043338	Glycine max	66.05	2.00e-66	244.00
IUUC-Ggo-044713	Gorilla gorilla	84.80	2.00e-64	236.00
IUUC-Hsa-046948	Homo sapiens	79.27	2.00e-81	293.00
IUUC-Hvu-047147	Hordeum vulgare	62.73	6.00e-61	225.00
IUUC-Itr-048742	Ictidomys tridecemlineatus	79.27	2.00e-81	293.00
IUUC-Lch-049654	Latimeria chalumnae	80.98	2.00e-81	293.00
IUUC-Lpe-051422	Leersia perrieri	62.73	5.00e-61	225.00
IUUC-Loc-051920	Lepisosteus oculatus	79.27	2.00e-80	290.00
IUUC-Laf-054338	Loxodonta africana	79.27	2.00e-81	293.00
IUUC-Mcc-054927	Macaca mulatta	79.27	2.00e-81	293.00
IUUC-Meu-056831	Macropus eugenii	78.05	3.00e-80	289.00
IUUC-Mtr-058091	Medicago truncatula	65.43	4.00e-65	239.00
IUUC-Mga-059933	Meleagris gallopavo	70.71	7.00e-42	160.00
IUUC-Mmr-061433	Microcebus murinus	79.27	4.00e-81	292.00
IUUC-Mdo-061994	Monodelphis domestica	78.66	4.00e-80	288.00
IUUC-Mmu-063398	Mus musculus	78.05	9.00e-81	291.00
IUUC-Mac-064536	Musa acuminata	64.81	3.00e-64	236.00
IUUC-Mpu-066795	Mustela putorius furo	79.27	2.00e-81	293.00
IUUC-Mlu-067983	Myotis lucifugus	79.27	1.00e-81	294.00
IUUC-Nle-069720	Nomascus leucogenys	75.68	4.00e-52	194.00
IUUC-Opr-070723	Ochotona princeps	79.27	2.00e-81	293.00
IUUC-Ont-071509	Oreochromis niloticus	71.95	1.00e-73	267.00
IUUC-Oan-073541	Ornithorhynchus anatinus	76.60	9.00e-20	86.70
IUUC-Ocu-074044	Oryctolagus cuniculus	79.27	2.00e-81	293.00
IUUC-Oba-075612	Oryza barthii	62.35	6.00e-61	225.00
IUUC-Obr-076432	Oryza brachyantha	62.35	5.00e-61	225.00
IUUC-Ogl-077071	Oryza glaberrima	62.35	6.00e-61	225.00
IUUC-Ogu-078427	Oryza glumaepatula	62.35	6.00e-61	225.00
IUUC-Oin-079963	Oryza indica	62.35	6.00e-61	225.00
IUUC-Olo-080455	Oryza longistaminata	62.35	6.00e-61	225.00
IUUC-Oni-082562	Oryza nivara	62.35	6.00e-61	225.00
IUUC-Opu-083688	Oryza punctata	62.11	2.00e-60	224.00
IUUC-Oru-084472	Oryza rufipogon	62.35	6.00e-61	225.00
IUUC-Osa-085623	Oryza sativa	62.35	6.00e-61	225.00
IUUC-Oga-088366	Otolemur garnettii	79.27	2.00e-81	293.00
IUUC-Oar-089754	Ovis aries	78.66	5.00e-81	291.00
IUUC-Ptr-090679	Pan troglodytes	78.66	3.00e-81	292.00
IUUC-Psi-093472	Pelodiscus sinensis	84.68	9.00e-63	230.00
IUUC-Ppa-095568	Physcomitrella patens	67.90	1.00e-67	248.00
IUUC-Pfo-097314	Poecilia formosa	72.56	7.00e-74	268.00
IUUC-Pab-098562	Pongo abelii	79.27	2.00e-81	293.00
IUUC-Pop-099506	Populus trichocarpa	66.67	3.00e-66	243.00
IUUC-Pca-101030	Procavia capensis	71.34	1.00e-70	257.00
IUUC-Ppe-101757	Prunus persica	67.28	1.00e-66	244.00
IUUC-Pva-102948	Pteropus vampyrus	79.88	8.00e-82	294.00
IUUC-Rno-105014	Rattus norvegicus	77.44	2.00e-80	290.00
IUUC-Sha-107297	Sarcophilus harrisii	78.53	4.00e-80	289.00
IUUC-Sit-110317	Setaria italica	62.96	3.00e-61	226.00
IUUC-Sly-111332	Solanum lycopersicum	69.14	3.00e-67	246.00
IUUC-Stu-112719	Solanum tuberosum	69.14	3.00e-67	246.00
IUUC-Sbi-114869	Sorghum bicolor	62.96	2.00e-61	226.00
IUUC-Ssc-116009	Sus scrofa	79.27	2.00e-81	293.00
IUUC-Tru-117527	Takifugu rubripes	72.56	3.00e-74	269.00
IUUC-Tsy-119195	Tarsius syrichta	75.89	5.00e-65	238.00
IUUC-Tni-120417	Tetraodon nigroviridis	71.34	6.00e-73	265.00
IUUC-Tca-120972	Theobroma cacao	68.52	4.00e-67	245.00
IUUC-Tae-124763	Triticum aestivum	62.73	1.00e-60	224.00
IUUC-Tur-126831	Triticum urartu	62.73	6.00e-61	225.00
IUUC-Tbe-128019	Tupaia belangeri	79.43	2.00e-70	256.00
IUUC-Ttr-129013	Tursiops truncatus	79.27	2.00e-81	293.00
IUUC-Vvi-131214	Vitis vinifera	67.90	2.00e-66	243.00
IUUC-Xtr-132182	Xenopus tropicalis	80.49	6.00e-81	291.00
IUUC-Xma-133877	Xiphophorus maculatus	72.56	9.00e-74	268.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence