iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000016455.1	ENSSHAT00000019528.1	ENSSHAP00000019371.1
ENSSHAG00000016455.1	ENSSHAT00000019529.1	ENSSHAP00000019372.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E2/Other	95.21	3.00e-93	337.00	IUUC-Hsa-046948

Active Site

Position(s)	Description	Evidence
116	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR008716-1}

Organism

Sarcophilus harrisii

Functional Description
(View)

E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage.

Protein Sequence
(Fasta)

MADEATRRVV SEIPVLKTNA GPRDRELWVQ RLKEEYQALI RYVENNKNAD NDWFRLESNK 60
EGTRWFGKCW YIHDLLKYEF DLEFDIPITY PSTAPEIAVP ELDGKTAKMY RGGKICLTEH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGTCACCTC CTGGAGGGCA GGGACCGTTT TTGTCTTTCC TTTGTATTCA AAGTACTTAG 60
CACCGTGTTA GACACAAGCT GGGCTTGGAT ACCTACTTGC TGACTTGACA AATCCATTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR016135--UBQ-conjugating_enzyme/RWD
IPR014806--Ufc1

Pfam

PF08694--UFC1

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0071568--F:UFM1 transferase activity
GO:1990592--P:protein K69-linked ufmylation
GO:0034976--P:response to endoplasmic reticulum stress

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000219	Aegilops tauschii	67.90	1.00e-30	124.00
IUUC-Aml-001773	Ailuropoda melanoleuca	94.01	9.00e-94	335.00
IUUC-Atr-002519	Amborella trichopoda	66.67	1.00e-68	251.00
IUUC-Aca-004597	Anolis carolinensis	88.96	6.00e-87	312.00
IUUC-Aly-005549	Arabidopsis lyrata	65.45	2.00e-66	244.00
IUUC-Ath-007416	Arabidopsis thaliana	65.45	2.00e-66	244.00
IUUC-Ame-011281	Astyanax mexicanus	86.75	1.00e-86	311.00
IUUC-Bta-012940	Bos taurus	95.81	3.00e-95	339.00
IUUC-Bdi-014987	Brachypodium distachyon	63.80	1.00e-62	231.00
IUUC-Bol-016532	Brassica oleracea	64.46	2.00e-66	244.00
IUUC-Bra-017971	Brassica rapa	64.46	1.00e-66	244.00
IUUC-Cel-018620	Caenorhabditis elegans	72.50	9.00e-72	261.00
IUUC-Cja-019762	Callithrix jacchus	95.78	2.00e-94	337.00
IUUC-Cfa-021172	Canis familiaris	94.61	2.00e-94	337.00
IUUC-Cpo-021575	Cavia porcellus	95.21	1.00e-94	337.00
IUUC-Cre-022894	Chlamydomonas reinhardtii	61.25	2.00e-60	224.00
IUUC-Csa-024240	Chlorocebus sabaeus	91.02	3.00e-90	323.00
IUUC-Cho-024457	Choloepus hoffmanni	92.73	5.00e-27	113.00
IUUC-Cin-025708	Ciona intestinalis	75.46	2.00e-75	273.00
IUUC-Csv-026307	Ciona savignyi	77.30	2.00e-76	277.00
IUUC-Cgl-026671	Colletotrichum gloeosporioides	24.47	4.00e-02	31.60
IUUC-Dre-027752	Danio rerio	86.75	2.00e-87	314.00
IUUC-Dno-028957	Dasypus novemcinctus	95.10	7.00e-81	291.00
IUUC-Dor-030637	Dipodomys ordii	94.61	4.00e-94	336.00
IUUC-Dme-032033	Drosophila melanogaster	78.53	6.00e-80	289.00
IUUC-Ete-033056	Echinops telfairi	93.41	3.00e-93	333.00
IUUC-Eca-034260	Equus caballus	95.21	1.00e-94	337.00
IUUC-Eeu-034785	Erinaceus europaeus	58.18	2.00e-19	87.00
IUUC-Fca-035879	Felis catus	96.93	4.00e-93	333.00
IUUC-Gmo-039023	Gadus morhua	81.71	2.00e-84	304.00
IUUC-Gga-040475	Gallus gallus	82.52	2.00e-71	260.00
IUUC-Gac-041574	Gasterosteus aculeatus	79.27	8.00e-79	285.00
IUUC-Gma-043338	Glycine max	64.24	1.00e-66	244.00
IUUC-Ggo-044713	Gorilla gorilla	93.70	1.00e-70	257.00
IUUC-Hsa-046948	Homo sapiens	95.21	1.00e-94	337.00
IUUC-Hvu-047147	Hordeum vulgare	64.60	4.00e-62	229.00
IUUC-Itr-048742	Ictidomys tridecemlineatus	95.21	1.00e-94	337.00
IUUC-Lch-049654	Latimeria chalumnae	88.41	3.00e-88	316.00
IUUC-Lpe-051422	Leersia perrieri	64.60	1.00e-62	231.00
IUUC-Loc-051920	Lepisosteus oculatus	87.95	1.00e-88	318.00
IUUC-Laf-054338	Loxodonta africana	95.21	1.00e-94	337.00
IUUC-Mcc-054927	Macaca mulatta	95.21	1.00e-94	337.00
IUUC-Meu-056831	Macropus eugenii	99.39	6.00e-95	338.00
IUUC-Mtr-058091	Medicago truncatula	63.64	2.00e-65	241.00
IUUC-Mga-059933	Meleagris gallopavo	75.76	1.00e-44	170.00
IUUC-Mmr-061433	Microcebus murinus	94.61	2.00e-94	337.00
IUUC-Mdo-061994	Monodelphis domestica	97.55	5.00e-93	332.00
IUUC-Mmu-063398	Mus musculus	93.41	7.00e-94	335.00
IUUC-Mac-064536	Musa acuminata	63.19	4.00e-64	236.00
IUUC-Mpu-066795	Mustela putorius furo	95.81	3.00e-95	339.00
IUUC-Mlu-067983	Myotis lucifugus	95.21	4.00e-94	336.00
IUUC-Nle-069720	Nomascus leucogenys	97.30	3.00e-62	229.00
IUUC-Opr-070723	Ochotona princeps	95.81	3.00e-95	339.00
IUUC-Ont-071509	Oreochromis niloticus	81.44	9.00e-82	295.00
IUUC-Oan-073541	Ornithorhynchus anatinus	91.49	3.00e-23	99.00
IUUC-Ocu-074044	Oryctolagus cuniculus	96.93	2.00e-93	333.00
IUUC-Oba-075612	Oryza barthii	63.80	8.00e-63	232.00
IUUC-Obr-076432	Oryza brachyantha	63.80	9.00e-63	232.00
IUUC-Ogl-077071	Oryza glaberrima	63.80	8.00e-63	232.00
IUUC-Ogu-078427	Oryza glumaepatula	63.80	8.00e-63	232.00
IUUC-Oin-079963	Oryza indica	63.80	8.00e-63	232.00
IUUC-Olo-080455	Oryza longistaminata	63.80	8.00e-63	232.00
IUUC-Oni-082562	Oryza nivara	63.80	8.00e-63	232.00
IUUC-Opu-083688	Oryza punctata	63.98	4.00e-62	230.00
IUUC-Oru-084472	Oryza rufipogon	63.80	8.00e-63	232.00
IUUC-Osa-085623	Oryza sativa	63.80	8.00e-63	232.00
IUUC-Oga-088366	Otolemur garnettii	95.21	1.00e-94	337.00
IUUC-Oar-089754	Ovis aries	95.81	5.00e-95	339.00
IUUC-Ptr-090679	Pan troglodytes	94.61	2.00e-94	337.00
IUUC-Psi-093472	Pelodiscus sinensis	93.50	1.00e-67	247.00
IUUC-Ppa-095568	Physcomitrella patens	68.32	2.00e-67	248.00
IUUC-Pfo-097314	Poecilia formosa	80.49	1.00e-79	288.00
IUUC-Pab-098562	Pongo abelii	95.81	8.00e-95	338.00
IUUC-Pop-099506	Populus trichocarpa	64.46	2.00e-66	244.00
IUUC-Pca-101030	Procavia capensis	87.95	1.00e-83	301.00
IUUC-Ppe-101757	Prunus persica	64.46	1.00e-66	244.00
IUUC-Pva-102948	Pteropus vampyrus	96.41	2.00e-95	340.00
IUUC-Rno-105014	Rattus norvegicus	93.41	1.00e-93	334.00
IUUC-Sit-110317	Setaria italica	63.19	6.00e-62	229.00
IUUC-Sly-111332	Solanum lycopersicum	64.85	4.00e-66	243.00
IUUC-Stu-112719	Solanum tuberosum	64.85	4.00e-66	243.00
IUUC-Sbi-114869	Sorghum bicolor	63.19	5.00e-62	229.00
IUUC-Ssc-116009	Sus scrofa	95.21	1.00e-94	337.00
IUUC-Tru-117527	Takifugu rubripes	82.21	3.00e-81	293.00
IUUC-Tsy-119195	Tarsius syrichta	92.91	3.00e-75	273.00
IUUC-Tni-120417	Tetraodon nigroviridis	82.21	4.00e-81	293.00
IUUC-Tca-120972	Theobroma cacao	65.66	5.00e-67	246.00
IUUC-Tae-124763	Triticum aestivum	64.60	9.00e-62	228.00
IUUC-Tur-126831	Triticum urartu	64.60	4.00e-62	229.00
IUUC-Tbe-128019	Tupaia belangeri	97.16	9.00e-81	291.00
IUUC-Ttr-129013	Tursiops truncatus	95.81	3.00e-95	339.00
IUUC-Vvi-131214	Vitis vinifera	64.46	2.00e-65	240.00
IUUC-Xtr-132182	Xenopus tropicalis	90.74	2.00e-88	317.00
IUUC-Xma-133877	Xiphophorus maculatus	80.49	2.00e-79	287.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence